Roser Lopez-Alemany

Summary

Affiliation: Hospital Duran i Reynals
Country: Spain

Publications

  1. ncbi Inhibition of cell surface mediated plasminogen activation by a monoclonal antibody against alpha-Enolase
    Roser Lopez-Alemany
    Centre d Oncologia Molecular C O M, Institut de Recerca Oncolgica IRO, Barcelona, Spain
    Am J Hematol 72:234-42. 2003
  2. ncbi Alpha-enolase plasminogen receptor in myogenesis
    Roser Lopez-Alemany
    Institut de Recerca Oncologica, Centre d Oncologia Molecular, L Hospitalet de Llobregat, Barcelona, Spain
    Front Biosci 10:30-6. 2005
  3. ncbi Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo
    Monica Suelves
    Centre d Oncologia Molecular, Institut de Recerca Oncologica, Barcelona, Spain
    Blood 99:2835-44. 2002
  4. ncbi Plasmin generation dependent on alpha-enolase-type plasminogen receptor is required for myogenesis
    Roser Lopez-Alemany
    Institut de Recerca Oncològia, Centre d Oncologia Molecular, L Hospitalet de Llobregat, Barcelona, Spain
    Thromb Haemost 90:724-33. 2003
  5. pmc Requirement of plasminogen binding to its cell-surface receptor α-enolase for efficient regeneration of normal and dystrophic skeletal muscle
    Angels Diaz-Ramos
    IDIBELL Institut d Investigacions Biomèdiques de Bellvitge, Biological Clues of the Invasive and Metastatic Phenotype Research Group, L Hospitalet de Llobregat, Barcelona, Spain
    PLoS ONE 7:e50477. 2012
  6. pmc uPA deficiency exacerbates muscular dystrophy in MDX mice
    Monica Suelves
    Program on Differentiation and Cancer, Center for Genomic Regulation, E 08003, Barcelona, Spain
    J Cell Biol 178:1039-51. 2007
  7. ncbi The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1)
    Monica Suelves
    Program on Differentiation and Cancer, Center for Genomic Regulation, Barcelona, Spain
    Front Biosci 10:2978-85. 2005
  8. pmc α-Enolase, a multifunctional protein: its role on pathophysiological situations
    Angels Diaz-Ramos
    Biological Clues of the Invasive and Metastatic Phenotype Research Group, IDIBELL Institut d Investigacions Biomèdiques de Bellvitge, L Hospitalet de Llobregat, 08908 Barcelona, Spain
    J Biomed Biotechnol 2012:156795. 2012
  9. ncbi Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with alphavbeta3 integrin for vitronectin binding
    Roser Lopez-Alemany
    Institut de Recerca Oncològica IRO, Centre d Oncologia Molecular, L Hospitalet de Llobregat, Barcelona, Spain
    Eur J Biochem 270:814-21. 2003

Collaborators

Detail Information

Publications9

  1. ncbi Inhibition of cell surface mediated plasminogen activation by a monoclonal antibody against alpha-Enolase
    Roser Lopez-Alemany
    Centre d Oncologia Molecular C O M, Institut de Recerca Oncolgica IRO, Barcelona, Spain
    Am J Hematol 72:234-42. 2003
    ..These data suggest that, although leukocytic cells display several molecules that bind plasminogen, alpha-enolase is responsible for the majority of the promotion of plasminogen activation on the surfaces of leukocytic cells...
  2. ncbi Alpha-enolase plasminogen receptor in myogenesis
    Roser Lopez-Alemany
    Institut de Recerca Oncologica, Centre d Oncologia Molecular, L Hospitalet de Llobregat, Barcelona, Spain
    Front Biosci 10:30-6. 2005
    ..In particular, the expression of alpha-enolase plasminogen receptor may serve to concentrate and enhance plasmin generation on the cell surface of migratory myoblasts contributing to efficient muscle repair...
  3. ncbi Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo
    Monica Suelves
    Centre d Oncologia Molecular, Institut de Recerca Oncologica, Barcelona, Spain
    Blood 99:2835-44. 2002
    ..Altogether, these studies demonstrate the requirement of plasmin during myogenesis in vitro and muscle regeneration in vivo...
  4. ncbi Plasmin generation dependent on alpha-enolase-type plasminogen receptor is required for myogenesis
    Roser Lopez-Alemany
    Institut de Recerca Oncològia, Centre d Oncologia Molecular, L Hospitalet de Llobregat, Barcelona, Spain
    Thromb Haemost 90:724-33. 2003
    ..This study constitutes the first indication of alpha-enolase-type plasminogen receptor as an important component of skeletal myogenesis, by concentrating and enhancing plasmin generation on the cell surface...
  5. pmc Requirement of plasminogen binding to its cell-surface receptor α-enolase for efficient regeneration of normal and dystrophic skeletal muscle
    Angels Diaz-Ramos
    IDIBELL Institut d Investigacions Biomèdiques de Bellvitge, Biological Clues of the Invasive and Metastatic Phenotype Research Group, L Hospitalet de Llobregat, Barcelona, Spain
    PLoS ONE 7:e50477. 2012
    ..These results demonstrate the novel requirement of α-enolase for restoring homeostasis of injured muscle tissue, by controlling the pericellular localization of plasmin activity...
  6. pmc uPA deficiency exacerbates muscular dystrophy in MDX mice
    Monica Suelves
    Program on Differentiation and Cancer, Center for Genomic Regulation, E 08003, Barcelona, Spain
    J Cell Biol 178:1039-51. 2007
    ..These findings underscore the importance of uPA in muscular dystrophy...
  7. ncbi The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1)
    Monica Suelves
    Program on Differentiation and Cancer, Center for Genomic Regulation, Barcelona, Spain
    Front Biosci 10:2978-85. 2005
    ..Delineating the mechanisms by which the different plasminogen activation system components regulate tissue repair will be of potential therapeutic value for severe muscle disorders...
  8. pmc α-Enolase, a multifunctional protein: its role on pathophysiological situations
    Angels Diaz-Ramos
    Biological Clues of the Invasive and Metastatic Phenotype Research Group, IDIBELL Institut d Investigacions Biomèdiques de Bellvitge, L Hospitalet de Llobregat, 08908 Barcelona, Spain
    J Biomed Biotechnol 2012:156795. 2012
    ..This paper is focused on the multiple roles of the α-enolase/plasminogen axis, related to several pathologies...
  9. ncbi Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with alphavbeta3 integrin for vitronectin binding
    Roser Lopez-Alemany
    Institut de Recerca Oncològica IRO, Centre d Oncologia Molecular, L Hospitalet de Llobregat, Barcelona, Spain
    Eur J Biochem 270:814-21. 2003
    ..These results constitute the first demonstration of the interaction of PAI-1 with the insulin response...