D A de Luis

Summary

Affiliation: Hospital Universitario
Country: Spain

Publications

  1. ncbi request reprint Effect of a hypocaloric diet in transaminases in nonalcoholic fatty liver disease and obese patients, relation with insulin resistance
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, Valladolid University, C Los perales 16, Simancas 47130, Valladolid, Spain
    Diabetes Res Clin Pract 79:74-8. 2008
  2. ncbi request reprint Relation of Trp64Arg polymorphism of beta 3-adrenergic receptor gene to adipocytokines and fat distribution in obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Hospital Rio Hortega, University of Valladolid, 12D056 0013 Valladolid, Spain
    Ann Nutr Metab 52:267-71. 2008
  3. doi request reprint Influence of Ala54Thr polymorphism of fatty acid-binding protein-2 on clinical results of biliopancreatic diversion
    Daniel A de Luis
    Institute of Endocrinology and Nutrition, Medical School, University of Valladolid, Valladolid, Spain
    Nutrition 24:300-4. 2008
  4. ncbi request reprint Differences in glycaemic status do not predict weight loss in response to hypocaloric diets in obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital U Rio Hortega, University of Valladolid, C Los perales 16, Simancas 47130, Valladolid Spain
    Clin Nutr 25:117-22. 2006
  5. ncbi request reprint [Vegetarian diets; effect on health]
    D De Luis Roman
    Sección de Endocrinología y Nutrición Clínica, Unidad de Apoyo a la nvestigación, Hospital Universitario del Rio Hortega, Valladolid, Espana
    Rev Clin Esp 207:141-3. 2007
  6. ncbi request reprint [Dietary salt in the era of antihypertensive drugs]
    Daniel de Luis
    Sección de Endocrinología y Nutrición Clínica, Unidad de Apoyo a la Investigación, Hospital Universitario Rio Hortega, Instituto de Endocrinología y Nutrición Clínica, Facultad de Medicina de Valladolid, Valladolid, Espana
    Med Clin (Barc) 127:673-5. 2006
  7. doi request reprint C358A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) and insulin resistance in patients with diabetes mellitus type 2
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, C Los perales 16, Simancas 47130, RETICEF RD056 0013, Valladolid, Spain
    Diabetes Res Clin Pract 88:76-80. 2010
  8. ncbi request reprint Effect of two different hypocaloric diets in transaminases and insulin resistance in nonalcoholic fatty liver disease and obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medical School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Nutr Hosp 25:730-5. 2010
  9. doi request reprint Role of G1359A polymorphism of the cannabinoid receptor gene on weight loss and adipocytokines levels after two different hypocaloric diets
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Simancas 47130, Valladolid, Spain
    J Nutr Biochem 23:287-91. 2012
  10. doi request reprint Lys656Asn polymorphism of leptin receptor gene is related with leptin changes after a high monounsaturated fat diet in obese patients
    Daniel A de Luis
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    J Investig Med 61:286-90. 2013

Collaborators

Detail Information

Publications168 found, 100 shown here

  1. ncbi request reprint Effect of a hypocaloric diet in transaminases in nonalcoholic fatty liver disease and obese patients, relation with insulin resistance
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, Valladolid University, C Los perales 16, Simancas 47130, Valladolid, Spain
    Diabetes Res Clin Pract 79:74-8. 2008
    ..The aim of our study was to examine the changes in hypertransaminasemia after weight reduction in obese patients with and without nonalcoholic fatty liver disease (NAFLD) and the relation with insulin resistance...
  2. ncbi request reprint Relation of Trp64Arg polymorphism of beta 3-adrenergic receptor gene to adipocytokines and fat distribution in obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Hospital Rio Hortega, University of Valladolid, 12D056 0013 Valladolid, Spain
    Ann Nutr Metab 52:267-71. 2008
    ..The aim of our study was to investigate the influence of Trp64Arg polymorphism in the beta 3-adrenergic receptor gene on weight, adipocytokines, insulin resistance, and fat distribution in obese patients...
  3. doi request reprint Influence of Ala54Thr polymorphism of fatty acid-binding protein-2 on clinical results of biliopancreatic diversion
    Daniel A de Luis
    Institute of Endocrinology and Nutrition, Medical School, University of Valladolid, Valladolid, Spain
    Nutrition 24:300-4. 2008
    ..The purpose of the present study was to evaluate the fatty acid-binding protein-2 Ala54Thr polymorphism outcomes 1 y after biliopancreatic diversion in morbidly obese patients...
  4. ncbi request reprint Differences in glycaemic status do not predict weight loss in response to hypocaloric diets in obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital U Rio Hortega, University of Valladolid, C Los perales 16, Simancas 47130, Valladolid Spain
    Clin Nutr 25:117-22. 2006
    ..The aim of our study was to detect differences in weigth loss with a hypocaloric diet in obese patients depending on their glycaemic status...
  5. ncbi request reprint [Vegetarian diets; effect on health]
    D De Luis Roman
    Sección de Endocrinología y Nutrición Clínica, Unidad de Apoyo a la nvestigación, Hospital Universitario del Rio Hortega, Valladolid, Espana
    Rev Clin Esp 207:141-3. 2007
    ..The possible theoretical benefits in some diseases has been seen in the medical practice (diabetes mellitus, obesity, cardiovascular risk). However more studies are needed in the case of Parkinson's disease and rheumatoid arthritis...
  6. ncbi request reprint [Dietary salt in the era of antihypertensive drugs]
    Daniel de Luis
    Sección de Endocrinología y Nutrición Clínica, Unidad de Apoyo a la Investigación, Hospital Universitario Rio Hortega, Instituto de Endocrinología y Nutrición Clínica, Facultad de Medicina de Valladolid, Valladolid, Espana
    Med Clin (Barc) 127:673-5. 2006
    ..However this treatment has another piece in the integral approach of this entity with weight reduction programs, suppression of coffe, alcohol and smoking habit, and a right source and type of fats...
