Manuel Romero-Gomez

Summary

Affiliation: Hospital Universitario de Valme
Country: Spain

Publications

  1. doi Gut ammonia production and its modulation
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Universidad de Sevilla, 41014 Sevilla, Spain
    Metab Brain Dis 24:147-57. 2009
  2. ncbi Role of phosphate-activated glutaminase in the pathogenesis of hepatic encephalopathy
    Manuel Romero-Gomez
    Hepatology Unit, Hospital Universitario de Valme, Sevilla, Spain
    Metab Brain Dis 20:319-25. 2005
  3. ncbi Acute hepatitis due to Mycoplasma pneumoniae infection without lung involvement in adult patients
    Manuel Romero-Gomez
    Digestive Diseases Unit, Hospital Universitario de Valme, Ctra Cádiz s n 41014, Sevilla, Spain
    J Hepatol 44:827-8. 2006
  4. ncbi Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis
    Manuel Romero-Gomez
    Unit for Clinical Management of Digestive Diseases, Hospital Universitario de Valme, ctra Cadiz s n, 41014 Seville, Spain
    World J Gastroenterol 12:2406-11. 2006
  5. ncbi [Normality tables in the Spanish population for psychometric tests used in the diagnosis of minimal hepatic encephalopathy]
    Manuel Romero Gomez
    Unidad de Gestión Clínica de Enfermedades Digestivas, Hospital Universitario de Valme, Sevilla, Spain
    Med Clin (Barc) 127:246-9. 2006
  6. ncbi Hepatitis C and insulin resistance: steatosis, fibrosis and non-response
    M Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases, Hospital Universitario de Valme, Seville, Spain
    Rev Esp Enferm Dig 98:605-15. 2006
  7. ncbi Insulin resistance and hepatitis C
    Manuel Romero-Gomez
    Unit for The Clinical Management of Digestive Diseases Hospital Universitario de Valme Ctra de Cadiz s n Sevilla 41014, Spain
    World J Gastroenterol 12:7075-80. 2006
  8. ncbi Value of the critical flicker frequency in patients with minimal hepatic encephalopathy
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases, Hospital Universitario de Valme, Sevilla, Spain
    Hepatology 45:879-85. 2007
  9. ncbi Optical analysis of computed tomography images of the liver predicts fibrosis stage and distribution in chronic hepatitis C
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Sevilla, Spain
    Hepatology 47:810-6. 2008
  10. doi Effect of sustained virological response to treatment on the incidence of abnormal glucose values in chronic hepatitis C
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Seville, Spain
    J Hepatol 48:721-7. 2008

Collaborators

Detail Information

Publications52

  1. doi Gut ammonia production and its modulation
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Universidad de Sevilla, 41014 Sevilla, Spain
    Metab Brain Dis 24:147-57. 2009
    ..Lastly, some genetic alterations in the glutaminase gene such as the haplotype TACC could modulate intestinal ammonia production and the risk of overt hepatic encephalopathy in cirrhotics...
  2. ncbi Role of phosphate-activated glutaminase in the pathogenesis of hepatic encephalopathy
    Manuel Romero-Gomez
    Hepatology Unit, Hospital Universitario de Valme, Sevilla, Spain
    Metab Brain Dis 20:319-25. 2005
    ..These data support an important role for intestinal and brain glutaminase in the pathogenesis of hepatic encephalopathy and could be a new target for future therapies...
  3. ncbi Acute hepatitis due to Mycoplasma pneumoniae infection without lung involvement in adult patients
    Manuel Romero-Gomez
    Digestive Diseases Unit, Hospital Universitario de Valme, Ctra Cádiz s n 41014, Sevilla, Spain
    J Hepatol 44:827-8. 2006
    ..Controversial data have been reported about the possibility of liver involvement with M. pneumoniae community-acquired pneumonia. We present two cases of acute hepatitis associated with M. pneumoniae infection without lung involvement...
  4. ncbi Phosphate-activated glutaminase activity is enhanced in brain, intestine and kidneys of rats following portacaval anastomosis
    Manuel Romero-Gomez
    Unit for Clinical Management of Digestive Diseases, Hospital Universitario de Valme, ctra Cadiz s n, 41014 Seville, Spain
    World J Gastroenterol 12:2406-11. 2006
    ....
