Ramon Planas

Summary

Affiliation: Hospital Universitari Germans Trias i Pujol
Country: Spain

Publications

  1. ncbi Natural history of decompensated hepatitis C virus-related cirrhosis. A study of 200 patients
    Ramon Planas
    Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    J Hepatol 40:823-30. 2004
  2. ncbi [Induction therapy with interferon alfa-2a in compensated hepatitis C virus-related cirrhosis. Randomized, multicenter study]
    Ramon Planas
    Hospital Universitari Germans Trias i Pujol Badalona BArcelona Spain
    Med Clin (Barc) 118:641-4. 2002
  3. ncbi Results of a study of prolonging treatment with pegylated interferon-alpha2a plus ribavirin in HIV/HCV-coinfected patients with no early virological response
    Daniel Fuster
    HIV Clinical Unit Fundació de Lluita contra la SIDA Internal Medicine Service University Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Barcelona, Spain
    Antivir Ther 11:473-82. 2006
  4. ncbi Serum concentrations of insulin-like growth factor-I (igf-I) as a marker of liver fibrosis in patients with chronic hepatitis C
    Vicente Lorenzo-Zúñiga
    Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet s n, 08916, Badalona, Barcelona, Spain
    Dig Dis Sci 52:3245-50. 2007
  5. ncbi Early HCV dynamics on Peg-interferon and ribavirin in HIV/HCV co-infection: indications for the investigation of new treatment approaches
    Angel Luis Ballesteros
    HIV Clinical Unit, University Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Barcelona, Spain
    AIDS 18:59-66. 2004
  6. ncbi Differences in virological response to pegylated interferon and ribavirin between hepatitis C virus (HCV)-monoinfected and HCV-HIV-coinfected patients
    Cristina Tural
    HIV Clinical Unit, Internal Medicine Department, Fundació de la Lluita contra la SIDA, University Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Barcelona, Spain
    Antivir Ther 13:1047-55. 2008
  7. ncbi Poor response to hepatitis C virus (HCV) therapy in HIV- and HCV-coinfected patients is not due to lower adherence to treatment
    Ricard Sola
    Liver Section, Hospital del Mar, Institut Municipal d Investigacio Medica, Universitat Autonoma de Barcelona, 08003 Barcelona, Spain
    AIDS Res Hum Retroviruses 22:393-400. 2006
  8. doi Incidence and prognosis of different types of functional renal failure in cirrhotic patients with ascites
    Silvia Montoliu
    Liver Unit, Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    Clin Gastroenterol Hepatol 8:616-22; quiz e80. 2010
  9. doi Long-term clinical course of decompensated alcoholic cirrhosis: a prospective study of 165 patients
    Marco Antonio Alvarez
    Departament of Gastroenterology, Liver Unit, Hospital Universitari Germans Trias i Pujol, Spain
    J Clin Gastroenterol 45:906-11. 2011
  10. ncbi Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats
    Vicente Lorenzo-Zúñiga
    Departments of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain
    Hepatology 37:551-7. 2003

Collaborators

Detail Information

Publications44

  1. ncbi Natural history of decompensated hepatitis C virus-related cirrhosis. A study of 200 patients
    Ramon Planas
    Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    J Hepatol 40:823-30. 2004
    ..Since few data are available concerning the clinical course of decompensated hepatitis C virus (HCV)-related cirrhosis, the aim of the present study was to define the natural long-term course after the first hepatic decompensation...
  2. ncbi [Induction therapy with interferon alfa-2a in compensated hepatitis C virus-related cirrhosis. Randomized, multicenter study]
    Ramon Planas
    Hospital Universitari Germans Trias i Pujol Badalona BArcelona Spain
    Med Clin (Barc) 118:641-4. 2002
    ..Based on HCV kinetics, daily IFN may improve response rates...
  3. ncbi Results of a study of prolonging treatment with pegylated interferon-alpha2a plus ribavirin in HIV/HCV-coinfected patients with no early virological response
    Daniel Fuster
    HIV Clinical Unit Fundació de Lluita contra la SIDA Internal Medicine Service University Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Barcelona, Spain
    Antivir Ther 11:473-82. 2006
    ..To assess the efficacy and safety of an extended treatment period in HIV/hepatitis C virus (HCV)-coinfected patients without early virological response (EVR)...
