Laura I Furlong

Summary

Affiliation: Hospital del Mar
Country: Spain

Publications

  1. pmc Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases
    Anna Bauer-Mehren
    Research Programme on Biomedical Informatics GRIB, IMIM Hospital del Mar Research Institute, Universitat Pompeu Fabra, Barcelona, Spain
    PLoS ONE 6:e20284. 2011
  2. pmc Automatic filtering and substantiation of drug safety signals
    Anna Bauer-Mehren
    Research Programme on Biomedical Informatics GRIB, IMIM Hospital del Mar Research Institute, DCEX, Universitat Pompeu Fabra, Barcelona, Spain
    PLoS Comput Biol 8:e1002457. 2012
  3. doi request reprint Human diseases through the lens of network biology
    Laura I Furlong
    Research Programme on Biomedical Informatics GRIB, Hospital del Mar Medical Research Institute IMIM, Universitat Pompeu Fabra UPF, c Dr Aiguader, 88, 08003 Barcelona, Spain
    Trends Genet 29:150-9. 2013
  4. pmc Challenges in the association of human single nucleotide polymorphism mentions with unique database identifiers
    Philippe E Thomas
    Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Department of Bioinformatics, Schloss Birlinghoven, 53754 Sankt Augustin, Germany
    BMC Bioinformatics 12:S4. 2011
  5. pmc OSIRISv1.2: a named entity recognition system for sequence variants of genes in biomedical literature
    Laura I Furlong
    Research Unit on Biomedical Informatics GRIB, IMIM, UPF, PRBB, C Dr, Aiguader 88, E 08003 Barcelona, Spain
    BMC Bioinformatics 9:84. 2008
  6. pmc From SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathways
    Anna Bauer-Mehren
    IMIM Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Spain
    BMC Bioinformatics 10:S6. 2009
  7. doi request reprint DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks
    Anna Bauer-Mehren
    Research Programme on Biomedical Informatics GRIB IMIM, DCEXS, Universitat Pompeu Fabra, C Dr Aiguader 88, 08003 Barcelona, Spain
    Bioinformatics 26:2924-6. 2010
  8. pmc Pathway databases and tools for their exploitation: benefits, current limitations and challenges
    Anna Bauer-Mehren
    Research Unit on Biomedical Informatics GRIB, IMIM Hospital del Mar, Universitat Pompeu Fabra, Barcelona Biomedical Research Park, Dr Aiguader 88, Barcelona, Spain
    Mol Syst Biol 5:290. 2009
  9. ncbi request reprint Identifying gene-specific variations in biomedical text
    Roman Klinger
    Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing, Schloss Birlinghoven, 53754 Sankt Augustin, Germany
    J Bioinform Comput Biol 5:1277-96. 2007

Detail Information

Publications9

  1. pmc Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseases
    Anna Bauer-Mehren
    Research Programme on Biomedical Informatics GRIB, IMIM Hospital del Mar Research Institute, Universitat Pompeu Fabra, Barcelona, Spain
    PLoS ONE 6:e20284. 2011
    ..Moreover, with the unprecedented wealth of information available, even obtaining such catalogue is extremely difficult...
  2. pmc Automatic filtering and substantiation of drug safety signals
    Anna Bauer-Mehren
    Research Programme on Biomedical Informatics GRIB, IMIM Hospital del Mar Research Institute, DCEX, Universitat Pompeu Fabra, Barcelona, Spain
    PLoS Comput Biol 8:e1002457. 2012
    ..The methodology and workflows presented offer a novel approach to explore the molecular mechanisms underlying adverse drug reactions...
  3. doi request reprint Human diseases through the lens of network biology
    Laura I Furlong
    Research Programme on Biomedical Informatics GRIB, Hospital del Mar Medical Research Institute IMIM, Universitat Pompeu Fabra UPF, c Dr Aiguader, 88, 08003 Barcelona, Spain
    Trends Genet 29:150-9. 2013
    ....
  4. pmc Challenges in the association of human single nucleotide polymorphism mentions with unique database identifiers
    Philippe E Thomas
    Fraunhofer Institute for Algorithms and Scientific Computing SCAI, Department of Bioinformatics, Schloss Birlinghoven, 53754 Sankt Augustin, Germany
    BMC Bioinformatics 12:S4. 2011
    ..g. the search for biological implications. To overcome these challenges, procedures to map textual mentions of variations to database identifiers need to be developed...
  5. pmc OSIRISv1.2: a named entity recognition system for sequence variants of genes in biomedical literature
    Laura I Furlong
    Research Unit on Biomedical Informatics GRIB, IMIM, UPF, PRBB, C Dr, Aiguader 88, E 08003 Barcelona, Spain
    BMC Bioinformatics 9:84. 2008
    ..Thus, automatic systems for the identification of citations of allelic variants of genes in biomedical texts are required...
  6. pmc From SNPs to pathways: integration of functional effect of sequence variations on models of cell signalling pathways
    Anna Bauer-Mehren
    IMIM Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Spain
    BMC Bioinformatics 10:S6. 2009
    ..However, no strategy has been developed to integrate this information with biological networks, with the ultimate goal of studying the impact of the functional effect of SNPs in the structure and dynamics of biological networks...
  7. doi request reprint DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene-disease networks
    Anna Bauer-Mehren
    Research Programme on Biomedical Informatics GRIB IMIM, DCEXS, Universitat Pompeu Fabra, C Dr Aiguader 88, 08003 Barcelona, Spain
    Bioinformatics 26:2924-6. 2010
    ..Moreover, DisGeNET permits multicolouring of nodes (genes/diseases) according to standard disease classification for expedient visualization...
  8. pmc Pathway databases and tools for their exploitation: benefits, current limitations and challenges
    Anna Bauer-Mehren
    Research Unit on Biomedical Informatics GRIB, IMIM Hospital del Mar, Universitat Pompeu Fabra, Barcelona Biomedical Research Park, Dr Aiguader 88, Barcelona, Spain
    Mol Syst Biol 5:290. 2009
    ..However, are the knowledge repositories of signalling pathways ready to realize the systems biology promise? In this article we aim to initiate this discussion and to provide some insights on this issue...
  9. ncbi request reprint Identifying gene-specific variations in biomedical text
    Roman Klinger
    Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing, Schloss Birlinghoven, 53754 Sankt Augustin, Germany
    J Bioinform Comput Biol 5:1277-96. 2007
    ..The performance of this novel approach is evaluated, and improved results in comparison to state-of-the-art systems are reported...