Andres Esteban

Summary

Affiliation: Hospital Universitario de Getafe
Country: Spain

Publications

  1. doi request reprint Evolution of mortality over time in patients receiving mechanical ventilation
    Andres Esteban
    Hospital Universitario de Getafe and Centro de Investigación Biomédica en red de Enfermedades Respiratorias, Spain
    Am J Respir Crit Care Med 188:220-30. 2013
  2. ncbi request reprint Acute respiratory distress syndrome: evaluation and management
    I Cortes
    CIBER de Enfermedades Respiratorias, Intensive Care Department, Hospital Universitario de Getafe, Madrid, Spain
    Minerva Anestesiol 78:343-57. 2012
  3. pmc Prediction of death and prolonged mechanical ventilation in acute lung injury
    Ognjen Gajic
    Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Crit Care 11:R53. 2007
  4. pmc Clinical risk conditions for acute lung injury in the intensive care unit and hospital ward: a prospective observational study
    Niall D Ferguson
    Interdepartmental Division of Critical Care Medicine, University Health Network, University of Toronto, 399 Bathurst Street, F2 150, Toronto, Ontario M5T 2S8, Canada
    Crit Care 11:R96. 2007
  5. ncbi request reprint Sepsis incidence and outcome: contrasting the intensive care unit with the hospital ward
    Andres Esteban
    Intensive Care Unit, Hospital Universitario de Getafe, Madrid, Spain
    Crit Care Med 35:1284-9. 2007
  6. ncbi request reprint Evolution of mechanical ventilation in response to clinical research
    Andres Esteban
    Intensive Care Unit, Hospital Universitario de Getafe, Carretera de Toledo Km 12, 500, 28905 Getafe, Madrid, Spain
    Am J Respir Crit Care Med 177:170-7. 2008
  7. ncbi request reprint Comparison of clinical criteria for the acute respiratory distress syndrome with autopsy findings
    Andres Esteban
    Hospital Universitario de Getafe, Madrid, Spain
    Ann Intern Med 141:440-5. 2004
  8. ncbi request reprint Noninvasive positive-pressure ventilation for respiratory failure after extubation
    Andres Esteban
    Unidad de Cuidados Intensivos, Hospital Universitario de Getafe, Madrid, Spain
    N Engl J Med 350:2452-60. 2004
  9. ncbi request reprint Outcome of older patients receiving mechanical ventilation
    Andres Esteban
    Servicio de Cuidados Intensivos, Hospital Universitario de Getafe, Carretera de Toledo km 12500, 28905 Madrid, Spain
    Intensive Care Med 30:639-46. 2004
  10. ncbi request reprint Airway pressures, tidal volumes, and mortality in patients with acute respiratory distress syndrome
    Niall D Ferguson
    Hospital Universitario de Getafe, Madrid, Spain
    Crit Care Med 33:21-30. 2005

Detail Information

Publications53

  1. doi request reprint Evolution of mortality over time in patients receiving mechanical ventilation
    Andres Esteban
    Hospital Universitario de Getafe and Centro de Investigación Biomédica en red de Enfermedades Respiratorias, Spain
    Am J Respir Crit Care Med 188:220-30. 2013
    ..67-0.92). Conclusions: Patient characteristics and ventilation practices have changed over time, and outcomes of mechanically ventilated patients have improved. Clinical trials registered with www.clinicaltrials.gov (NCT01093482). ..
  2. ncbi request reprint Acute respiratory distress syndrome: evaluation and management
    I Cortes
    CIBER de Enfermedades Respiratorias, Intensive Care Department, Hospital Universitario de Getafe, Madrid, Spain
    Minerva Anestesiol 78:343-57. 2012
    ..This review emphasizes clinical aspects in the evaluation and management of ARDS in the ICUs and updates the latest advances in these therapies...
  3. pmc Prediction of death and prolonged mechanical ventilation in acute lung injury
    Ognjen Gajic
    Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    Crit Care 11:R53. 2007
    ..We aimed to identify risk factors for a combined end-point of death and/or prolonged ventilator dependence and developed an ALI-specific prediction model...
  4. pmc Clinical risk conditions for acute lung injury in the intensive care unit and hospital ward: a prospective observational study
    Niall D Ferguson
    Interdepartmental Division of Critical Care Medicine, University Health Network, University of Toronto, 399 Bathurst Street, F2 150, Toronto, Ontario M5T 2S8, Canada
    Crit Care 11:R96. 2007
    ....
