Carlos Guarner

Summary

Affiliation: Hospital de la Santa Creu i Sant Pau
Country: Spain

Publications

  1. ncbi request reprint Risk of a first community-acquired spontaneous bacterial peritonitis in cirrhotics with low ascitic fluid protein levels
    C Guarner
    Liver Section, Hospital de la Santa Creu i Sant Pau de Barcelona, Barcelona, Spain
    Gastroenterology 117:414-9. 1999
  2. ncbi request reprint Bacterial translocation and its consequences in patients with cirrhosis
    Carlos Guarner
    Liver Section, Gastroenterology Service, Autonomous University, Hospital de Sant Pau, Barcelona, Spain
    Eur J Gastroenterol Hepatol 17:27-31. 2005
  3. pmc Modulation of inflammatory response in a cirrhotic rat model with induced bacterial peritonitis
    Elisabet Sánchez
    Liver Section, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    PLoS ONE 8:e59692. 2013
  4. doi request reprint Development of ascites in compensated cirrhosis with severe portal hypertension treated with β-blockers
    Virginia Hernandez-Gea
    Gastrointestinal Bleeding Unit, Department of Gastroenterology, Servei de Patologia Digestiva, Hospital de la Santa Creu i Sant Pau, Universidad Autonoma de Barcelona, Barcelona, Spain
    Am J Gastroenterol 107:418-27. 2012
  5. doi request reprint Falls and cognitive dysfunction impair health-related quality of life in patients with cirrhosis
    Eva Roman
    University School of Nursing Sant Pau, Universitat Autonoma de Barcelona, Instituto de Salud Carlos III, Barcelona, Spain
    Eur J Gastroenterol Hepatol 25:77-84. 2013
  6. ncbi request reprint Acute hemodynamic response to beta-blockers and prediction of long-term outcome in primary prophylaxis of variceal bleeding
    Candid Villanueva
    Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Gastroenterology 137:119-28. 2009
  7. doi request reprint Transfusion strategies for acute upper gastrointestinal bleeding
    Candid Villanueva
    Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de Sant Pau, Autonomous University, Barcelona, Spain
    N Engl J Med 368:11-21. 2013
  8. ncbi request reprint Development of an experimental model of induced bacterial peritonitis in cirrhotic rats with or without ascites
    Elisabet Sánchez
    Liver Unit, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Am J Gastroenterol 102:1230-6. 2007
  9. ncbi request reprint Drugs plus ligation to prevent rebleeding in cirrhosis: an updated systematic review
    Angela Puente
    Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Liver Int 34:823-33. 2014
  10. doi request reprint Cognitive dysfunction in cirrhosis is associated with falls: a prospective study
    German Soriano
    Department of Gastroenterology, Institut d Investigació Biomèdica Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    Hepatology 55:1922-30. 2012

