Research Topics
Species | A SanzSummaryAffiliation: Hospital Universitario Country: Spain Publications
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Detail Information
Publications
Treatment of osteoporosis and hip fractures in a Spanish health areaL Briongos
Documentation Unit Rio Hortega University Hospital, Valladolid, Spain
Eur Rev Med Pharmacol Sci 17:266-8. 2013....
The deleterious effect of bariatric surgery on cortical and trabecular bone density in the femurs of non-obese, type 2 diabetic Goto-Kakizaki ratsJosé Luis Pérez-Castrillón
Institute of Endocrinology, Rio Hortega University Hospital, C Dulzaina 2, 47016, Valladolid, Spain
Obes Surg 22:1755-60. 2012..The aim of this study was to evaluate bone microstructural properties and volumetric bone mineral density (vBMD) in type 2 diabetic Goto-Kakizaki non-obese rats after gastrojejunal bypass and their relationship with hormonal parameters...
Haplotypes of intron 4 of the estrogen receptor alpha gene and hip fractures: a replication study in CaucasiansJavier Velasco
Department of Internal Medicine, Hospital U, M, Valdecilla, University of Cantabria, RETICEF, Santander, Spain
BMC Med Genet 11:16. 2010..The aim of this study was to investigate whether such association is also present in Caucasians...
Effect of beta-blockers on bone mass and biomechanical parameters of the femoral neck in males with acute myocardial infarctionJose L Perez-Castrillon
Departamento de Medicina Interna, Hospital Universitario Rio Hortega, Facultad de Medicina de Valladolid, C Torquemada s n, Valladolid 47010, Spain
Joint Bone Spine 74:259-62. 2007..Evaluate the effect of cardioselective beta-blockers on bone mass and biomechanical properties of the femoral neck in males with acute myocardial infarction...
Ghrelin and bone mass in postmenopausal hypertensive womenJose L Perez-Castrillon
Department of Internal Medicine, Rio Hortega University Hospital, Valladolid, Spain
Ann Nutr Metab 51:223-7. 2007..It also has vasodilator effects which reduce blood pressure and stimulate in vitro, bone formation...
OST risk index and calcaneus bone densitometry in osteoporosis diagnosisJose L Perez-Castrillon
Hospital Universitario Río Hortega Val ladolid, Spain
J Clin Densitom 10:404-7. 2007..The combination of the calcaneal DXA with the OST index did not improve the value of each of the separate techniques. The OST index is useful in women to facilitate the densitometry indication for hip and/or spine...
New approaches to atherosclerotic cardiovascular disease. the potentialities of torcetrapibJosé Luis Pérez-Castrillón
Hospital Rio Hortega University of Valladolid, Valladolid, Spain
Recent Pat Cardiovasc Drug Discov 1:109-14. 2006..The raising HDL-cholesterol with torcetrapib could be a new approach to atherosclerotic cardiovascular disease although new trials based on hard clinical end points are necessary...
Atherosclerosis and osteoporosisJ L Perez Castrillon
Internal Medicine Department, Rio Hortega University Hospital, Faculty of Medicine, Valladolid, Spain
Minerva Med 99:45-54. 2008..This review analyzes the clinical studies that support this association and describes the possible common etiopathogenic and physiopathological mechanisms...
Effect of atorvastatin on bone mineral density in patients with acute coronary syndromeJ L Perez-Castrillon
Department of Medicine, Rio Hortega University Hospital, Valladolid, Spain
Eur Rev Med Pharmacol Sci 12:83-8. 2008..The aim of this paper is to evaluate the effect of atorvastatin on bone mineral density in patients with acute ischemic heart disease...
Effect of the TNFalpha-308 G/A polymorphism on the changes produced by atorvastatin in bone mineral density in patients with acute coronary syndromeJosé Luis Pérez-Castrillón
Department of Internal Medicine, Rio Hortega University Hospital, Faculty of Medicine, Valladolid, Spain
Ann Nutr Metab 53:117-21. 2008..To evaluate the effect of atorvastatin on bone mass and markers of bone remodeling in patients with acute coronary syndrome depending on the tumor necrosis factor-alpha (TNFalpha)-308 G/A polymorphism...
Are beta-blockers useful in the prevention of osteoporotic fractures?J L Perez-Castrillon
Internal Medicine Department, Rio Hortega University Hospital, Faculty of Medicine, Valladolid, Spain
Eur Rev Med Pharmacol Sci 13:157-62. 2009..The aim of this paper is review these data and the possible role of beta-blockers in the prevention of osteoporotic fractures in patients with cardiovascular disease...
Effects of Atorvastatin on vitamin D levels in patients with acute ischemic heart diseaseJose L Perez-Castrillon
Internal Medicine Department, Rio Hortega University Hospital, Faculty of Medicine of Valladolid, Valladolid, Spain
Am J Cardiol 99:903-5. 2007..In conclusion, atorvastatin increases vitamin D levels. This increase could explain some of the beneficial effects of atorvastatin at the cardiovascular level that are unrelated to cholesterol levels...
Effect of angiotensin converting enzyme inhibitors on 1.25-(OH)2 D levels of hypertensive patients. Relationship with ACE polymorphismsJ L Perez-Castrillon
Departamento de Medicina Interna, Hospital Universitario Rio Hortega, Facultad de Medicina de Valladolid, Valladolid, Spain
Horm Metab Res 38:812-6. 2006..25-(OH)2D] levels has not been studied. The purpose of this study is to assess the relationship between 1.25-dihydroxyvitamin D levels and I/D angiotensin-converting enzyme polymorphism (ACE) in hypertensive patients...