  5. ncbi [Normality tables in the Spanish population for psychometric tests used in the diagnosis of minimal hepatic encephalopathy]
    Manuel Romero Gomez
    Unidad de Gestión Clínica de Enfermedades Digestivas, Hospital Universitario de Valme, Sevilla, Spain
    Med Clin (Barc) 127:246-9. 2006
    ..Psychometric Hepatic Encephalopathy Score (PHES) is a psychometric test battery widely utilized in the diagnosis of MHE which requires correction by age and education...
  6. ncbi Hepatitis C and insulin resistance: steatosis, fibrosis and non-response
    M Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases, Hospital Universitario de Valme, Seville, Spain
    Rev Esp Enferm Dig 98:605-15. 2006
    ..The treatment of insulin resistance by decreasing hyperinsulinemia could improve sustained response rates in patients with chronic hepatitis C treated with peginterferon plus ribavirin...
  7. ncbi Insulin resistance and hepatitis C
    Manuel Romero-Gomez
    Unit for The Clinical Management of Digestive Diseases Hospital Universitario de Valme Ctra de Cadiz s n Sevilla 41014, Spain
    World J Gastroenterol 12:7075-80. 2006
    ..In summary, hepatitis C promotes insulin resistance and insulin resistance induces interferon resistance, steatosis and fibrosis progression...
  8. ncbi Value of the critical flicker frequency in patients with minimal hepatic encephalopathy
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases, Hospital Universitario de Valme, Sevilla, Spain
    Hepatology 45:879-85. 2007
    ..In multivariate analysis using Cox regression, CFF together with Child-Pugh score was independently associated with the development of overt HE...
  9. ncbi Optical analysis of computed tomography images of the liver predicts fibrosis stage and distribution in chronic hepatitis C
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Sevilla, Spain
    Hepatology 47:810-6. 2008
    ..86, 95%CI: 0.80 to 0.93. The correlation between Fibro-CT and fibrosis was higher in patients with homogeneous distribution of fibrosis than in patients with heterogeneous distribution (r = 0.77 versus r = 0.43; P < 0.05)...
  10. doi Effect of sustained virological response to treatment on the incidence of abnormal glucose values in chronic hepatitis C
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Seville, Spain
    J Hepatol 48:721-7. 2008
    ..To investigate the effect of sustained virological response (SVR) on impaired fasting glucose (IFG) and/or type 2 diabetes (T2DM); to assess the influence of glucose abnormalities on the SVR rate...
  11. ncbi [Hepatitis C: cryoglobulinemia and non-Hodgkin lymphoma]
    M Romero-Gomez
    Unidad de Gestión Clínica de Enfermedades Digestivas, Hospital Universitario de Valme, Carretera de Cádiz s n, Seville
    Rev Esp Enferm Dig 100:164-70. 2008
    ..Therefore, in chronic hepatitis C, the combination of peginterferon + ribavirin is strongly recommended in treating symptomatic mixed cryoglobulinemia and HCV-related non-Hodgkin lymphomas...
  12. ncbi [Comparative study of two models that use biochemical parameters for the non-invasive diagnosis of fibrosis in patients with hepatitis C]
    Manuel Romero Gomez
    Unidad de Hepatologia, Hospital Universitario de Valme, Sevilla, Espana
    Med Clin (Barc) 124:761-4. 2005
    ..Our study was aimed to compare both non-invasive methods to predict mild fibrosis (F0-F1) or to confirm advanced fibrosis (F3, F4) in patients with chronic hepatitis C...
  13. ncbi Altered response to oral glutamine challenge as prognostic factor for overt episodes in patients with minimal hepatic encephalopathy
    Manuel Romero-Gomez
    Unit of Hepatology, Hospital Universitario de Valme, Ctra Cádiz s n 41014 Seville, Spain
    J Hepatol 37:781-7. 2002
    ..We assessed the usefulness of oral glutamine challenge (OGC) and minimal hepatic encephalopathy in evaluating risk of overt hepatic encephalopathy in cirrhotic patients...
