Jordi Rello

Summary

Affiliation: Hospital Universitari Germans Trias i Pujol
Country: Spain

Publications

  1. ncbi request reprint Oral care practices in intensive care units: a survey of 59 European ICUs
    Jordi Rello
    Joan XXIII University Hospital, Critical Care Department, Mallafre Guasch 4, 43007 Tarragona, Spain
    Intensive Care Med 33:1066-70. 2007
  2. ncbi request reprint Reduced burden of bacterial airway colonization with a novel silver-coated endotracheal tube in a randomized multiple-center feasibility study
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Crit Care Med 34:2766-72. 2006
  3. ncbi request reprint De-escalation therapy in ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Tarragona, Spain
    Crit Care Med 32:2183-90. 2004
  4. doi request reprint Why mortality is increased in health-care-associated pneumonia: lessons from pneumococcal bacteremic pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Carrer Mallafre Guasch, 4, Tarragona 43007, Spain
    Chest 137:1138-44. 2010
  5. doi request reprint PIRO score for community-acquired pneumonia: a new prediction rule for assessment of severity in intensive care unit patients with community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Crit Care Med 37:456-62. 2009
  6. doi request reprint First influenza season after the 2009 pandemic influenza: report of the first 300 ICU admissions in Spain
    A Rodriguez
    Hospital Joan XXIII, Critical Care Department, IISPV, URV, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Med Intensiva 35:208-16. 2011
  7. ncbi request reprint Risk factors for ventilator-associated pneumonia by Pseudomonas aeruginosa in presence of recent antibiotic exposure
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Anesthesiology 105:709-14. 2006
  8. doi request reprint Radiologic progression of pulmonary infiltrates predicts a worse prognosis in severe community-acquired pneumonia than bacteremia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, CIBER Enfermedades Respiratorias, Carrer Mallafre Guasch, Tarragona, Spain
    Chest 135:165-72. 2009
  9. ncbi request reprint [Infection associated with the use of assisted-ventilation devices]
    Emili Diaz
    Servicio Medicina Intensiva, Hospital Universitari Joan XXIII, Tarragona, Spain
    Enferm Infecc Microbiol Clin 26:465-70. 2008
  10. doi request reprint Severe pandemic (H1N1)v influenza A infection: report on the first deaths in Spain
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, Spain
    Respirology 16:78-85. 2011

Detail Information

Publications90

  1. ncbi request reprint Oral care practices in intensive care units: a survey of 59 European ICUs
    Jordi Rello
    Joan XXIII University Hospital, Critical Care Department, Mallafre Guasch 4, 43007 Tarragona, Spain
    Intensive Care Med 33:1066-70. 2007
    ..To explore the type and frequency of oral care practices in European ICUs and the attitudes, beliefs, and knowledge of health care workers...
  2. ncbi request reprint Reduced burden of bacterial airway colonization with a novel silver-coated endotracheal tube in a randomized multiple-center feasibility study
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Crit Care Med 34:2766-72. 2006
    ..To assess the feasibility and safety of the respiratory infection control (RIC) device, a silver-coated endotracheal tube, and its effect on bacterial burden in the airways...
  3. ncbi request reprint De-escalation therapy in ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Tarragona, Spain
    Crit Care Med 32:2183-90. 2004
    ..To evaluate de-escalation of antibiotic therapy in patients with ventilator-associated pneumonia...
  4. doi request reprint Why mortality is increased in health-care-associated pneumonia: lessons from pneumococcal bacteremic pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Carrer Mallafre Guasch, 4, Tarragona 43007, Spain
    Chest 137:1138-44. 2010
    ..A cohort of patients with bacteremic Streptococcus pneumoniae pneumonia was reviewed to assess why mortality is higher in health-care-associated pneumonia (HCAP) than in community-acquired pneumonia (CAP)...
  5. doi request reprint PIRO score for community-acquired pneumonia: a new prediction rule for assessment of severity in intensive care unit patients with community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Crit Care Med 37:456-62. 2009
    ....
  6. doi request reprint First influenza season after the 2009 pandemic influenza: report of the first 300 ICU admissions in Spain
    A Rodriguez
    Hospital Joan XXIII, Critical Care Department, IISPV, URV, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Med Intensiva 35:208-16. 2011
    ..During the 2009 influenza pandemic, several reports were published, nevertheless, data on the clinical profiles of critically ill patients with the new virus infection during this second outbreak are still lacking...
  7. ncbi request reprint Risk factors for ventilator-associated pneumonia by Pseudomonas aeruginosa in presence of recent antibiotic exposure
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Anesthesiology 105:709-14. 2006
    ....