  7. doi request reprint C358A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) and insulin resistance in patients with diabetes mellitus type 2
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, C Los perales 16, Simancas 47130, RETICEF RD056 0013, Valladolid, Spain
    Diabetes Res Clin Pract 88:76-80. 2010
    ..The aim of our study was to investigate the relationship of polymorphism (cDNA 385 C-->A) of FAAH gene on obesity parameters in patients with diabetes mellitus type 2...
  8. ncbi request reprint Effect of two different hypocaloric diets in transaminases and insulin resistance in nonalcoholic fatty liver disease and obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medical School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Nutr Hosp 25:730-5. 2010
    ..The aim of our study was to examine the changes in hypertransaminasemia after weight reduction in obese patients with and without NAFLD and the relation with insulin resistance...
  9. doi request reprint Role of G1359A polymorphism of the cannabinoid receptor gene on weight loss and adipocytokines levels after two different hypocaloric diets
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Simancas 47130, Valladolid, Spain
    J Nutr Biochem 23:287-91. 2012
    ..Intervention studies with this polymorphism have not been realized...
  10. doi request reprint Lys656Asn polymorphism of leptin receptor gene is related with leptin changes after a high monounsaturated fat diet in obese patients
    Daniel A de Luis
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    J Investig Med 61:286-90. 2013
    ..The aim of our study was to investigate the influence of Lys656Asn polymorphism in the leptin receptor gene on metabolic response, weight loss, and serum leptin levels to a high monounsaturated fat hypocaloric diet in obese patients...
  11. ncbi request reprint Effect of fatty acid-binding protein 2 Ala54Thr genotype on weight loss and cardiovascular risk factors after a high-polyunsaturated fat diet in obese patients
    Daniel de Luis
    Center of Investigation of Endocrinology and Nutrition, Medicine School, University of Valladolid, Valladolid, Spain
    J Investig Med 60:1194-8. 2012
    ....
  12. ncbi request reprint [Effects on health of soy in menopausic women]
    D A de Luis
    Instituto de Endocrinología y Nutrición, Facultad de Medicina, Unidad de Apoyo a la Investigación, Hospital Universitario Rio Hortega, Valladolid, Espana
    Rev Clin Esp 206:205-7. 2006
    ..However, we could introduce soy and soy derived products within a balanced, varied and adequate diet for these women...
  13. doi request reprint Genetic variation in the cannabinoid receptor gene (CNR1) (G1359A polymorphism) and their influence on anthropometric parameters and metabolic parameters under a high monounsaturated vs. high polyunsaturated fat hypocaloric diets
    Daniel Antonio de Luis
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    J Nutr Biochem 24:1431-5. 2013
    ..Subjects with both genotypes and after a high polyunsaturated fat hypocaloric diet showed a significant improvement of LDL cholesterol, total cholesterol, HOMA-IR and insulin levels. ..
  14. doi request reprint Zinc and copper serum levels of morbidly obese patients before and after biliopancreatic diversion: 4 years of follow-up
    Daniel A de Luis
    University of Valladolid Institute of Endocrinology and Nutrition, Medicine School, Unit of Investigation, and Endocrinology Department Hospital Rio Hortega, C Los perales 16, Simancas, 47130, Valladolid, Spain
    J Gastrointest Surg 15:2178-81. 2011
    ..The aim of our work was to describe the influence of biliopancreatic diversion (BPD) on serum copper and zinc levels during 4 years...
  15. ncbi request reprint Association of -55CT polymorphism of UCP3 gene with fat distribution, cardiovascular risk factors and adipocytokines in patients with Type 2 diabetes mellitus
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    J Endocrinol Invest 35:625-8. 2012
    ..The aim of our study was to investigate the influence of -55CT polymorphism of UCP3 gene on fat mass and adipocytokines in naïve patients with Type 2 diabetes mellitus...
  16. ncbi request reprint Influence of -55CT polymorphism of UCP3 gene on surgical results of biliopancreatic diversion
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School, Unit of Investigation, RD 056 0013, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Obes Surg 20:895-9. 2010
    ..The purpose of the present study was to evaluate the UCP3 promotor (-55C-->T) polymorphism outcomes 1 year after biliopancreatic diversion in morbidly obese patients...
  17. doi request reprint C358A missense polymorphism of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) and visfatin levels in obese females
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Int J Obes (Lond) 34:511-5. 2010
    ..Visfatin has been identified as a protein expressed in visceral adipose tissue with contradictory functions in glucose metabolism...
  18. ncbi request reprint Effects of lifestyle modification on adipocytokine levels in obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega RD056 0013, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 12:33-9. 2008
    ..Adipose tissue is considered an active secretory organ of adipocytokines. The principal aim of our study was to examine the changes in adipocytokines levels after weigth reduction in obese patients...
  19. ncbi request reprint Circulating adipocytokines in obese nondiabetic patients in relationship with cardiovascular risk factors, anthropometry and resting-energy expenditure
    D A de Luis
    Institute of Endocrinology and Nutrition, Medical School and Research Support Unit, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Ann Nutr Metab 51:416-20. 2007
    ..The aim of the present study was to examine the relationship between circulating adipocytokines and cardiovascular risk factors...
  20. doi request reprint Effect of a hypocaloric diet with a commercial formula in weight loss and quality of life in obese patients with chronic osteoarthritis
    D A de Luis
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School, Unit of Investigation, University of Valladolid Valladolid Spain
    Nutr Hosp 27:1648-54. 2012
    ..The aim of our study was to evaluate in patients with obesity and chronic osteoarthritis the impact on quality of life and metabolic control of a dietary intervention with a hypocaloric commercial formula...
