P Iglesias

Summary

Affiliation: Hospital General
Country: Spain

Publications

  1. doi Insulin therapy in renal disease
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Diabetes Obes Metab 10:811-23. 2008
  2. ncbi Ambulatory blood pressure monitoring in patients with hyperthyroidism before and after control of thyroid function
    P Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Clin Endocrinol (Oxf) 63:66-72. 2005
  3. ncbi Serum ghrelin concentrations in patients with chronic renal failure undergoing dialysis
    Pedro Iglesias
    Department of Endocrinology, Hospital General de Segovia, Spain
    Clin Endocrinol (Oxf) 64:68-73. 2006
  4. ncbi Acute and persistent iatrogenic Cushing's syndrome after a single dose of triamcinolone acetonide
    P Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    J Endocrinol Invest 28:1019-23. 2005
  5. ncbi Resolution of macroprolactinoma-induced symptomatic hydrocephalus following cabergoline therapy
    Pedro Iglesias
    Departments of Endocrinology and Neurology, Hospital General, Segovia, Spain
    Age Ageing 33:410-2. 2004
  6. pmc Neurological picture. Intracranial calcifications and activating mutation of the calcium-sensing receptor
    P Iglesias
    Department of Endocrinology, Hospital General, Ctra de Avila s n, Segovia 40002, Spain
    J Neurol Neurosurg Psychiatry 77:1243. 2006
  7. ncbi New drugs for the treatment of hypercholesterolaemia
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Ctra de Avila s n, 40002 Segovia, Spain
    Expert Opin Investig Drugs 12:1777-89. 2003
  8. ncbi Influence of thyroid dysfunction on serum concentrations of adipocytokines
    Pedro Iglesias
    Department of Endocrinology, Hospital General, 40002 Segovia, Spain
    Cytokine 40:61-70. 2007
  9. ncbi [Therapeutic possibilities in patients with selective pituitary resistance to thyroid hormones]
    Pedro Iglesias
    Servicio de Endocrinologia, Hospital General, Segovia, Espana
    Med Clin (Barc) 130:345-50. 2008
  10. doi Alterations in thyroid function tests in aged hospitalized patients: prevalence, aetiology and clinical outcome
    P Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Clin Endocrinol (Oxf) 70:961-7. 2009

Detail Information

Publications51

  1. doi Insulin therapy in renal disease
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Diabetes Obes Metab 10:811-23. 2008
    ..In this study, we review the more relevant aspects related to insulin therapy in diabetic patients with different degrees of renal failure and in patients with ESRD, both in conservative therapy and dialysis...
  2. ncbi Ambulatory blood pressure monitoring in patients with hyperthyroidism before and after control of thyroid function
    P Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Clin Endocrinol (Oxf) 63:66-72. 2005
    ..Our aims were (1) to analyse ABPM in a group of normotensive hyperthyroid patients before and after normalizing circulating thyroid hormones and (2) to compare these results with those obtained in a group of euthyroid subjects...
  3. ncbi Serum ghrelin concentrations in patients with chronic renal failure undergoing dialysis
    Pedro Iglesias
    Department of Endocrinology, Hospital General de Segovia, Spain
    Clin Endocrinol (Oxf) 64:68-73. 2006
    ..Derangements in ghrelin secretion in patients with chronic renal failure (CRF) have not been fully evaluated...
  4. ncbi Acute and persistent iatrogenic Cushing's syndrome after a single dose of triamcinolone acetonide
    P Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    J Endocrinol Invest 28:1019-23. 2005
    ..Eight months later, cushingoid phenotype had completely disappeared and HPA function had spontaneously recovered. We review clinical features and comment on the possible pathogenic mechanisms of this particular and new form of ICS...
  5. ncbi Resolution of macroprolactinoma-induced symptomatic hydrocephalus following cabergoline therapy
    Pedro Iglesias
    Departments of Endocrinology and Neurology, Hospital General, Segovia, Spain
    Age Ageing 33:410-2. 2004
    ..Medical therapy with this dopamine agonist in this particular patient was so effective that ventriculo-peritoneal shunting could be avoided...