  8. doi request reprint Radiologic progression of pulmonary infiltrates predicts a worse prognosis in severe community-acquired pneumonia than bacteremia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, CIBER Enfermedades Respiratorias, Carrer Mallafre Guasch, Tarragona, Spain
    Chest 135:165-72. 2009
    ..The objective of this study was to investigate the relative importance of these two factors in the outcome of patients with severe CAP (sCAP)...
  9. ncbi request reprint [Infection associated with the use of assisted-ventilation devices]
    Emili Diaz
    Servicio Medicina Intensiva, Hospital Universitari Joan XXIII, Tarragona, Spain
    Enferm Infecc Microbiol Clin 26:465-70. 2008
    ....
  10. doi request reprint Severe pandemic (H1N1)v influenza A infection: report on the first deaths in Spain
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, Spain
    Respirology 16:78-85. 2011
    ..The impact of pandemic influenza A (H1N1)v infection is still unknown but it is associated with a high case-fatality rate...
  11. doi request reprint The ventilator-associated pneumonia PIRO score: a tool for predicting ICU mortality and health-care resources use in ventilator-associated pneumonia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 134:1208-16. 2008
    ..No score is available to assess severity and stratify mortality risk in ventilator-associated pneumonia (VAP). Our objective was to develop a severity assessment tool for VAP patients...
  12. doi request reprint Elevation of creatine kinase is associated with worse outcomes in 2009 pH1N1 influenza A infection
    Bárbara Borgatta
    Critical Care Department, Vall d Hebron University Hospital, Universitat Autonoma de Barcelona UAB, 08035, Barcelona, Spain
    Intensive Care Med 38:1152-61. 2012
    ..Current medical knowledge lacks specific information regarding creatine kinase (CK) elevation in influenza A pH1N1 (2009) infection...
  13. doi request reprint A randomized trial of dental brushing for preventing ventilator-associated pneumonia
    Angel Pobo
    Critical Care Department, Joan XXIII University Hospital, 43007 Tarragona, Spain
    Chest 136:433-9. 2009
    ..Poor oral hygiene is associated with respiratory pathogen colonization and secondary lung infection. The impact of adding electric toothbrushing to oral care in order to reduce ventilator-associated pneumonia (VAP) incidence is unknown...
  14. ncbi request reprint Impact of diversity of antibiotic use on the development of antimicrobial resistance
    Alberto Sandiumenge
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili Institut Pere Virgili, Tarragona 43007, Spain
    J Antimicrob Chemother 57:1197-204. 2006
    ..To evaluate the impact of different antibiotic strategies on acquisition of resistant microorganisms...
  15. ncbi request reprint Management of ventilator-associated pneumonia in a multidisciplinary intensive care unit: does trauma make a difference?
    Kemal Agbaht
    CIBER Enfermedades Respiratorias, University of Rovira and Virgili, Critical Care Department, Joan XXIII University Hospital, Institut Pere Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Intensive Care Med 33:1387-95. 2007
    ..Antibiotic exposure and timing of pneumonia onset influence ventilator-associated pneumonia (VAP) isolates. The first goal of this investigation was to evaluate whether trauma also influences prevalence of microorganisms...
  16. pmc Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study
    Monica Magret
    Critical Care Department, Vall d Hebron University Hospital, CibeRes, VHIR, Universitat Autonoma de Barcelona, Vall d Hebron St, Barcelona 08035, Spain
    Crit Care 15:R62. 2011
    ..The purpose of the study is to compare risk factors, pathogens and outcomes between bacteremic nosocomial pneumonia (B-NP) and nonbacteremic nosocomial pneumonia (NB-NP) episodes...
  17. pmc Acute kidney injury in critical ill patients affected by influenza A (H1N1) virus infection
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital CIBER Enfermedades Respiratorias, URV, and IISPV, Mallafre i Guasch, ES 43007 Tarragona, Spain
    Crit Care 15:R66. 2011
    ..Little information exists about the impact of acute kidney injury (AKI) in critically ill patients with the pandemic 2009 influenza A (H1N1) virus infection...
  18. ncbi request reprint Clinical resolution in patients with suspicion of ventilator-associated pneumonia: a cohort study comparing patients with and without acute respiratory distress syndrome
    Loreto Vidaur
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Tarragona, Spain
    Crit Care Med 33:1248-53. 2005
    ..A secondary objective was to identify clinical variables that might be useful for monitoring response to therapy...
  19. doi request reprint Mortality and regional oxygen saturation index in septic shock patients: a pilot study
    Alejandro Rodriguez
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias, Tarragona, Spain
    J Trauma 70:1145-52. 2011
    ....
