Enrique Lerma

Summary

Affiliation: Hospital de la Santa Creu i Sant Pau
Country: Spain

Publications

  1. doi request reprint Exon 20 PIK3CA mutations decreases survival in aggressive (HER-2 positive) breast carcinomas
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
    Virchows Arch 453:133-9. 2008
  2. ncbi request reprint Effectiveness of liquid-based cytology and papanicolaou tests in a low risk population
    Enrique Lerma
    Department of Pathology, Hospital Santa Creu i Sant Pau, Barcelona, Spain
    Acta Cytol 51:399-406. 2007
  3. ncbi request reprint Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas)
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    Mod Pathol 20:1200-7. 2007
  4. ncbi request reprint Prognostic significance of the Fas-receptor/Fas-ligand system in cervical squamous cell carcinoma
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
    Virchows Arch 452:65-74. 2008
  5. doi request reprint Genetic up-regulation and overexpression of PLEKHA7 differentiates invasive lobular carcinomas from invasive ductal carcinomas
    Barbara Castellana
    Department of Pathology, Institut de Recerca Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain
    Hum Pathol 43:1902-9. 2012
  6. doi request reprint Low-density lipoprotein receptor-related protein 1 is associated with proliferation and invasiveness in Her-2/neu and triple-negative breast carcinomas
    Lluis Catasus
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Institut d Investigació Biomèdica IIB Sant Pau, Autonomous University of Barcelona, 08041 Barcelona, Spain
    Hum Pathol 42:1581-8. 2011
  7. doi request reprint Triple negative breast carcinomas: similarities and differences with basal like carcinomas
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
    Appl Immunohistochem Mol Morphol 17:483-94. 2009
  8. doi request reprint Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study
    Silvia de Sanjose
    IDIBELL, Institut Català d Oncologia Catalan Institute of Oncology, L Hospitalet de Llobregat, Barcelona, Spain
    Lancet Oncol 11:1048-56. 2010
  9. ncbi request reprint Telomerase activity in "suspicious" thyroid cytology
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Cancer 105:492-7. 2005
  10. ncbi request reprint Time trends of human papillomavirus types in invasive cervical cancer, from 1940 to 2007
    Laia Alemany
    Unit of Infections and Cancer, Catalan Institute of Oncology, IDIBELL, Barcelona, Spain CIBER Epidemiología y Salud Pública CIBERESP, Spain
    Int J Cancer 135:88-95. 2014