Bone mass and bone modelling markers in hypertensive postmenopausal womenJ L Perez-Castrillon
Departamento Medicina Interna, Facultad de Medicina, Hospital Univcersitario Rió Hortega, Cardenal Torquemada s n, 47010 Valladolid, Spain
J Hum Hypertens 17:107-10. 2003..However, there was a negative osteocalcin correlation (r=-0.386, P=0.0001, and r=-0.242, P=0.033). Calciuria is associated with bone mass decrease in hypertensive women, and there is no relation between bone mass and blood pressure...
Relationship between bone mineral density and angiotensin converting enzyme polymorphism in hypertensive postmenopausal womenJosé Luis Pérez-Castrillón
Departamento Medicina Interna, Hospital Universitario Rio Hortega, Facultad de Medicina, Valladolid, Spain
Am J Hypertens 16:233-5. 2003..The purpose of this study was to assess the relationship between bone mineral density and insertion/deletion (I/D) angiotensin converting enzyme polymorphism (ACE) in hypertensive postmenopausal women...
[Bone mineral density in patients with multiple sclerosis: the effects of interferon]J L Perez Castrillon
Servicio de Medicina Interna, Hospital Universario Río Hortega, Valladolid, Espana
Rev Neurol 36:901-3. 2003..AIMS. Our aim was to evaluate the effect of interferon, a drug that has only recently been introduced in the treatment of the disease, on bone mineral density (BMD) and bone remodelling markers...
Effect of quinapril, quinapril-hydrochlorothiazide, and enalapril on the bone mass of hypertensive subjects: relationship with angiotensin converting enzyme polymorphismsJose L Perez-Castrillon
Departamento de Medicina Interna, Hospital Universitario Rio Hortega, Facultad de Medicina de Valladolid, Valladolid, Spain
Am J Hypertens 16:453-9. 2003....
Non-insulin-dependent diabetes, bone mineral density, and cardiovascular risk factorsJosé Luis Pérez-Castrillón
Department of Internal Medicine, Rio Hortega University Hospital, Cardenal Torquemada s n, 47010 Valladolid, Spain
J Diabetes Complications 18:317-21. 2004..The diabetic women had a higher BMD than the controls, and there was no relationship between osteoporosis and cardiovascular risk factors in diabetics...
Prevalence of osteoporosis using DXA bone mineral density measurements at the calcaneus: cut-off points of diagnosis and exclusion of osteoporosisJosé Luis Pérez-Castrillón
Servicio Medicina Internal Hospital Universitario Rio Hortega, Valladolid, Spain
J Clin Densitom 8:404-8. 2005..In women, a calcaneus T-score of >-1.0 enables the diagnosis of the disease to be excluded, whereas a calcaneus T-score of <-2.5 enables the diagnosis to be confirmed and treatment to be initiated in both men and women...
Calcium-sensing receptor gene A986S polymorphism and bone mass in hypertensive womenJosé Luis Pérez-Castrillón
Departamento de Medicina Interna, Facultad de Medicina, Hospital Universitario Rio Hortega, Valladolid, Spain
Arch Med Res 37:607-11. 2006..The objective was to assess the effect of CaSR gene A986S polymorphism on the lumbar spine bone mass, calcium metabolism parameters and markers of bone remodeling in hypertensive women...
Tularemia epidemic in northwestern Spain: clinical description and therapeutic responseJ L Perez-Castrillon
Department of Internal Medicine, Rio Hortega Hospital, University of Valladolid, Cardenal Torquemada s n, 47010 Valladolid, Spain
Clin Infect Dis 33:573-6. 2001..For 142 cases of tularemia, the therapeutic failure rate was 22.5%; ciprofloxacin was the antibiotic with the lowest percentage of therapeutic failures and with the fewest side effects...
Superior mesenteric venous thrombosis: a retrospective study of thirteen casesS Munoz
Service of Internal Medicine III, Hospital Clinico San Carlos, Madrid, Spain
Rev Esp Enferm Dig 96:385-90; 390-4. 2004..To analyze the epidemiology, associated risk factors, clinical presentation, diagnostic methods, treatment, and evolution of patients diagnosed with superior mesenteric venous thrombosis (SMVT) at an university hospital in Madrid...
Dietary protein restriction decreases oxidative protein damage, peroxidizability index, and mitochondrial complex I content in rat liverVictoria Ayala
Department of Basic Medical Sciences, Faculty of Medicine, University of Lleida, Spain
J Gerontol A Biol Sci Med Sci 62:352-60. 2007..Recent studies suggest that those benefits of PR could be caused, in turn, by the lowered methionine intake of that dietary manipulation...
Protein restriction without strong caloric restriction decreases mitochondrial oxygen radical production and oxidative DNA damage in rat liverAlberto Sanz
Department of Animal Physiology-II, Faculty of Biological Sciences, Complutense University, Madrid, 28040, Spain
J Bioenerg Biomembr 36:545-52. 2004..Interestingly, these tissue oxidative stress-linked parameters can be lowered by restricting only the intake of dietary protein, probably a more feasible option than caloric restriction for adult humans...
Evaluation of sex differences on mitochondrial bioenergetics and apoptosis in miceAlberto Sanz
Department of Animal Physiology II, Faculty of Biology, Complutense University, Madrid 28040, Spain
Exp Gerontol 42:173-82. 2007..These results support the Mitochondrial Free Radical Theory of Aging, and indicate that oxidative stress generation independent of estrogen levels determines aging rate...