  14. ncbi Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients
    Manuel Romero-Gomez
    Hepatology Unit, Hospital Universitario de Valme, Sevilla, Spain
    Gastroenterology 128:636-41. 2005
    ..We evaluated the effect of insulin resistance and viral factors on sustained virological response in patients with chronic hepatitis C treated with peginterferon plus ribavirin...
  15. ncbi Three-day intravenous triple therapy is not effective for the eradication of Helicobacter pylori infection in patients with bleeding gastro-duodenal ulcer
    M Romero-Gomez
    Digestive and Hepatology Unit, Hospital Universitario de Valme, Seville, Spain
    Aliment Pharmacol Ther 18:1023-9. 2003
    ..To test the efficacy of an ultra-short intravenous triple therapy against Helicobacter pylori infection in patients with bleeding peptic ulcer against standard oral 1-week triple therapy in a randomised, double-blind prospective trial...
  16. pmc SLC11A1 promoter gene polymorphisms and fibrosis progression in chronic hepatitis C
    M Romero-Gomez
    Hepatology Unit, Hospital Universitario de Valme, Sevilla, Spain
    Gut 53:446-50. 2004
    ..We investigated the possible role of the functional polymorphism located in the promoter region of SLC11A1 and tumour necrosis factor (TNF) genes in the progression of fibrosis in chronic hepatitis C...
  17. ncbi Intestinal glutaminase activity is increased in liver cirrhosis and correlates with minimal hepatic encephalopathy
    Manuel Romero-Gomez
    Hepatology Unit, Hospital Universitario de Valme, ctra Cadiz s n, 41014 Sevilla, Spain
    J Hepatol 41:49-54. 2004
    ..We performed the current study to assess the intestinal activity of enterocyte phosphate-activated glutaminase (PAG) in cirrhosis...
  18. ncbi [New concepts in the physiopathology of hepatic encephalopathy and therapeutic prospects]
    M Romero Gomez
    Unidad de Hepatologia, Hospital Universitario de Valme, Ctra Cádiz, S N, 41014 Sevilla, Espana
    Gastroenterol Hepatol 27:40-8. 2004
  19. doi Treatment of insulin resistance with metformin in naïve genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Hospital Universitario de Valme, Sevilla, Spain
    Hepatology 50:1702-8. 2009
    ..88 (1.18) versus -4.0 (1.44) (P = 0.021), whereas no differences were seen in males. The triple therapy was well tolerated, but diarrhea was more often seen in arm A (34% versus 11%; P < 0.05)...
  20. ncbi HLA class I B44 is associated with sustained response to interferon + ribavirin therapy in patients with chronic hepatitis C
    Manuel Romero-Gomez
    Hepatology Unit, Hospital Universitario de Valme, Seville, Spain
    Am J Gastroenterol 98:1621-6. 2003
    ..The aim of this study was to assess the influence of host genetic factors on response to combination therapy for chronic hepatitis C infection...
  21. ncbi Serum leptin levels correlate with hepatic steatosis in chronic hepatitis C
    Manuel Romero-Gomez
    Units of Hepatology, Hospital Universitario de Valme, Sevilla, Spain
    Am J Gastroenterol 98:1135-41. 2003
    ..Hepatic steatosis (HS) has been related to obesity and fibrosis in chronic hepatitis C (CHC). The aim of this study was to determine the role of leptin system in HS development...
  22. ncbi Predicting portal hypertension and variceal bleeding using non-invasive measurements of metabolic variables
    Mohammed Eslam
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Sevilla, Spain
    Ann Hepatol 12:588-98. 2013
    ..This study assessed the involvement of metabolic factors (anthropometric indices, insulin resistance (IR) and adipocytokines) in the prediction of portal hypertension, esophageal varices and risk of variceal bleeding in cirrhotic patients...
  23. pmc Metformin inhibits glutaminase activity and protects against hepatic encephalopathy
    Javier Ampuero
    Unit for Clinical Management of Digestive Diseases and CIBERehd, Hospital Universitario de Valme, University of Sevilla, Sevilla, Spain
    PLoS ONE 7:e49279. 2012
    ..To analyze the impact of metformin on glutaminase activity and ammonia production in vitro...