  4. ncbi Serum concentrations of insulin-like growth factor-I (igf-I) as a marker of liver fibrosis in patients with chronic hepatitis C
    Vicente Lorenzo-Zúñiga
    Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet s n, 08916, Badalona, Barcelona, Spain
    Dig Dis Sci 52:3245-50. 2007
    ..In conclusion, IGF-I synthesis is disturbed in CHC and reflects the severity of the liver fibrosis. Combined therapy improves serum IGF-I levels. IGF-I could represent a good, noninvasive marker of liver fibrosis...
  5. ncbi Early HCV dynamics on Peg-interferon and ribavirin in HIV/HCV co-infection: indications for the investigation of new treatment approaches
    Angel Luis Ballesteros
    HIV Clinical Unit, University Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Barcelona, Spain
    AIDS 18:59-66. 2004
    ..To investigate the baseline mutations in the interferon sensitivity determining region (ISDR)2209-2248 in the non-structural 5A protein of HCV according to genotype...
  6. ncbi Differences in virological response to pegylated interferon and ribavirin between hepatitis C virus (HCV)-monoinfected and HCV-HIV-coinfected patients
    Cristina Tural
    HIV Clinical Unit, Internal Medicine Department, Fundació de la Lluita contra la SIDA, University Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Barcelona, Spain
    Antivir Ther 13:1047-55. 2008
    ..Suboptimal doses of ribavirin have been suggested to explain the diminished efficacy of pegylated interferon (PEG-IFN) plus ribavirin in hepatitis C virus (HCV)-HIV-coinfected patients...
  7. ncbi Poor response to hepatitis C virus (HCV) therapy in HIV- and HCV-coinfected patients is not due to lower adherence to treatment
    Ricard Sola
    Liver Section, Hospital del Mar, Institut Municipal d Investigacio Medica, Universitat Autonoma de Barcelona, 08003 Barcelona, Spain
    AIDS Res Hum Retroviruses 22:393-400. 2006
    ..In addition to improved adherence, in coinfected patients more aggressive therapeutic strategies may be necessary to achieve SVR...
  8. doi Incidence and prognosis of different types of functional renal failure in cirrhotic patients with ascites
    Silvia Montoliu
    Liver Unit, Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    Clin Gastroenterol Hepatol 8:616-22; quiz e80. 2010
    ..We assessed the incidence and prognosis of different types of functional renal failure in cirrhotic patients with ascites and investigated prognostic factors for these disorders...
  9. doi Long-term clinical course of decompensated alcoholic cirrhosis: a prospective study of 165 patients
    Marco Antonio Alvarez
    Departament of Gastroenterology, Liver Unit, Hospital Universitari Germans Trias i Pujol, Spain
    J Clin Gastroenterol 45:906-11. 2011
    ....
  10. ncbi Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats
    Vicente Lorenzo-Zúñiga
    Departments of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain
    Hepatology 37:551-7. 2003
    ..Oral conjugated bile acids may be useful in preventing bacterial translocation, endotoxemia, and spontaneous bacterial perotonitis in cirrhotic patients...
  11. doi Evolutionary dynamics of the E1-E2 viral populations during combination therapy in non-responder patients chronically infected with hepatitis C virus subtype 1b
    Verónica Saludes
    Microbiology Service, Fundació Institut d Investigació en Ciències de la Salut Germans Trias i Pujol, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    Infect Genet Evol 13:1-10. 2013
    ..In conclusion, although diverse evolutionary patterns with no apparent common adaptive changes were observed during therapy, treatment failure was characterised by a decline in genetic diversity...
  12. doi Effect of an induction period of pegylated interferon-α2a and ribavirin on early virological response in HIV-HCV-coinfected patients: results from the CORAL-2 study
    Cristina Tural
    HIV Clinical Unit, Internal Medicine Department and Fundació de la Lluita contra la SIDA, University Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Barcelona, Spain
    Antivir Ther 16:833-41. 2011
    ..It is uncertain whether a 4-week induction period of pegylated interferon and ribavirin increases early virological response (EVR) in HIV-HCV-coinfected patients...
  13. ncbi Natural history of patients hospitalized for management of cirrhotic ascites
    Ramon Planas
    Liver Section, Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain
    Clin Gastroenterol Hepatol 4:1385-94. 2006
    ..The aims of this study were to define the natural history of cirrhotic ascites and to identify prognostic factors for dilutional hyponatremia (DH), RA, HRS, and survival...