  21. doi request reprint Serum visfatin concentrations are related to dietary intake in obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Hospital Rio Hortega, University of Valladolid, Simancas, Spain
    Ann Nutr Metab 57:265-70. 2010
    ..We conducted a cross-sectional study of associations between nutrient intake and serum visfatin concentrations in a group of obese patients...
  22. doi request reprint Relation of leptin and adiponectin with cardiovascular risk factors, intact parathormone, and vitamin D levels in patients with primary hyperparathyroidism
    Daniel Antonio de Luis
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    J Clin Lab Anal 26:398-402. 2012
    ..The aim of the present study was to explore the relationship of leptin and adiponectin levels with cardiovascular risk factors and anthropometric parameters in patients with PHTP with and without metabolic syndrome (MS)...
  23. doi request reprint Clinical results and nutritional consequences of biliopancreatic diversion: three years of follow-up
    D A de Luis
    Institute of Endocrinology and Nutrition, Medical School, Unit of Investigation, Surgical Department, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Ann Nutr Metab 53:234-9. 2008
    ..The aim of our work was to describe clinical results and nutritional complications in morbidly obese patients with biliopancreatic diversion...
  24. ncbi request reprint Effects of C358A polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) on weight loss, adipocytokines levels, and insulin resistance after a high polyunsaturated fat diet in obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, C Los perales 16, Simancas 47130, Valladolid, Spain
    J Endocrinol Invest 36:965-9. 2013
    ..The C385A polymorphism of FAAH gene (rs324420C>A) has been associated with obesity. We investigate the role of this polymorphism on anthropometric and insulin resistance responses to a high polyunsaturated fat hypocaloric diet...
  25. doi request reprint Effects of duodenal-jejunal exclusion on beta cell function and hormonal regulation in Goto-Kakizaki rats
    Daniel de Luis
    Institute of Endocrinology and Nutrition, Medicine School, Unit of Investigation, Surgical Department, and Endocrinology Department, Hospital Rio Hortega, University of Valladolid, C Los perales 16, Simancas 47130, Valladolid, Spain
    Am J Surg 204:242-7. 2012
    ..The aim of our work was to investigate the hormones that control glycemic status and in vitro β-cell function in diabetes mellitus after a duodenal-jejunal exclusion in Goto-Kakizaki rats (Taconic, Denmark)...
  26. doi request reprint Relation of the rs9939609 gene variant in FTO with metabolic syndrome in obese female patients
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid Spain
    J Diabetes Complications 27:346-50. 2013
    ..The aim of our study was to analyze the relationship of the rs9939609 FTO gene polymorphism with metabolic syndrome and its components...
  27. ncbi request reprint Randomized clinical trial with an enteral arginine-enhanced formula in early postsurgical head and neck cancer patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur J Clin Nutr 58:1505-8. 2004
    ..The aim of our study was to investigate whether postoperative nutrition of head and neck cancer patients using an arginine-enhanced formula could improve nutritional variables as well as clinical outcomes...
  28. ncbi request reprint Effects of telmisartan vs olmesartan on metabolic parameters, insulin resistance and adipocytokines in hypertensive obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School, University of Valladolid, Spain
    Nutr Hosp 25:275-9. 2010
    ..Angiotensin II regulates the production of adipokines. The objective was to study the effect of treatment with telmisartan versus olmesartan in hypertensive obese and overweight patients...
  29. ncbi request reprint [Dietary intakes in a group of marihuana smoking patients]
    D A de Luis
    Centro de Investigación en Endocrinología y Nutrición Clínica, Facultad de Medicina, Universidad de Valladolid, Valladolid, Espana
    Nutr Hosp 25:688-91. 2010
    ..Marihuana use has effects on appetite; studies in the literature on this topic area are limited. The aim of our work was to evaluate the dietary intake of marihuana smoking patients...
  30. doi request reprint Relationship of fat distribution with adipokines in patients with acquired immunodeficiency virus infection
    Daniel A de Luis
    Facultad de Medicina, Centro de Investigacion en Endocrinologia y Nutricion Clinica I E N, Unit of Investigation Hospital Universitario Rio Hortega, Valladolid, Spain
    J Clin Lab Anal 26:336-41. 2012
    ..The aim was to examine the relationship of fat distributions with adipokines concentrations in HIV-infected patients...
  31. ncbi request reprint [Systematic review of nutritional support in pressure ulcer]
    D de Luis
    Sección de Endocrinología y Nutrición Clínica Facultad de Medicina Valladolid
    An Med Interna 24:342-5. 2007
    ..However, studies of secondary prevention due to heterogeneity have not let clear conclusions. However, enteral enhanced formula could improve ulcer healing...
  32. ncbi request reprint Basal GLP-1 levels in morbidly obese patients following biliopancreatic diversion surgery
    Daniel de Luis
    Institute of Endocrinology and Nutrition, Medicine School, Unit of Investigation, Surgical Department and Endocrinology Department, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Ann Nutr Metab 61:70-3. 2012
    ..The aim of the present study was to investigate the changes in serum GLP-1 levels 9 months after biliopancreatic diversion in morbidly obese patients without diabetes mellitus...
  33. doi request reprint Basal glucagonlike peptide 1 levels and metabolic syndrome in obese patients
    Daniel A de Luis
    Institute of Endocrinology and Nutrition, Medicine School, Unit of Investigation, University of Valladolid, Valladolid, Spain
    J Investig Med 60:874-7. 2012
    ..The purpose of the present study was to investigate the relationships of basal circulating GLP-1 and metabolic syndrome in obese patients without cardiovascular disease...