  20. ncbi request reprint Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia
    Kemal Agbaht
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care Med 35:2064-70. 2007
    ..To assess whether bacteremic ventilator-associated pneumonia (B-VAP) differs in terms of risk factors, organisms, and outcomes from nonbacteremic VAP (NB-VAP)...
  21. doi request reprint Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough
    Alejandro Rodriguez
    Critical Care Department, Pere Virgili Health Institut and CIBER Enfermedades Respiratorias, Joan XXIII University Hospital, Tarragona, Spain
    Intensive Care Med 35:430-8. 2009
    ..It remains uncertain why immunocompetent patients with bacterial community-acquired pneumonia (CAP) die, in spite of adequate antibiotics...
  22. ncbi request reprint Nursing adherence with evidence-based guidelines for preventing ventilator-associated pneumonia
    Maite Ricart
    Critical Care Department, Joan XXIII University Hospital, Universitat Rovira i Virgili, Tarragona, Spain
    Crit Care Med 31:2693-6. 2003
    ..To review barriers to nursing adherence to nonpharmacologic evidence-based guidelines for preventing ventilator-associated pneumonia...
  23. ncbi request reprint Pneumonia caused by oxacillin-resistant Staphylococcus aureus treated with glycopeptides
    Jordi Rello
    Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care Med 33:1983-7. 2005
    ..To determine whether ventilator-associated pneumonia caused by oxacillin-resistant Staphylococcus aureus (VAP-ORSA) treated with glycopeptides is associated with an increased mortality rate...
  24. doi request reprint Impact of nonexacerbated COPD on mortality in critically ill patients
    Alejandro Rodriguez
    Critical Care Department, Joan XXIII University Hospital, CIBERes Enfermedades Respiratorias, Universidad Rovira i Virgili IISPV, Tarragona, Spain
    Chest 139:1354-60. 2011
    ..The real contribution of nonexacerbated COPD to mortality has not been studied. The aim of our study was to evaluate the impact of nonexacerbated COPD on mortality in patients requiring mechanical ventilation (MV)...
  25. ncbi request reprint Hospital-acquired pneumonia in the 21st century: a review of existing treatment options and their impact on patient care
    Despoina Koulenti
    Critical Care Department, Joan XXIII University Hospital Institut Pere Virgili, Mallafre Guasch, 4, 43007 Tarragona, Spain
    Expert Opin Pharmacother 7:1555-69. 2006
    ..The optimal duration of treatment is a matter of debate, but courses longer than 1 week are rarely justified...
  26. doi request reprint Ventilator-associated pneumonia: impact of organisms on clinical resolution and medical resources utilization
    Loreto Vidaur
    Critical Care Department, Joan XXIII University Hospital and Pere Virgili Health Institute, Tarragona, Spain
    Chest 133:625-32. 2008
    ..The aim of this study was to evaluate the influence of organisms and their susceptibility to treatment on outcomes...
  27. ncbi request reprint Incidence, etiology, and outcome of nosocomial pneumonia in ICU patients requiring percutaneous tracheotomy for mechanical ventilation
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 124:2239-43. 2003
    ..To determine the epidemiology of pneumonia in patients with tracheotomy receiving short-term mechanical ventilation...
  28. doi request reprint Impact of early oseltamivir treatment on outcome in critically ill patients with 2009 pandemic influenza A
    Alejandro Rodriguez
    Hospital Joan XXIII, Critical Care Department IISPV URV CIBERES, Tarragona, Spain
    J Antimicrob Chemother 66:1140-9. 2011
    ..The main objective of this study was to investigate the relationship between the timing of antiviral administration and intensive care unit (ICU) outcomes...
  29. ncbi request reprint Risk factors for pneumonia in the intubated patient
    Olga Diaz
    Critical Care Department, Hospital Doce de Octubre, Madrid, Spain
    Infect Dis Clin North Am 17:697-705. 2003
    ..This variable should be considered when stratifying patients for risk factor analysis and also in the design of clinical trials for VAP prophylaxis...
  30. doi request reprint Corticosteroid therapy in patients with primary viral pneumonia due to pandemic (H1N1) 2009 influenza
    Emili Diaz
    Critical Care Department, Hospital Sant Joan Despí Moisès Broggi, Jacint Verdaguer, 90, 08970 Sant Joan Despí, Barcelona, CibeRes, IISPV, Spain
    J Infect 64:311-8. 2012
    ..The objective of this study was to assess the effect on survival of corticosteroid therapy in patients with pandemic (H1N1) 2009 influenza...