  6. pmc Neurological picture. Intracranial calcifications and activating mutation of the calcium-sensing receptor
    P Iglesias
    Department of Endocrinology, Hospital General, Ctra de Avila s n, Segovia 40002, Spain
    J Neurol Neurosurg Psychiatry 77:1243. 2006
  7. ncbi New drugs for the treatment of hypercholesterolaemia
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Ctra de Avila s n, 40002 Segovia, Spain
    Expert Opin Investig Drugs 12:1777-89. 2003
    ..Other lipid-lowering drugs with the ability to act at the enterocyte level, such as avasimibe and implitapide, are currently being investigated in humans...
  8. ncbi Influence of thyroid dysfunction on serum concentrations of adipocytokines
    Pedro Iglesias
    Department of Endocrinology, Hospital General, 40002 Segovia, Spain
    Cytokine 40:61-70. 2007
    ..Finally, discordant results in resistin levels in thyroid dysfunction have been reported in humans...
  9. ncbi [Therapeutic possibilities in patients with selective pituitary resistance to thyroid hormones]
    Pedro Iglesias
    Servicio de Endocrinologia, Hospital General, Segovia, Espana
    Med Clin (Barc) 130:345-50. 2008
    ..Among the drugs with the capacity for reducing TSH secretion are TR agonists, such as triiodothyroacetic acid, D-thyroxine, triiodothyropropionic acid, and L-T3...
  10. doi Alterations in thyroid function tests in aged hospitalized patients: prevalence, aetiology and clinical outcome
    P Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Clin Endocrinol (Oxf) 70:961-7. 2009
    ..Thyroid dysfunction is common in aged people and has recently been associated to mortality...
  11. doi Hypothyrodism in male patients: a descriptive, observational and cross-sectional study in a series of 260 men
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Am J Med Sci 336:315-20. 2008
    ..Adequacy of replacement treatment seems to be mainly related to the degree of thyroid hypofunction and the time from starting therapy...
  12. ncbi Peroxisome proliferator-activated receptor gamma agonists in renal disease
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Eur J Endocrinol 154:613-21. 2006
    ..Finally, tolerability and safety profile of PPARgamma agonists in patients with reduced glomerular filtration rate are also analysed...
  13. ncbi Serum thyrotropin concentration is an early marker of normalization of low triiodothyronine syndrome in aged hospitalized patients after discharge
    P Iglesias
    Department of Endocrinology, General Hospital, Segovia, Spain
    J Endocrinol Invest 33:607-11. 2010
    ..To assess short-term spontaneous evolution of alterations in thyroid function tests in aged hospitalized patients after discharge...
  14. ncbi Effects of acute infusion of erythropoietin on paradoxical responses of growth hormone to thyrotropin-releasing hormone in acromegalic patients
    J J Diez
    Department of Endocrinology, Hospital La Paz, Madrid, Spain
    Eur J Endocrinol 143:203-11. 2000
    ..v. infusion of recombinant human erythropoietin (rhEPO) on the responses of growth hormone (GH), prolactin (PRL) and thyrotropin (TSH) to thyrotropin-releasing hormone (TRH) stimulation in acromegalic patients...
  15. ncbi Effects of cholinergic muscarinic blockade on growth hormone responses to growth hormone-releasing hormone in uraemic patients
    J J Diez
    Department of Endocrinology, Hospital La Paz, Madrid, Spain
    Nephrol Dial Transplant 14:1704-9. 1999
    ....
  16. doi Hypogonadism in aged hospitalized male patients: prevalence and clinical outcome
    P Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Ctra de Colmenar, Km 9, 100, 28034, Madrid, Spain
    J Endocrinol Invest 37:135-41. 2014
    ..We also evaluated the relationships between gonadal dysfunction and in-hospital mortality...
  17. doi An analysis of the relative risk for hypothyroidism in patients with Type 2 diabetes
    J J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Diabet Med 29:1510-4. 2012
    ..We aimed to assess the relative risk for hypothyroidism in patients with Type 2 diabetes...