  14. ncbi Short communication. Baseline factors associated with haematological toxicity that leads to a dosage reduction of pegylated interferon-alpha2a and ribavirin in HIV- and HCV-coinfected patients on HCV antiviral therapy
    Daniel Fuster
    HIV Clinical Unit Fundació de la Lluita contra la SIDA Internal Medicine Service and Hepatology Unit, University Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    Antivir Ther 10:841-7. 2005
    ..To assess the baseline factors associated with haematological toxicity that lead to ribavirin or pegylated interferon (peginterferon) dosage reductions in hepatitis C and human immunodeficiency virus (HCV/HIV)-coinfected patients...
  15. ncbi Probability of liver cancer and survival in HCV-related or alcoholic-decompensated cirrhosis. A study of 377 patients
    Ricard Sola
    Liver Section, Department of Gastroenterology, Hospital del Mar, Barcelona, Spain
    Liver Int 26:62-72. 2006
    ..Although chronic alcohol intake and chronic hepatitis C may progress to cirrhosis and hepatocellular carcinoma (HCC), few data are available about survival and probability of developing HCC in decompensated cirrhosis of both aetiologies...
  16. doi Prophylactic treatment with escitalopram of pegylated interferon alfa-2a-induced depression in hepatitis C: a 12-week, randomized, double-blind, placebo-controlled trial
    Crisanto Diez-Quevedo
    Department of Psychiatry, Hospital Universitari Germans Trias i Pujol, Autonomous University of Barcelona, Ctra de Canyet s n, 08916 Badalona, Spain
    J Clin Psychiatry 72:522-8. 2011
    ..Antidepressants are useful for its treatment, but whether they can also be used for prevention has yet to be established...
  17. pmc Relevance of baseline viral genetic heterogeneity and host factors for treatment outcome prediction in hepatitis C virus 1b-infected patients
    Verónica Saludes
    Microbiology Service, Fundació Institut d Investigació en Ciències de la Salut Germans Trias i Pujol, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain CIBER Epidemiología y Salud Pública CIBERESP, Barcelona, Spain
    PLoS ONE 8:e72600. 2013
    ..We aimed to develop a predictive model of treatment response based on a combination of baseline clinical and viral parameters...
  18. pmc Baseline prediction of combination therapy outcome in hepatitis C virus 1b infected patients by discriminant analysis using viral and host factors
    Verónica Saludes
    Microbiology Service, Fundació Institut d Investigació en Ciències de la Salut Germans Trias i Pujol, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    PLoS ONE 5:e14132. 2010
    ..We aimed to identify pre-treatment clinical and virological parameters associated with treatment failure, as well as to assess whether therapy outcome could be predicted at baseline...
  19. doi Hepatitis C virus sequences from different patients confirm the existence and transmissibility of subtype 2q, a rare subtype circulating in the metropolitan area of Barcelona, Spain
    Elisa Martro
    Microbiology Service, Health Sciences Research Institute of Germans Trias i Pujol Foundation, Germans Trias i Pujol Hospital, Autonoma University of Barcelona, Badalona, Spain
    J Med Virol 83:820-6. 2011
    ....
  20. ncbi Rat CCl(4)-induced cirrhosis plus total portal vein ligation: a new model for the study of hyperammonaemia and brain oedema
    Mireia Miquel
    Germans Trias i Pujol Health Science Research Institute, Badalona, Spain
    Liver Int 30:979-87. 2010
    ..Animal models used to study hyperammonaemic disorders related to chronic liver disease are unsatisfactory. These animals only develop hyperammonaemia and brain oedema when fed with diets supplemented with amonium acetate...
  21. ncbi Functional abnormalities of the motor tract in the rat after portocaval anastomosis and after carbon tetrachloride induction of cirrhosis
    Marc Oria
    Liver Unit, Hospital Universitari Vall d Hebron, Department of Medicine, Universitat Autonoma de Barcelona, Passeig Vall d Hebron 119 129, 08035, Barcelona, Spain
    Metab Brain Dis 21:297-308. 2006
    ..Impairment in the function of the first neuron of the motor tract (corticospinal tract) has been demonstrated in patients with cirrhosis and minimal hepatic encephalopathy...
  22. pmc Rifaximin, but not growth factor 1, reduces brain edema in cirrhotic rats
    Gemma Odena
    Hepatology Unit, Department of Gastroenterology, Germans Trias i Pujol Health Science Research Institute, 08916 Badalona, Spain
    World J Gastroenterol 18:2084-91. 2012
    ..To compare rifaximin and insulin-like growth factor (IGF)-1 treatment of hyperammonemia and brain edema in cirrhotic rats with portal occlusion...