  24. ncbi Incidence of and factors associated with hepatocellular carcinoma among hepatitis C virus and human immunodeficiency virus coinfected patients with decompensated cirrhosis
    José A García-García
    Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital Universitario de Valme, Sevilla, Spain
    AIDS Res Hum Retroviruses 22:1236-41. 2006
    ..This is probably due to the fact that HIV infection shortens the survival of HCV-coinfected patients with end-stage liver disease to such an extent that HCC not had a chance to emerge...
  25. doi Insulin resistance impairs viral dynamics independently of ethnicity or genotypes
    Mohammed Eslam
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Ctra de Cadiz s n, Sevilla, Spain
    J Clin Gastroenterol 46:228-34. 2012
    ..Data concerning the influence of insulin resistance (IR) and ethnicity on early phases of viral kinetics after initiation of peginterferon plus ribavirin in treatment-naive, chronic hepatitis C (CHC) patients are limited...
  26. doi Interleukin-28B genetic variants and hepatitis virus infection by different viral genotypes
    Marco Antonio Montes-Cano
    Servicio de Inmunologia, Hospital Universitario Virgen del Rocio Instituto de Biomedicina de Sevilla, Sevilla, Spain
    Hepatology 52:33-7. 2010
    ..2 x 10(-5), OR = 0.32; 95%CI, 0.18-0.57); and lastly, patients with sustained response (60.2% versus 32.1% found in patients with nonsustained response, P = 3.1 x 10(-5), OR = 0.31; 95%CI, 0.17-0.56)...
  27. ncbi Prognostic value of altered oral glutamine challenge in patients with minimal hepatic encephalopathy
    Manuel Romero-Gomez
    Unit of Hepatology, Hospital Universitario de Valme, Seville, Spain
    Hepatology 39:939-43. 2004
    ..In conclusion, a pathological OGC response in patients with MHE appears to be associated with lower survival rate and may prove useful in the selection of candidates for liver transplantation...
  28. pmc HAVCR1 gene haplotypes and infection by different viral hepatitis C virus genotypes
    Cristina Abad-Molina
    Servicio de Inmunologia, Hospital Universitario Virgen del Rocío Instituto de Biomedicina, Sevilla, Spain
    Clin Vaccine Immunol 19:223-7. 2012
    ..72%, respectively; corrected P value [P(c)], 3.2 × 10(-4); odds ratio [OR], 2.30; 95% confidence interval [CI], 1.51 to 3.47). Thus, HAVCR1 could be involved in susceptibility or resistance to infection by a particular HCV genotype...
  29. doi Insulin resistance and response to antiviral therapy in chronic hepatitis C: mechanisms and management
    Jose A Del Campo
    Unit for Clinical Management of Digestive Diseases and CIBERehd, Valme University Hospital, Seville, Spain
    Dig Dis 28:285-93. 2010
    ..Insulin resistance is a new target in the challenging management of chronic hepatitis C...
  30. doi Role of diabetes mellitus on hepatic encephalopathy
    Javier Ampuero
    Unit for Clinical Management of Digestive Diseases and CIBERehd, Hospital Universitario de Valme, University of Sevilla, Avenida de Bellavista S N, Sevilla 41014, Spain
    Metab Brain Dis 28:277-9. 2013
    ....
  31. ncbi Tumour necrosis factor alpha polymorphisms are not involved in the development of steatosis in chronic hepatitis C
    Diego Sanchez-Munoz
    Hepatology Unit, Hospital Universitario de Valme, Seville, Spain
    Eur J Gastroenterol Hepatol 16:761-5. 2004
    ..To determine whether the different tumour necrosis factor alpha (TNF-alpha) promoter gene polymorphisms are involved in the development of steatosis in chronic hepatitis C...
  32. doi Variations in the promoter region of the glutaminase gene and the development of hepatic encephalopathy in patients with cirrhosis: a cohort study
    Manuel Romero-Gomez
    Hospital Universitario de Valme, Universidad de Sevilla, Spain
    Ann Intern Med 153:281-8. 2010
    ..Hepatic encephalopathy is a major complication of cirrhosis and is associated with a poor prognosis...
  33. pmc The hepatitis C virus modulates insulin signaling pathway in vitro promoting insulin resistance
    Jose A Del Campo
    Unit for Medical and Surgical Management of Digestive Diseases and CIBERehd, Valme University Hospital, Sevilla, Spain
    PLoS ONE 7:e47904. 2012
    ..A strong effect of HCV infection on insulin pathway-related gene and protein expression was found in vitro. These results could lead to the identification of new therapeutic targets in HCV infection and its co-morbidities...