  18. doi Fasting hyperglycaemia and in-hospital mortality in elderly population
    P Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Int J Clin Pract 65:308-13. 2011
    ..We assessed the prevalence and prognostic significance of admission fasting hyperglycaemia in aged patients...
  19. doi Thyroid dysfunction and kidney disease
    P Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera de Colmenar, Madrid, Spain
    Eur J Endocrinol 160:503-15. 2009
    ..Finally, data from recent research suggest that TH, especially T(3), can be considered as a marker for survival in patients with kidney disease...
  20. doi [Can FT3 levels facilitate the detection of inflammation or catabolism and malnutrition in dialysis patients?]
    M J Fernandez-Reyes
    Servicio de Nefrologia, Hospital General de Segovia, Segovia
    Nefrologia 29:304-10. 2009
    ..A reduction in thyroid function in dialysis patients could be a marker of malnutrition and/or inflammation...
  21. ncbi Growth hormone responses to oral glucose and intravenous thyrotropin-releasing hormone in acromegalic patients treated by slow-release lanreotide
    J J Diez
    Department of Endocrinology, Hospital La Paz, Madrid, Spain
    J Endocrinol Invest 24:303-9. 2001
    ..The effect of SR lanreotide on GH response to glucose tolerance test was not paralleled by GH response to TRH...
  22. ncbi Current management of acromegaly
    J J Diez
    Department of Endocrinology, Hospital La Paz, Madrid, Spain
    Expert Opin Pharmacother 1:991-1006. 2000
    ..m. injections. The complications associated with somatostatin analogues are small, relative to the benefits. Lastly, compounds with a novel mechanism of action, the GH receptor antagonists, are presently under investigation...
  23. ncbi Serum insulin-like growth factor type 1, insulin-like growth factor-binding protein-1, and insulin-like growth factor-binding protein-3 concentrations in patients with thyroid dysfunction
    P Iglesias
    Department of Endocrinology, Hospital General de Segovia, Madrid, Spain
    Thyroid 11:1043-8. 2001
    ..01). The results of the present study show that thyroid status affects GH/IGF axis. Hypothyroidism is associated with significant reductions of IGF-1 and IGFBP-3, and IGFBP-1 is elevated in both hypothyroidism and hyperthyroidism...
  24. ncbi Cholinergic modulation of growth hormone responses to growth hormone-releasing hormone in uraemic patients on peritoneal dialysis
    J J Diez
    Department of Endocrinology, Hospital La Paz, Madrid, Spain
    Clin Endocrinol (Oxf) 53:587-93. 2000
    ..Blockade of muscarinic receptor with pirenzepine blunts the GH release in several clinical situations. However, little information is available on the role played by central cholinergic pathways in GH regulation in uraemic patients...
  25. doi Macroprolactinoma: a diagnostic and therapeutic update
    P Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Ctra de Colmenar, Km 9, 28034 Madrid, Spain
    QJM 106:495-504. 2013
    ..Cystic and giant prolactinomas as well as the rare cases of malignant prolactinomas have special peculiarities and entail a therapeutic challenge...
  26. ncbi The role of the novel adipocyte-derived protein adiponectin in human disease: an update
    Juan J Diez
    Servicio de Endocrinologia, Hospital Ramon y Cajal, Madrid, Spain
    Mini Rev Med Chem 10:856-69. 2010
    ..According to this hypothesis, this protein would behave as an insulin sensitizing and cardioprotective factor in the health state and as a wasting marker in the advanced states of disease...
  27. doi Severe hyperthyroidism: aetiology, clinical features and treatment outcome
    P Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, 28034 Madrid, Spain
    Clin Endocrinol (Oxf) 72:551-7. 2010
    ..001). Heart rate and size of goitre were higher in SH group than in mH and MH groups (P < 0.01). Atrial fibrillation was more frequently reported in SH group than in MH and mH groups (15.8%vs. 5.4% and 0%, respectively, P < 0.05)...
  28. doi Prevalence of thyroid dysfunction in patients with type 2 diabetes
    J J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Exp Clin Endocrinol Diabetes 119:201-7. 2011
    ..Assess the prevalence of thyroid dysfunction in patients with type 2 diabetes (T2D) in Segovia (Spain)...
