Research Topics
| C R FumazSummaryAffiliation: Hospital Universitari Germans Trias i Pujol Country: Spain Publications
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Detail Information
Publications
Assessment of changes in adherence and quality of life after the simplification of antiretroviral treatmentCarmina R Fumaz
IAPAC Mon 9:145, 165. 2003
Influence of the type of pegylated interferon on the onset of depressive and neuropsychiatric symptoms in HIV-HCV coinfected patientsC R Fumaz
Universitat Autonoma de Barcelona, Barcelona, Spain
AIDS Care 19:138-45. 2007....
Long-term neuropsychiatric disorders on efavirenz-based approaches: quality of life, psychologic issues, and adherenceCarmina R Fumaz
Lluita contra la SIDA Foundation, HIV Unit Germans Trias i Pujol Hospital, Autonomous University of Barcelona, Barcelona, Spain
J Acquir Immune Defic Syndr 38:560-5. 2005..Efavirenz has been associated with neuropsychiatric disorders, although little is known about its long-term toxicity...
Quality of life, emotional status, and adherence of HIV-1-infected patients treated with efavirenz versus protease inhibitor-containing regimensCarmina R Fumaz
HIV Unit, Fundació Lluita SIDA and IrsiCaixa Retrovirology Laboratory, Germans Trias i Pujol University Hospital, Badalona, Catalonia, Spain
J Acquir Immune Defic Syndr 29:244-53. 2002....
Benefit of switching from a protease inhibitor (PI) to nevirapine in PI-experienced patients suffering acquired HIV-related lipodystrophy syndrome (AHL): interim analysis at 3 months of follow-upE Negredo
Fundació Lluita contra la Sida, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
Antivir Ther 4:23-8. 1999..Maintenance of viral suppression was equivalent in both treatment groups. Additional data with longer follow-up are needed to confirm these results...
Prospective randomized two-Arm controlled study to determine the efficacy of a specific intervention to improve long-term adherence to highly active antiretroviral therapyA Tuldrá
HIV Unit, Fundació Lluita SIDA and IrsiCaixa Retrovirology Laboratory, Germans Trias i Pujol University Hospital, Badalona, Spain
J Acquir Immune Defic Syndr 25:221-8. 2000..Interventions to ensure a high level of adherence during a relatively long-term period of therapy are necessary...
Antiretroviral treatment simplification with nevirapine in protease inhibitor-experienced patients with hiv-associated lipodystrophy: 1-year prospective follow-up of a multicenter, randomized, controlled studyL Ruiz
IrsiCaixa Foundation, Retrovirology Laboratory and HIV Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
J Acquir Immune Defic Syndr 27:229-36. 2001..Small nonrandomized studies have suggested a beneficial role of PI-sparing regimens on lipodystrophy...
Antiretroviral therapy interruption guided by CD4 cell counts and plasma HIV-1 RNA levels in chronically HIV-1-infected patientsLidia Ruiz
Fundació IrsiCaixa and HIV Clinical Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
AIDS 21:169-78. 2007..We evaluated the safety of CD4 cell count and plasma HIV-1 RNA (pVL)-guided treatment interruptions (GTI) and determined predictors of duration of treatment interruption...
Psychological impact of structured treatment interruptions in patients with prolonged undetectable HIV-1 viral loadsA Tuldrá
Fundació Lluita SIDA HIV Clinical Unit and IrsiCaixa Retrovirology Laboratory, Catalonia, Spain
AIDS 15:1904-6. 2001..However, a close follow-up of patients during interruption periods is advisable to avoid difficulties reported at treatment resumption presenting a risk to patients' health...
Sustained antiretroviral treatment adherence in survivors of the pre-HAART era: attitudes and beliefsC R Fumaz
Lluita contra la SIDA Foundation, Barcelona, Spain
AIDS Care 20:796-805. 2008..Adherence was more related to beliefs about health and illness than to the characteristics of medication or level of knowledge about treatment. Care adherence interventions should include assessment of health beliefs...
Neuropsychiatric symptoms associated with efavirenz: prevalence, correlates, and management. A neurobehavioral reviewJose A Muñoz-Moreno
Lluita Contra la SIDA Foundation Germans Trias i Pujol University Hospital, Badalona, Barcelona, Spain
AIDS Rev 11:103-9. 2009..Different recommendations on the assessment of efavirenz-related adverse events are also provided...