  34. doi The role of insulin resistance in HIV/hepatitis C virus-coinfected patients
    Mohammed Eslam
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Ctra de Cadiz s n, Spain
    Curr Opin HIV AIDS 6:553-8. 2011
    ..The objective of this review was to explore the meaning of insulin resistance in HIV-HCV-coinfected patients and how it may impact on sustained virological response (SVR) and disease progression...
  35. doi Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment
    Manuel Romero-Gomez
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Sevilla, Spain
    Liver Int 31:443-60. 2011
    ..However, nearly half of patients achieving SVR did not show favourable genotype. Further genetic signals are warranted to complete the puzzle of factors influencing hepatitis C...
  36. pmc HLA alleles influence the clinical signature of amoxicillin-clavulanate hepatotoxicity
    Camilla Stephens
    Unidad de Gestión Clínica de Enfermedades Digestivas, Servicio de Farmacologia Clinica, Hospital Universitario Virgen de la Victoria, Instituto de Investigación Biomédica de Málaga Ibima, Universidad de Malaga, Malaga, Spain
    PLoS ONE 8:e68111. 2013
    ..In this study we aimed to examine potential associations between HLA class I and II alleles and AC DILI with regards to phenotypic characteristics, severity and time to onset in Spanish AC hepatotoxicity cases...
  37. ncbi Serum immunological profile in patients with chronic autoimmune cholestasis
    Manuel Romero-Gomez
    Unidad de Hepatologia, Hospital Universitario de Valme, Sevilla, Spain
    Am J Gastroenterol 99:2150-7. 2004
    ..To compare patients who had biochemical and histological features of chronic autoimmune cholestasis (CAIC) using serological autoantibody profiling...
  38. ncbi Histologic features of steatohepatitis in patients with a clinical diagnosis of autoimmune cholestasis
    Diego Sanchez-Munoz
    Hospital Universitario de Valme, Sevilla, Spain
    Dig Dis Sci 49:1957-61. 2004
  39. pmc Steatosis and insulin resistance in hepatitis C: a way out for the virus?
    Jose A Del Campo
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Ctra de Cadiz s n, Sevilla 41014, Spain
    World J Gastroenterol 15:5014-9. 2009
    ..Steatosis and insulin resistance have been associated with fibrosis progression and a reduced rate of sustained response to peginterferon plus ribavirin...
  40. doi Pharmacotherapy of hepatic encephalopathy in cirrhosis
    Manuel Romero-Gomez
    Unit for Clinical Management of Digestive Diseases and CIBERehd, Hospital Universitario de Valme, University of Seville, Seville, Spain
    Expert Opin Pharmacother 11:1317-27. 2010
    ..Hepatic encephalopathy (HE) is a major complication encountered in nearly half of the patients with liver cirrhosis...
  41. ncbi HIV coinfection shortens the survival of patients with hepatitis C virus-related decompensated cirrhosis
    Juan A Pineda
    Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital Universitario de Valme, 41014 Sevilla, Spain
    Hepatology 41:779-89. 2005
    ..This fact must be taken into account to establish the adequate timing of liver transplantation in HIV-coinfected subjects...
  42. doi [Hepatitis C and metabolic syndrome]
    Reyes Aparcero López
    Unidad de Gestión Clínica de Enfermedades Digestivas, Hospital Universitario de Valme, Sevilla, Espana
    Gastroenterol Hepatol 33:530-40. 2010
    ..The TRIC-1 study demonstrated that adding metformin to routine treatment improves the possibilities of cure in women and in patients whose insulin sensitivity returns to normal during treatment...
  43. doi Serum selenium levels and oxidative balance as differential markers in hepatic damage caused by alcohol
    Rui M Rua
    Department of Physiology, Faculty of Pharmacy, Seville University, Seville, Spain
    Life Sci 94:158-63. 2014
    ..This study examines the effects of chronic ethanol consumption on oxidative balance, including selenium (Se) levels in alcoholic patients with or without liver disease, and if these measurements could be indicative of liver disease...
