Research Topics
Genomes and Genes | Rafael SimoSummaryAffiliation: Hospital Universitari Vall d'Hebron Country: Spain Publications
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Publications
Apolipoprotein A1 is overexpressed in the retina of diabetic patientsRafael Simo
CIBERDEM Carlos III Health Institute, Barcelona, Spain
Am J Ophthalmol 147:319-325.e1. 2009..To compare apolipoprotein A1 (ApoA1) expression in the retina from diabetic and nondiabetic donors...
Neurodegeneration is an early event in diabetic retinopathy: therapeutic implicationsRafael Simo
Diabetes and Metabolism Research Unit, Vall d Hebron Institut de Recerca, Barcelona, Spain
Br J Ophthalmol 96:1285-90. 2012..However, clinical trials to determine the safety and effectiveness of this non-invasive route, as well as a standardisation of the methods for monitoring neurodegeneration, are needed...
Prevalence and risk factors accounting for true silent myocardial ischemia: a pilot case-control study comparing type 2 diabetic with non-diabetic control subjectsCristina Hernandez
CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Spain
Cardiovasc Diabetol 10:9. 2011....- Encephalopathy associated with autoimmune thyroid disease in patients with Graves' disease: clinical manifestations, follow-up, and outcomesGianluca Tamagno
Department of Endocrinology and Diabetes Mellitus, St Vincent s University Hospital, University College Dublin, Dublin, Ireland
BMC Neurol 10:27. 2010..Almost all EAATD patients are affected by Hashimoto's thyroiditis (HT), although fourteen EAATD patients with Graves' disease (GD) have been also reported... - Deficit of somatostatin in the vitreous fluid of patients with diabetic macular edemaRafael Simo
Diabetes Research Unit, Endocrinology Division, Hospital Universitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Diabetes Care 30:725-7. 2007 - Different effects of thiazolidinediones on cardiovascular risk in patients with type 2 diabetes mellitus: pioglitazone versus rosiglitazoneR Simo
Diabetes and Metabolism Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Curr Drug Saf 5:234-44. 2010..By contrast, it seems that rosiglitazone increases cardiovascular risk. The difference in lipid profile may be the main factor accounting for the superiority of pioglitazone in reducing cardiovascular risk... - Fenofibrate for diabetic retinopathyRafael Simo
Diabetes Research Unit, Vall d Hebron University Hospital, 08035 Barcelona, Spain
Lancet 370:1667-8. 2007 - Intravitreous anti-VEGF for diabetic retinopathy: hopes and fears for a new therapeutic strategyR Simo
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas CIBERDEM Carlos III Health Institute, Institut de Recerca Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain
Diabetologia 51:1574-80. 2008..In this regard, head-to-head studies designed to evaluate not only the efficacy, but also the systemic adverse effects of these drugs in a high-risk population such as diabetic patients are warranted... - Elevation of apolipoprotein A-I and apolipoprotein H levels in the vitreous fluid and overexpression in the retina of diabetic patientsRafael Simo
Diabetes Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Arch Ophthalmol 126:1076-81. 2008.... - The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier--implications for the pathogenesis of diabetic retinopathyRafael Simo
CIBER de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Instituto de Salud Carlos III ISCIII, Unitat de Diabetis i Metabolisme, Institut de Recerca Hospital Universitari Vall d Hebron, Passeig Vall d Hebron 119 129, 08035 Barcelona, Spain
J Biomed Biotechnol 2010:190724. 2010..By contrast, the effects of diabetes on the RPE and in particular on its secretory activity have received less attention. In this regard, new therapeutic strategies addressed to modulating RPE impairment are warranted... - Sustained virological response correlates with reduction in the incidence of glucose abnormalities in patients with chronic hepatitis C virus infectionRafael Simo