  34. ncbi request reprint A randomized clinical trial with two doses of a omega 3 fatty acids oral and arginine enhanced formula in clinical and biochemical parameters of head and neck cancer ambulatory patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 17:1090-4. 2013
    ..The aim was to investigate whether oral ambulatory nutrition of head and neck cancer patients with recent weight loss, using two different doses of an omega 3 fatty acids and arginine enhanced diets could improve nutritional parameters...
  35. ncbi request reprint Role of insulin resistance and adipocytokines on serum alanine aminotransferase in obese patients with type 2 diabetes mellitus
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 17:2059-64. 2013
    ..The aim of our study was to study the association of insulin resistance expressed by HOMA and adipokines in obese type 2 diabetic patients with or without hyper-transaminasemia...
  36. ncbi request reprint Association of anthropometric and biochemical markers with length of stay and mortality in the hospital
    D A de Luis
    Unit of Endocrinology and Nutrition Hospital Rio Hortega and Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 17:1321-5. 2013
    ..Malnutrition is associated with patient outcome, hospital stay and costs. The objective of our study was evaluated the relationship of different anthropometric and biochemical nutritional markers with hospital stance (days) and mortality...
  37. ncbi request reprint [Garlic and cardiovascular risk]
    D A de Luis
    Sección de Endocrinología y Nutrición Clínica, Unidad de Apoyo a la Investigación, Hospital Universitario del Rio Hortega, Valladolid, Spain
    An Med Interna 25:237-40. 2008
    ..However, it is necessary to demonstrate a decrease on cardiovascular events and to elucidate the amount of garlic to obtain benefict effects, most studies are necessary...
  38. ncbi request reprint Relation of visfatin to cardiovascular risk factors and adipocytokines in patients with impaired fasting glucose
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain RD056 0013 RETICEF Electronic address
    Nutrition 29:1300-3. 2013
    ..The aim of the present study was to explore the relation of visfatin concentrations to cardiovascular risk factors and serum adipocytokine concentrations in patients with impaired fasting glucose...
  39. ncbi request reprint Leptin and obesity
    D A de Luis
    Institute of Endocrinology and Nutrition, Medical School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Simancas, Valladolid, Spain
    Minerva Med 100:229-36. 2009
    ..In conclusion, despite the great advances in our knowledge of leptin physiology, many areas of investigation remain. Future research is expected to discover new molecules in the leptin pathway, to treat obesity and its related diseases...
  40. doi request reprint Circulating visfatin in obese non-diabetic patients in relation to cardiovascular risk factors, insulin resistance, and adipocytokines: a contradictory piece of the puzzle
    Daniel A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Nutrition 26:1130-3. 2010
    ..The aim of the present study was to explore the relation of circulating visfatin to insulin resistance, cardiovascular risk factors, anthropometry, and adipocytokines in obese patients without diabetes mellitus...
  41. doi request reprint Influence of Trp64Arg polymorphism of beta 3-adrenoreceptor gene on insulin resistance, adipocytokines and weight loss secondary to two hypocaloric diets
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Ann Nutr Metab 54:104-10. 2009
    ..To investigate the influence of the Trp64Arg polymorphism in the beta 3-adrenoreceptor gene on adipocytokines, insulin resistance and weight loss secondary to a low fat versus a low carbohydrate diet...
  42. doi request reprint Effects of C358A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase on weight loss after a hypocaloric diet
    Daniel Antonio de Luis
    Center of Investigation in Endocrinology and Clinical Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid Spain
    Metabolism 60:730-4. 2011
    ..61 mg/dL) levels. The A allele at rs324420 in the FAAH gene was associated with larger improvements in glucose, total cholesterol, low-density lipoprotein cholesterol, body mass, and waist circumference after a dietary intervention...
  43. ncbi request reprint Relationship of insulin resistance and adipocytokines on serum alanine aminotransferase in presurgical morbid obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 13:413-8. 2009
    ..The aim of this research was to study the influence of insulin resistance and adipocytokines in presurgical morbid obese patients on elevated serum alanine aminotransferase (ALT) as an indicator of NAFLD...
  44. ncbi request reprint A randomized double-blind clinical trial with two different doses of arginine enhanced enteral nutrition in postsurgical cancer patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 14:941-5. 2010
    ..3 g per day) could improve nutritional variables as well as clinical outcome...
  45. doi request reprint Effects of C358A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase on weight loss and cardiovascular risk factors 1 year after biliopancreatic diversion surgery
    D A de Luis
    Center of Investigation of Endocrinology and Clinical Nutrition, University of Valladolid Medical School and Unit of Investigation, Hospital Rio Hortega, Valladolid, Spain
    Surg Obes Relat Dis 6:516-20. 2010
    ..We investigated the role of the polymorphism (C358A) of the fatty acid amide hydrolase gene on the clinical outcomes 1 year after biliopancreatic diversion in morbidly obese patients...
  46. doi request reprint Visfatin levels in female, morbid, nondiabetic obese patients after biliopancreatic diversion surgery
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School, Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Surg Obes Relat Dis 7:195-8. 2011
    ..The purpose of the present study was to investigate the changes in serum visfatin levels after biliopancreatic diversion and the association of the changes observed with other parameters in morbidly nondiabetic obese women...
  47. ncbi request reprint Effect on quality of life with a new insulin injection device in elderly patients with diabetes mellitus type 2
    D A de Luis
    Instituto de Endocrinología y Nutrición, Facultad de Medicina y Unidad de Apoyo a la Investigación, Hospital Rio Hortega, Universidad de Valladolid, C perales 16, Valladolid 47130, Spain
    J Diabetes Complications 18:216-9. 2004
    ..The aim was to investigate the efficacy, safety, and satisfaction of a new insulin injection device in elderly subjects with type 2 diabetes on suboptimal glycemic control with two doses of insulin NPH alone...