  44. ncbi Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry
    Raul J Andrade
    Unidad de Hepatologia, Grupo de Estudio para las Hepatopatías Asociadas a Medicamentos, Co ordinating Centre, Hospital Universitario Virgen de la Victoria, Facultad de Medicina, Campus Universitario de Teatinos s n, Malaga, Spain
    Hepatology 44:1581-8. 2006
    ..Cardiovascular and central nervous system drugs are the main groups leading to chronic liver damage...
  45. doi Predictive factors for erythema nodosum and pyoderma gangrenosum in inflammatory bowel disease
    Javier Ampuero
    Unit for Clinical Management of Digestive Diseases, Valme University Hospital, Sevilla, Spain
    J Gastroenterol Hepatol 29:291-5. 2014
    ..To identify predictive factors related to the development of erythema nodosum and pyoderma gangrenosum, in patients with inflammatory bowel disease (IBD)...
  46. doi [Influence of non-alcoholic fatty liver disease on cardiovascular disease]
    Javier Ampuero
    Unidad de Gestión Clínica de Enfermedades Digestivas, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Hospital Universitario de Valme, Universidad de Sevilla, Sevilla, Espana
    Gastroenterol Hepatol 35:585-93. 2012
    ..Therefore, the correct management of non-alcoholic fatty liver disease would allow the natural history of both the liver disease and the atherosclerosis to be modified...
  47. ncbi HLA-C and KIR genes in hepatitis C virus infection
    Marco Antonio Montes-Cano
    Servicio de Inmunologia, Hospital Universitario Virgen del Rocio, Sevilla, Spain
    Hum Immunol 66:1106-9. 2005
    ..02, OR = 1.68, 95% CI = 1.07-2.65). Trends toward lower frequencies of the HLA-C2C2 genotype and NK-HLA interactions with strong and moderate affinity among the patients with persistent infection were also observed...
  48. doi Brain biomolecules oxidation in portacaval-shunted rats
    Pilar Carbonero-Aguilar
    Departamento de Bioquimica y Biologia Molecular, Facultad de Farmacia, Universidad de Sevilla, Sevilla, Spain
    Liver Int 31:964-9. 2011
    ..Therefore, oxidative damage of brain biomolecules could contribute towards explaining the neurological and motor alterations observed in HE...
  49. doi [Alcoholic and non-alcoholic steatohepatitis: who is affected and what can we do for them?]
    Rocío Gallego-Durán
    Unidad Médico Quirúrgica de Enfermedades Digestivas y CIBERehd, Hospital Universitario de Valme, Universidad de Sevilla, Sevilla, Espana
    Gastroenterol Hepatol 36:587-96. 2013
    ..The first-line treatment consists of lifestyle changes, including giving up alcohol, diet and exercise. ..
  50. doi Cutaneous lymphoma in a patient with ulcerative colitis after immunosuppressive therapy
    Maria Rojas-Feria
    Unit for the Clinical Management of Digestive Diseases and CIBEREHD, Hospital Universitario de Valme, Ctra de Cadiz s n, Sevilla 41014, Spain
    J Crohns Colitis 5:608-11. 2011
    ..Biologics are generally safe and well tolerated. However, the risk of haematopoietic cancer in patients with inflammatory bowel disease receiving infliximab has been a growing concern...
  51. doi Propranolol-induced angioedema in a patient with chronic hepatitis C virus infection
    Esther Márquez-Saavedra
    Andalusian Health Service, Seville, Spain
    Am J Health Syst Pharm 67:1182-4. 2010
    ..A case of angioedema secondary to propranolol therapy in a patient with chronic hepatitis C virus (HCV) infection is reported...
  52. doi [Virological response to adefovir dipivoxil predicts the long-term development of resistance in previously untreated patients with HBeAg-negative chronic hepatitis B]
    Emilio Suarez
    Unidad de Gestión Clínica de Enfermedades Digestivas, Hospital Universitario Virgen de Valme, Sevilla, Espana
    Gastroenterol Hepatol 34:69-74. 2011
    ..The aims of this study were to assess the efficacy of adefovir dipivoxil treatment in naïve and lamivudine-resistant patients and to determine whether virological response predicts the development of adefovir resistance...