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Risk of a first community-acquired spontaneous bacterial peritonitis in cirrhotics with low ascitic fluid protein levels
    C Guarner
    Liver Section, Hospital de la Santa Creu i Sant Pau de Barcelona, Barcelona, Spain
    Gastroenterology 117:414-9. 1999
    ..The aim of this study was to identify the group of cirrhotic patients with low ascitic fluid protein levels at high risk of developing a first episode of spontaneous bacterial peritonitis during outpatient follow-up...
  2. ncbi request reprint Bacterial translocation and its consequences in patients with cirrhosis
    Carlos Guarner
    Liver Section, Gastroenterology Service, Autonomous University, Hospital de Sant Pau, Barcelona, Spain
    Eur J Gastroenterol Hepatol 17:27-31. 2005
    ..Clinical consequences of these effects of bacterial products are presently under investigation...
  3. pmc Modulation of inflammatory response in a cirrhotic rat model with induced bacterial peritonitis
    Elisabet Sánchez
    Liver Section, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    PLoS ONE 8:e59692. 2013
    ..Additional studies including more animals are required to assess if the association of antibiotic therapy and TNF-α blockade might be a possible approach to reduce mortality in cirrhotic patients with bacterial peritonitis...
  4. doi request reprint Development of ascites in compensated cirrhosis with severe portal hypertension treated with β-blockers
    Virginia Hernandez-Gea
    Gastrointestinal Bleeding Unit, Department of Gastroenterology, Servei de Patologia Digestiva, Hospital de la Santa Creu i Sant Pau, Universidad Autonoma de Barcelona, Barcelona, Spain
    Am J Gastroenterol 107:418-27. 2012
    ..Our aim was to assess the relationship between changes in HVPG induced by β-blockers and development of ascites in compensated cirrhosis with severe PHT...
  5. doi request reprint Falls and cognitive dysfunction impair health-related quality of life in patients with cirrhosis
    Eva Roman
    University School of Nursing Sant Pau, Universitat Autonoma de Barcelona, Instituto de Salud Carlos III, Barcelona, Spain
    Eur J Gastroenterol Hepatol 25:77-84. 2013
    ..Falls are frequent in patients with cirrhosis and cognitive dysfunction and can deteriorate health-related quality of life (HRQoL)...
  6. ncbi request reprint Acute hemodynamic response to beta-blockers and prediction of long-term outcome in primary prophylaxis of variceal bleeding
    Candid Villanueva
    Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Gastroenterology 137:119-28. 2009
    ..We investigated the long-term prognostic value of an acute response to beta-blockers and whether the target reduction in HVPG can be improved in primary prophylaxis...
  7. doi request reprint Transfusion strategies for acute upper gastrointestinal bleeding
    Candid Villanueva
    Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de Sant Pau, Autonomous University, Barcelona, Spain
    N Engl J Med 368:11-21. 2013
    ..The hemoglobin threshold for transfusion of red cells in patients with acute gastrointestinal bleeding is controversial. We compared the efficacy and safety of a restrictive transfusion strategy with those of a liberal transfusion strategy...
  8. ncbi request reprint Development of an experimental model of induced bacterial peritonitis in cirrhotic rats with or without ascites
    Elisabet Sánchez
    Liver Unit, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Am J Gastroenterol 102:1230-6. 2007
    ..Spontaneous bacterial peritonitis (SBP) is a severe complication of cirrhotic patients associated with a high mortality...
  9. ncbi request reprint Drugs plus ligation to prevent rebleeding in cirrhosis: an updated systematic review
    Angela Puente
    Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Autonomous University, Barcelona, Spain
    Liver Int 34:823-33. 2014
    ..We performed a systematic review to assess the value of combined therapy with EVL and β-blockers ± ISMN as compared with each treatment alone to prevent rebleeding...
  10. doi request reprint Cognitive dysfunction in cirrhosis is associated with falls: a prospective study
    German Soriano
    Department of Gastroenterology, Institut d Investigació Biomèdica Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    Hepatology 55:1922-30. 2012
    ..2; 95% confidence interval, 3.4-30.4; P < 0.001). The 1-year probability of falling was 52.3% in patients with CD and 6.5% in those without (P < 0.001)...
  11. ncbi request reprint Pharmacologic treatment of portal hypertension in the prevention of community-acquired spontaneous bacterial peritonitis
    Begoña González-Suárez
    Gastroenterology Department, Hospital Sant Pau, Barcelona, Spain
    Eur J Gastroenterol Hepatol 18:49-55. 2006
    ....
  12. ncbi request reprint The detection of bacterial DNA in blood of rats with CCl4-induced cirrhosis with ascites represents episodes of bacterial translocation
    Carlos Guarner
    Liver Section, Escuela de Patologia Digestiva, Hospital de la Sta Creu i St Pau, Barcelona, and Liver Unit, Hospital General Universitario, Alicante, Spain
    Hepatology 44:633-9. 2006
    ..In conclusion, the presence of bactDNA in biological fluids in rats with cirrhosis constitutes a marker of BT, and it is associated with a marked inflammatory response, independent of the result of the culture...
  13. doi request reprint Role of albumin treatment in patients with spontaneous bacterial peritonitis
    Maria Poca
    Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Institut d Investigacions Biomèdiques Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain
    Clin Gastroenterol Hepatol 10:309-15. 2012
    ..However, it is unclear whether it should be given to all patients with SBP; we evaluated its efficacy...
  14. doi request reprint Current endoscopic therapy of variceal bleeding
    Candid Villanueva
    Servei de Patologia Digestiva, Hospital de la Santa Creu i Sant Pau, Avgda Sant Antoni M Claret, 167, 08025 Barcelona, Spain
    Best Pract Res Clin Gastroenterol 22:261-78. 2008
    ..As compared to beta-blockers, endoscopic ligation reduces the risk of first bleeding without affecting mortality, and should be used in patients with contraindications or intolerance to beta-blockers...
  15. ncbi request reprint Maintenance of hemodynamic response to treatment for portal hypertension and influence on complications of cirrhosis
    Candid Villanueva
    Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Avgda Sant Antoni M Claret, 167, 08025 Barcelona, Spain
    J Hepatol 40:757-65. 2004
    ..The aim of this study was to assess the long-term maintenance of hemodynamic response and its influence on complications of cirrhosis...
  16. doi request reprint Risk factors for hepatic encephalopathy in patients with cirrhosis and refractory ascites: relevance of serum sodium concentration
    Monica Guevara
    Liver Unit Hospital Clínic, Universitat de Barcelona, Barcelona, Spain
    Liver Int 30:1137-42. 2010
    ..In conclusion, in patients with refractory ascites, the occurrence of HE is related to the impairment of liver and renal function and presence of hyponatraemia...
  17. ncbi request reprint Mechanisms of early decrease in systemic vascular resistance after total paracentesis: influence of flow rate of ascites extraction
    Susanna Coll
    Liver Section, Hospital del Mar, Institut Municipal d Investigacio Medica, Universitat Autonoma Barcelona, Spain
    Eur J Gastroenterol Hepatol 16:347-53. 2004
    ..An early decrease in systemic vascular resistance (SVR) after total paracentesis has been observed in ascitic patients who developed paracentesis-induced circulatory dysfunction...
  18. pmc Paracetamol in therapeutic dosages and acute liver injury: causality assessment in a prospective case series
    Mònica Sabaté
    Fundacio Institut Catala de Farmacologia, Universitat Autonoma de Barcelona, Hospital Universitari Vall d Hebron, Barcelona, Spain
    BMC Gastroenterol 11:80. 2011
    ..The aim is to describe the characteristics of patients admitted to hospital with jaundice who had previous exposure to therapeutic doses of paracetamol. An assessment of the causality role of paracetamol was performed in each case...
  19. ncbi request reprint Intestinal mucosal oxidative damage and bacterial translocation in cirrhotic rats
    Maite Chiva
    Liver Section, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Sant Antoni M Claret 167, 08025 Barcelona, Spain
    Eur J Gastroenterol Hepatol 15:145-50. 2003
    ..Alterations in the functional integrity of the intestinal barrier caused by an increased production of free radical metabolites as a consequence of portal hypertension could also facilitate bacterial translocation in cirrhotic rats...
  20. ncbi request reprint Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage
    Javier Fernandez
    IMDM and IDIBAPS, Liver Unit, Hospital Clinic, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain
    Gastroenterology 131:1049-56; quiz 1285. 2006
    ..This randomized controlled trial was aimed to compare oral norfloxacin vs intravenous ceftriaxone in the prophylaxis of bacterial infection in cirrhotic patients with gastrointestinal bleeding...
  21. ncbi request reprint Nitric oxide in ascitic fluid is an independent predictor of the development of renal impairment in patients with cirrhosis and spontaneous bacterial peritonitis
    Jose Such
    Liver Unit and Department of Immunology, Hospital General Universitario, Alicante, Spain
    Eur J Gastroenterol Hepatol 16:571-7. 2004
    ..Our aim was to assess whether patients with ascitic fluid infection show increased levels of nitric oxide, and whether this is related to the development of renal impairment...
  22. ncbi request reprint Randomized trial comparing albumin and saline in the prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients with ascites
    Javier Sola-Vera
    Liver Unit, Internal Medicine Department, Hospital General Universitario de Alicante, Spain
    Hepatology 37:1147-53. 2003
    ..01] without significant variations after albumin). In conclusion, albumin is more effective than saline in the prevention of PICD. Saline is a valid alternative to albumin when less than 6 L of ascitic fluid is evacuated...
  23. ncbi request reprint Effect of Lactobacillus johnsonii La1 and antioxidants on intestinal flora and bacterial translocation in rats with experimental cirrhosis
    Maite Chiva
    Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret, 167 Barcelona 08025, Spain
    J Hepatol 37:456-62. 2002
    ..The aim of the present study was to determine the effect of Lactobacillus johnsonii La1 and antioxidants on intestinal flora, endotoxemia, and bacterial translocation in cirrhotic rats...
  24. ncbi request reprint Bacterial translocation is downregulated by anti-TNF-alpha monoclonal antibody administration in rats with cirrhosis and ascites
    Rubén Francés
    CIBER HEPAD, Instituto de Salud Carlos III, Madrid, Spain
    J Hepatol 46:797-803. 2007
    ..The aim of the current study was to evaluate the effect of anti-TNF-alpha mAb treatment on the incidence of bacterial translocation and systemic infections in rats with cirrhosis and ascites...