  5. ncbi request reprint Sepsis incidence and outcome: contrasting the intensive care unit with the hospital ward
    Andres Esteban
    Intensive Care Unit, Hospital Universitario de Getafe, Madrid, Spain
    Crit Care Med 35:1284-9. 2007
    ..To describe the outcome of patients with sepsis according to location on a ward or in an intensive care unit...
  6. ncbi request reprint Evolution of mechanical ventilation in response to clinical research
    Andres Esteban
    Intensive Care Unit, Hospital Universitario de Getafe, Carretera de Toledo Km 12, 500, 28905 Getafe, Madrid, Spain
    Am J Respir Crit Care Med 177:170-7. 2008
    ..Recent literature in mechanical ventilation includes strong evidence from randomized trials. Little information is available regarding the influence of these trials on usual clinical practice...
  7. ncbi request reprint Comparison of clinical criteria for the acute respiratory distress syndrome with autopsy findings
    Andres Esteban
    Hospital Universitario de Getafe, Madrid, Spain
    Ann Intern Med 141:440-5. 2004
    ..The American-European Consensus Conference definition for the acute respiratory distress syndrome (ARDS) has never been validated...
  8. ncbi request reprint Noninvasive positive-pressure ventilation for respiratory failure after extubation
    Andres Esteban
    Unidad de Cuidados Intensivos, Hospital Universitario de Getafe, Madrid, Spain
    N Engl J Med 350:2452-60. 2004
    ..We conducted a multicenter, randomized trial to evaluate the effect of noninvasive positive-pressure ventilation on mortality in this clinical setting...
  9. ncbi request reprint Outcome of older patients receiving mechanical ventilation
    Andres Esteban
    Servicio de Cuidados Intensivos, Hospital Universitario de Getafe, Carretera de Toledo km 12500, 28905 Madrid, Spain
    Intensive Care Med 30:639-46. 2004
    ..To determine the threshold of age that best discriminates the survival of mechanically ventilated patients and to estimate the outcome of mechanically ventilated older patients...
  10. ncbi request reprint Airway pressures, tidal volumes, and mortality in patients with acute respiratory distress syndrome
    Niall D Ferguson
    Hospital Universitario de Getafe, Madrid, Spain
    Crit Care Med 33:21-30. 2005
    ....
  11. doi request reprint Characteristics and outcomes of ventilated patients according to time to liberation from mechanical ventilation
    Oscar Penuelas
    Intensive Care Unit, Hospital Universitario de Getafe, Carretera de Toledo Km 12, 500, Madrid, Spain
    Am J Respir Crit Care Med 184:430-7. 2011
    ..A new classification of patients based on the duration of liberation of mechanical ventilation has been proposed...
  12. doi request reprint Genetic predisposition to acute kidney injury induced by severe sepsis
    Pablo Cardinal-Fernández
    Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, CibeRes, Madrid, Spain
    J Crit Care 28:365-70. 2013
    ..The aim of this study was to demonstrate that candidate gene polymorphisms are associated with an increased risk of acute kidney injury (AKI)...
  13. ncbi request reprint Outcome of mechanically ventilated patients who require a tracheostomy
    Fernando Frutos-Vivar
    Hospital Universitario de Getafe, Madrid, Spain
    Crit Care Med 33:290-8. 2005
    ..To estimate the prevalence of, the risk factors associated with, and the outcome of tracheostomy in a heterogeneous population of mechanically ventilated patients...
  14. ncbi request reprint Incidence, risk factors, and outcome of ventilator-associated pneumonia
    Eva Tejerina
    Intensive Care Unit, Hospital Universitario de Getafe, 28905 Getafe, Madrid, Spain
    J Crit Care 21:56-65. 2006
    ..The purpose of this study is to determine the incidence, risk factors, and outcome of ventilator-associated pneumonia (VAP)...
  15. ncbi request reprint Risk factors for extubation failure in patients following a successful spontaneous breathing trial
    Fernando Frutos-Vivar
    Intensive Care Unit, Hospital Universitario de Getafe, Carretera de Toledo Km 12, 500, 28905 Getafe, Madrid, Spain
    Chest 130:1664-71. 2006
    ..To assess the factors associated with reintubation in patients who had successfully passed a spontaneous breathing trial...
