J Rello

Summary

Affiliation: Hospital Universitari de Tarragona Joan XXIII
Country: Spain

Publications

  1. ncbi Ventilator-associated pneumonia: impact of organisms on clinical resolution and medical resources utilization
    Loreto Vidaur
    Critical Care Department, Joan XXIII University Hospital and Pere Virgili Health Institute, Tarragona, Spain
    Chest 133:625-32. 2008
  2. ncbi Therapy of ventilator-associated pneumonia. A patient-based approach based on the ten rules of "The Tarragona Strategy"
    Alberto Sandiumenge
    Department of Critical Care, Joan XXIII University Hospital, University Rovira and Virgili, C Doctor Mallafré Guasch, 4, 43007, Tarragona, Spain
    Intensive Care Med 29:876-83. 2003
  3. ncbi Pharmacokinetics, pharmacodynamics, safety and tolerability of tigecycline
    J Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    J Chemother 17:12-22. 2005
  4. ncbi Incidence, etiology, and outcome of nosocomial pneumonia in ICU patients requiring percutaneous tracheotomy for mechanical ventilation
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 124:2239-43. 2003
  5. ncbi Microbiological testing and outcome of patients with severe community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 123:174-80. 2003
  6. ncbi [Nosocomial pneumonia: local response to a global problem]
    Jordi Rello
    Servicio de Medicina Intensiva, Hospital Universitario Joan XXIII, Tarragona,
    Enferm Infecc Microbiol Clin 23:1. 2005
  7. ncbi Etiology of ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Carrer Dr Mallafre Guasch 4, Tarragona 43007, Spain
    Clin Chest Med 26:87-95. 2005
  8. ncbi Why do physicians not follow evidence-based guidelines for preventing ventilator-associated pneumonia?: a survey based on the opinions of an international panel of intensivists
    Jordi Rello
    Critical Care Department, University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Chest 122:656-61. 2002
  9. ncbi Advances in the management of pneumonia in the intensive care unit: review of current thinking
    J Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Tarragona, Spain
    Clin Microbiol Infect 11:30-8. 2005
  10. ncbi Bench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care 9:259-65. 2005

Detail Information

Publications99

  1. ncbi Ventilator-associated pneumonia: impact of organisms on clinical resolution and medical resources utilization
    Loreto Vidaur
    Critical Care Department, Joan XXIII University Hospital and Pere Virgili Health Institute, Tarragona, Spain
    Chest 133:625-32. 2008
    ..The aim of this study was to evaluate the influence of organisms and their susceptibility to treatment on outcomes...
  2. ncbi Therapy of ventilator-associated pneumonia. A patient-based approach based on the ten rules of "The Tarragona Strategy"
    Alberto Sandiumenge
    Department of Critical Care, Joan XXIII University Hospital, University Rovira and Virgili, C Doctor Mallafré Guasch, 4, 43007, Tarragona, Spain
    Intensive Care Med 29:876-83. 2003
    ..The choice of initial antibiotic should be based on the patient's previous antibiotic exposure and comorbidities, and local antibiotic susceptibility patterns, which should be updated regularly...
  3. ncbi Pharmacokinetics, pharmacodynamics, safety and tolerability of tigecycline
    J Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    J Chemother 17:12-22. 2005
    ..C. difficile-related complications with tigecycline are uncommon. In the majority of patients, tigecycline has minimal adverse effects on blood chemistry or haematology...
  4. ncbi Incidence, etiology, and outcome of nosocomial pneumonia in ICU patients requiring percutaneous tracheotomy for mechanical ventilation
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 124:2239-43. 2003
    ..To determine the epidemiology of pneumonia in patients with tracheotomy receiving short-term mechanical ventilation...
  5. ncbi Microbiological testing and outcome of patients with severe community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 123:174-80. 2003
    ..The study documents the impact of microbiological investigations on therapeutic decisions and outcome in patients with severe community-acquired pneumonia (SCAP)...
  6. ncbi [Nosocomial pneumonia: local response to a global problem]
    Jordi Rello
    Servicio de Medicina Intensiva, Hospital Universitario Joan XXIII, Tarragona,
    Enferm Infecc Microbiol Clin 23:1. 2005
  7. ncbi Etiology of ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Carrer Dr Mallafre Guasch 4, Tarragona 43007, Spain
    Clin Chest Med 26:87-95. 2005
    ..The discussion herein analyzes these aspects, placing particular emphasis on risk factors, attributable mortality, resistance, and the implications for management...
  8. ncbi Why do physicians not follow evidence-based guidelines for preventing ventilator-associated pneumonia?: a survey based on the opinions of an international panel of intensivists
    Jordi Rello
    Critical Care Department, University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Chest 122:656-61. 2002
    ..Adherence to clinical practice guidelines is highly variable. Our objective was to review barriers to physicians' adherence to evidence-based guidelines (EBGs) for preventing ventilator-associated pneumonia (VAP)...