Reconstructive treatment for antiretroviral-associated facial lipoatrophy: a prospective study comparing autologous fat and synthetic substancesEugenia Negredo
HIV Unit, Fundació de la Lluita contra la SIDA, Germans Trias i Pujol University Hospital, Universitat Autonoma de Barcelona, Barcelona, Spain
AIDS Patient Care STDS 20:829-37. 2006..Similar results were observed for all degrees of severity and between genders. Polyacrylamide gel provided the longest lasting benefits...
Variability in non-nucleoside reverse transcriptase and protease inhibitors concentrations among HIV-infected adults in routine clinical practiceJose Molto
Lluita contra la SIDA Foundation, Germans Trias i Pujol Hospital, Badalona, Barcelona, Spain
Br J Clin Pharmacol 63:715-21. 2007....
Interruptions of antiretroviral therapy in human immunodeficiency virus infection: are they detrimental to neurocognitive functioning?Jose A Muñoz-Moreno
Lluita contra la SIDA Foundation, Germans Trias i Pujol University Hospital, Badalona, Barcelona, Catalonia, Spain
J Neurovirol 16:208-18. 2010..Additionally, neurocognitive functioning was observed to be more impaired in the same individuals. Further studies should examine the potential negative effects of antiretroviral therapy interruptions on neurocognitive functioning...
[Recommendations from GESIDA/SEFH/PNS to improve adherence to antiviral treatment (2004)]Hernando Knobel
Servicio Medicina Interna, Hospital del Mar, Barcelona, Spain
Enferm Infecc Microbiol Clin 23:221-31. 2005..The choice of therapy, only one aspect of the multidimensional problem of adherence, must be a careful and individualized decision; however, simpler regimens with regard to the number of pills and daily dose are desirable...
Alternation of antiretroviral drug regimens for HIV infection. A randomized, controlled trialJavier Martinez-Picado
IrsiCaixa Foundation, Hospital Germans Trias i Pujol, Carretera de Canyet s n, 08916 Badalona, Spain
Ann Intern Med 139:81-9. 2003..Mathematical modeling has suggested that alternating antiretroviral regimens while patients' viral load remains suppressed would minimize HIV resistance mutations...
Virological, immunological, and clinical impact of switching from protease inhibitors to nevirapine or to efavirenz in patients with human immunodeficiency virus infection and long-lasting viral suppressionEugenia Negredo
Fundació Lluita contra la Sida, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain
Clin Infect Dis 34:504-10. 2002..Quality of life significantly improved for groups A and B. In patients receiving effective PI-based therapy, the replacement of the PI with either nevirapine or efavirenz is safe and virologically effective...
Assessing self-reported adherence to HIV therapy by questionnaire: the SERAD (Self-Reported Adherence) StudyJose A Muñoz-Moreno
Lluita contra la SIDA Foundation, Badalona, Barcelona, Catalonia, Spain
AIDS Res Hum Retroviruses 23:1166-75. 2007....
Low levels of adherence to antiretroviral therapy in HIV-1-infected women with menstrual disordersCarmina R Fumaz
Lluita contra la SIDA Foundation, Germans Trias i Pujol University Hospital, Badalona, Barcelona, Spain
AIDS Patient Care STDS 23:463-8. 2009..The subjective attribution of these irregularities to antiretrovirals seems to affect medication intake, possibly favoring negative clinical consequences...
Variability in non-nucleoside reverse transcriptase and protease inhibitor concentrations among HIV-infected adults in routine clinical practiceJose Molto
Lluita contra la SIDA Foundation, Badalona, Barcelona, Spain
Br J Clin Pharmacol 62:560-6. 2006....
Nadir CD4 cell count predicts neurocognitive impairment in HIV-infected patientsJose A Muñoz-Moreno
Lluita contra la SIDA Foundation, Germans Trias i Pujol University Hospital, Badalona, Barcelona, Catalonia, Spain
AIDS Res Hum Retroviruses 24:1301-7. 2008..We found differences in neurocognitive functioning in relation to nadir CD4 count in HIV-infected patients. Attention should be given to this value in the management of neurocognitive protection in HIV infection...