  16. ncbi request reprint Prognosis factors and outcome of community-acquired pneumonia needing mechanical ventilation
    Eva Tejerina
    Intensive Care Unit, Hospital Universitario de Getafe, 28905 Getafe, Madrid, Spain
    J Crit Care 20:230-8. 2005
    ....
  17. doi request reprint Comparison of the Berlin definition for acute respiratory distress syndrome with autopsy
    Arnaud W Thille
    Departamento de Cuidados Intensivos, Hospital Universitario de Getafe, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Madrid, Spain
    Am J Respir Crit Care Med 187:761-7. 2013
    ..Using clinical criteria the revised Berlin definition for ARDS allowed the identification of severe ARDS of more than 72 hours as a homogeneous group of patients characterized by a high proportion of DAD...
  18. ncbi request reprint Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study
    Andres Esteban
    Unidad de Cuidados Intensivos, Hospital Universitario de Getafe, Carretera de Toledo Km 12, 5, 28905 Getafe, Madrid, Spain
    JAMA 287:345-55. 2002
    ..The outcome of patients receiving mechanical ventilation for particular indications has been studied, but the outcome in a large number of unselected, heterogeneous patients has not been reported...
  19. doi request reprint Vascular dysfunction in sepsis: effects of the peroxynitrite decomposition catalyst MnTMPyP
    Nicolas Nin
    Hospital Universitario de Getafe, CIBER de Enfermedades Respiratorias, Madrid, Spain
    Shock 36:156-61. 2011
    ..Peroxynitrite scavenging protects from vascular dysfunction in sepsis...
  20. doi request reprint Early and small changes in serum creatinine concentrations are associated with mortality in mechanically ventilated patients
    Nicolas Nin
    Centro de Investigación Biomédica en Red de Enfermedades Respiratorias CIBERES, Hospital Universitario de Getafe, Madrid, Spain
    Shock 34:109-16. 2010
    ..Our study suggests that SCr0 greater than 1.40 mg/dL and, in patients with low baseline SCr, a DeltaSCr greater than 0.31 are predictors of in-hospital mortality in mechanically ventilated patients...
  21. ncbi request reprint Large tidal volume mechanical ventilation induces vascular dysfunction in rats
    Nicolas Nin
    Servicio de Cuidados Intensivos, Hospital Universitario de Getafe, Madrid, Spain
    J Trauma 59:711-6. 2005
    ..Experimental studies have shown that mechanical ventilation using high tidal volumes (V(T)) damages the lungs, causing pulmonary edema. We tested the hypothesis that high V(T) ventilation in rats induces major vascular dysfunction...
  22. doi request reprint Rats surviving injurious mechanical ventilation show reversible pulmonary, vascular and inflammatory changes
    Nicolas Nin
    Servicio de Cuidados Intensivos and CIBER de Enfermedades Respiratorias CB06 06 0044, Instituto de Salud Carlos III, Hospital Universitario de Getafe, Carretera de Toledo, km 12, 500, 28905 Madrid, Spain
    Intensive Care Med 34:948-56. 2008
    ..To describe the time course of the changes in pulmonary and vascular function, and systemic inflammation induced by injurious mechanical ventilation...
  23. doi request reprint Pulmonary vascular dysfunction induced by high tidal volume mechanical ventilation
    Carmen Menendez
    Departamento de Farmacologia, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain
    Crit Care Med 41:e149-55. 2013
    ..We analyzed the changes in the pulmonary vascular function in a model of ventilator-induced acute lung injury...
  24. ncbi request reprint Ventilation-induced lung injury in rats is associated with organ injury and systemic inflammation that is attenuated by dexamethasone
    Nicolas Nin
    Servicio de Cuidados Intensivos, Hospital Universitario de Getafe, Madrid, Spain
    Crit Care Med 34:1093-8. 2006
    ..To determine whether mechanical ventilation using high tidal volume is associated with nonpulmonary organ dysfunction that can be attenuated by dexamethasone...
  25. doi request reprint Role of peroxynitrite in sepsis-induced acute kidney injury in an experimental model of sepsis in rats
    Mariana Seija
    Departmento de Cuidados Intensivos, Hospital Universitario de Getafe, Madrid, Spain
    Shock 38:403-10. 2012
    ..Nitro-oxidative stress is involved in sepsis-induced AKI, and protein nitration seems to be one mechanism involved...