  9. ncbi Advances in the management of pneumonia in the intensive care unit: review of current thinking
    J Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Tarragona, Spain
    Clin Microbiol Infect 11:30-8. 2005
    ..Therefore, antibiotic choice should be institution-specific and patient-oriented...
  10. ncbi Bench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care 9:259-65. 2005
    ..More active, less toxic antibacterial agents are still needed, in particular to combat problematic pathogens such as multiresistant Gram-negative bacilli and resistant Gram-positive organisms (e.g. methicillin-resistant S aureus)...
  11. ncbi Implications of COPD in patients admitted to the intensive care unit by community-acquired pneumonia
    J Rello
    Critical Care Dept, Joan XXIII University Hospital, Carrer Mallafre Guasch 4, E43007 Tarragona, Spain
    Eur Respir J 27:1210-6. 2006
    ....
  12. ncbi De-escalation therapy in ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Tarragona, Spain
    Crit Care Med 32:2183-90. 2004
    ..The impact of quantitative tracheal aspirates or bronchoscopic techniques was comparable in terms of mortality...
  13. ncbi A randomized trial of dental brushing for preventing ventilator-associated pneumonia
    Angel Pobo
    Critical Care Department, Joan XXIII University Hospital, 43007 Tarragona, Spain
    Chest 136:433-9. 2009
    ..Poor oral hygiene is associated with respiratory pathogen colonization and secondary lung infection. The impact of adding electric toothbrushing to oral care in order to reduce ventilator-associated pneumonia (VAP) incidence is unknown...
  14. ncbi Antibacterial treatment of invasive mechanical ventilation-associated pneumonia
    F Barcenilla
    Servicio de Medicina Intensiva, Hospital Universitario Arnau de Vilanova, Lleida, Spain
    Drugs Aging 18:189-200. 2001
    ..However, the choice of the antibacterial regimen should follow local guidelines of treatment based upon the knowledge of the most frequently isolated bacterial flora and their susceptibilities in different clinical settings...
  15. ncbi First influenza season after the 2009 pandemic influenza: report of the first 300 ICU admissions in Spain
    A Rodriguez
    Hospital Joan XXIII, Critical Care Department, IISPV, URV, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Med Intensiva 35:208-16. 2011
    ..MATERIAL METHODS: Prospective, observational, multi-center study conducted in 148 Spanish intensive care units (ICU) during epidemiological weeks 50-52 of 2010 and weeks 1 - 4 of 2011...
  16. ncbi Associations between empirical antimicrobial therapy at the hospital and mortality in patients with severe community-acquired pneumonia
    J Rello
    Critical Care Department, University Hospital Joan XXIII, Mallafre Guasch 4, 43007 Tarragona
    Intensive Care Med 28:1030-5. 2002
    ..The aim of the study was to examine different antibiotic choices and their relation to outcomes...
  17. ncbi Antibiotic prescription for community-acquired pneumonia in the intensive care unit: impact of adherence to Infectious Diseases Society of America guidelines on survival
    M Bodi
    Intensive Care Dept, Joan XXIII University Hospital, Tarragona, Spain
    Clin Infect Dis 41:1709-16. 2005
    ..The purpose of our study was to analyze prognostic factors associated with mortality for patients with severe community-acquired pneumonia (CAP)...
  18. ncbi Determinants of prescription and choice of empirical therapy for hospital-acquired and ventilator-associated pneumonia
    J Rello
    Critical Care Department, Vall d Hebron University Hospital, Vall d Hebron Institut de Recerca, Universitat Autonoma de Barcelona, Passeig de la Vall d Hebron, 119 129, 08035, Barcelona, Spain
    Eur Respir J 37:1332-9. 2011
    ..Across Europe, carbapenems were the antibiotic most prescribed for HAP/VAP...
  19. ncbi International Conference for the Development of Consensus on the Diagnosis and Treatment of Ventilator-associated Pneumonia
    J Rello
    Hospital Universitari Joan XXIII, Tarragona, Spain
    Chest 120:955-70. 2001
    ..Consensus was reached on the importance of local epidemiology surveillance programs and on the need for customized empiric antimicrobial choices to respond to local patterns of pathogens and susceptibilities...
  20. ncbi Why mortality is increased in health-care-associated pneumonia: lessons from pneumococcal bacteremic pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Carrer Mallafre Guasch, 4, Tarragona 43007, Spain
    Chest 137:1138-44. 2010
    ..A cohort of patients with bacteremic Streptococcus pneumoniae pneumonia was reviewed to assess why mortality is higher in health-care-associated pneumonia (HCAP) than in community-acquired pneumonia (CAP)...