Diabetes Research Unit, Endocrinology Division, Hospital Universitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Diabetes Care 29:2462-6. 2006..The main aim of this study was to compare the incidence of glucose abnormalities (diabetes plus impaired fasting glucose) between HCV-infected patients with or without sustained virological response (SVR) after antiviral therapy... - Intravitreous hepatocyte growth factor in patients with proliferative diabetic retinopathy: a case-control studyRafael Simo
Diabetes Research Unit, Endocrinology Division, Hospital Univesitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Diabetes Res Clin Pract 71:36-44. 2006..Our findings suggest that HGF is related to pathological conditions in which fibroproliferative processes or wound healing are involved rather than with angiogenesis itself... - Measuring permeability in human retinal epithelial cells (ARPE-19): implications for the study of diabetic retinopathyMarta Garcia-Ramírez
Diabetes and Metabolism Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Universitat Autònoma de Barcelona and CIBER de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Instituto de Salud Carlos III ISCIII, Barcelona, Spain
Methods Mol Biol 763:179-94. 2011..Finally, we provide the methods required for confocal immunofluorescence detection of the TJ proteins, as well as for assessing the capacity of ARPE-19 cells to retain their functional properties... - Biological variation of lipoprotein(a) in a diabetic population. Analysis of the causes and clinical implicationsCristina Hernandez
Diabetes Research Unit, Hospital General Vall d Hebron, Barcelona, Spain
Clin Chem Lab Med 41:1075-80. 2003..Finally, triglycerides and AER are the main factors influencing Lp(a) serum levels in the diabetic population... - Erythropoietin is expressed in the human retina and it is highly elevated in the vitreous fluid of patients with diabetic macular edemaCristina Hernandez
Diabetes Research Unit, Endocrinology Division, Hospital Universitari Vall d Hebron, Passeig Vall d Hebron 119 129, 08035 Barcelona, Spain
Diabetes Care 29:2028-33. 2006.... - Deficit of somatostatin-like immunoreactivity in the vitreous fluid of diabetic patients: possible role in the development of proliferative diabetic retinopathyRafael Simo
Diabetes Unit, Division of Endocrinology, Hospital General Universitari Vall d Hebron, Barcelona, Spain
Diabetes Care 25:2282-6. 2002..To evaluate the vitreous levels of somatostatin-like immunoreactivity (SLI) in patients with proliferative diabetic retinopathy (PDR)... - Lowered cortistatin expression is an early event in the human diabetic retina and is associated with apoptosis and glial activationEsther Carrasco
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Instituto de Salut Carlos III ISCIII, Barcelona, Spain
Mol Vis 14:1496-502. 2008..Retinal neurodegeneration was assessed by measuring glial fibrilar acidic protein (GFAP) by confocal laser microscopy and counting the apoptotic TUNEL positive cells in which nuclear fragmentation as well as condensation were present... - Expression of erythropoietin and its receptor in the human retina: a comparative study of diabetic and nondiabetic subjectsMarta Garcia-Ramírez
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas, Instituto de Salud Carlos III, Diabetes Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
Diabetes Care 31:1189-94. 2008..To gain insight into the mechanisms responsible for the regulation of Epo production in the retina, we also assessed retinal expression of hypoxia-inducible factors (HIF-1alpha and HIF-2alpha)... - Lipoprotein(a) as a risk factor for cardiovascular mortality in type 2 diabetic patients: a 10-year follow-up studyCristina Hernandez
Diabetes Research Unit, Endocrinology Division, Hospital Universitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Diabetes Care 28:931-3. 2005 - CD4-CD8 and CD28 expression in T cells infiltrating the vitreous fluid in patients with proliferative diabetic retinopathy: a flow cytometric analysisAna Canton
Diabetes Research Unit, Division of Endocrinology, Hospital General Universitari Vall d Hebron, Pg Vall d Hebron 119 129, Barcelona, Spain
Arch Ophthalmol 122:743-9. 2004.... - Somatostatin molecular variants in the vitreous fluid: a comparative study between diabetic patients with proliferative diabetic retinopathy and nondiabetic control subjectsCristina Hernandez
