Pablo Garcia-Pavia

Summary

Affiliation: Hospital Universitario
Country: Spain

Publications

  1. Dominguez F, Cuenca S, Bilinska Z, Toro R, Villard E, Barriales Villa R, et al. Dilated Cardiomyopathy Due to BLC2-Associated Athanogene 3 (BAG3) Mutations. J Am Coll Cardiol. 2018;72:2471-2481 pubmed publisher
    ..Male sex, decreased left ventricular ejection fraction, and enlarged left ventricular end-diastolic diameter are associated with adverse outcomes in patients with BAG3 mutations. ..
  2. López Sainz Á, Salazar Mendiguchía J, Garcia Alvarez A, Campuzano Larrea O, López Garrido M, Garcia Guereta L, et al. Clinical Findings and Prognosis of Danon Disease. An Analysis of the Spanish Multicenter Danon Registry. Rev Esp Cardiol (Engl Ed). 2018;: pubmed publisher
    ..The clinical characteristics of DD differ substantially from traditional descriptions: age at presentation of DD is older, the disease is not multisystemic in women, and pre-excitation is infrequent. ..
  3. Zegri Reiriz I, de Alarcon A, Munoz P, Martinez Selles M, González Ramallo V, Miro J, et al. Infective Endocarditis in Patients With Bicuspid Aortic Valve or Mitral Valve Prolapse. J Am Coll Cardiol. 2018;71:2731-2740 pubmed publisher
    ..Our findings suggest that BAV and MVP should be classified as high-risk IE conditions and the case for IEAP should be reconsidered. ..
  4. Ware J, Amor Salamanca A, Tayal U, Govind R, Serrano I, Salazar Mendiguchía J, et al. Genetic Etiology for Alcohol-Induced Cardiac Toxicity. J Am Coll Cardiol. 2018;71:2293-2302 pubmed publisher
    ..Familial evaluation and genetic testing should be considered in patients presenting with ACM. ..
  5. request reprint
    Garcia Pavia P, Goicolea Ruigomez J, López Mínguez J, Fresneda Roldán P, Nogales Asensio J, Domínguez J, et al. [Endovascular treatment of long-term complications following surgical repair of aortic coarctation]. Rev Esp Cardiol. 2010;63:473-7 pubmed
    ..We describe our experience with this complex procedure and discuss a number of associated technical considerations, including vascular access, occlusion of the supraaortic arteries, and the use of intravascular ultrasound. ..
  6. Amor Salamanca A, Guzzo Merello G, Gonzalez Lopez E, Dominguez F, Restrepo Córdoba A, Cobo Marcos M, et al. Prognostic Impact and Predictors of Ejection Fraction Recovery in Patients With Alcoholic Cardiomyopathy. Rev Esp Cardiol (Engl Ed). 2018;71:612-619 pubmed publisher
    ..Beta-blocker treatment, QRS <120ms and absence of diuretics are independent predictors of LVEF recovery. LVEF recovery is similar in moderate drinkers and abstainers. ..
  7. Guzzo Merello G, Segovia J, Dominguez F, Cobo Marcos M, Gómez Bueno M, Avellana P, et al. Natural history and prognostic factors in alcoholic cardiomyopathy. JACC Heart Fail. 2015;3:78-86 pubmed publisher
    ..Atrial fibrillation, QRS width >120 ms, and the absence of beta-blocker therapy identify patients with a poor outcome. Alcohol abstainers and those who reduce intake to a moderate degree show similar clinical outcomes. ..
  8. Garcia Pavia P, Tome Esteban M, Rapezzi C. [Amyloidosis. Also a heart disease]. Rev Esp Cardiol. 2011;64:797-808 pubmed publisher
    ..We review in detail when and how to establish the diagnosis and how to treat these patients' cardiac involvement and the underlying amyloid disease. ..
  9. Cuenca S, Ruiz Cano M, Gimeno Blanes J, Jurado A, Salas C, Gomez Diaz I, et al. Genetic basis of familial dilated cardiomyopathy patients undergoing heart transplantation. J Heart Lung Transplant. 2016;35:625-35 pubmed publisher
    ..Detailed familial studies remain critical to determine the pathogenicity of underlying genetic defects in a substantial number of cases. ..