  21. ncbi [Infection associated with the use of assisted-ventilation devices]
    Emili Diaz
    Servicio Medicina Intensiva, Hospital Universitari Joan XXIII, Tarragona, Spain
    Enferm Infecc Microbiol Clin 26:465-70. 2008
    ....
  22. ncbi Impact of Gram-positive resistance on outcome of nosocomial pneumonia
    M Bodi
    Department of Critical Care, Hospital Universitari Joan XXIII, University Rovira i Virgili, Tarragona, Spain
    Crit Care Med 29:N82-6. 2001
    ..Optimizing treatment focusing on this goal and new antimicrobials provide new opportunities to improve survival. (Crit Care Med 2001; 29[Suppl.]:N82-N86)..
  23. ncbi [Clinical approach to the patient with ventilator-associated pneumonia]
    Loreto Vidaur
    Servicio de Medicina Intensiva, Hospital Universitario Joan XXIII, Tarragona,
    Enferm Infecc Microbiol Clin 23:18-23. 2005
    ..Recent studies suggest that shorter antibiotic regimens reduce the emergence of antibiotic-resistant pathogens, cost and adverse events...
  24. ncbi Elevation of creatine kinase is associated with worse outcomes in 2009 pH1N1 influenza A infection
    Bárbara Borgatta
    Critical Care Department, Vall d Hebron University Hospital, Universitat Autonoma de Barcelona UAB, 08035, Barcelona, Spain
    Intensive Care Med 38:1152-61. 2012
    ..Current medical knowledge lacks specific information regarding creatine kinase (CK) elevation in influenza A pH1N1 (2009) infection...
  25. ncbi Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection
    I Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias CIBERES, Tarragona, Spain
    Intensive Care Med 37:272-83. 2011
    ..Early use of corticosteroids in patients affected by pandemic (H1N1)v influenza A infection, although relatively common, remains controversial...
  26. ncbi Pneumonia in the intensive care unit
    Jordi Rello
    Critical Care Department, Joan XXII University Hospital, University Rovira i Virgili, Taragona, Spain
    Crit Care Med 31:2544-51. 2003
    ..To update the state-of-the-art on pneumonia in adult patients in the intensive care unit (ICU), with special emphasis on new developments in management...
  27. ncbi PIRO score for community-acquired pneumonia: a new prediction rule for assessment of severity in intensive care unit patients with community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Crit Care Med 37:456-62. 2009
    ....
  28. ncbi Nosocomial lung infections in adult intensive care units
    Gonzalo Hernandez
    Critical Care Department, 12, de Octubre University Hospital, University Complutense, Madrid, Spain
    Microbes Infect 6:1004-14. 2004
    ..Nosocomial pneumonias are often difficult to treat due to antibiotic-resistant bacteria. Antibiotic policies are crucial in avoiding a progression in antibiotic resistance...
  29. ncbi Pneumonia caused by oxacillin-resistant Staphylococcus aureus treated with glycopeptides
    Jordi Rello
    Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care Med 33:1983-7. 2005
    ..75 days) days for controls (p = .054). CONCLUSIONS: Despite appropriate glycopeptide therapy, there is an increased attributable mortality for pneumonia by ORSA, after careful adjustment for disease severity and diagnostic category...
  30. ncbi Impact of diversity of antibiotic use on the development of antimicrobial resistance
    Alberto Sandiumenge
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili Institut Pere Virgili, Tarragona 43007, Spain
    J Antimicrob Chemother 57:1197-204. 2006
    ..To evaluate the impact of different antibiotic strategies on acquisition of resistant microorganisms...
  31. ncbi Risk factors for pneumonia in the intubated patient
    Olga Diaz
    Critical Care Department, Hospital Doce de Octubre, Madrid, Spain
    Infect Dis Clin North Am 17:697-705. 2003
    ..This variable should be considered when stratifying patients for risk factor analysis and also in the design of clinical trials for VAP prophylaxis...
  32. ncbi Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough
    Alejandro Rodriguez
    Critical Care Department, Pere Virgili Health Institut and CIBER Enfermedades Respiratorias, Joan XXIII University Hospital, Tarragona, Spain
    Intensive Care Med 35:430-8. 2009
    ..It remains uncertain why immunocompetent patients with bacterial community-acquired pneumonia (CAP) die, in spite of adequate antibiotics...
  33. ncbi Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock
    Alejandro Rodriguez
    Intensive Care Unit, Joan XXIII University Hospital, Tarragona, Spain
    Crit Care Med 35:1493-8. 2007
    ..To assess whether combination antibiotic therapy improves outcome of severe community-acquired pneumonia in the subset of patients with shock...