  26. ncbi request reprint Interaction between hemoglobin and glutathione in the regulation of blood flow in normal and septic pigs
    Carmen Tejedor
    Servicio de Cuidados Intensivios, Hospital Universitario de Getafe, Madrid, Spain
    Crit Care Med 30:2493-500. 2002
    ..Sepsis is a pathophysiologic state characterized by vasodilation mediated, at least in part, by an excessive release of nitric oxide. The role of nitrosothiols (RSNOs) in these changes is unknown...
  27. doi request reprint Clinical diagnoses and autopsy findings: discrepancies in critically ill patients*
    Eva Tejerina
    Intensive Care Unit, Hospital Universitario de Getafe, Getafe, Spain
    Crit Care Med 40:842-6. 2012
    ..To determine the proportion of clinical errors by comparing clinical and pathological diagnoses, and to evaluate changes of errors over time...
  28. doi request reprint Outcome of reintubated patients after scheduled extubation
    Fernando Frutos-Vivar
    Hospital Universitario de Getafe and CIBER Enfermedades Respiratorias, Madrid, Spain
    J Crit Care 26:502-9. 2011
    ..The main objective of study was to evaluate the outcome of patients who require reintubation after elective extubation...
  29. doi request reprint High-tidal volume ventilation aggravates sepsis-induced multiorgan dysfunction in a dexamethasone-inhibitable manner
    Nicolas Nin
    Hospital Universitario de Getafe and Universidad Europea de Madrid, Madrid, Spain
    Shock 31:429-34. 2009
    ..Dexamethasone averts mechanical ventilation-induced changes under conditions of bacterial sepsis...
  30. doi request reprint Antioxidant effect of human adult adipose-derived stromal stem cells in alveolar epithelial cells undergoing stretch
    Oscar Penuelas
    Critical Care Department, Hospital Universitario de Getafe, Madrid, Spain
    Respir Physiol Neurobiol 188:1-8. 2013
    ..The aim of the present study was to evaluate the antioxidant role of human adult adipose tissue-derived stromal cells (hADSCs) when human alveolar epithelial cells were subjected to injurious cyclic overstretching...
  31. doi request reprint A Metabolomic Approach to the Pathogenesis of Ventilator-induced Lung Injury
    Jose L Izquierdo-García
    From the Centro de Investigación Biomédica en Red de Enfermedades Respiratorias CIBERES, Madrid, Spain J L I G, N N, Y R, L M C, M D P, P F S, C C, A E, J R C, and J A L Centro Nacional de Investigaciones Cardiovasculares CNIC, Madrid, Spain J L I G and J R C Centro de Metabolómica y Bioanálisis CEMBIO, Facultad de Farmacia, Universidad CEU San Pablo, Madrid, Spain S N, M E, A G, and C B Hospital Universitario de Torrejón, Madrid, Spain N N Department of Critical Care, Hospital Universitario de Getafe, Madrid, Spain Y R, L M C, M D P, P F S, A E, and J A L Universidad Complutense de Madrid, Madrid, Spain C C and J R C and Universidad Europea de Madrid, Madrid, Spain J A L
    Anesthesiology 120:694-702. 2014
    ..The objective of this study was to discover biomarkers of acute lung injury induced by mechanical ventilation (ventilator-induced lung injury [VILI]), by using MRS and MS...
  32. ncbi request reprint Chronology of histological lesions in acute respiratory distress syndrome with diffuse alveolar damage: a prospective cohort study of clinical autopsies
    Arnaud W Thille
    Departamento de Cuidados Intensivos, Hospital Universitario de Getafe, CIBER de Enfermedades Respiratorias, Madrid, Spain Medical Intensive Care Unit, University Hospital of Poitiers, Poitiers, France
    Lancet Respir Med 1:395-401. 2013
    ..However, the chronology of histological lesions is not well established. We aimed to determine the time to onset of exudative or proliferative changes and end-stage fibrosis in ARDS...
  33. ncbi request reprint Outcome of older critically ill patients: a matched cohort study
    Inmaculada Rodríguez-Regañón
    Department of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain
    Gerontology 52:169-73. 2006
    ..Admission of older patients to intensive care units is a controversial issue...