More Information

Publications18

  1. Alejandra Restrepo Cordoba M, Campuzano O, Ripoll Vera T, Cobo Marcos M, Mademont Soler I, Gámez J, et al. Usefulness of Genetic Testing in Hypertrophic Cardiomyopathy: an Analysis Using Real-World Data. J Cardiovasc Transl Res. 2017;10:35-46 pubmed publisher
    ..Genetic findings are not useful to predict prognosis in most HCM patients. By contrast, real-world data reinforce the usefulness of genetic testing to provide genetic counselling and to enable cascade genetic screening. ..
  2. Guzzo Merello G, Dominguez F, González López E, Cobo Marcos M, Gómez Bueno M, Fernandez Lozano I, et al. Malignant ventricular arrhythmias in alcoholic cardiomyopathy. Int J Cardiol. 2015;199:99-105 pubmed publisher
    ..Malignant ventricular arrhythmias are more frequent in ACM than in IDCM. LBBB identifies ACM patients with increased risk of SCD. No malignant ventricular arrhythmias were found during follow-up in ACM patients when LVEF was ≥40%. ..
  3. González López E, Gallego Delgado M, Guzzo Merello G, de Haro Del Moral F, Cobo Marcos M, Robles C, et al. Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction. Eur Heart J. 2015;36:2585-94 pubmed publisher
    ..ATTRwt is an underdiagnosed disease that accounts for a significant number (13%) of HFpEF cases. The effect of emerging TTR-modifying drugs should be evaluated in these patients. ..
  4. Gonzalez Lopez E, López Sainz Á, Garcia Pavia P. Diagnosis and Treatment of Transthyretin Cardiac Amyloidosis. Progress and Hope. Rev Esp Cardiol (Engl Ed). 2017;70:991-1004 pubmed publisher
    ..This review describes the broad clinical spectrum of ATTR in detail, as well as recent advances in the diagnosis and treatment of this condition. ..
  5. Amor Salamanca A, Castillo S, Gonzalez Vioque E, Dominguez F, Quintana L, Lluís Ganella C, et al. Genetically Confirmed Familial Hypercholesterolemia in Patients With Acute Coronary Syndrome. J Am Coll Cardiol. 2017;70:1732-1740 pubmed publisher
    ..FH clinical algorithms do not accurately classify patients with FH. Genetic testing should be advocated in young patients with ACS and high LDL-C levels to allow prompt identification of patients with FH and relatives at risk. ..
  6. Garcia Pavia P, Tomas J, Alonso Pulpon L. Late-onset angioedema due to an angiotensin-converting enzyme inhibitor. Can J Cardiol. 2007;23:315-6 pubmed
    ..Angioedema due to angiotensin-converting enzyme inhibitors usually appears during the first weeks of treatment. Late-onset angioedema is often unrecognized...
  7. Ramos Martínez A, Roque F, Fariñas M, Muñoz P, Verde E, Cuerpo G, et al. Prognostic factors of infective endocarditis in patients on hemodialysis: A case series from a National Multicenter Registry. Int J Cardiol. 2017;241:295-301 pubmed publisher
    ..5%) died during hospitalization. HD patients with IE present a high mortality. Advanced age and complications, such as heart failure, CNS stroke or septic shock, are associated with mortality. ..
  8. Padron Barthe L, Dominguez F, Garcia Pavia P, Lara Pezzi E. Animal models of arrhythmogenic right ventricular cardiomyopathy: what have we learned and where do we go? Insight for therapeutics. Basic Res Cardiol. 2017;112:50 pubmed publisher
    ..We also describe gaps in our knowledge of the disease, with the goal of stimulating research and improving patient outcomes. ..
  9. Garcia Pavia P, Syrris P, Salas C, Evans A, Mirelis J, Cobo Marcos M, et al. Desmosomal protein gene mutations in patients with idiopathic dilated cardiomyopathy undergoing cardiac transplantation: a clinicopathological study. Heart. 2011;97:1744-52 pubmed publisher