  34. ncbi Hospital-acquired pneumonia in the 21st century: a review of existing treatment options and their impact on patient care
    Despoina Koulenti
    Critical Care Department, Joan XXIII University Hospital Institut Pere Virgili, Mallafre Guasch, 4, 43007 Tarragona, Spain
    Expert Opin Pharmacother 7:1555-69. 2006
    ..The optimal duration of treatment is a matter of debate, but courses longer than 1 week are rarely justified...
  35. ncbi Nursing adherence with evidence-based guidelines for preventing ventilator-associated pneumonia
    Maite Ricart
    Critical Care Department, Joan XXIII University Hospital, Universitat Rovira i Virgili, Tarragona, Spain
    Crit Care Med 31:2693-6. 2003
    ..Our findings suggest the need for development of multinational guidelines to reduce variability and the need to include the nursing point of view in these guidelines...
  36. ncbi Risk factors for ventilator-associated pneumonia by Pseudomonas aeruginosa in presence of recent antibiotic exposure
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Anesthesiology 105:709-14. 2006
    ....
  37. ncbi First influenza season after the 2009 pandemic influenza: characteristics of intensive care unit admissions in adults and children in Vall d'Hebron Hospital
    G Poulakou
    Department of Critical Care, Vall d Hebron University Hospital, Barcelona, Spain
    Clin Microbiol Infect 18:374-80. 2012
    ..Increasing vaccination rates among risk-group individuals is warranted to prevent ICU admission and death...
  38. ncbi [Mechanical ventilation associated pneumonia]
    E Diaz
    Servicio de Medicina Intensiva, Hospital Universitari Joan XXIII Tarragona, Universitat Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias, CibeRes, Tarragona, Spain
    Med Intensiva 34:318-24. 2010
    ....
  39. ncbi [Prevention of nosocomial infections: strategies to improve the safety of the patients in the Intensive Care Unit]
    T Lisboa
    Servicio de Cuidados Intensivos, Hospital Universitario Joan XXIII, Universidad Rovira y Virgili, Instituto Pere Virgili, Tarragona, Espana
    Med Intensiva 32:248-52. 2008
    ..Using care bundles, continuing education and feedback on adherence to the measures proposed are key points to improve the safety of patients in the Intensive Care Unit...
  40. ncbi Demographics, guidelines, and clinical experience in severe community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital University Rovira i Virgili, Pere Virgili Health Institut, CIBER Enfermedades Respiratorias CIBERES, Tarragona 43007, Spain
    Crit Care 12:S2. 2008
    ....
  41. ncbi Epidemiology and outcomes of ventilator-associated pneumonia in a large US database
    Jordi Rello
    University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Chest 122:2115-21. 2002
    ..While strategies to prevent the occurrence of VAP may not reduce mortality, they may yield other important benefits to patients, their families, and hospital systems...
  42. ncbi Clinical approach to the patient with suspected ventilator-associated pneumonia
    Loreto Vidaur
    Critical Care Department, University Rovira and Virgili. Institut Pere Virgili, Joan XXIII University Hospital, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Respir Care 50:965-74; discussion 974. 2005
    ..Optimal management should be based on a strategy combining early high doses of an effective agent for a short period of time, which is then simplified in the light of microbiologic information...
  43. ncbi Ventilator-associated pneumonia: issues related to the artificial airway
    Emili Diaz
    Critical Care Department, University Rovira and Virgili. Institut Pere Virgili, Joan XXIII University Hospital, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Respir Care 50:900-6; discussion 906-9. 2005
    ..As many studies suggest that incidence of VAP is highly dependent on the strategies of airway management, health care workers should be alerted to issues related to the artificial airway...
  44. ncbi Reduced burden of bacterial airway colonization with a novel silver-coated endotracheal tube in a randomized multiple-center feasibility study
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Crit Care Med 34:2766-72. 2006
    ..To assess the feasibility and safety of the respiratory infection control (RIC) device, a silver-coated endotracheal tube, and its effect on bacterial burden in the airways...
  45. ncbi The ventilator-associated pneumonia PIRO score: a tool for predicting ICU mortality and health-care resources use in ventilator-associated pneumonia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 134:1208-16. 2008
    ..No score is available to assess severity and stratify mortality risk in ventilator-associated pneumonia (VAP). Our objective was to develop a severity assessment tool for VAP patients...
  46. ncbi Effects of high-dose of intravenous immunoglobulin and antibiotics on survival for severe sepsis undergoing surgery
    Alejandro Rodriguez
    Intensive Care Department of Joan XXIII University Hospital University Rovira and Virgili and Institut Pere Virgili, Tarragona, Spain
    Shock 23:298-304. 2005
    ..We conclude that IVIG administration, when used in combination with adequate antibiotics, improved the survival of surgical ICU patients with intra-abdominal sepsis. The initial choice of antibiotic has a dramatic impact on outcome...