Collaborators

Detail Information

Publications27

  1. doi request reprint Exon 20 PIK3CA mutations decreases survival in aggressive (HER-2 positive) breast carcinomas
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
    Virchows Arch 453:133-9. 2008
    ..Exon 20 PIK3CA mutations are relatively frequent in Her-2+ tumors and shorten survival, whereas neither exons 9 and 20 mutations seem related with "triple negative" breast carcinomas...
  2. ncbi request reprint Effectiveness of liquid-based cytology and papanicolaou tests in a low risk population
    Enrique Lerma
    Department of Pathology, Hospital Santa Creu i Sant Pau, Barcelona, Spain
    Acta Cytol 51:399-406. 2007
    ..Pap Test and determine whether the Hybrid Capture System II (HCII) for detection of human papillomavirus (HPV) could increase the sensitivity and effectiveness of cervical screening in a low risk population...
  3. ncbi request reprint Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas)
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    Mod Pathol 20:1200-7. 2007
    ..001) and activated caspase-3 (P=0.089). IGF-IR could be as important as EGFR for the growth of these neoplasms. Basal cell carcinoma has at least two subtypes with distinct microscopic and immunohistochemical features...
  4. ncbi request reprint Prognostic significance of the Fas-receptor/Fas-ligand system in cervical squamous cell carcinoma
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
    Virchows Arch 452:65-74. 2008
    ..03) and decrease in host inflammatory response (p = 0.01). Fas-R expression by tumor cells seems unrelated to stage or lymphoid infiltrate. Tumor production of Fas-L may represent an attempt to destroy the host's lymphocytic reaction...
  5. doi request reprint Genetic up-regulation and overexpression of PLEKHA7 differentiates invasive lobular carcinomas from invasive ductal carcinomas
    Barbara Castellana
    Department of Pathology, Institut de Recerca Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain
    Hum Pathol 43:1902-9. 2012
    ..The gene expression profile in ILCs and IDCs differs in several signaling pathways. Our findings suggest that overexpression of PLEKHA7 is common in ILCs and could be a molecular marker to differentiate ILCs from IDCs...
  6. doi request reprint Low-density lipoprotein receptor-related protein 1 is associated with proliferation and invasiveness in Her-2/neu and triple-negative breast carcinomas
    Lluis Catasus
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Institut d Investigació Biomèdica IIB Sant Pau, Autonomous University of Barcelona, 08041 Barcelona, Spain
    Hum Pathol 42:1581-8. 2011
    ..046). These findings suggest a relationship between hypercholesterolemia and aggressiveness of ductal breast carcinomas...
  7. doi request reprint Triple negative breast carcinomas: similarities and differences with basal like carcinomas
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
    Appl Immunohistochem Mol Morphol 17:483-94. 2009
    ..Recent studies suggest that basal like carcinomas are originated from mammary stem cells...
  8. doi request reprint Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study
    Silvia de Sanjose
    IDIBELL, Institut Català d Oncologia Catalan Institute of Oncology, L Hospitalet de Llobregat, Barcelona, Spain
    Lancet Oncol 11:1048-56. 2010
    ..We aimed to provide novel and comprehensive data about the worldwide genotype distribution in patients with invasive cervical cancer...
  9. ncbi request reprint Telomerase activity in "suspicious" thyroid cytology
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Cancer 105:492-7. 2005
    ..The authors studied the utility of TA detection as an ancillary tool to thyroid fine-needle aspiration (FNA) for patients with nonconclusive cytologic diagnoses...
  10. ncbi request reprint Time trends of human papillomavirus types in invasive cervical cancer, from 1940 to 2007
    Laia Alemany
    Unit of Infections and Cancer, Catalan Institute of Oncology, IDIBELL, Barcelona, Spain CIBER Epidemiología y Salud Pública CIBERESP, Spain
    Int J Cancer 135:88-95. 2014
    ..The observed stability on the HPV type distribution predicts a high and stable impact of HPV vaccination in reducing the cervical cancer burden in future vaccinated generations. ..
  11. doi request reprint Human papillomavirus genotype distribution in cervical cancer cases in Spain. Implications for prevention
    Laia Alemany
    IDIBELL, Institut Català d Oncologia Catalan Institute of Oncology, L Hospitalet de Llobregat, Barcelona, Spain
    Gynecol Oncol 124:512-7. 2012
    ..Human papillomavirus (HPV) genotype distribution in invasive cervical cancer (ICC) is critical to guide the introduction and to assess the impact of HPV prophylactic vaccines. This study aims to provide specific information for Spain...
  12. doi request reprint Repression of E-cadherin by SNAIL, ZEB1, and TWIST in invasive ductal carcinomas of the breast: a cooperative effort?
    Nuria Montserrat
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, 08025 Barcelona, Spain
    Hum Pathol 42:103-10. 2011
    ....
  13. doi request reprint Radiologic evaluation of breast disorders related to pregnancy and lactation
    Josep M Sabate
    Unit of Breast Imaging, Department of Diagnostic Radiology, Hospital de la Santa Creu i Sant Pau, Avda Sant Antoni Maria Claret 167, 08025 Barcelona, Spain
    Radiographics 27:S101-24. 2007
    ..Knowledge of the unique entities that are specifically related to pregnancy and lactation and of their radiologic-pathologic appearances can help the radiologist make the correct diagnosis...
  14. pmc ASPN and GJB2 Are Implicated in the Mechanisms of Invasion of Ductal Breast Carcinomas