  48. ncbi request reprint The rs9939609 gene variant in FTO modified the metabolic response of weight loss after a 3-month intervention with a hypocaloric diet
    Daniel Antonio de Luis
    Center of Investigation of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    J Investig Med 61:22-6. 2013
    ..Common polymorphisms in the fat mass and obesity associated gene (FTO) have been linked to obesity in some populations. Nevertheless, the role of FTO variants on body weight response after dietary intervention remains equivocal...
  49. ncbi request reprint [Isolated dietary counselling program versus supplement and dietary counselling in patients with human immunodeficiency virus infection]
    Daniel de Luis
    Sección de Endocrinología y Nutrición Clínica Unidad de Apoyo a la Investigación Hospital del Río Hortega Valladolid Servicio de Medicina Interna Instituto de Endocrinología y Nutrición IEN Valladolid Spain
    Med Clin (Barc) 120:565-7. 2003
    ....
  50. ncbi request reprint Effect of a high monounsaturated vs high polyunsaturated fat hypocaloric diets in nonalcoholic fatty liver disease
    R Aller
    Institute of Endocrinology and Nutrition, Medicine School and Deparment of Endocrinology and Nutrition, Hospital Clinico Universitario, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 18:1041-7. 2014
    ..We decide to examine the changes in hyperaminotransferasemia after weight reduction in obese patients with and without NAFLD secondary to a high monounsaturated fat vs. a high polyunsaturated fat hypocaloric diets...
  51. ncbi request reprint [Roles of rs 6923761 gene variant in glucagon-like Peptide 1 receptor on weight, cardiovascular risk factor and serum adipokine levels in morbid obese patients]
    Daniel Antonio de Luis
    Center of Investigation of Endocrinology and Nutrition Medicine School Svo de Endocrinología y Nutrición Hospital Clinico Universitario University of Valladolid Valladolid Spain
    Nutr Hosp 29:889-93. 2014
    ..Nevertheless, the role of GLP-1 variants on body weight, cardiovascular risk factors and adipokines remains unclear in obese patients...
  52. ncbi request reprint [Modified texture diet and useful in patients with nutritional risk]
    Daniel A de Luis
    Centro de Investigación de Endocrinología y Nutrición Clínica Facultad de Medicina
    Nutr Hosp 29:751-9. 2014
    ..Sometimes it is necessary to use artificial products to achieve different desired textures and precooked dishes, too...
  53. ncbi request reprint Relation of -55CT polymorphism of UCP3 gene with weight loss and metabolic changes after a high monounsaturated fat diet in obese non diabetic patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 17:2810-5. 2013
    ..The aim of our study was to investigate the influence of -55CT polymorphism of UCP3 gene on metabolic response, weight loss and serum adipokine levels to a high monounsaturated fat hypocaloric diet in obese patients...
  54. ncbi request reprint [Blood glucose and insulin responses to two hypocaloric enteral formulas in patients with diabetes mellitus type 2]
    D A de Luis
    Center of Investigation of Endocrinology and Nutrition, Medicine School and Unit of Investigation Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Nutr Hosp 28:600-96. 2013
    ....
  55. doi request reprint Double blind randomized clinical trial controlled by placebo with a fos enriched cookie on saciety and cardiovascular risk factors in obese patients
    D A de Luis
    Facultad de Medicina y Unidad de Apoyo a la Investigación, Instituto de Endocrinología y Nutrición, Hospital Rio Hortega, Universidad de Valladolid, Simancas, Valladolid
    Nutr Hosp 28:78-85. 2013
    ..It is essential to determine which snack foods are most affective for appetite control. The objective of the current study was to assess the responses of two different cookies on satiety and cardiovascular risk factors...
  56. doi request reprint Experience over 12 years with home enteral nutrition in a healthcare area of Spain
    D A de Luis
    Unit of Endocrinology and Nutrition, Hospital University Rio Hortega, Institute of Endocrinology and Nutrition, Medicine School, Valladolid, Spain
    J Hum Nutr Diet 26:39-44. 2013
    ..The present study aimed to analyse the incidence and characteristics of a cohort of patients on home enteral nutrition (HEN) over 12 years...
  57. doi request reprint Role of G308 promoter variant of tumor necrosis factor alpha gene on weight loss and metabolic parameters after a high monounsaturated versus a high polyunsaturated fat hypocaloric diets
    Daniel A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Med Clin (Barc) 141:189-93. 2013
    ....
  58. ncbi request reprint A randomized clinical trial with two doses of an enteral diabetes-specific suplements in elderly patients with diabetes mellitus type 2
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 17:1626-30. 2013
    ..The aim of our study was to investigate whether two different daily doses of a high monounsaturated fatty acid (MUFA) specific diabetes enteral formula could improve nutritional variables as well as metabolic parameters...
  59. doi request reprint Genetic variation in the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) and their influence on weight loss and insulin resistance under a high monounsaturated fat hypocaloric diet
    Daniel de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, C Los perales 16, Simancas 47130, Valladolid, Spain
    J Diabetes Complications 27:235-9. 2013
    ..The C385A polymorphism of FAAH gene (rs324420C>A) has been associated with obesity. We investigate the role of this polymorphism on anthropometric and metabolic responses after an enriched monounsaturated fat hypocaloric diet...
  60. doi request reprint Micronutrient status in morbidly obese women before bariatric surgery
    Daniel A de Luis
    Institute of Endocrinology and Nutrition, University of Valladolid Medicine School, Valladolid, Spain
    Surg Obes Relat Dis 9:323-7. 2013
    ..The aim of our work was to describe the micronutrient status in obese women before surgery at a university hospital...
  61. doi request reprint [Insulin analogues: modifications in the structure, molecular and metabolic consequences]
    D A de Luis
    Facultad de Medicina, Universidad de Valladolid, Valladolid, Espana
    Semergen 39:34-40. 2013
    ..In addition we discussed the main controversies of the use of these insulin analogues. In particular, those related with the risk of cancer and retinopathy, and their use in pregnant women...