  47. ncbi Radiologic progression of pulmonary infiltrates predicts a worse prognosis in severe community-acquired pneumonia than bacteremia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, CIBER Enfermedades Respiratorias, Carrer Mallafre Guasch, Tarragona, Spain
    Chest 135:165-72. 2009
    ..The objective of this study was to investigate the relative importance of these two factors in the outcome of patients with severe CAP (sCAP)...
  48. ncbi Management of ventilator-associated pneumonia caused by multiresistant bacteria
    Emili Diaz
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili Institut Pere Virgili, Tarragona Spain
    Curr Opin Crit Care 13:45-50. 2007
    ..The inappropriate choice of antibiotics (in nearly one third of episodes) is the most important risk factor for death. Traditionally, a narrow-spectrum drug was used first, and the most potent drugs were reserved for subsequent use...
  49. ncbi Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, CIBERes Enfermedades Respiratorias, IISPV, Mallafre Guasch 4, 43007 Tarragona, Spain
    Crit Care 13:R148. 2009
    ..We describe the clinical and epidemiologic characteristics of the first 32 persons reported to be admitted to the intensive care unit (ICU) due to influenza A (H1N1)v infection in Spain...
  50. ncbi Clinical resolution in patients with suspicion of ventilator-associated pneumonia: a cohort study comparing patients with and without acute respiratory distress syndrome
    Loreto Vidaur
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Tarragona, Spain
    Crit Care Med 33:1248-53. 2005
    ..ARDS patients with VAP take twice as long to resolve fever, whereas hypoxemia should be ignored in defining resolution in this subset...
  51. ncbi Solid organ transplant training objectives for residents
    J R Masclans
    Servicio de Medicina Intensiva, Hospital Vall d Hebron de Barcelona, Instituto de Investigación Vall d Hebron, Universitat Autonoma de Barcelona, CibeRes, Spain
    Med Intensiva 36:584-8. 2012
    ..We conclude that we need a specific training program in complications of SOT, as well as fundamental principles in immunology and immunosuppressor pharmacology...
  52. ncbi Endotracheal tube intraluminal diameter narrowing after mechanical ventilation: use of acoustic reflectometry
    M C Boque
    University Hospital Joan XXIII, University Rovira i Virgili, Mallafre Guasch 4, 43007 Tarragona, Spain
    Intensive Care Med 30:2204-9. 2004
    ..To quantify the incidence and degree of endotracheal tube intraluminal obstruction after mechanical ventilation and its relation to time of intubation...
  53. ncbi Management of ventilator-associated pneumonia in a multidisciplinary intensive care unit: does trauma make a difference?
    Kemal Agbaht
    CIBER Enfermedades Respiratorias, University of Rovira and Virgili, Critical Care Department, Joan XXIII University Hospital, Institut Pere Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Intensive Care Med 33:1387-95. 2007
    ..Antibiotic exposure and timing of pneumonia onset influence ventilator-associated pneumonia (VAP) isolates. The first goal of this investigation was to evaluate whether trauma also influences prevalence of microorganisms...
  54. ncbi Top ten list in antibiotic policy in the ICU
    Emili Diaz
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 122:712-4. 2002
  55. ncbi Ventilator-associated pneumonia in trauma patients is associated with lower mortality: results from EU-VAP study
    M Magret
    Critical Care Department, Sant Joan University Hospital, Reus, Spain
    J Trauma 69:849-54. 2010
    ..Differences in trauma patients developing ventilator-associated pneumonia (VAP) are described regarding etiology and risk factors associated. We aim to describe the differences in outcomes in trauma and nontrauma patients with VAP...
  56. ncbi Prevention of infection in the intensive care unit: current advances and opportunities for the future
    Carmen Lorente
    Critical Care Department, University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Curr Opin Crit Care 8:461-4. 2002
    ..Potential measures of control should focus on the patient, the microorganisms, and the device. A number of recent studies addressing these issues have been published and will be reviewed in this article...
  57. ncbi Management of ventilator-associated pneumonia
    Emili Diaz
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias, Carrer Mallafre Guasch 4, Tarragona 43007, Spain
    Infect Dis Clin North Am 23:521-33. 2009
    ..In recent years, a more dynamic approach has evolved, updating local epidemiology, evaluating VAP and diagnostic tools every day, and assessing host response using clinical and biochemical parameters...
  58. ncbi Gram-negative bacterial pneumonia: aetiology and management
    Despoina Koulenti
    Critical Care Department, Joan XXIII University Hospital, University Rovira y Virgili/Institut PereVirgili, Tarragona, Spain
    Curr Opin Pulm Med 12:198-204. 2006
    ..Early effective antimicrobial treatment is a key for the resolution of infection and improved survival...
  59. ncbi The simple and the simpler in pneumonia diagnosis
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBERes Enfermedades Respiratorias, Carrer Mallafre Guasch, 4 43007, Tarragona, Spain
    Crit Care 11:140. 2007
    ....