  31. ncbi request reprint Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock
    Alejandro Rodriguez
    Intensive Care Unit, Joan XXIII University Hospital, Tarragona, Spain
    Crit Care Med 35:1493-8. 2007
    ..To assess whether combination antibiotic therapy improves outcome of severe community-acquired pneumonia in the subset of patients with shock...
  32. ncbi request reprint Management of ventilator-associated pneumonia caused by multiresistant bacteria
    Emili Diaz
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili Institut Pere Virgili, Tarragona Spain
    Curr Opin Crit Care 13:45-50. 2007
    ..The inappropriate choice of antibiotics (in nearly one third of episodes) is the most important risk factor for death. Traditionally, a narrow-spectrum drug was used first, and the most potent drugs were reserved for subsequent use...
  33. ncbi request reprint Clinical approach to the patient with suspected ventilator-associated pneumonia
    Loreto Vidaur
    Critical Care Department, University Rovira and Virgili Institut Pere Virgili, Joan XXIII University Hospital, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Respir Care 50:965-74; discussion 974. 2005
    ..Optimal management should be based on a strategy combining early high doses of an effective agent for a short period of time, which is then simplified in the light of microbiologic information...
  34. doi request reprint Ventilator-associated pneumonia in trauma patients is associated with lower mortality: results from EU-VAP study
    M Magret
    Critical Care Department, Sant Joan University Hospital, Reus, Spain
    J Trauma 69:849-54. 2010
    ..Differences in trauma patients developing ventilator-associated pneumonia (VAP) are described regarding etiology and risk factors associated. We aim to describe the differences in outcomes in trauma and nontrauma patients with VAP...
  35. doi request reprint Impact of obesity in patients infected with 2009 influenza A(H1N1)
    Emili Diaz
    Critical Care Department, Hospital Universitario Joan XXIII CIBER Enfermedades Respiratorias, URV, and IISPV, Carrer Dr, Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 139:382-6. 2011
    ..However, its role remains unclear. We evaluate the outcome of patients who are obese and infected with A(H1N1) in the ICU, determining whether obesity is a risk factor for mortality...
  36. ncbi request reprint Pneumonia in the intensive care unit
    Jordi Rello
    Critical Care Department, Joan XXII University Hospital, University Rovira i Virgili, Taragona, Spain
    Crit Care Med 31:2544-51. 2003
    ..To update the state-of-the-art on pneumonia in adult patients in the intensive care unit (ICU), with special emphasis on new developments in management...
  37. ncbi request reprint C-reactive protein correlates with bacterial load and appropriate antibiotic therapy in suspected ventilator-associated pneumonia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Crit Care Med 36:166-71. 2008
    ....
  38. ncbi request reprint Therapy of ventilator-associated pneumonia. A patient-based approach based on the ten rules of "The Tarragona Strategy"
    Alberto Sandiumenge
    Department of Critical Care, Joan XXIII University Hospital, University Rovira and Virgili, C Doctor Mallafré Guasch, 4, 43007, Tarragona, Spain
    Intensive Care Med 29:876-83. 2003
    ..The choice of initial antibiotic should be based on the patient's previous antibiotic exposure and comorbidities, and local antibiotic susceptibility patterns, which should be updated regularly...
  39. ncbi request reprint Nosocomial lung infections in adult intensive care units
    Gonzalo Hernandez
    Critical Care Department, 12, de Octubre University Hospital, University Complutense, Madrid, Spain
    Microbes Infect 6:1004-14. 2004
    ..Nosocomial pneumonias are often difficult to treat due to antibiotic-resistant bacteria. Antibiotic policies are crucial in avoiding a progression in antibiotic resistance...
  40. doi request reprint PAI-1 gene: pharmacogenetic association of 4G/4G genotype with bleeding after cardiac surgery--pilot study
    Gonzalo Sirgo
    Intensive Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Pere Virgili Health Institute, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Eur J Anaesthesiol 26:404-11. 2009
    ..To investigate whether the 4G/4G genotype of the PAI-1 gene is associated with bleeding after cardiac surgery and whether it may influence the use of antifibrinolytic drugs...
  41. doi request reprint New treatment options for infections caused by multiresistant strains of Pseudomonas aeruginosa and other nonfermenting gram-negative bacilli
    Anna Sanchez
    Critical Care Department, Vall d Hebron University Hospital, Barcelona, Spain
    Semin Respir Crit Care Med 32:151-8. 2011
    ..Future options include immunotherapy or the continuous infusion of antibiotics. It is also important to emphasize the rational use of antibiotics to diminish the appearance of multiresistant pathogens...