  23. ncbi Role of viral kinetics under HCV therapy in HIV/HCV-coinfected patients
    Angel Luis Ballesteros
    HIV Clinical Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Barcelona, Spain
    J Antimicrob Chemother 55:824-7. 2005
    ....
  24. ncbi Effect of the administration of fermentable and non-fermentable dietary fibre on intestinal bacterial translocation in ascitic cirrhotic rats
    Ramon Bartolí
    Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Carretera del Canyet s n, 08916, Badalona, Catalonia, Spain
    Clin Nutr 26:383-7. 2007
    ..Both fermentable and non-fermentable fibre avoided intestinal bacterial translocation (IBT) in animal models of gut starvation and critical illness...
  25. pmc Evaluation of a new assay in comparison with reverse hybridization and sequencing methods for hepatitis C virus genotyping targeting both 5' noncoding and nonstructural 5b genomic regions
    Elisa Martro
    Microbiology Department, Hospital Universitari Germans Trias i Pujol, Ctra de Canyet, s n 08916 Badalona, Spain
    J Clin Microbiol 46:192-7. 2008
    ....
  26. ncbi New method for isolation of rat lamina propria macrophages in colonic tissue
    Ana Bargalló
    Gastroenterology Department, Hospital de Sant Joan Despí Moisès Broggi, Sant Joan Despi, Barcelona, Spain Germans Trias i Pujol Foundation IGTP, Badalona, Spain
    J Immunol Methods 408:132-6. 2014
    ..Significant differences are observed when analyzing the effect of the isolation method on the cell number, viability and phenotype. This has important implications when further functional studies are required. ..
  27. doi A prospective study of lymphocyte subpopulations and regulatory T cells in patients with chronic hepatitis C virus infection developing interferon-induced thyroiditis
    Berta Soldevila
    Department of Medicine, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    Clin Endocrinol (Oxf) 75:535-43. 2011
    ..The aim of this study was to assess different peripheral blood lymphocyte subpopulations, mainly CD4(+) CD25(+) CD127low/-FoxP3(+) regulatory T cells (Tregs), in patients with chronic hepatitis C virus (HCV) infection who developed IIT...
  28. ncbi Mitochondrial effects of a 24-week course of pegylated-interferon plus ribavirin in asymptomatic HCV/HIV co-infected patients on long-term treatment with didanosine, stavudine or both
    Angel Luis Ballesteros
    HIV Clinical Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Barcelona, Spain
    Antivir Ther 9:969-77. 2004
    ....
  29. ncbi Combining steroids with enteral nutrition: a better therapeutic strategy for severe alcoholic hepatitis? Results of a pilot study
    Marco A Alvarez
    Department of Gastroenterology, University Hospital Germans Trias i Pujol, Badalona, Catalonia, Spain
    Eur J Gastroenterol Hepatol 16:1375-80. 2004
    ..We report a pilot study of combined treatment with TEN and a shorter course of steroids in patients with severe alcoholic hepatitis...
  30. ncbi Spironolactone alone or in combination with furosemide in the treatment of moderate ascites in nonazotemic cirrhosis. A randomized comparative study of efficacy and safety
    Justiniano Santos
    Department of Gastroenterology, Hospital Universitari Germans Tri as i Pujol, Carretera del Canyet, S N, 08916, Badalona, Spain
    J Hepatol 39:187-92. 2003
    ..The most rational treatment of moderate ascites is spironolactone alone or in combination with furosemide. However, it is unknown which of these two treatment schedules is preferable...
  31. doi High-definition colonoscopy and risk factors for recurrence of advanced adenomas in patients with a personal history of polyps
    Vicente Lorenzo-Zúñiga
    Department of Gastroenterology, Endoscopy Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona
    Eur J Gastroenterol Hepatol 23:425-30. 2011
    ....
  32. doi [Clinical use of telaprevir: stopping rules, predicting response, treatment length, and management of adverse effects]
    Cristina Tural
    Unidad Clínica de VIH, Servicio de Medicina Interna, Hospital Germans Trias i Pujol, Badalona, Universitat Autonoma de Barcelona, Barcelona, Espana
    Enferm Infecc Microbiol Clin 31:19-25. 2013
    ..If these effects occur, the main measures that should be adopted are reduction of the ribavirin dose in anemia, and close monitoring and treatment cessation in skin rash, depending on its spread and severity...