  60. ncbi Oral care practices in intensive care units: a survey of 59 European ICUs
    Jordi Rello
    Joan XXIII University Hospital, Critical Care Department, Mallafre Guasch 4, 43007 Tarragona, Spain
    Intensive Care Med 33:1066-70. 2007
    ..To explore the type and frequency of oral care practices in European ICUs and the attitudes, beliefs, and knowledge of health care workers...
  61. ncbi A European care bundle for prevention of ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Vall d Hebron University Hospital, Institut de Recerca Vall d Hebron UAB, CibeRes, Barcelona, Spain
    Intensive Care Med 36:773-80. 2010
    ..One recent approach to facilitating guideline implementation involves the use of care bundles...
  62. ncbi Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia
    Kemal Agbaht
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care Med 35:2064-70. 2007
    ..To assess whether bacteremic ventilator-associated pneumonia (B-VAP) differs in terms of risk factors, organisms, and outcomes from nonbacteremic VAP (NB-VAP)...
  63. ncbi Severity of pneumococcal pneumonia associated with genomic bacterial load
    Jordi Rello
    Critical Care Department, Hospital Universitari Joan XXIII, 43007 Tarragona, Spain
    Chest 136:832-40. 2009
    ..As viral load is useful in viral infections, we hypothesized that bacterial load may be associated with outcomes in patients with pneumococcal pneumonia...
  64. ncbi Diagnosis of ventilator-associated pneumonia: is there a gold standard and a simple approach?
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Curr Opin Infect Dis 21:174-8. 2008
    ..Recent findings in diagnosis are reviewed here...
  65. ncbi C-reactive protein correlates with bacterial load and appropriate antibiotic therapy in suspected ventilator-associated pneumonia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Crit Care Med 36:166-71. 2008
    ....
  66. ncbi Association between 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene with stroke or encephalopathy after cardiac surgery
    Gonzalo Sirgo
    Intensive Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Mallafre Guasch N 4, 43007, Tarragona, Spain
    Intensive Care Med 32:668-75. 2006
    ....
  67. ncbi Improving survival for sepsis: on the cutting edge
    Jordi Rello
    Crit Care Med 31:2807-8. 2003
  68. ncbi Effects of delayed oxygenation assessment on time to antibiotic delivery and mortality in patients with severe community-acquired pneumonia
    Stijn I Blot
    Intensive Care Department, Ghent University Hospital, Faculty of Medicine and Health Science, Ghent University, Belgium
    Crit Care Med 35:2509-14. 2007
    ....
  69. ncbi Optimal management therapy for Pseudomonas aeruginosa ventilator-associated pneumonia: an observational, multicenter study comparing monotherapy with combination antibiotic therapy
    Jose Garnacho-Montero
    Critical Care and Emergency Department, Hospital Universitario Virgen del Rocio, Sevilla, Spain
    Crit Care Med 35:1888-95. 2007
    ..To evaluate whether one antibiotic achieves equal outcomes compared with combination antibiotic therapy in patients with Pseudomonas aeruginosa ventilator-associated pneumonia...
  70. ncbi Severity of illness assessment for managing community-acquired pneumonia
    Jordi Rello
    Intensive Care Med 33:2043-4. 2007
  71. ncbi Antibiotic use and the risk of pneumonia: 20 years of studies, but where are we now?
    Emili Diaz
    Clin Infect Dis 38:1409-11. 2004
  72. ncbi [Cyclic rotation of antibiotics. Is all that glitters gold?]
    Alberto Sandiumenge
    Servicio de Cuidados Intensivos Hospital Universitario Joan XXIII Universitat Rovira i Virgili Tarragona España
    Enferm Infecc Microbiol Clin 21:93-100. 2003
    ..In this article several methodological considerations are suggested for future studies testing this new antibiotic strategy...
  73. ncbi Acinetobacter baumannii: a threat for the ICU?
    Jordi Rello
    Intensive Care Med 29:350-1. 2003
  74. ncbi Prospective observational study of bacteremic pneumococcal pneumonia: Effect of discordant therapy on mortality
    Manel Lujan
    Pulmonary Department, , Sabadell, Barcelona, Spain
    Crit Care Med 32:625-31. 2004
    ..Clinical outcome is worse in those patients receiving antimicrobial therapy that in vitro testing suggests would be ineffective...
  75. ncbi Drug-resistant pneumococcal pneumonia: clinical relevance and related factors
    Javier Aspa
    Servicio de Neumologia, Hospital de la Princesa, Madrid, Spain
    Clin Infect Dis 38:787-98. 2004
    ..In summary, the rate of resistance to beta -lactams and macrolides among S. pneumoniae that cause CAP remains high, but such resistance does not result in increased morbidity...