Diabetes Research Unit, Endocrinology Division, Hospital Universitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Diabetes Care 28:1941-7. 2005..Somatostatin-14, somatostatin-28 and cortistatin were measured by radioimmunoassay but separation by high-performance liquid chromatography was required to measure somatostatin-14... - Effect of intensive insulin therapy on macular biometrics, plasma VEGF and its soluble receptor in newly diagnosed diabetic patientsCristina Hernandez
CIBERDEM ISCIII, Institut de Recerca Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain
Diabetes Metab Res Rev 26:386-92. 2010.... - Erythropoietin protects retinal pigment epithelial cells against the increase of permeability induced by diabetic conditions: essential role of JAK2/ PI3K signalingMarta Garcia-Ramírez
Diabetes and Metabolism Research Unit, Vall d Hebron Research Institute, Universitat Autonoma de Barcelona, Spain
Cell Signal 23:1596-602. 2011..We conclude that RPE disruption induced by high glucose plus IL-1β is prevented by Epo through the downstream signaling of JAK2 and PI3K/AKT pathways... - Lower somatostatin expression is an early event in diabetic retinopathy and is associated with retinal neurodegenerationEsther Carrasco
Diabetes Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Diabetes Care 30:2902-8. 2007..To test the hypothesis that a reduction of somatostatin (SST) in the retina exists in patients without clinically detectable diabetic retinopathy and that it is associated with retinal neurodegeneration... - Intravitreous leptin concentrations in patients with proliferative diabetic retinopathyCristina Hernandez
Diabetes Research Unit, Hospital General Universitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Retina 24:30-5. 2004..The aim of the present study was to investigate the source of intravitreal leptin and to determine whether it is related to PDR activity... - Free insulin growth factor-I and vascular endothelial growth factor in the vitreous fluid of patients with proliferative diabetic retinopathyRafael Simo
Division of Endocrinology, Diabetes Research Unit, Hospital General Universitari Vall d Hebron, Barcelona, Spain
Am J Ophthalmol 134:376-82. 2002..To investigate the relationship between insulin-like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in the vitreous fluid of diabetic patients with proliferative diabetic retinopathy (PDR)... - Lipopolysaccharide-binding protein and soluble CD14 in the vitreous fluid of patients with proliferative diabetic retinopathyCristina Hernandez
CIBERDEM ISCIII, Universitat Autonoma de Barcelona, Barcelona, Spain
Retina 30:345-52. 2010..The purpose of this study was to compare intravitreous levels of lipopolysaccharide-binding protein and soluble CD14 (sCD14) between patients with proliferative diabetic retinopathy (PDR) and nondiabetic subjects... - Effects of high glucose concentration on the barrier function and the expression of tight junction proteins in human retinal pigment epithelial cellsMarta Villarroel
Diabetes and Metabolism Research Unit, Institut de Recerca Hospital Vall d Hebron, Universitat Autonoma de Barcelona, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Exp Eye Res 89:913-20. 2009..Further studies addressed to unravel the complexity of permeability regulation in RPE are needed... - Angiogenic and antiangiogenic factors in proliferative diabetic retinopathyRafael Simo
Diabetes Research Unit, Endocrinology Division, Hospital Universitari Vall d Hebron, Barcelona, Spain
Curr Diabetes Rev 2:71-98. 2006..The main antiangiogenic factor is the pigment epithelium derived factor (PEDF) but the transforming growth factor beta (TGF-beta), thrombospondin (TSP) and somatostatin are also among the intraocullary synthesized antiangiogenic factors... - Erythropoietin produced by the retina: its role in physiology and diabetic retinopathyCristina Hernandez
CIBERDEM, Diabetes and Metabolism Research Unit, Vall d Hebron Research Institute VHIR, Universitat Autonoma de Barcelona, Barcelona, Spain
Endocrine 41:220-6. 2012..Finally, the reasons as to why Epo could be contemplated as a potential new treatment for the early stages of diabetic retinopathy will be given... - Lower zinc-alpha2-glycoprotein production by adipose tissue and liver in obese patients unrelated to insulin resistanceDavid M Selva
