Antonio Garcia de Herreros
Affiliation: Hospital del Mar
FrÃas A, Lambies G, ViÃ±as Castells R, MartÃnez Guillamon C, Dave N, GarcÃa de Herreros A, et al
. A Switch in Akt Isoforms Is Required for Notch-Induced Snail1 Expression and Protection from Cell Death. Mol Cell Biol. 2015;36:923-40 pubmed publisher
..Moreover, Notch protects ECs from oxidative stress-induced apoptosis through an Akt2- and Snail1-dependent mechanism. ..
DÃaz V, de Herreros A. F-box proteins: Keeping the epithelial-to-mesenchymal transition (EMT) in check. Semin Cancer Biol. 2016;36:71-9 pubmed publisher
Vinyoles M, Del Valle Pérez B, Curto J, Viñas Castells R, Alba Castellón L, Garcia de Herreros A, et al
. Multivesicular GSK3 sequestration upon Wnt signaling is controlled by p120-catenin/cadherin interaction with LRP5/6. Mol Cell. 2014;53:444-57 pubmed publisher
..These results, besides elucidating how GSK3 is sequestered into MVBs, support this mechanism as cause of ?-catenin stabilization by Wnt. ..
Beltran M, Aparicio Prat E, Mazzolini R, Millanes Romero A, MassÃ³ P, Jenner R, et al
. Splicing of a non-coding antisense transcript controls LEF1 gene expression. Nucleic Acids Res. 2015;43:5785-97 pubmed publisher
..Thus, these results indicate that LEF1 gene expression is attenuated by an antisense non-coding RNA and that this NAT function is regulated by the balance between its spliced and unspliced forms. ..
Alba Castellón L, Olivera Salguero R, Mestre Farrera A, Peña R, Herrera M, Bonilla F, et al
. Snail1-Dependent Activation of Cancer-Associated Fibroblast Controls Epithelial Tumor Cell Invasion and Metastasis. Cancer Res. 2016;76:6205-6217 pubmed
..Cancer Res; 76(21); 6205-17. ©2016 AACR. ..
De Herreros A, Peiro S, Nassour M, Savagner P. Snail family regulation and epithelial mesenchymal transitions in breast cancer progression. J Mammary Gland Biol Neoplasia. 2010;15:135-47 pubmed publisher
..We also analyze the contribution of EMT and Snail genes in the process of tumorigenesis using the mammary gland as cellular model. ..