Research Topics
| V PeraltaSummaryAffiliation: Hospital Virgen del Camino Country: Spain Publications
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Publications
Classifying psychotic disorders: issues regarding categorial vs. dimensional approaches and time frame to assess symptomsVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea, Pamplona, Spain
Eur Arch Psychiatry Clin Neurosci 252:12-8. 2002..It is concluded that classification of psychotic disorders is highly dependent upon the time frame considered to assess symptoms and that dimensional classifications do have higher predictive power than categorical ones...
The low- and higher-order factor structure of symptoms in patients with a first episode of psychosisVictor Peralta
Psychiatry Unit B, Complejo Hospitalario de Navarra, Pamplona, Spain Electronic address
Schizophr Res 147:116-24. 2013..The phenotype of psychotic disorders is presumed to be heterogeneous, but the best way to describe this heterogeneity remains unclear...
Risk factors, pre-morbid functioning and episode correlates of neurological soft signs in drug-naive patients with schizophrenia-spectrum disordersV Peralta
Psychiatry Section B, Complejo Hospitalario de Navarra, Pamplona, Spain
Psychol Med 41:1279-89. 2011..This study examined NSS in first-episode psychotic patients with respect to their factor structure and associations with risk factors, pre-morbid characteristics, psychopathology and spontaneous extrapyramidal syndromes...
Characterization of spontaneous Parkinsonism in drug-naive patients with nonaffective psychotic disordersVictor Peralta
Psychiatry Section B, Complejo Hospitalario de Navarra, Irunlarrea 3, 31008, Pamplona, Spain
Eur Arch Psychiatry Clin Neurosci 262:131-8. 2012..The NINDS criteria for probable SP, i.e., presence of any two of the three core parkinsonian signs, seem to be the most suitable for clinical and research purposes...
Familial liability and schizophrenia phenotypes: a polydiagnostic approachVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008, Pamplona, Spain
Schizophr Res 96:125-34. 2007..Using a polydiagnostic approach we examined the relationship between familial liability and alternative schizophrenia phenotypes...
Patterns of symptoms in neuroleptic-naive patients with schizophrenia and related psychotic disorders before and after treatmentV Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008, Pamplona, Spain
Psychiatry Res 105:97-105. 2001..It is concluded that caution is warranted when using the three-factor model of schizophrenic symptoms as it may not be stable at different phases of the illness...
Classification issues in catatoniaV Peralta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Eur Arch Psychiatry Clin Neurosci 251:I14-6. 2001..When definitions are more restrictive as in Leonhard's system, catatonia seems to be better accommodated as a "third psychosis", i.e. described by the concept of cycloid psychosis...
Cycloid psychosis: an examination of the validity of the conceptVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008 Pamplona, Spain
Curr Psychiatry Rep 9:184-92. 2007..The existence of putative subtypes is also likely, and the differentiation between affective and nonaffective subtypes has received some support...
The deficit syndrome of the psychotic illness. A clinical and nosological studyVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008 Pamplona, Spain
Eur Arch Psychiatry Clin Neurosci 254:165-71. 2004..The deficit syndrome may be diagnosed irrespective of the specific categories of psychotic disorders...
The relationship between syndromes of the psychotic illness and familial liability to schizophrenia and major mood disordersVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008 Pamplona, Spain
Schizophr Res 91:200-9. 2007..The aim of this study is to further examine this issue by analyzing a large sample of psychotic probands and their first-degree relatives...
Obstetric complications and neurological abnormalities in neuroleptic-naive psychotic patientsVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008, Pamplona, Spain
Eur Arch Psychiatry Clin Neurosci 256:407-13. 2006..Having a history of OCs does not convey a vulnerability for developing drug-induced neurological signs in the short term...
Cycloid psychosisVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Int Rev Psychiatry 17:53-62. 2005..Future studies should examine putative subtypes of the disorder in relation to etiological, pathophysiological and clinical variables...
The nosology of psychotic disorders: a comparison among competing classification systemsVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Schizophr Bull 29:413-25. 2003..These results make clear the problems inherent in drawing well-defined boundaries between psychotic disorders...