  42. doi request reprint Effect of antibiotic diversity on ventilator-associated pneumonia caused by ESKAPE Organisms
    Alberto Sandiumenge
    Critical Care Department, Joan XXIII University Hospital, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 140:643-51. 2011
    ....
  43. doi request reprint Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection
    I Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias CIBERES, Tarragona, Spain
    Intensive Care Med 37:272-83. 2011
    ..Early use of corticosteroids in patients affected by pandemic (H1N1)v influenza A infection, although relatively common, remains controversial...
  44. pmc Bench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care 9:259-65. 2005
    ..More active, less toxic antibacterial agents are still needed, in particular to combat problematic pathogens such as multiresistant Gram-negative bacilli and resistant Gram-positive organisms (e.g. methicillin-resistant S aureus)...
  45. ncbi request reprint Epidemiology and outcomes of ventilator-associated pneumonia in a large US database
    Jordi Rello
    University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Chest 122:2115-21. 2002
    ..To evaluate risk factors for ventilator-associated pneumonia (VAP), as well as its influence on in-hospital mortality, resource utilization, and hospital charges...
  46. ncbi request reprint Etiology of ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Carrer Dr Mallafre Guasch 4, Tarragona 43007, Spain
    Clin Chest Med 26:87-95. 2005
    ..The discussion herein analyzes these aspects, placing particular emphasis on risk factors, attributable mortality, resistance, and the implications for management...
  47. pmc Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, CIBERes Enfermedades Respiratorias, IISPV, Mallafre Guasch 4, 43007 Tarragona, Spain
    Crit Care 13:R148. 2009
    ..We describe the clinical and epidemiologic characteristics of the first 32 persons reported to be admitted to the intensive care unit (ICU) due to influenza A (H1N1)v infection in Spain...
  48. ncbi request reprint Ventilator-associated pneumonia: issues related to the artificial airway
    Emili Diaz
    Critical Care Department, University Rovira and Virgili Institut Pere Virgili, Joan XXIII University Hospital, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Respir Care 50:900-6; discussion 906-9. 2005
    ..As many studies suggest that incidence of VAP is highly dependent on the strategies of airway management, health care workers should be alerted to issues related to the artificial airway...
  49. doi request reprint Activity of a silver-coated endotracheal tube in preclinical models of ventilator-associated pneumonia and a study after extubation
    Jordi Rello
    Joan XXIII University Hospital, CIBER Enfermedades Respiratorias CIBERES, University Rovira i Virgili, IISPV, Tarragona, Spain
    Crit Care Med 38:1135-40. 2010
    ..To elucidate the mechanism of action of the silver-coated endotracheal tube in models of the early pathogenesis of ventilator-associated pneumonia...
  50. doi request reprint Diagnosis of ventilator-associated pneumonia: is there a gold standard and a simple approach?
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Curr Opin Infect Dis 21:174-8. 2008
    ..Recent findings in diagnosis are reviewed here...
  51. ncbi request reprint Prevention of infection in the intensive care unit: current advances and opportunities for the future
    Carmen Lorente
    Critical Care Department, University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Curr Opin Crit Care 8:461-4. 2002
    ..Potential measures of control should focus on the patient, the microorganisms, and the device. A number of recent studies addressing these issues have been published and will be reviewed in this article...
  52. doi request reprint Community-acquired respiratory coinfection in critically ill patients with pandemic 2009 influenza A(H1N1) virus
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, CibeRes, Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 139:555-62. 2011
    ..Little is known about the impact of community-acquired respiratory coinfection in patients with pandemic 2009 influenza A(H1N1) virus infection...
  53. doi request reprint Management of ventilator-associated pneumonia
    Emili Diaz
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias, Carrer Mallafre Guasch 4, Tarragona 43007, Spain
    Infect Dis Clin North Am 23:521-33. 2009
    ..In recent years, a more dynamic approach has evolved, updating local epidemiology, evaluating VAP and diagnostic tools every day, and assessing host response using clinical and biochemical parameters...
  54. ncbi request reprint Effects of high-dose of intravenous immunoglobulin and antibiotics on survival for severe sepsis undergoing surgery
    Alejandro Rodriguez
    Intensive Care Department of Joan XXIII University Hospital University Rovira and Virgili and Institut Pere Virgili, Tarragona, Spain
    Shock 23:298-304. 2005
    ..We conclude that IVIG administration, when used in combination with adequate antibiotics, improved the survival of surgical ICU patients with intra-abdominal sepsis. The initial choice of antibiotic has a dramatic impact on outcome...