  62. doi request reprint [Relation of -55CT polymorphism of UCP3 gene with weight loss and metabolic changes after a high polyunsaturated fat diet in obese patients]
    D A de Luis
    Centro de Investigación de Endocrinología y Nutrición Clínica, Facultad de Medicina, Hospital Rio Hortega, Universidad de Valladolid, Valladolid, Espana
    Nutr Hosp 27:1190-5. 2012
    ..The aim of our study was to investigate the influence of -55CT polymorphism of UCP3 gene in the metabolic response, weight loss and serum levels of adipokines following a hypocaloric diet rich in polyunsaturated fat in obese patients...
  63. doi request reprint [Relation of the rs9939609 gene variant in FTO with cardiovascular risk factor and serum adipokine levels in morbid obese patients]
    D A de Luis
    Centro de Investigación de Endocrinología y Nutrición Clínica, Facultad de Medicina, Hospital Río Ortega, Universidad de Valladolid, Valladolid, Espana
    Nutr Hosp 27:1184-9. 2012
    ..The aim of our study was to analyze the relationship of the rs9939609 FTO gene polymorphism on body weight, cardiovascular risk factors and serum adipokine levels in morbid obese patients...
  64. doi request reprint Evaluation of weight loss and adipocytokines levels after two hypocaloric diets with different macronutrient distribution in obese subjects with rs9939609 gene variant
    Daniel Antonio de Luis
    Center of Investigation of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Diabetes Metab Res Rev 28:663-8. 2012
    ..Common polymorphisms of the fat mass and obesity associated gene (FTO) have been linked to obesity in some populations. One of these genetic variants (rs9939609) has been related to an increased risk of obesity...
  65. ncbi request reprint [Perioperatory artificial nutrition]
    D A de Luis
    Instituto de Endocrinología y Nutrición, Facultad de Medicina, Unidad de Apoyo a la Investigación, Hospital Clínico Universitario Río Hortega, Valladolid
    An Med Interna 25:297-300. 2008
    ..New research areas have been explored in this topic area, carbohydrate utility in presurgical patients and probiotic in enteral formulas...
  66. ncbi request reprint [Influence of a W3 fatty acids oral enhanced formula in clinical and biochemical parameters of head and neck cancer ambulatory patients]
    D A de Luis
    Instituto de Endocrinología y Nutrición, Facultad de Medicina y Unidad de Investigación, Hospital Rio Hortega, Valladolid
    An Med Interna 25:275-8. 2008
    ....
  67. ncbi request reprint [Relation between intake of omega 3 fatty acids and CD4 count in patients with HIV infection: a transversal study]
    D A de Luis
    Sección de Endocrinología y Nutrición Clínica, Hospital del Rio Hortega, Valladolid
    An Med Interna 22:323-5. 2005
    ..These agents could develop a main role in patients with HIV infection. The aim of our study was to analyse the relation between polyunsaturated fatty acid intake and CD4 count in HIV infected patients...
  68. ncbi request reprint Experience of 6 years with home enteral nutrition in an area of Spain
    D A de Luis
    Secc de Endocrinologia Y Nutricion Clinica Hospital U Rio Hortega, Valladolid, Spain
    Eur J Clin Nutr 60:553-7. 2006
    ..The aim of our study was to analyze incidence and characteristics of a cohort of patients on HEN during 6 years, after our previous pilot study of 3 years...
  69. doi request reprint Metabolic syndrome and ALA54THR polymorphism of fatty acid-binding protein 2 in obese patients
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Simancas 47130, Valladolid, Spain
    Metabolism 60:664-8. 2011
    ..No differences in anthropometric and biochemical parameters were detected between genotypes in the same group of MS. The finding of our study is the lack of association of the Thr54/Ala54 and Thr54/Thr54 FABP2 genotypes with MS...
  70. doi request reprint Lack of association of serum resistin levels with metabolic syndrome criteria in obese female patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid Spain
    Clin Biochem 44:1280-3. 2011
    ..As unclear data of resistin relation with metabolic syndrome has been published, we decide to investigate the association between metabolic syndrome and resistin levels in female obese subjects...
  71. ncbi request reprint [Antioxidant and fat intake in patients with polinic asthma]
    Daniel Antonio de Luis
    Instituto de Endocrinología y Nutrición, Facultad de Medicina, Hospital Rio Hortega, Universidad de Valladolid, Valladolid, Espana
    Med Clin (Barc) 121:653-4. 2003
    ..The aim of our work was to evaluate the dietary intake of patients with asthma...
  72. ncbi request reprint Resting energy expenditure, cardiovascular risk factors and insulin resistance in obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medical School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Spain
    Ann Nutr Metab 49:381-5. 2005
    ..The aim of our study was to determine whether energy expenditure modified by increasing body mass over the wide range of body mass index (BMI) was related to insulin resistance, cardiovascular risk factors and dietary intakes...
  73. doi request reprint Influence of lys656asn polymorphism of leptin receptor gene on surgical results of biliopancreatic diversion
    Daniel Antonio de Luis
    Unit of Investigation and Endocrinology Department, Hospital Rio Hortega, Institute of Endocrinology and Nutrition, Medicine School, University of Valladolid, Valladolid 47130, Spain
    J Gastrointest Surg 14:899-903. 2010
    ..The purpose of the present study was to evaluate Lys656Asn polymorphism of leptin receptor gene on outcomes 1 year after biliopancreatic diversion...