    Barbara Castellana
    1 Institut de Recerca, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    J Cancer 3:175-83. 2012
    ..The association of GJB2 protein expression with invasion was confirmed by qRT-PCR in mouse tumors (P < 0.05).Conclusions: The upregulation of ASPN and GJB2 may play important roles in local invasion of breast ductal carcinomas...
  15. ncbi request reprint PTEN promoter methylation in sporadic thyroid carcinomas
    Francisco Alvarez-Nuñez
    Laboratory of Experimental Endocrinology, Institut de Recerca, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    Thyroid 16:17-23. 2006
    ..001). These results show a high frequency of PTEN promoter hypermethylation, especially in follicular tumors, suggesting its possible role in thyroid tumorigenesis...
  16. ncbi request reprint Telomerase activity in thyroid fine needle aspirates
    Josefina Mora
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Acta Cytol 48:818-24. 2004
    ..To study the utility of telomerase activity (TA) detection in thyroid fine needle aspirates (FNAs)...
  17. ncbi request reprint Cytologic diagnosis of ocular melanocytoma: a case report
    Francesca Saro
    Cytopathology Section, Department of Pathology, Hospital de la Santa Creu i Sant Pau, Spain
    Acta Cytol 52:87-90. 2008
    ..Pigmented lesions of the eye represent a challenging field from both clinical and pathologic approaches. The importance of a correct diagnosis in this case is enhanced by the delicate structures involved and their difficult accessibility...
  18. ncbi request reprint Expression profiles associated with aggressive behavior in Merkel cell carcinoma
    Maria Teresa Fernandez-Figueras
    Department of Pathology, Hospital Universitari Germans Trias i Pujol, Autonomous University of Barcelona, Barcelona, Spain
    Mod Pathol 20:90-101. 2007
    ..These findings may be helpful in predicting the clinical course of Merkel cell carcinoma and are potentially useful for the development of targeted therapies...
  19. ncbi request reprint Alterations of the p16/Rb/cyclin-D1 pathway in vulvar carcinoma, vulvar intraepithelial neoplasia, and lichen sclerosus
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
    Hum Pathol 33:1120-5. 2002
    ....
  20. ncbi request reprint Corneal transplantations from donors with cancer
    Antonio Lopez-Navidad
    Department of Organ and Tissue Procurement for Transplantation and Tissue Bank, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain
    Transplantation 83:1345-50. 2007
    ..Such acceptance is based on the fact that the cornea is an avascular tissue and metastatic dissemination is extremely unlikely...
  21. ncbi request reprint Lupus panniculitis involving the breast
    Josep M Sabate
    Unity of Breast Imaging, Department of Diagnostic Radiology, Hospital de Sant Pau, Universitat Autonoma de Barcelona, Sant Antoni M Claret 167, 08025, Barcelona, Spain
    Eur Radiol 16:53-6. 2006
    ..Differential diagnosis with carcinoma and fat necrosis and the value of core biopsy are discussed...
  22. ncbi request reprint Comparative findings of lymphocytic thyroiditis and thyroid lymphoma
    Enrique Lerma
    Department of Pathology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Acta Cytol 47:575-80. 2003
    ..To compare the cytologic features of histologically proven lymphocytic (Hashimoto's) thyroiditis (Hashimoto's thyroitidis) and primary thyroid lymphomas (TL)...
  23. ncbi request reprint Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers
    Jose Palacios
    Breast and Gynaecological Cancer Laboratory, Centro Nacional de Investigaciones Oncologicas CNIO, Madrid, Spain
    Breast Cancer Res Treat 90:5-14. 2005
    ....
  24. ncbi request reprint Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families
    Emiliano Honrado
    Department of Human Genetics, Spanish National Cancer Centre, Melchor Fernandez Almagro 3, Madrid, Spain
    Mod Pathol 20:1298-306. 2007
    ..In addition we have defined a subset of them that have somatic inactivation of the BRCA1 gene...
  25. ncbi request reprint Immunohistochemical expression of DNA repair proteins in familial breast cancer differentiate BRCA2-associated tumors
    Emiliano Honrado
    Human Genetics Department Centro Nacional Investigaciones Oncológicas Melchor Fernández Almagro, 3 28029 Madrid, Spain
    J Clin Oncol 23:7503-11. 2005
    ..Because BRCA1 and BRCA2 genes participate in the DNA repair pathway, we have performed an immunohistochemical study with markers related to this pathway to establish the profile of the three groups...
  26. ncbi request reprint [BRCA1 and BRCA2 mutations in patients with familial breast cancer]
    Pascual Bolufer
    Laboratorio de Biologia Molecular, Departamento de Biopatología Médica, Escuela de Enfermeria, Hospital Universitario La Fe, Valencia, Spain
    Med Clin (Barc) 124:10-2. 2005
    ..The present study reports the mutations found in 48 families of the Valencian Community studied in the University Hospital La Fe of Valencia (Spain)...
  27. ncbi request reprint Immunohistochemical characteristics defined by tissue microarray of hereditary breast cancer not attributable to BRCA1 or BRCA2 mutations: differences from breast carcinomas arising in BRCA1 and BRCA2 mutation carriers
    Jose Palacios
    Laboratory of Breast and Gynecological Cancer, Immunohistological Unit, Centro Nacional de Investigaciones Oncologicas, 28029 Madrid, Spain
    Clin Cancer Res 9:3606-14. 2003
    ..Therefore, it is of major importance to define the morphological, immunohistochemical, and molecular features of this group of tumors to improve genetic testing and also gain further insight into the biological characteristics of tumors...