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Universitat Autonoma de Barcelona, Barcelona, Spain
J Clin Endocrinol Metab 94:4499-507. 2009..Zinc-alpha2 glycoprotein (ZAG) has been proposed as a new candidate in the pathogenesis of obesity, but most of the information stems from studies performed in rodents and in vitro assays... - Glucose abnormalities are an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis CAlbert Lecube
Diabetes Research Unit, Endocrinology Division, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain
Am J Gastroenterol 102:2189-95. 2007..This study investigated whether glucose abnormalities (impaired fasting glucose and type 2 diabetes) influence the response to antiviral therapy with interferon plus ribavirin in patients with chronic hepatitis C... - Molecular Mechanism of TNFα-Induced Down-Regulation of SHBG ExpressionRafael Simo
Diabetes and Metabolism Research Unit, Vall d Hebron Institut de Recerca, Passeig Vall d Hebron 119 129, Barcelona, Spain
Mol Endocrinol 26:438-46. 2012..We conclude that sustained exposition to elevated levels of TNFα decreases SHBG production by reducing hepatic HNF-4α levels via NF-κB activation in HepG2 cells... - Neuroprotection in diabetic retinopathyCristina Hernandez
CIBERDEM and Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca, Universitat Autonoma de Barcelona, Spain
Curr Diab Rep 12:329-37. 2012..In this review we will focus on neurotrophic factors already synthesized by the retina in physiological conditions as a new therapy strategy for neuroprotection... - Diabetes is an independent risk factor for severe nocturnal hypoxemia in obese patients. A case-control studyAlbert Lecube
CIBER de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Instituto de Salud Carlos III ISCIII, Diabetes and Metabolism Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Barcelona, Spain
PLoS ONE 4:e4692. 2009..The aim of this cross-sectional case-control study was to evaluate whether obese patients with T2DM are more prone to severe SAHS than obese non-diabetic subjects... - Albumin excretion rate is not affected by asymptomatic urinary tract infection: a prospective studyCristina Hernandez
Diabetes Research Unit, Division of Endocrinology, Hospital Universitari Vall d Hebron, Pg Vall d Hebron, Barcelona, Spain
Diabetes Care 27:1565-9. 2004..The aim of the study was to evaluate whether asymptomatic urinary tract infection (UTI) significantly influences the level of albumin excretion rate (AER) in diabetic patients... - Metabolic fingerprints of proliferative diabetic retinopathy: an 1H-NMR-based metabonomic approach using vitreous humorIgnasi Barba
Laboratory of Experimental Cardiology, Heart Department, Hospital Universitari Vall d Hebron, Barcelona, Spain
Invest Ophthalmol Vis Sci 51:4416-21. 2010..To explore the metabolic profile of vitreous fluid of patients with proliferative diabetic retinopathy (PDR) using 1H-NMR-based metabonomic analysis... - Normoalbuminuric type 1 diabetic patients with retinopathy have an impaired tubular response to desmopressin: its relationship with plasma endothelin-1Cristina Hernandez
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas, Diabetes Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona 08035, Spain
J Clin Endocrinol Metab 94:2060-5. 2009.... - Asymptomatic sleep-disordered breathing in premenopausal women awaiting bariatric surgeryAlbert Lecube
CIBER de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Instituto de Salud Carlos III ISCIII, Diabetes Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Passeig Vall d Hebron 119 129, Barcelona, Spain
Obes Surg 20:454-61. 2010..To evaluate the prevalence and characteristics of sleep apnea-hypopnea syndrome (SAHS) and obesity hypoventilation syndrome (OHS) in morbidly obese pre-menopausal women included in a program of bariatric surgery... - Update on cardiovascular safety of PPARgamma agonists and relevance to medicinal chemistry and clinical pharmacologyAndreea Ciudin