Diagnostic significance of Schneider's first-rank symptoms in schizophrenia. Comparative study between schizophrenic and non-schizophrenic psychotic disordersV Peralta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Br J Psychiatry 174:243-8. 1999..Despite the lack of consistent empirical support, modern diagnostic criteria of schizophrenia give particular emphasis to Schneider's first-rank symptoms (FRSs)...
How many and which are the psychopathological dimensions in schizophrenia? Issues influencing their ascertainmentV Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, E 31008, Pamplona, Spain
Schizophr Res 49:269-85. 2001..A hierarchical approach for organizing the complex dimensional structure of schizophrenic symptoms is proposed...
Exploring the borders of the schizoaffective spectrum: a categorical and dimensional approachVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
J Affect Disord 108:71-86. 2008..We aimed at examining the nature of such a relationship in a mixed sample of psychotic disorders by using a dimensional and categorical approach to psychopathology...
Neuromotor abnormalities in neuroleptic-naive psychotic patients: antecedents, clinical correlates, and prediction of treatment responseVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008 Pamplona, Spain
Compr Psychiatry 52:139-45. 2011..The study's aim was to examine the prevalence and correlates of neuromotor abnormalities in a sample of neuroleptic-naive psychotic patients...
The meaning of childhood attention-deficit hyperactivity symptoms in patients with a first-episode of schizophrenia-spectrum psychosisVictor Peralta
Psychiatry Section B, Complejo Hospitalario de Navarra, Pamplona, Spain
Schizophr Res 126:28-35. 2011....
Dimensional structure of psychotic symptoms: an item-level analysis of SAPS and SANS symptoms in psychotic disordersV Peralta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Schizophr Res 38:13-26. 1999..The subscale composition of the SAPS and SANS was not supported...
DSM-IV catatonia signs and criteria in first-episode, drug-naive, psychotic patients: psychometric validity and response to antipsychotic medicationVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008 Pamplona, Spain
Schizophr Res 118:168-75. 2010..To examine the prevalence, psychometric validity and response to antipsychotic drugs of DSM-IV catatonia signs and criteria in patients with a first-episode psychotic disorder...
Differentiating primary from secondary negative symptoms in schizophrenia: a study of neuroleptic-naive patients before and after treatmentV Peralta
Psychiatric Unit, Virgen del Camino Hospital, Spain
Am J Psychiatry 157:1461-6. 2000..The study examined the primary versus secondary character of negative symptoms in a group of first-episode, neuroleptic-naive psychotic patients before and after they started neuroleptic treatment...
Motor behavior abnormalities in drug-naïve patients with schizophrenia spectrum disordersVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Mov Disord 25:1068-76. 2010..It is hypothesized that the existence of a differential dopaminergic dysfunction in the nigroestriatal circuitry is responsible for the generation of those motor domains that improve and worsen with antipsychotic drugs...
Motor features in psychotic disorders. I. Factor structure and clinical correlatesV Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, E 31008 Pamplona, Spain
Schizophr Res 47:107-16. 2001..It is concluded that the factor structure of motor disorders and its clinical correlates are rather more complex than generally acknowledged...
Motor features in psychotic disorders. II. Development of diagnostic criteria for catatoniaV Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, E 31008 Pamplona, Spain
Schizophr Res 47:117-26. 2001..In conclusion, patients displaying three or more classical motor signs may be diagnosed with confidence as suffering from a catatonic syndrome...
Characterization of affective domains within the nonaffective psychotic disordersVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008 Pamplona, Spain
Schizophr Res 111:61-9. 2009..To characterize the affective dimensions of psychopathology in patients with a nonaffective psychosis and to examine their validity against a number of external variables...
Duration of untreated psychotic illness: the role of premorbid social support networksVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008, Pamplona, Spain
Soc Psychiatry Psychiatr Epidemiol 40:345-9. 2005..This study aimed at examining the influence of premorbid social networks on the duration of untreated psychotic illness...
Neurological frontal signs and neuropsychological deficits in schizophrenic patientsM J Cuesta
Psychiatric Unit I, Virgen del Camino Hospital, Pamplona, Spain
Schizophr Res 20:15-20. 1996..There was a statistically significant relationships between the frontal signs and the cognitive deficits (mean shared variance was 22%) which persisted after correcting for the influence of age, education, and duration of illness...