  33. ncbi [Treatment of hepatitis B virus infection: present and future]
    Ramon Planas
    Unidad de Hepatologia, Servicio de Aparato Digestivo, CIBERehd, Universidad Autonoma de Barcelona, Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain
    Gastroenterol Hepatol 31:349-55. 2008
    ..And finally, the duration and modification of the treatment based on the answer to itself. The objective of this article is a practical revision of the present management of the infection by the HVB...
  34. ncbi Enterococcus gallinarum bacteriascites in a patient with active tuberculosis and HCV cirrhosis
    Marco A Alvarez
    Am J Gastroenterol 97:2681-2. 2002
  35. ncbi Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis
    Roberto J Groszmann
    Yale University School of Medicine, Veterans Affairs Connecticut Healthcare System, West Haven, CT 06516, USA
    N Engl J Med 353:2254-61. 2005
    ..Nonselective beta-adrenergic blockers decrease portal pressure and prevent variceal hemorrhage. Their effectiveness in preventing varices is unknown...
  36. ncbi Hospital admission is a relevant source of hepatitis C virus acquisition in Spain
    Eva Martinez-Bauer
    Liver Unit, Hospital Clinic de Barcelona, IDIBAPS, Ciber de Enfermedades Hepaticas y Digestivas, CIBERehd, Spain
    J Hepatol 48:20-7. 2008
    ..The aim of this study was to investigate the current relevance of nosocomial HCV infection...
  37. ncbi Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosis
    Cristina Ripoll
    Veterans Affairs CT Healthcare System, Yale University School of Medicine, West Haven, Connecticut 06516, USA
    Gastroenterology 133:481-8. 2007
    ....
  38. ncbi The management of ascites in cirrhosis: report on the consensus conference of the International Ascites Club
    Kevin P Moore
    Centre for Hepatology, Royal Free and University College Medical School, UCL, London, United Kingdom
    Hepatology 38:258-66. 2003
    ..Liver transplantation should be considered for all ascitic patients, and this should preferably be performed prior to the development of renal dysfunction to prevent further compromise of their prognosis...
  39. ncbi Daily norfloxacin is more effective than weekly rufloxacin in prevention of spontaneous bacterial peritonitis recurrence
    Tilman M Bauer
    Liver Unit, IMD, Hospital Clinic, IDIBAPS, University of Barcelona, Spain
    Dig Dis Sci 47:1356-61. 2002
    ..The development of quinolone-resistant E. coli in feces may be an important problem in patients on long-term quinolone prophylaxis...
  40. ncbi Comparison of rifaximin and lactitol in the treatment of acute hepatic encephalopathy: results of a randomized, double-blind, double-dummy, controlled clinical trial
    Antoni Mas
    Liver Unit, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    J Hepatol 38:51-8. 2003
    ..The efficacy and safety of rifaximin in comparison with lactitol in the treatment of acute hepatic encephalopathy was assessed in a prospective randomized, double-blind, double-dummy, controlled trial...
  41. ncbi [Risk of transmission of HIV or hepatitis B or C viruses from an infected physician. Preventive measures]
    Miquel Bruguera
    Servicio de Hepatologia, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 129:309-13. 2007
  42. ncbi Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial
    Josep M Llovet
    Liver Unit, Digestive Disease Institute, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Lancet 359:1734-9. 2002
    ..There is no standard treatment for unresectable hepatocellular carcinoma. Arterial embolisation is widely used, but evidence of survival benefits is lacking...
  43. ncbi Platelet count is not a predictor of the presence or development of gastroesophageal varices in cirrhosis
    Amir A Qamar
    Brigham and Women s Hospital, Boston, MA 02446, USA
    Hepatology 47:153-9. 2008
    ..Patients with mild portal hypertension whose PLT remains greater than 100,000 have significantly less risk of GEV. Although HVPG correlates somewhat with PLT, changes in PLT cannot be used as a surrogate for HVPG changes...
  44. ncbi Advanced liver fibrosis in HIV/HCV-coinfected patients on antiretroviral therapy
    Daniel Fuster
    HIV Clinical Unit Department, University Hospital Germans Trias i Pujol, Universitat Autonoma de Barcelona UAB, 08916 Badalona, Barcelona, Spain
    AIDS Res Hum Retroviruses 20:1293-7. 2004
    ..HIV infection is associated with advanced liver fibrosis. HIV/HCV-coinfected individuals on HAART are at risk of developing end-stage liver disease despite virological success and immunological reconstitution...