  74. ncbi request reprint Tissue electric properties in head and neck cancer patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Unidad de Apoyo a la Investigación, H Universitario Río Hortega, Sv Digestive, H Valladolid, Spain
    Ann Nutr Metab 50:7-10. 2006
    ..The phase angle is easy to obtain. The aim of our study was to investigate in a case-control study the utility of phase angle and other impedance parameters in a population of male patients with head and neck cancer...
  75. ncbi request reprint Immunoenhanced enteral nutrition, effect on inflammatory markers in head and neck cancer patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation Hospital Rio Hortega, Spain
    Eur J Clin Nutr 59:145-7. 2005
    ..In conclusion, both formulas improved IL-6 and CRP levels. Further studies are needed to determine whether type of formula is the key in these patients or genetic background play a main role in inflammatory response...
  76. ncbi request reprint Polymorphism Trp64Arg of beta 3 adrenoreceptor gene: allelic frequencies and influence on insulin resistance in a multicenter study of Castilla-León
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School, University of Valladolid, Spain
    Nutr Hosp 25:299-303. 2010
    ..The aim of our study was to investigate the influence of Trp64Arg polymorphism in the Beta3AR gene on insulin resistance in obese patients and the allelic distribution of this polymorphismin a geographic area of Spain...
  77. doi request reprint Polymorphism Ala54Thr of fatty acid-binding protein 2: Allelic frequencies and influence on cardiovascular risk factors in a multicenter study of Castilla y Leon
    D A de Luis
    Institute of Endocrinology and Nutrition, Hospital Rio Hortega, University of Valladolid, Spain
    Ann Nutr Metab 57:163-8. 2010
    ..A transition of guanin to alanin at codon 54 of the fatty acid-binding protein 2 gene (FABP2) results in an amino acid substitution (Ala54 to Thr54). This polymorphism was associated with some cardiovascular risk factors...
  78. ncbi request reprint Interaction of -55CT polymorphism of UCP3 gene with Trp64Arg polymorphism of beta3adrenoreceptor gene on insulin resistance in obese patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain RD056 0001 3RETICEF
    Eur Rev Med Pharmacol Sci 16:610-6. 2012
    ....
  79. doi request reprint The effects of two different hypocaloric diets on glucagon-like peptide 1 in obese adults, relation with insulin response after weight loss
    Daniel A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    J Diabetes Complications 23:239-43. 2009
    ..Few studies have investigated the effect of type of diets on GLP-1 concentrations. The aim of this study was to compare the effect of two diets on circulating GLP-1 levels and the relation with insulin response after weight loss...
  80. ncbi request reprint A randomized clinical trial with two enteral diabetes-specific supplements in patients with diabetes mellitus type 2: metabolic effects
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 12:261-6. 2008
    ..A diabetes-specific supplement with lower fat percentage than the first improved weight and protein levels without significative metabolic effects...
  81. ncbi request reprint Influence of hormonal status and oral intake on phase angle in HIV-infected men
    Daniel A de Luis
    Institute of Endocrinology and Nutrition, Section on Endocrinology and Nutrition, Unidad de Apoyo a la Investigación, H Universitario Río Hortega, Valladolid, Spain
    Nutrition 20:731-4. 2004
    ..In the literature, this angle is the single best predictor of survival in patients with the human immunodeficiency virus (HIV). The aim of our study was to detect nutritional and biochemical parameters that influence the phase angle...
  82. ncbi request reprint Relation between total homocysteine levels and beer intake in patients with diabetes mellitus Type 2
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Hospital Rio Hortega and University of Valladolid Medical School, Valladolid, Spain
    Ann Nutr Metab 47:119-23. 2003
    ..The aim of our study was to investigate the relation between macro- and micronutrient intakes and homocysteine levels in a population having diabetes type 2...
  83. doi request reprint Changes of ghrelin and leptin in response to hypocaloric diet in obese patients
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, RD 056 0013RETICF, Valladolid, Spain
    Nutrition 24:162-6. 2008
    ..The aim of the present study was to determine whether subjects who lose significant weight experience changes in circulating ghrelin and leptin levels...
  84. ncbi request reprint Influence of insulin resistance and adipocytokines on elevated serum alanine aminotransferase in obese patients
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Arch Med Res 39:110-4. 2008
    ..The aim of our study was to study the influence of insulin resistance and adipocytokines in obese patients on elevated serum alanine aminotransferase (ALT)...
  85. ncbi request reprint Effects of a low-fat versus a low-carbohydrate diet on adipocytokines in obese adults
    D A de Luis
    Institute of Endocrinology and Nutrition, Medical School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Horm Res 67:296-300. 2007
    ..The aim of our study was to determine whether different diets would have different weight loss effects and to examine the changes in adipocytokine levels...
  86. ncbi request reprint Resting energy expenditure and insulin resitance in obese patients, differences in women and men
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 10:285-9. 2006
    ..There is little research about the relation of REE and insulin resistance with gender. The aim of our work was to study gender differences in REE and insulin resistance in obese patients...
  87. ncbi request reprint Influence of G308A polymorphism of tumor necrosis factor-alpha gene on inflammatory markers in postsurgical head and neck cancer patients with early enteral nutrition
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Nutrition 23:529-32. 2007
    ..Our study evaluated the effect of G308A polymorphism of the tumor necrosis factor-alpha (TNF-alpha) gene on inflammatory markers in patients after surgery for head and neck cancer who received early enteral nutrition...
  88. ncbi request reprint A randomized clinical trial with two omega 3 fatty acid enhanced oral supplements in head and neck cancer ambulatory patients
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 12:177-81. 2008
    ..In conclusion, at dose taken, omega 3 enhanced formulas with different omega3/omega6 ratios improved serum protein concentrations in ambulatory postoperative head and neck cancer patients with good tolerance...