Illness duration and neuropsychological impairments in schizophreniaM J Cuesta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Schizophr Res 33:141-50. 1998..These findings suggest the existence of a relationship between cognitive decline in visuomotor and delayed visual memory functions and the length of schizophrenic illness...
Psychopathological dimensions and lack of insight in schizophreniaM J Cuesta
Psychiatric Unit of Virgen del Camino Hospital c Irunlarrea sn, Pamplona, Spain
Psychol Rep 83:895-8. 1998..In addition, when insight was assessed through a multidimensional approach, a variety of relationships with the schizophrenic dimensions were found...
Reappraising insight in psychosis. Multi-scale longitudinal studyM J Cuesta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Br J Psychiatry 177:233-40. 2000..Many patients suffering from psychosis are unaware of their disorder and symptoms...
Effects of olanzapine and other antipsychotics on cognitive function in chronic schizophrenia: a longitudinal studyM J Cuesta
Psychiatric Unit of Virgen del Camino Hospital, Pamplona, Spain
Schizophr Res 48:17-28. 2001..No differential improvements were found in social functioning, verbal fluency, non-verbal domains of memory or visuo-motor abilities...
Integrating psychopathological dimensions in functional psychoses: a hierarchical approachM J Cuesta
Psychiatric Unit I of the Virgen del Camino Hospital, Irunlarrea 4, 31008 Pamplona, Spain
Schizophr Res 52:215-29. 2001..The findings have implications for the design of future studies and for the hierarchical conceptualization of psychopathological dimensions...
Abnormal subjective experiences in schizophrenia: its relationships with neuropsychological disturbances and frontal signsM J Cuesta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Eur Arch Psychiatry Clin Neurosci 246:101-5. 1996..Many significant relationships between subjective experiences and cognitive disturbances persisted after controlling the influence of age, gender, education, lack of insight, neuroleptic doses, and biperidene doses...
Thought disorder in schizophrenia. Testing models through confirmatory factor analysisM J Cuesta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Eur Arch Psychiatry Clin Neurosci 249:55-61. 1999..Thought Disorder dimensions would be potential markers for biological, neurophysiological, and neuropsychological studies of schizophrenic disorder...
Are personality traits associated with cognitive disturbance in psychosis?M J Cuesta
Psychiatric Unit of Virgen del Camino Hospital, C Irunlarrea 4, E 31008 Pamplona, Spain
Schizophr Res 51:109-17. 2001..The goal of the present study was to analyze the relationship between dimensions of personality and cognitive performance in individuals with psychosis...
[Psychosis associated to megacisterna magna]M Langarica
Unidad de Psiquiatria, Hospital Virgen del Camino, Pamplona
An Sist Sanit Navar 28:119-21. 2005..This is the first report of such an association, and it is suggested that both the psychotic disorder and the mega cisterna magna may be the expression of a single underlying neurodevelopment abnormality...
The underlying structure of diagnostic systems of schizophrenia: a comprehensive polydiagnostic approachVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, 31008 Pamplona, Spain
Schizophr Res 79:217-29. 2005..These results are consistent with a unitary and dimensional construct of schizophrenia with no clear "points of rarity" at its boundaries, thus supporting the continuum hypothesis of the psychotic illness...
Psychopathological dimensions in first-episode psychoses. From the trunk to the branches and leavesManuel J Cuesta
Psychiatric Unit of Virgen del Camino Hospital, C Irunlarrea sn, 31008, Pamplona, Spain
Eur Arch Psychiatry Clin Neurosci 253:73-9. 2003..However, few studies have addressed the dilemma of hierarchy within symptoms or dimensions in psychosis...
Insight dimensions and cognitive function in psychosis: a longitudinal studyManuel J Cuesta
Psychiatric Unit of Virgen del Camino Hospital, E 31008 Pamplona, Spain
BMC Psychiatry 6:26. 2006..It has been reported that lack of insight is significantly associated with cognitive disturbance in schizophrenia. This study examines the longitudinal relationships between insight dimensions and cognitive performance in psychosis...
Neurological soft-signs in psychosis: threshold criteria for discriminating normal controls and for predicting cognitive impairmentManuel J Cuesta
Psychiatric Unit, Virgen del Camino Hospital, C Irunlarrea 4, E 31008, Pamplona, Spain
Schizophr Res 58:263-71. 2002..NSS were highly efficient predictors of the presence of severe cognitive impairment related to psychosis. However, their ability to discriminate between individuals with psychosis and normal controls was modest...
