Gavin Lucas

Summary

Affiliation: Hospital del Mar
Country: Spain

Publications

  1. pmc Post-genomic update on a classical candidate gene for coronary artery disease: ESR1
    Gavin Lucas
    Cardiovascular Epidemiology and Genetics Group, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Circ Cardiovasc Genet 4:647-54. 2011
  2. pmc Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction
    Gavin Lucas
    Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain
    PLoS ONE 7:e41730. 2012
  3. pmc Assessment of the value of a genetic risk score in improving the estimation of coronary risk
    Carla Lluís-Ganella
    Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain
    Atherosclerosis 222:456-63. 2012
  4. doi Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel
    Michel Zabalza
    Cardiovascular Epidemiology and Genetics, Institut de Recerca Hospital del Mar, Dr Aiguader 88, Barcelona, Catalonia, Spain
    Heart 98:100-8. 2012
  5. doi A gain-of-function SNP in TRPC4 cation channel protects against myocardial infarction
    Carole Jung
    Laboratory of Molecular Physiology and Channelopathies, Universitat Pompeu Fabra, Parc de Recerca Biomedica de Barcelona, C Dr Aiguader 88, Barcelona, Spain
    Cardiovasc Res 91:465-71. 2011
  6. ncbi Additive effect of multiple genetic variants on the risk of coronary artery disease
    Carla Lluís-Ganella
    Grupo de Epidemiología y Genética Cardiovascular ULEC, Institut Municipal d Investigacio Medica, Hospital del Mar, Barcelona, Espana
    Rev Esp Cardiol 63:925-33. 2010
  7. doi Qualitative assessment of previous evidence and an updated meta-analysis confirms lack of association between the ESR1 rs2234693 (PvuII) variant and coronary heart disease in men and women
    Carla Lluís-Ganella
    Grup d Epidemiologia i Genètica Cardiovascular EGEC ULEC, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, Barcelona, Spain
    Atherosclerosis 207:480-6. 2009
  8. pmc DNA Isolation Method Is a Source of Global DNA Methylation Variability Measured with LUMA. Experimental Analysis and a Systematic Review
    Carolina Soriano-Tárraga
    Neurovascular Research Group Neurology Department Institut Hospital del Mar d Investigacions Mèdiques IMIM, Barcelona, Spain
    PLoS ONE 8:e60750. 2013
  9. pmc CNVassoc: Association analysis of CNV data using R
    Isaac Subirana
    CIBER Epidemiology and Public Health, Barcelona, Spain
    BMC Med Genomics 4:47. 2011

Collaborators

Detail Information

Publications9

  1. pmc Post-genomic update on a classical candidate gene for coronary artery disease: ESR1
    Gavin Lucas
    Cardiovascular Epidemiology and Genetics Group, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Circ Cardiovasc Genet 4:647-54. 2011
    ..Genetic association studies of the gene-encoding Estrogen Receptor α (ESR1) have shown conflicting results, although only a limited range of variation in the gene has been investigated...
  2. pmc Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction
    Gavin Lucas
    Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain
    PLoS ONE 7:e41730. 2012
    ..3-2.0, depending on allele frequency and interaction model)...
  3. pmc Assessment of the value of a genetic risk score in improving the estimation of coronary risk
    Carla Lluís-Ganella
    Cardiovascular Epidemiology and Genetics, IMIM, Barcelona, Spain
    Atherosclerosis 222:456-63. 2012
    ....
  4. doi Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel
    Michel Zabalza
    Cardiovascular Epidemiology and Genetics, Institut de Recerca Hospital del Mar, Dr Aiguader 88, Barcelona, Catalonia, Spain
    Heart 98:100-8. 2012
    ..A random-effects model was used to summarise the results. In the presence of between-study heterogeneity, a meta-regression analysis was performed to identify study characteristics explaining this heterogeneity...
  5. doi A gain-of-function SNP in TRPC4 cation channel protects against myocardial infarction
    Carole Jung
    Laboratory of Molecular Physiology and Channelopathies, Universitat Pompeu Fabra, Parc de Recerca Biomedica de Barcelona, C Dr Aiguader 88, Barcelona, Spain
    Cardiovasc Res 91:465-71. 2011
    ..This study sought to identify single-nucleotide polymorphisms (SNPs) in the TRPC4 gene that are associated with myocardial infarction (MI)...
  6. ncbi Additive effect of multiple genetic variants on the risk of coronary artery disease
    Carla Lluís-Ganella
    Grupo de Epidemiología y Genética Cardiovascular ULEC, Institut Municipal d Investigacio Medica, Hospital del Mar, Barcelona, Espana
    Rev Esp Cardiol 63:925-33. 2010
    ..The objective of this study was to evaluate the magnitude of the association between a genetic risk score, which is based on the accumulated number of risk alleles in all genetic variants of interest, and the presence of CAD...
  7. doi Qualitative assessment of previous evidence and an updated meta-analysis confirms lack of association between the ESR1 rs2234693 (PvuII) variant and coronary heart disease in men and women
    Carla Lluís-Ganella
    Grup d Epidemiologia i Genètica Cardiovascular EGEC ULEC, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, Barcelona, Spain
    Atherosclerosis 207:480-6. 2009
    ..The objectives of this study were to perform a qualitative and a quantitative assessment of all evidence to date regarding this association...
  8. pmc DNA Isolation Method Is a Source of Global DNA Methylation Variability Measured with LUMA. Experimental Analysis and a Systematic Review
    Carolina Soriano-Tárraga
    Neurovascular Research Group Neurology Department Institut Hospital del Mar d Investigacions Mèdiques IMIM, Barcelona, Spain
    PLoS ONE 8:e60750. 2013
    ..DNA isolation method is a source of GDM variability measured with LUMA. To avoid possible bias, the method used should be reported and taken into account in future DNA methylation studies...
  9. pmc CNVassoc: Association analysis of CNV data using R
    Isaac Subirana
    CIBER Epidemiology and Public Health, Barcelona, Spain
    BMC Med Genomics 4:47. 2011
    ..The package includes functions for inferring copy number (CNV genotype calling), but can also accept copy number data generated by other algorithms (e.g. CANARY, CGHcall, IMPUTE)...