  55. doi request reprint A European care bundle for management of ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Vall d Hebron University Hospital, Institut de Recerca Vall d Hebron Universitat Autònoma de Barcelona, CIBER Enfermedades Respiratorias CIBERES, Barcelona, Spain
    J Crit Care 26:3-10. 2011
    ..Although there is a wealth of guidance concerning the management of patients with ventilator-associated pneumonia (VAP), compliance with recommendations concerning optimal treatment practices is highly variable...
  56. pmc Demographics, guidelines, and clinical experience in severe community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital University Rovira i Virgili, Pere Virgili Health Institut, CIBER Enfermedades Respiratorias CIBERES, Tarragona 43007, Spain
    Crit Care 12:S2. 2008
    ....
  57. doi request reprint Effect of high-flow nasal cannula and body position on end-expiratory lung volume: a cohort study using electrical impedance tomography
    Jordi Riera
    Critical Care Department, Vall d Hebron Research Institut, Vall d Hebron University Hospital, Universitat Autonoma de Barcelona, Barcelona, Spain
    Respir Care 58:589-96. 2013
    ..We used electrical impedance tomography to investigate the effects of high-flow nasal cannula (HFNC) and body position on global and regional end-expiratory lung impedance variation (ΔEELI)...
  58. pmc The simple and the simpler in pneumonia diagnosis
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBERes Enfermedades Respiratorias, Carrer Mallafre Guasch, 4 43007, Tarragona, Spain
    Crit Care 11:140. 2007
    ....
  59. doi request reprint Appropriateness is critical
    Marta Ulldemolins
    Critical Care Department, Vall d Hebron University Hospital, Passeig de la Vall d Hebron, 119 129, 08035 Barcelona, Spain
    Crit Care Clin 27:35-51. 2011
    ..Consideration of issues beyond in vitro susceptibility, such as antibiotic physicochemistry, tissue penetration, and pharmacokinetic/pharmacodynamic-driven dosing, is mandatory for the optimization of antibiotic use...
  60. ncbi request reprint Microbiological testing and outcome of patients with severe community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 123:174-80. 2003
    ..The study documents the impact of microbiological investigations on therapeutic decisions and outcome in patients with severe community-acquired pneumonia (SCAP)...
  61. ncbi request reprint Association between 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene with stroke or encephalopathy after cardiac surgery
    Gonzalo Sirgo
    Intensive Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Mallafre Guasch N 4, 43007, Tarragona, Spain
    Intensive Care Med 32:668-75. 2006
    ....
  62. doi request reprint Severity of pneumococcal pneumonia associated with genomic bacterial load
    Jordi Rello
    Critical Care Department, Hospital Universitari Joan XXIII, 43007 Tarragona, Spain
    Chest 136:832-40. 2009
    ..As viral load is useful in viral infections, we hypothesized that bacterial load may be associated with outcomes in patients with pneumococcal pneumonia...
  63. doi request reprint [Pharmacologic measures for the prevention of mechanical ventilation-associated pneumonia]
    Marta Ulldemolins
    Servicio de Medicina Intensiva, Hospital Universitario de Tarragona Joan XXIII, Instituto de Investigación Sanitaria Pere Virgili IISPV, Tarragona, Spain
    Med Clin (Barc) 136:21-5. 2011
    ..The aim of this review is to critically describe the principal pharmacologic interventions for the prevention of ventilator associated pneumonia, focusing on the degree of the evidence and the appropriateness for daily clinical practice...
  64. ncbi request reprint Gram-negative bacterial pneumonia: aetiology and management
    Despoina Koulenti
    Critical Care Department, Joan XXIII University Hospital, University Rovira y Virgili Institut PereVirgili, Tarragona, Spain
    Curr Opin Pulm Med 12:198-204. 2006
    ..Recent articles of clinical and investigational interest on Gram-negative pneumonia, particularly hospital-acquired and ventilator-associated pneumonia, are reviewed...
  65. ncbi request reprint Top ten list in antibiotic policy in the ICU
    Emili Diaz
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 122:712-4. 2002
  66. ncbi request reprint Why do physicians not follow evidence-based guidelines for preventing ventilator-associated pneumonia?: a survey based on the opinions of an international panel of intensivists
    Jordi Rello
    Critical Care Department, University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Chest 122:656-61. 2002
    ..Adherence to clinical practice guidelines is highly variable. Our objective was to review barriers to physicians' adherence to evidence-based guidelines (EBGs) for preventing ventilator-associated pneumonia (VAP)...