  34. ncbi request reprint Genetic predisposition to acute respiratory distress syndrome in patients with severe sepsis
    Pablo Cardinal-Fernández
    Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, CibeRes, Madrid, Spain
    Shock 39:255-60. 2013
    ..The objective of this study was to analyze the association between candidate gene polymorphisms and susceptibility to acute respiratory distress syndrome (ARDS) in patients with severe sepsis...
  35. doi request reprint Aging increases the susceptibility to injurious mechanical ventilation
    Nicolas Nin
    Servicio de Cuidados Intensivos and CIBER de Enfermedades Respiratorias CB06 06 0044, Instituto de Salud Carlos III, 28905 Madrid, Spain
    Intensive Care Med 34:923-31. 2008
    ..To test the hypothesis that aging increases the susceptibility to organ dysfunction and systemic inflammation induced by injurious mechanical ventilation...
  36. doi request reprint Role of free radicals in vascular dysfunction induced by high tidal volume ventilation
    Leticia Martínez-Caro
    Centro de Investigación en Red de Enfermedades Respiratorias CibeRes, Hospital Universitario de Getafe, Universidad Europea de Madrid, Carretera de Toledo, km 12 500, Getafe, 28905 Madrid, Spain
    Intensive Care Med 35:1110-9. 2009
    ..To demonstrate that increased formation of reactive oxygen (ROS) and nitrogen species (RNS) is involved in VILI-induced vascular dysfunction...
  37. doi request reprint Clinical characteristics and outcomes of patients with 2009 influenza A(H1N1) virus infection with respiratory failure requiring mechanical ventilation
    Nicolas Nin
    Hospital Universitario de Getafe and CIBER de Enfermedades Respiratorias, Madrid, Spain
    J Crit Care 26:186-92. 2011
    ..The purpose of the study was to describe the clinical characteristics and outcomes of critically ill patients with 2009 influenza A(H1N1)...
  38. pmc Transcriptional profiling and genotyping of degraded nucleic acids from autopsy tissue samples after prolonged formalin fixation times
    Antonio Ferruelo
    Critical Care Department, Hospital Universitario de Getafe, Madrid, Spain
    Int J Clin Exp Pathol 4:156-61. 2011
    ..The possibility to use autopsy tissue samples, which contain nucleic acids of very poor quality, would open new possibilities for genetic studies...
  39. ncbi request reprint Pathology of acute lung injury and acute respiratory distress syndrome: a clinical-pathological correlation
    Oscar Penuelas
    Intensive Care Unit and Burn Unit, Hospital Universitario de Getafe, Getafe, Madrid, Spain
    Clin Chest Med 27:571-8; abstract vii-viii. 2006
    ..This and other management strategies have been evaluated in patients who, fulfilling the clinical criteria of acute respiratory distress syndrome, could not have diffuse alveolar damage...
  40. pmc Noninvasive positive-pressure ventilation in acute respiratory failure
    Oscar Penuelas
    Intensive Care Service, Hospital Universitario de Getafe, Madrid, Spain
    CMAJ 177:1211-8. 2007
    ..The best results (decreased need for intubation and decreased mortality) have been reported among patients with exacerbations of chronic obstructive pulmonary disease and cardiogenic pulmonary edema...
  41. doi request reprint Levosimendan increases portal blood flow and attenuates intestinal intramucosal acidosis in experimental septic shock
    Javier García-Septien
    Hospital Universitario de Getafe, European University of Madrid, Madrid, Spain
    Shock 34:275-80. 2010
    ..Treatment with levosimendan in this animal model of sepsis attenuated pulmonary vasoconstriction and improved portal blood flow, intestinal mucosal oxygenation, pulmonary function, and vascular reactivity...
  42. doi request reprint On the minute by minute variations of urine output: a study in a porcine model
    Abraham Otero
    Universidad San Pablo CEU, Boadilla del Monte, Madrid, Spain
    J Nephrol 27:45-50. 2014
    ....
  43. ncbi request reprint When to wean from a ventilator: an evidence-based strategy
    Fernando Frutos-Vivar
    Intensive Care Unit, Hospital Universitario de Getafe, Madrid, Spain
    Cleve Clin J Med 70:389, 392-3, 397 passim. 2003
    ..More study is needed to improve the criteria to predict successful spontaneous breathing and extubation, and to clarify the role of non-invasive ventilation to avoid reintubation...