  89. doi request reprint Relationship of -55C/T polymorphism of uncoupling protein 3 (UCP3) gene with metabolic syndrome by ATP III classification
    Daniel Antonio de Luis
    Center of Investigation of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, C Los perales 16, Simancas, Valladolid, Spain
    J Clin Lab Anal 26:272-8. 2012
    ..The aim of our study was to investigate the association of -55C/T polymorphism of UCP3 gene with MS...
  90. doi request reprint Relationship among metabolic syndrome, C358A polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) and insulin resistance
    D A de Luis
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    J Diabetes Complications 26:328-32. 2012
    ..It has been demonstrated that the polymorphism 385 C/A of FAAH (fatty acid amide hydrolase) was associated with obesity and metabolic disorders...
  91. doi request reprint Effects of RS9939609 gene variant in FTO gene on weight loss and cardiovascular risk factors after biliopancreatic diversion surgery
    Daniel Antonio de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    J Gastrointest Surg 16:1194-8. 2012
    ..Only two studies have investigated the effect of FTO variants on weight loss of morbid obese patients undergoing bariatric surgery with contradictory results...
  92. ncbi request reprint Allelic frequency of G380A polymorphism of tumor necrosis factor alpha gene and relation with cardiovascular risk factors and adipocytokines in obese patients
    D A de Luis
    Center of Investigation of Endocrinology and Nutrition, Medicine School and Unit of Investigation, University of Valladolid, Spain
    Nutr Hosp 26:711-5. 2011
    ..The aim of our study was to investigate the allelic frequency of the G308A polymorphism in the TNF alpha gene and the influence of G308A this polymorphism on cardiovascular risk factors and adipokine levels in obese patients...
  93. ncbi request reprint Double blind randomized clinical trial controlled by placebo with an alpha linoleic acid and prebiotic enriched cookie on risk cardiovascular factor in obese patients
    D A de Luis
    Instituto de Endocrinología y Nutrición, Facultad de Medicina y Unidad de Apoyo a la Investigación Hospital Río Hortega, Universidad de Valladolid, Valladolid, Espana
    Nutr Hosp 26:827-33. 2011
    ..The aim of our study was to evaluate the response of the cardiovascular risk profile in obese patients after inclusion in the diet of an ALA, FOS and inulin enriched-cookie...
  94. ncbi request reprint Lack of effect of a moderate hypocaloric diet on visfatin levels in morbid obese patients: relationship with insulin resistance
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 14:1031-6. 2010
    ..The insulin-mimetic adipocytokine visfatin has been related to obesity. The aim of this study was to examine whether weight loss could change visfatin concentrations in morbidly obese patients and its relationship with insulin resistance...
  95. doi request reprint Resistin levels in morbid obese patients following the biliopancreatic diversion surgery
    D A de Luis
    Center of Investigation of Endocrinology and Nutrition, Medicine School, Unit of Investigation, Surgical Department, and Endocrinology Department, Hospital Rio Hortega, University of Valladolid, Valladolid, Spain
    Horm Metab Res 43:205-8. 2011
    ..68, p < 0.01) and fat mass (r = 0.65, p < 0.05). Resistin concentrations did not change after massive weight loss with biliopancreatic diversion in morbid obese patients without diabetes mellitus...
  96. ncbi request reprint [Hypothyroidism: clinical and economical implications in a health area]
    D De Luis Roman
    Unidad de Endocrinología y Nutrición Clínica, Unidad de Apoyo a la Investigación, Hospital del Rio Hortega, Instituto de Endocrinología y Nutrición, Facultad de Medicina, Valladolid
    An Med Interna 20:127-33. 2003
    ..To analyze the clinical, biochemical and epidemiological characteristics in patients with hypothyroidism, substitutive dose and annual direct costs, in a health area...
  97. ncbi request reprint [Home enteral nutrition: analysis of efficiency in a Health District]
    D De Luis Roman
    Sección de Endocrinología y Nutrición Clínica Hospital del Río Hortega Valladolid Instituto de Endocrinología y Nutrición Clínica Facultad de Medicina Valladolid Spain
    Rev Clin Esp 203:317-20. 2003
    ..The objective of our study was to carry out a direct costs analysis of household enteral nutrition using both the biochemical and nutritional monitoring values of the nutritional state as a point of reference...
  98. ncbi request reprint Effects of olmesartan vs irbesartan on metabolic parameters and visfatin in hypertensive obese women
    D A de Luis
    Institute of Endocrinology and Nutrition, Medicine School and Unit of Investigation, Hospital Rio Hortega RD 056 0013 RETICEF, University of Valladolid, Valladolid, Spain
    Eur Rev Med Pharmacol Sci 14:759-63. 2010
    ..Angiotensin II regulates the production of adipokines. The objective was to study the effect of treatment with irbesartan versus olmesartan in obese hypertensive women...
  99. ncbi request reprint Interaction between tumor necrosis factor-α gene -308G/A promoter and leptin receptor gene Lys656Asn single-nucleotide polymorphisms: effect on serum leptin concentrations
    D A de Luis
    Institute of Endocrinology and Nutrition, School of Medicine and Unit of Investigation, Hospital Rio Hortega, University of Valladolid, C Los perales 16, Simancas, Spain
    Ann Nutr Metab 57:89-94. 2010
    ....
  100. ncbi request reprint [Usefulness of oral nutritional supplements]
    D De Luis Roman
    Sección de Endocrinología y Nutrición Clínica Hospital del Río Hortega Valladolid Spain
    Rev Clin Esp 202:602-3. 2002
  101. ncbi request reprint Circulating adipocytokines in morbid obese patients, relation with cardiovascular risk factors and anthropometric parameters
    D A de Luis
    Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School, University of Valladolid, Valladolid, Spain
    Nutr Hosp 26:91-6. 2011
    ..The aim of the present study was to explore the relation of circulating adipocytokines with cardiovascular risk and anthropometric parameters in morbid obese patients...