  76. ncbi Clinical cure and survival in Gram-positive ventilator-associated pneumonia: retrospective analysis of two double-blind studies comparing linezolid with vancomycin
    Marin H Kollef
    Pulmonary and Critical Care Division, Department of Internal Medicine, School of Medicine, Washington University, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Intensive Care Med 30:388-94. 2004
    ..To assess the effect of baseline variables, including treatment, on clinical cure and survival rates in patients with Gram-positive, ventilator-associated pneumonia (VAP)...
  77. ncbi Community-acquired bloodstream infection in critically ill adult patients: impact of shock and inappropriate antibiotic therapy on survival
    Jordi Valles
    Intensive Care Department, Hospital de Sabadell, Spain
    Chest 123:1615-24. 2003
    ....
  78. ncbi Secretion of the toxin ExoU is a marker for highly virulent Pseudomonas aeruginosa isolates obtained from patients with hospital-acquired pneumonia
    Grant S Schulert
    Department of Microbiology/Immunology, Northwestern University, Chicago, Illinois 60611, USA
    J Infect Dis 188:1695-706. 2003
    ..Together, these findings suggest that secretion of ExoU is a marker for highly virulent strains of P. aeruginosa...
  79. ncbi Clinical impact of pneumonia caused by Acinetobacter baumannii in intubated patients: a matched cohort study
    Jose Garnacho
    Hospital Universitario Virgen del Rocio, Seville, Spain
    Crit Care Med 31:2478-82. 2003
    ..3 and 36.6 days, respectively (p = nonsignificant). CONCLUSION: In intubated patients, pneumonia by A. baumannii is not significantly associated with attributable mortality rate or an increased length of intensive care unit stay...
  80. ncbi A 7-year study of severe hospital-acquired pneumonia requiring ICU admission
    Jordi Valles
    Critical Care Center, Hospital Sabadell, Institut Universitari Parc Tauli Universitat Autónoma de Barcelona, Parc Tauli s n, 08208, Barcelona, Spain
    Intensive Care Med 29:1981-8. 2003
    ..To examine the characteristics, prognostic factors, and outcome of patients with severe hospital-acquired pneumonia admitted to the ICU...
  81. ncbi Patterns of colonization by Pseudomonas aeruginosa in intubated patients: a 3-year prospective study of 1,607 isolates using pulsed-field gel electrophoresis with implications for prevention of ventilator-associated pneumonia
    Jordi Valles
    Critical Care Center, Hospital Sabadell and UDIAT Diagnostic Center, Institut Universitari, Universitat Autonoma Barcelona, Parc Tauli s n, 08208 Sabadell, Spain
    Intensive Care Med 30:1768-75. 2004
    ..To identify routes and patterns of colonization with Pseudomonas aeruginosa in intubated patients to design strategies of prevention for respiratory infection...
  82. ncbi Benefits of minocycline and rifampin-impregnated central venous catheters. A prospective, randomized, double-blind, controlled, multicenter trial
    Cristóbal León
    Intensive Care Unit, Hospital Universitario de Valme, Universidad de Sevilla, Carretera de Cádiz s n, 41014 Sevilla, Spain
    Intensive Care Med 30:1891-9. 2004
    ..To determine the efficacy of minocycline and rifampin-impregnated catheters compared to non-impregnated catheters in critically ill patients...
  83. ncbi Influence of renal function on the pharmacokinetics of piperacillin/tazobactam in intensive care unit patients during continuous venovenous hemofiltration
    Alazne Arzuaga
    , Facultad de Farmacia, Paseo de la Universidad no. 7, 01006 Vitoria-Gasteiz, Spain
    J Clin Pharmacol 45:168-76. 2005
    ..The extracorporeal clearance of piperacillin/tazobactam is clinically significant in patients with CL(CR) > 50 mL/min, in which the risk of underdosing and clinical failure is important and extra doses are required...
  84. ncbi A worldwide perspective of atypical pathogens in community-acquired pneumonia
    Forest W Arnold
    Division of Infectious Diseases, University of Louisville, Louisville, KY 40292, USA
    Am J Respir Crit Care Med 175:1086-93. 2007
    ..In different regions of the world, monotherapy with a beta-lactam antimicrobial is common...
  85. ncbi Optimal therapy for methicillin-resistant Staphylococcus aureus pneumonia: what is the best dosing regimen?
    Jordi Rello
    Chest 130:938-40. 2006
  86. ncbi Impact of antibiotic guideline compliance on duration of mechanical ventilation in critically ill patients with community-acquired pneumonia
    Andrew F Shorr
    Pulmonary and Critical Care Section, Department of Medicine, Room 2A 38D, Washington Hospital Center, Washington, DC 20010, USA
    Chest 130:93-100. 2006
    ..Our goal was to assess the impact of following these guidelines, such as those from the Infectious Disease Society of America (IDSA), on the duration of mechanical ventilation (MV)...