  44. doi request reprint Effect of a nursing-implemented sedation protocol on weaning outcome
    Susana Arias-Rivera
    Intensive Care Unit and Burn Unit, Hospital Universitario de Getafe, Madrid, Spain
    Crit Care Med 36:2054-60. 2008
    ..To evaluate the effect of the implementation of a nursing-driven protocol of sedation on duration of intubation...
  45. ncbi request reprint Epidemiology of acute lung injury and acute respiratory distress syndrome
    Fernando Frutos-Vivar
    Intensive Care Unit, Hospital Universitario de Getafe, Madrid, Spain
    Curr Opin Crit Care 10:1-6. 2004
    ..Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are diseases with a significant influence in the public health. A better knowledge of their epidemiology could help to improve the outcome of these diseases...
  46. doi request reprint Weaning from the ventilator and extubation in ICU
    Arnaud W Thille
    Departamento de Cuidados Intensivos, Hospital Universitario de Getafe, CIBER de Enfermedades Respiratorias, Madrid, Espana
    Curr Opin Crit Care 19:57-64. 2013
    ..Both extubation delay and especially the need for reintubation are associated with poor outcomes. We aim to review the recent literature on weaning and to clarify the role of certain interventions intending to help in this process...
  47. doi request reprint Accuracy of clinical definitions of ventilator-associated pneumonia: comparison with autopsy findings
    Eva Tejerina
    Intensive Care Unit, Hospital Universitario de Getafe, Carretera de Toledo, kilómetro 12 5, 28905 Getafe Madrid, Spain
    J Crit Care 25:62-8. 2010
    ..Sensitivity, specificity, and likelihood ratios were calculated by using pathology pattern as criterion standard...
  48. ncbi request reprint Epidemiology of acute lung injury and acute respiratory distress syndrome
    Fernando Frutos-Vivar
    Intensive Care Unit, Hospital Universitario de Getafe, Madrid, Spain
    Semin Respir Crit Care Med 27:327-36. 2006
    ..Also discussed are the myriad causes of ARDS, incidence, epidemiology, mortality, and factors that influence outcome...
  49. doi request reprint [Prone position for the treatment of acute respiratory distress syndrome: a review of current literature]
    Oscar Martinez
    Servicio de Cuidados Intensivos, CIBER de Enfermedades Respiratorias CB06 06 0044, Instituto de Salud Carlos III, Hospital Universitario de Getafe, Getafe, Madrid, Espana
    Arch Bronconeumol 45:291-6. 2009
    ..Therefore, though in clinical practice this position may improve refractory hypoxemia in patients with ARDS, there is no evidence to support its systematic use...
  50. doi request reprint Efficacy of corticosteroid therapy in patients with an acute exacerbation of chronic obstructive pulmonary disease receiving ventilatory support
    Inmaculada Alía
    Intensive Care Units, Hospital Universitario de Getafe, Centros de Investigacion Biomedica en Red Enfermedades Respiratorias, Getafe, Spain
    Arch Intern Med 171:1939-46. 2011
    ....
  51. doi request reprint Organ dysfunction as estimated by the sequential organ failure assessment score is related to outcome in critically ill burn patients
    Jose A Lorente
    Unidad de Cuidados Intensivos Grandes Quemados, Hospital Universitario de Getafe, Getafe, Madrid, Spain
    Shock 31:125-31. 2009
    ..The SOFA score is useful to assess organ dysfunction in burn patients. Burn-induced organ dysfunction (early and late), as well as the change in organ dysfunction, is independently associated with mortality...
  52. pmc Unplanned extubation in the ICU: a marker of quality assurance of mechanical ventilation
    Oscar Penuelas
    Intensive Care Unit, Hospital Universitario de Getafe, Carretera de Toledo, km 12500, Getafe, 28905 Madrid, Spain
    Crit Care 15:128. 2011
    ..Also, this complication (unplanned extubation and reintubation rates) may be used as a marker of quality of weaning care in intensive care units...
  53. doi request reprint Severe acute respiratory failure secondary to acute fibrinous and organizing pneumonia requiring mechanical ventilation: a case report and literature review
    Sonia López-Cuenca
    Intensive Care Unit, Hospital Universitario de Getafe, Madrid, Spain
    Respir Care 57:1337-41. 2012
    ..There is little information regarding the pathophysiology of this illness. Important questions remain regarding this disease, including predisposing factors and management. Patients who require mechanical ventilation have poor outcomes...