Controversies surrounding the diagnosis of schizophrenia and other psychosesManuel J Cuesta
Psychiatric Unit, Virgen del Camino Hospital, C Irunlarrea 4, E 31008 Pamplona, Spain
Expert Rev Neurother 9:1475-86. 2009..These new methods of assessment merging created by the shift toward a dimensional paradigm will be applied in the forthcoming new diagnostic criteria and may allow for a phenome-wide scanning for psychosis...
Psychopathological assessment of schizophrenia: relevance for classificationManuel J Cuesta
Psychiatric Unit, Virgen del Camino Hospital, Irunlarrea 4, Pamplona 31008, Spain
Curr Psychiatry Rep 11:324-31. 2009..Finally, the known limitations of the Kraepelinian dichotomy are summarized, and future problems related to the inclusion of the new dimensional assessment methods in the next psychiatric classifications are described...
Cognitive effectiveness of olanzapine and risperidone in first-episode psychosisManuel J Cuesta
Psychiatric Unit, Virgen del Camino Hospital c Irunlarrea 4, Pamplona E 31008, Spain
Br J Psychiatry 194:439-45. 2009..Cognitive impairment in schizophrenia-spectrum disorders is highly prevalent and notably influences functional outcomes...
[Incidence of psychiatric disorders in patients with fecal incontinence]Mario De Miguel
Servicio de Cirugia General, Hospital Virgen del Camino, Pamplona, Navarra, Spain
Cir Esp 79:241-4. 2006..To evaluate the presence of psychiatric alterations in patients with fecal incontinence...
Premorbid personality and psychopathological dimensions in first-episode psychosisManuel J Cuesta
Psychiatric Unit I, Virgen del Camino Hospital, C Irunlarrea 4, E 31008, Pamplona, Spain
Schizophr Res 58:273-80. 2002..The aim of this study was to examine the relationships between personality and psychopathology in a 'first-episode psychosis' sample using a dimensional approach...
Empirical validation of competing definitions of schizophrenia: a poly-diagnostic study of cognitive impairment in non-affective psychosisManuel J Cuesta
Psychiatric Unit, Virgen del Camino Hospital c Irunlarrea 4, E 31008 Pamplona, Spain
Schizophr Res 95:39-47. 2007..Most diagnostic criteria are still influenced to a large extent by historical and consensus-based perspectives...
A taxometric analysis of schizophrenia symptomsManuel J Cuesta
Psychiatric Unit of Virgen del Camino Hospital, C Irunlarrea 4, Pamplona E 31008, Spain
Psychiatry Res 150:245-53. 2007..The lack of a taxonic structure with symptomatological domains of psychosis suggested the existence of a dimensional solution for schizophrenia symptomatology within psychoses...
Clinical models of schizophrenia: a critical approach to competing conceptionsV Peralta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Psychopathology 33:252-8. 2000..The use of a polydiagnostic approach on the one hand, and a multidimensional approach on the other (the polydiagnostic-multidimensional paradigm), seems to be a promising strategy to better understand the heterogeneity of schizophrenia...
Cycloid psychosis: a clinical and nosological studyVictor Peralta
Psychiatric Unit, Virgen del Camino Hospital, Pamplona, Spain
Psychol Med 33:443-53. 2003..Cycloid psychosis seems to be an heterogeneous condition in that affective and non-affective subgroups can be differentiated...
Current psychopathological issues in psychosis: towards a phenome-wide scanning approachManuel J Cuesta
Schizophr Bull 34:587-90. 2008
Can schizophrenia be diagnosed in the initial prodromal phase?Victor Peralta
Arch Gen Psychiatry 59:664-5. 2002
Interleukin-1beta (IL-1beta) gene and increased risk for the depressive symptom-dimension in schizophrenia spectrum disordersAraceli Rosa
Unitat d Antropologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
Am J Med Genet B Neuropsychiatr Genet 124:10-4. 2004..07). This tendency was not observed in the healthy offspring. Using a multidimensional symptom approach to the diagnosis, the association was confirmed in psychotic patients showing the depressive symptom-dimension (P = 0.02)...
