Nuria Ribas-Fito

..Newborns are exposed across the placenta and through breast feeding. Experimental animal studies have indicated that PCBs are neurotoxic. The neurological effects of these compounds on children are not clear...

..These results should be considered when evaluating the risk and benefits of spraying DDT during antimalaria and other disease-vector campaigns...

..Design Prospective cohort study. Participants 1,712 children born between 1959 and 1966 with measured p,p'-DDE concentrations in their mother's serum samples from pregnancy. Setting Multicenter US Collaborative Perinatal Project (CPP)...

..Hexachlorobenzene (HCB) is an organochlorine chemical that has been used in agriculture and industrial processes. Behavioral impairment after HCB exposure has been described in animal models, but little information is available in humans...

..26 among breast feeders, and 1.95 of p,p'-DDE vs 6.00 (P<0.05)). Long-term breastfeeding leads to a dose-response increase of the concentrations in children's serum during the first year of life...

..In contrast, concentrations of polychlorinated biphenyls (PCB) in the period 1997-1999 showed a nonsignificant increase compared with those in 1994...

..30 (standard error, 0.12) per week breastfed). Despite the possibility of harm from environmental contaminants in breast milk, breastfeeding for long periods should still be recommended as the best infant feeding method...

..To determine whether prenatal exposure to hexachlorobenzene (HCB) has potential adverse effects on child's weight and body mass index (BMI) in a general population with no local pollution sources...

..Pregnant women are being assessed at 12, 20 and 32 weeks of gestation to collect information about environmental exposures and fetal growth. The children will be followed until the age of 4 years...

..We studied the association between exposure to OCs and breastfeeding on neurodevelopment in the 1-year-old infants of this population...

..However, these results should be taken with caution because the differences of the gender averages have low statistically significance when evaluated with the Student test...

..We aimed at analysing the association of individual urinary porphyrins with the serum concentrations of HCB and other organochlorine compounds in this highly exposed population...

..DDE was not associated with atopy alone. Prenatal exposure to DDE residues may contribute to development of asthma...

..This influence is reflected in higher exposure, both in utero and in the first years of growth, that significantly stands out over the background contamination due to the ubiquity of these compounds...

..The observed increases of average body burden of total PBDEs between birth and the first 4 years of growth were 65 and 10 ng for breastfed and formula fed children, respectively...

..The results did not vary when stratified for prematurity. These data suggest that HCB reduces intrauterine physical linear growth...

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..In both populations, the results showed that a major proportion of the organochlorine compounds present in these children's serum at 4 years of age was incorporated during the lactation period...

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..We assess which behavioural areas (executive function, social competence, attention behaviour and hyperactivity) are related to long-term breast-feeding in young children...

..Reported folic acid supplement use during pregnancy was associated with improved neurodevelopment in children after adjusting for a number of sociodemographic and behavioural factors...

..We hypothesized that genetic variability in glutathione S-transferase (GST) genes (GSTP1, GSTM1, and GSTT1) could influence the effects of prenatal exposure to p,p'-DDT...

..Evidence in humans, however, is contradictory. In neonates and adults from a population historically highly exposed to HCB (Flix, Catalonia, Spain), no relation with PCT or with porphyrin excretion was found...

..The aim of this study was to evaluate iodine status and to examine the main sources of iodine in pregnant women from an apparently iodine-sufficient area...

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..To date, only one study has examined whether smoking in the first trimester only, which is not associated with birth weight, is also associated with childhood overweight...

..Results of this review show how such studies may be developed and used...

..The actual magnitude of human contamination by PTS and their trends across Spain -as well as the geographic and social heterogeneity- remain largely unknown...

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..Within the framework of a follow-up study in pregnant women, we describe: 1) the personal habits of water use and consumption, and 2) trihalomethane levels in the drinking water of the study areas...