  87. ncbi Optimal therapy for severe pneumococcal community-acquired pneumonia
    Manel Lujan
    Pulmonary Service, Corporació Parc Taulí Institut Universitari Parc Taulí, Sabadell, Spain
    Intensive Care Med 32:971-80. 2006
    ..Prospective, randomized clinical trials of pneumonia patients with a pneumonia severity index score above 90 are warranted to define optimal antibiotic regimens...
  88. ncbi Type III protein secretion is associated with poor clinical outcomes in patients with ventilator-associated pneumonia caused by Pseudomonas aeruginosa
    Alan R Hauser
    Department of Microbiology/Immunology, Northwestern University, Chicago, IL, USA
    Crit Care Med 30:521-8. 2002
    ..Our findings support the hypothesis that antibodies targeted against these proteins may be useful as adjunctive therapy in intubated patients with P. aeruginosa colonization or infection...
  89. ncbi Choosing the right combination therapy in severe community-acquired pneumonia
    Grant W Waterer
    School of Medicine and Pharmacology, University of Western Australia, MRF Building, Royal Perth Hospital, GPO Box X2213, Perth 6847, Australia
    Crit Care 10:115. 2006
    ..Several mechanisms exist by which quinolones could be inferior to macrolides in combination therapy, so if these findings are confirmed by other groups they have significant implications for physicians treating patients with severe CAP...
  90. ncbi Prevention and diagnosis of ventilator-associated pneumonia: a survey on current practices in Southern Spanish ICUs
    Rafael Sierra
    Intensive Care Unit, Puerta del Mar University Hospital, University of Cadiz, Spain
    Chest 128:1667-73. 2005
    ..To assess the implementation of selected ventilator-associated pneumonia (VAP) prevention strategies, and to learn how VAP is diagnosed in the ICUs of Southern Spain...
  91. ncbi Optimal outcome in patients with community-acquired pneumonia: Take the main course before the dessert
    Jordi Rello
    Crit Care Med 33:1149. 2005
  92. ncbi Changing physicians' behavior in the intensive care unit
    Jordi Rello
    Crit Care Med 30:2593-4. 2002
  93. ncbi An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome
    Victor L Yu
    Division of Infectious Disease, University of Pittsburgh, PA, USA
    Clin Infect Dis 37:230-7. 2003
    ..beta-Lactam antibiotics should still be useful for treatment of pneumococcal infections that do not involve cerebrospinal fluid, regardless of in vitro susceptibility, as determined by current NCCLS breakpoints...
  94. ncbi Multicenter, double-blind, placebo-controlled study of the use of filgrastim in patients hospitalized with pneumonia and severe sepsis
    Richard K Root
    University of Washington, Seattle, USA
    Crit Care Med 31:367-73. 2003
    ....
  95. ncbi Bacteraemic pneumococcal pneumonia: impact of HIV on clinical presentation and outcome
    Charles Feldman
    Division of Pulmonology, Department of Medicine, Johannesburg Hospital, University of the Witwatersrand, Medical School, 7 York Road, Parktown 2193, Johannesburg, South Africa
    J Infect 55:125-35. 2007
    ....
  96. ncbi Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia
    Larry M Baddour
    Mayo Clinic, Rochester, NY, USA
    Am J Respir Crit Care Med 170:440-4. 2004
    ..Combination antibiotic therapy improved survival among critically ill patients with bacteremic pneumococcal illness...
  97. ncbi Finding the hidden target in Pseudomonas aeruginosa management
    Thiago Lisboa
    Crit Care Med 36:2675-6. 2008
  98. ncbi The presence of pneumococcal bacteremia does not influence clinical outcomes in patients with community-acquired pneumonia: results from the Community-Acquired Pneumonia Organization (CAPO) International Cohort study
    Jose Bordon
    Department of Medicine, Section of Infectious Diseases, Providence Hospital, 1150 Varnum St, NE, Washington, DC 20017, USA
    Chest 133:618-24. 2008
    ..The objective of this study was to investigate whether the presence of pneumococcal bacteremia influences the clinical outcomes of hospitalized patients with CAP...
  99. ncbi Effect of enriched thioglycolate on direct examination of respiratory specimens and guiding initial empirical therapy in intubated patients with pneumonia: a prospective, randomized study
    Jordi Rello
    Intensive Care Department, Hospital de Sabadell, Sabadell, Barcelona, Spain
    Crit Care Med 30:311-4. 2002
    ..5% of samples transported in saline solution (p <.05). CONCLUSION: When protected specimen brush samples are obtained, thioglycolate may contribute to early identification of the pathogen and may guide the initial empirical therapy...