Diabetes and Metabolism Research Unit, CIBER de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Instituto de Salud Carlos III, Vall d Hebron Institut de Recerca VHIR, Hospital Universitari Vall d Hebron, Universitatautonoma de Barcelona, Barcelona, Spain
Curr Top Med Chem 12:585-604. 2012..However, further experimental and clinical studies evaluating the theoretical benefit and safety of this therapeutic strategy are needed... - Effects of hypolipidemic treatment on serum markers of vascular inflammation in dyslipidemic menCristina Hernandez
Endocrinology Division, Hospital General Vall d Hebron, Barcelona, Spain
Med Sci Monit 9:CR114-9. 2003..The purpose of our study was to assess the effect of hypolipidemiant drugs on serum markers of vascular inflammation (E-Selectin, VCAM-1 and MCP-1) in dyslipidemic men without cardiovascular disease... - Non-invasive methods of glucose measurement: current status and future perspectivesAndreea Ciudin
Diabetes and Metabolism Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Pg Vall d Hebron 119 129, 08035 Barcelona, Spain
Curr Diabetes Rev 8:48-54. 2012..In this paper we will give an overview of the noninvasive devices tested so far and their implications for the clinical management of the diabetic patient... - Glucose abnormalities in non-alcoholic fatty liver disease and chronic hepatitis C virus infection: the role of iron overloadAlbert Lecube
CIBER de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Instituto de Salud Carlos III ISCIII, Diabetes and Metabolism Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Barcelona, Spain
Diabetes Metab Res Rev 25:403-10. 2009..Therefore, glucose abnormalities, and specially type 2 diabetes, should be taken into account when evaluating serum ferritin levels in patients with HCV infection... - Insulin resistance is related to impaired lung function in morbidly obese women: a case-control studyAlbert Lecube
CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Diabetes and Metabolism Research Unit, Institut de Recerca Hospital Universitari Vall d Hebron, Passeig Vall d Hebron 119 129, Barcelona, Spain
Diabetes Metab Res Rev 26:639-45. 2010..The aim of the study is to determine whether obese patients with insulin resistance without diabetes have reduced pulmonary function in comparison with non-diabetic obese subjects without insulin resistance... - IL1β down-regulation of sex hormone-binding globulin production by decreasing HNF-4α via MEK-1/2 and JNK MAPK pathwaysRafael Simo
Diabetes and Metabolism Research Unit, Vall d Hebron Institut de Recerca, Universitat Autònoma de Barcelona and Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas Instituto de Salud Carlos III, 08035 Barcelona, Spain
Mol Endocrinol 26:1917-27. 2012..In addition, our findings suggest that IL1β could be involved the low plasma SHBG levels reported in chronic low-grade inflammatory diseases... - Prevention and treatment of diabetic retinopathy: evidence from large, randomized trials. The emerging role of fenofibrateRafael Simo
CIBERDEM, Vall Hebron Institut de Recerca VHIR, Universitat Autonoma de Barcelona, Barcelona, Spain
Rev Recent Clin Trials 7:71-80. 2012..The results of ACCORD-EYE, together with those of FIELD, identify a place for fenofibrate for the prevention of retinopathy alongside intensive management of traditional risk factors, such as hyperglycemia and high blood pressure... - [Treatment of diabetes mellitus: general goals, and clinical practice management]Rafael Simo
Sección de Endocrinología, Hospital General Vall d Hebron, Barcelona, Spain
Rev Esp Cardiol 55:845-60. 2002..Therefore, the treatment selection will depend on the stage of the disease and the individual characteristics of the patient. This article examines the general goals of the treatment and reviews the management of type 2 diabetes... - Potential role of tumor necrosis factor-α in downregulating sex hormone-binding globulinRafael Simo
Diabetes and Metabolism Research Unit, Vall d Hebron Institut de Recerca, Universitat Autonoma de Barcelona, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas ISCIII, Barcelona, Spain
Diabetes 61:372-82. 2012..Our results suggest that TNF-α plays an important role downregulating SHBG in chronic low-grade inflammatory diseases such as obesity and type 2 diabetes... - Can augmentation index substitute aortic pulse wave velocity in the assessment of central arterial stiffness in type 1 diabetes?Gemma Llauradó