  67. ncbi request reprint Impact of antibiotic guideline compliance on duration of mechanical ventilation in critically ill patients with community-acquired pneumonia
    Andrew F Shorr
    Pulmonary and Critical Care Section, Department of Medicine, Room 2A 38D, Washington Hospital Center, Washington, DC 20010, USA
    Chest 130:93-100. 2006
    ..Our goal was to assess the impact of following these guidelines, such as those from the Infectious Disease Society of America (IDSA), on the duration of mechanical ventilation (MV)...
  68. ncbi request reprint Clinical impact of pneumonia caused by Acinetobacter baumannii in intubated patients: a matched cohort study
    Jose Garnacho
    Hospital Universitario Virgen del Rocio, Seville, Spain
    Crit Care Med 31:2478-82. 2003
    ..To determine whether ventilator-associated pneumonia caused by Acinetobacter baumannii (VAPAB) is associated with increased mortality rate...
  69. ncbi request reprint Prevention and diagnosis of ventilator-associated pneumonia: a survey on current practices in Southern Spanish ICUs
    Rafael Sierra
    Intensive Care Unit, Puerta del Mar University Hospital, University of Cadiz, Spain
    Chest 128:1667-73. 2005
    ..To assess the implementation of selected ventilator-associated pneumonia (VAP) prevention strategies, and to learn how VAP is diagnosed in the ICUs of Southern Spain...
  70. ncbi request reprint A 7-year study of severe hospital-acquired pneumonia requiring ICU admission
    Jordi Valles
    Critical Care Center, Hospital Sabadell, Institut Universitari Parc Tauli Universitat Autónoma de Barcelona, Parc Tauli s n, 08208, Barcelona, Spain
    Intensive Care Med 29:1981-8. 2003
    ..To examine the characteristics, prognostic factors, and outcome of patients with severe hospital-acquired pneumonia admitted to the ICU...
  71. ncbi request reprint Patterns of colonization by Pseudomonas aeruginosa in intubated patients: a 3-year prospective study of 1,607 isolates using pulsed-field gel electrophoresis with implications for prevention of ventilator-associated pneumonia
    Jordi Valles
    Critical Care Center, Hospital Sabadell and UDIAT Diagnostic Center, Institut Universitari, Universitat Autonoma Barcelona, Parc Tauli s n, 08208 Sabadell, Spain
    Intensive Care Med 30:1768-75. 2004
    ..To identify routes and patterns of colonization with Pseudomonas aeruginosa in intubated patients to design strategies of prevention for respiratory infection...
  72. ncbi request reprint Acinetobacter baumannii: a threat for the ICU?
    Jordi Rello
    Intensive Care Med 29:350-1. 2003
  73. ncbi request reprint [Cyclic rotation of antibiotics. Is all that glitters gold?]
    Alberto Sandiumenge
    Servicio de Cuidados Intensivos Hospital Universitario Joan XXIII Universitat Rovira i Virgili Tarragona España
    Enferm Infecc Microbiol Clin 21:93-100. 2003
    ..In this article several methodological considerations are suggested for future studies testing this new antibiotic strategy...
  74. ncbi request reprint Effect of enriched thioglycolate on direct examination of respiratory specimens and guiding initial empirical therapy in intubated patients with pneumonia: a prospective, randomized study
    Jordi Rello
    Intensive Care Department, Hospital de Sabadell, Sabadell, Barcelona, Spain
    Crit Care Med 30:311-4. 2002
    ..To evaluate the use of enriched thioglycolate as a transport medium of protected specimen brush samples, in particular its value in direct examination of respiratory specimens and in guiding initial antibiotic prescription...
  75. ncbi request reprint Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa
    Alan R Hauser
    Department of Microbiology Immunology, Northwestern University, Chicago, IL, USA
    Crit Care Med 30:521-8. 2002
    ..The objective of this study was to determine whether this system contributes to disease severity in humans with ventilator-associated pneumonia...
  76. ncbi request reprint Changing physicians' behavior in the intensive care unit
    Jordi Rello
    Crit Care Med 30:2593-4. 2002
  77. ncbi request reprint Community-acquired bloodstream infection in critically ill adult patients: impact of shock and inappropriate antibiotic therapy on survival
    Jordi Valles
    Intensive Care Department, Hospital de Sabadell, Spain
    Chest 123:1615-24. 2003
    ....
  78. ncbi request reprint Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia
    Richard G Wunderink
    Methodist Healthcare Memphis and the University of Tennessee, Memphis, TN 38104 3499, USA
    Chest 124:1789-97. 2003
    ..To assess the effect of baseline variables, including treatment, on outcome in patients with nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus (MRSA)...