  29. doi Relationship between thyrotropin and body mass index in euthyroid subjects
    J J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Exp Clin Endocrinol Diabetes 119:144-50. 2011
    ..Several studies have reported that thyrotropin (TSH) levels are slightly increased in obese subjects. On the contrary, other studies have provided no evidence for an association between thyroid status and body mass index (BMI)...
  30. ncbi Are low concentrations of serum triiodothyronine a good marker for long-term mortality in hemodialysis patients?
    M J Fernandez-Reyes
    Servicio de Nefrología H General Segovia, Segovia, Madrid
    Clin Nephrol 73:238-40. 2010
    ..Low serum free triiodothyronine (FT3) concentrations have been reported in a high percentage of chronic renal failure patients and have been considered as an independent predictor of mortality in dialysis patients...
  31. ncbi Clinical significance of anaemia associated with prolactin-secreting pituitary tumours in men
    P Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Int J Clin Pract 65:669-73. 2011
    ..Our aim has been to evaluate the prevalence of anaemia in men with prolactinomas and to assess the relationships between haemoglobin concentrations and pituitary function at diagnosis in these patients...
  32. ncbi Current treatments in the management of patients with primary hyperparathyroidism
    P Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Postgrad Med J 85:15-23. 2009
    ..A combination of drugs with diverse mechanisms of action may have a synergistic effect in the symptomatic control of PHP...
  33. doi Serum concentrations of osteocalcin, procollagen type 1 N-terminal propeptide and beta-CrossLaps in obese subjects with varying degrees of glucose tolerance
    P Iglesias
    Department of Endocrinology, Hospital Universitario Ramon y Cajal, Madrid, Spain
    Clin Endocrinol (Oxf) 75:184-8. 2011
    ..To evaluate serum levels of osteocalcin (OC), procollagen type 1 N-terminal propeptide (P1PN) and beta-CrossLaps (beta-CTx) in obese subjects and their relationship with glucose metabolism parameters...
  34. ncbi Somatostatin analogs in the treatment of medullary thyroid carcinoma
    J J Diez
    Department of Endocrinology, Hospital La Paz, Madrid, Spain
    J Endocrinol Invest 25:773-8. 2002
    ..In conclusion, therapy with different formulations of octreotide and lanreotide does not seem to modify serum concentrations of ct and carcinoembryonic antigen in patients with recurrent medullary thyroid carcinoma...
  35. ncbi Effects of short-term recombinant human growth hormone therapy on plasma leptin concentrations in dialysis patients
    Pedro Iglesias
    Department of Endocrinology, Hospital General de Segovia, C Maria Sevilla Diago, 9, 3o dcha, E 28022 Madrid, Spain
    Nephrol Dial Transplant 17:260-4. 2002
    ..We performed a prospective study to assess plasma leptin concentrations in a group of dialysis patients both before and during short-term rhGH therapy...
  36. ncbi Inflammation and malnutrition as predictors of mortality in patients on hemodialysis
    María José Fernández-Reyes
    Servicio de Nefrologia, H General, Segovia, Spain
    J Nephrol 15:136-43. 2002
    ..Although, classically, hypoalbuminemia has been attributed to malnutrition, inflammation can also predict the serum albumin concentration in dialysis patients...
  37. ncbi Serum concentrations of tumour necrosis factor-alpha (TNF-alpha) and soluble TNF-alpha receptor p55 in patients with hypothyroidism and hyperthyroidism before and after normalization of thyroid function
    Juan J Diez
    Department of Endocrinology, Hospital La Paz, Travesía Téllez 8, 4R, 28007 Madrid, Spain
    Clin Endocrinol (Oxf) 57:515-21. 2002
    ....
  38. ncbi Spontaneous subclinical hypothyroidism in patients older than 55 years: an analysis of natural course and risk factors for the development of overt thyroid failure
    Juan J Diez
    Department of Endocrinology, Hospital La Paz, 28046 Madrid, Spain
    J Clin Endocrinol Metab 89:4890-7. 2004
    ..Subjects with mildly elevated TSH have a low incidence rate of overt hypothyroidism. We recommend follow-up with clinical and biochemical monitoring in these patients...