Department of Diabetes, Endocrinology and Nutrition, Hospital de Sabadell, Corporació Sanitària i Universitària Parc Taulí, Universitat Autonoma de Barcelona, Parc Tauli, 08208 Sabadell, Spain
Acta Diabetol 49:S253-7. 2012..342; healthy subjects: p = 0.976). Our findings suggest that AIx@HR75 should not be used as a substitute for aPWV for measuring AS in type 1 diabetes... - Usefulness of the vitreous fluid analysis in the translational research of diabetic retinopathyOlga Simó-Servat
Department of Endocrinology, Hospital Vall d Hebron, Barcelona, Spain
Mediators Inflamm 2012:872978. 2012..Finally, a more personalized treatment based on vitreous fluid analysis aiming to reduce the burden associated with DR is suggested... - Diabetes is the main factor accounting for hypomagnesemia in obese subjectsAlbert Lecube
CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Diabetes and Metabolism Research Unit, Endocrinology Department, Universitat Autonoma de Barcelona, Barcelona, Spain
PLoS ONE 7:e30599. 2012..Type 2 diabetes (T2DM) and obesity are associated with magnesium deficiency. We aimed to determine whether the presence of type 2 diabetes and the degree of metabolic control are related to low serum magnesium levels in obese individuals... - Iron deficiency in obese postmenopausal womenAlbert Lecube
Obesity Research Unit, Endocrinology Division, Hospital General Vall d Hebron, Barcelona, Spain
Obesity (Silver Spring) 14:1724-30. 2006..This study evaluates whether the iron deficiency suggested in children and adolescents with overweight is also present with increasing age... - Phagocytic activity is impaired in type 2 diabetes mellitus and increases after metabolic improvementAlbert Lecube
Diabetes and Metabolism Research Unit, CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Vall d Hebron Institut de Recerca, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain
PLoS ONE 6:e23366. 2011.... - Molecular Implications of the PPARs in the Diabetic EyeAndreea Ciudin
Unidad de Investigación en Diabetes y Metabolism, CIBER de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Instituto de Salud Carlos III, Instituto de Investigación Vall d Hebron, Universitat Autonoma de Barcelona, Paseo Vall d Hebron, 119 129 Barcelona, Spain
PPAR Res 2013:686525. 2013..2010))... - Neurodegeneration: An early event of diabetic retinopathyMarta Villarroel
Marta Villarroel, Andreea Ciudin, Cristina Hernández, Rafael Simó, Diabetes and Metabolism Research Unit Institut de Recerca Hospital Universitari Vall D Hebron, Universitat Autonoma de Barcelona, Barcelona 08035, Spain
World J Diabetes 1:57-64. 2010..Whether these novel therapies will eventually supplement or prevent the need for laser photocoagulation or vitrectomy awaits the results of additional clinical research... - Study of the potential association of adipose tissue GLP-1 receptor with obesity and insulin resistanceJoan Vendrell
University Hospital of Tarragona Joan XXIII, IISPV, Rovira i Virgili University, Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, 43007 Tarragona, Spain
Endocrinology 152:4072-9. 2011..Altogether these results indicate that the GLP-1/GLP-1R system in AT represents another potential candidate for improving insulin sensitivity in obese patients... - Strategies for blocking angiogenesis in diabetic retinopathy: from basic science to clinical practiceCristina Hernandez
Hospital Universitari Vall d Hebron, Diabetes and Metabolism Research Unit, Endocrinology Division, Pg Vall d Hebron, Barcelona, Spain
Expert Opin Investig Drugs 16:1209-26. 2007.... - Arterial stiffness is increased in patients with type 1 diabetes without cardiovascular disease: a potential role of low-grade inflammationGemma Llauradó
Department of Diabetes, Hospital of Sabadell, Corporació Sanitària i Universitària Parc Taulí, Universitat Autonoma de Barcelona, Sabadell, Spain
Diabetes Care 35:1083-9. 2012..To investigate the relationship between arterial stiffness and low-grade inflammation in subjects with type 1 diabetes without clinical cardiovascular disease...