  79. ncbi request reprint Secretion of the toxin ExoU is a marker for highly virulent Pseudomonas aeruginosa isolates obtained from patients with hospital-acquired pneumonia
    Grant S Schulert
    Department of Microbiology Immunology, Northwestern University, Chicago, Illinois 60611, USA
    J Infect Dis 188:1695-706. 2003
    ..Together, these findings suggest that secretion of ExoU is a marker for highly virulent strains of P. aeruginosa...
  80. ncbi request reprint Optimal management therapy for Pseudomonas aeruginosa ventilator-associated pneumonia: an observational, multicenter study comparing monotherapy with combination antibiotic therapy
    Jose Garnacho-Montero
    Critical Care and Emergency Department, Hospital Universitario Virgen del Rocio, Sevilla, Spain
    Crit Care Med 35:1888-95. 2007
    ..To evaluate whether one antibiotic achieves equal outcomes compared with combination antibiotic therapy in patients with Pseudomonas aeruginosa ventilator-associated pneumonia...
  81. ncbi request reprint Optimal therapy for methicillin-resistant Staphylococcus aureus pneumonia: what is the best dosing regimen?
    Jordi Rello
    Chest 130:938-40. 2006
  82. ncbi request reprint [Clinical approach to the patient with ventilator-associated pneumonia]
    Loreto Vidaur
    Servicio de Medicina Intensiva, Hospital Universitario Joan XXIII, Tarragona, Espana
    Enferm Infecc Microbiol Clin 23:18-23. 2005
    ..Recent studies suggest that shorter antibiotic regimens reduce the emergence of antibiotic-resistant pathogens, cost and adverse events...
  83. ncbi request reprint [Nosocomial pneumonia: local response to a global problem]
    Jordi Rello
    Servicio de Medicina Intensiva, Hospital Universitario Joan XXIII, Tarragona, Espana
    Enferm Infecc Microbiol Clin 23:1. 2005
  84. ncbi request reprint Optimal therapy for severe pneumococcal community-acquired pneumonia
    Manel Lujan
    Pulmonary Service, Corporació Parc Taulí Institut Universitari Parc Taulí, Sabadell, Spain
    Intensive Care Med 32:971-80. 2006
    ..Prospective, randomized clinical trials of pneumonia patients with a pneumonia severity index score above 90 are warranted to define optimal antibiotic regimens...
  85. ncbi request reprint Influence of renal function on the pharmacokinetics of piperacillin/tazobactam in intensive care unit patients during continuous venovenous hemofiltration
    Alazne Arzuaga
    Laboratorio de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Paseo de la Universidad no 7, 01006 Vitoria Gasteiz, Spain
    J Clin Pharmacol 45:168-76. 2005
    ..The extracorporeal clearance of piperacillin/tazobactam is clinically significant in patients with CL(CR) > 50 mL/min, in which the risk of underdosing and clinical failure is important and extra doses are required...
  86. ncbi request reprint Benefits of minocycline and rifampin-impregnated central venous catheters. A prospective, randomized, double-blind, controlled, multicenter trial
    Cristóbal León
    Intensive Care Unit, Hospital Universitario de Valme, Universidad de Sevilla, Carretera de Cádiz s n, 41014 Sevilla, Spain
    Intensive Care Med 30:1891-9. 2004
    ..To determine the efficacy of minocycline and rifampin-impregnated catheters compared to non-impregnated catheters in critically ill patients...
  87. ncbi request reprint Antibiotic use and the risk of pneumonia: 20 years of studies, but where are we now?
    Emili Diaz
    Clin Infect Dis 38:1409-11. 2004
  88. ncbi request reprint Prospective observational study of bacteremic pneumococcal pneumonia: Effect of discordant therapy on mortality
    Manel Lujan
    Pulmonary Department, Corporacio Parc Tauli, Sabadell, Barcelona, Spain
    Crit Care Med 32:625-31. 2004
    ..To evaluate the effect of discordant empirical therapy on outcome in bacteremic pneumococcal community-acquired pneumonia...
  89. ncbi request reprint Clinical cure and survival in Gram-positive ventilator-associated pneumonia: retrospective analysis of two double-blind studies comparing linezolid with vancomycin
    Marin H Kollef
    Pulmonary and Critical Care Division, Department of Internal Medicine, School of Medicine, Washington University, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Intensive Care Med 30:388-94. 2004
    ..To assess the effect of baseline variables, including treatment, on clinical cure and survival rates in patients with Gram-positive, ventilator-associated pneumonia (VAP)...
  90. ncbi request reprint Severity of illness assessment for managing community-acquired pneumonia
    Jordi Rello
    Intensive Care Med 33:2043-4. 2007