  39. ncbi Lipoatrophic diabetes in an elderly woman: clinical course and serum adipocytokine concentrations
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Ctra Avila s n, 40002 Segovia, Spain
    Endocr J 51:279-86. 2004
    ..During this period, serum adipocytokines were periodically measured. We comment on the different etiopathogenic mechanisms and the therapeutic modalities of this rare syndrome...
  40. ncbi Growth hormone, IGF-I and its binding proteins (IGFBP-1 and -3) in adult uraemic patients undergoing peritoneal dialysis and haemodialysis
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Clin Endocrinol (Oxf) 60:741-9. 2004
    ....
  41. ncbi Growth hormone and insulin-like growth factor binding protein-1 responses to oral glucose in patients with primary hyperparathyroidism
    Juan J Diez
    Department of Endocrinology, Hospital Ramon and Cajal, Madrid, Spain
    Clin Endocrinol (Oxf) 65:27-34. 2006
    ..GH and IGFBP-1 both play a role in glucose homeostasis...
  42. ncbi Serum concentrations of adipocytokines in patients with hyperthyroidism and hypothyroidism before and after control of thyroid function
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Clin Endocrinol (Oxf) 59:621-9. 2003
    ..The aim of this study was to evaluate the circulating levels of leptin, adiponectin and resistin in patients with thyroid dysfunction before and after normalization of thyroid function with appropriate therapy...
  43. ncbi Inhaled insulin--a new therapeutic option in the treatment of diabetes mellitus
    Juan Jose Diez
    Travesía Téllez 8, 4R, 28007 Madrid, Spain
    Expert Opin Pharmacother 4:191-200. 2003
    ..Inhaled insulin currently represents the most viable alternative insulin delivery method to preprandial subcutaneous injection...
  44. ncbi Serum concentrations of leptin, adiponectin and resistin, and their relationship with cardiovascular disease in patients with end-stage renal disease
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Clin Endocrinol (Oxf) 62:242-9. 2005
    ....
  45. doi Nephrotic-range proteinuria in a patient with a giant prolactinoma
    Manuel Heras
    Department of Nephrology, Hospital General, Segovia, Spain
    Am J Kidney Dis 51:1025-8. 2008
    ..We discuss the possible pathogenic mechanisms of proteinuria that may correspond to PRL level in urine (prolactinuria) or another tumor-related protein...
  46. ncbi Pharmacological therapy of Cushing's syndrome: drugs and indications
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera de Colmenar Km 9, 28034 Madrid, Spain
    Mini Rev Med Chem 7:467-80. 2007
    ..To review the main pharmacological properties and clinical applications of the drugs used in the medical therapy of Cushing's syndrome...
  47. ncbi Eating behavior disorders in uremia: a question of balance in appetite regulation
    Abelardo Aguilera
    Servicio de Nefrologia, Hospitales Universitarios de la Princesa y la Paz, Madrid, Spain
    Semin Dial 17:44-52. 2004
    ..Uremic anorexia may be explained by a hypothalamic hyperserotoninergic state derived from a high concentration of tryptophan and low branched-chain amino acids...
  48. ncbi Effects of cinacalcet on gastrointestinal hormone release in patients with secondary hyperparathyroidism undergoing dialysis
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera de Colmenar Km 9, 28034 Madrid, Spain
    Nephrol Dial Transplant 23:1387-95. 2008
    ....
  49. ncbi Spontaneous normalization of thyrotropin concentrations in patients with subclinical hypothyroidism
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera Colmenar km 9, 28034 Madrid, Spain
    J Clin Endocrinol Metab 90:4124-7. 2005
    ..Patients with subclinical hypothyroidism may revert to normal TSH values...
  50. ncbi Thyroid status and survival in old age
    Juan J Diez
    JAMA 293:1447; author reply 1447-8. 2005
  51. ncbi [Secondary hypertension due to Cushing syndrome caused by macronodular adrenal hyperplasia, refractory to medical therapy]
    Carmen Mon
    Med Clin (Barc) 123:436-7. 2004