Affiliation: Hospital Vall d'Hebron
- Enhanced oxidative damage in cystic fibrosis patientsC Dominguez
Centre d Investigacions en Bioquimica i Biologia Molecular, Hospital Materno Infantil Vall d Hebron, Barcelona, Spain
Biofactors 8:149-53. 1998..Glutathione reductase and superoxide dismutase activities were significantly higher than in controls. These results show a serious imbalance of CF patients between oxidant-antioxidant status leading to oxidative stress...
- Oxidative stress at onset and in early stages of type 1 diabetes in children and adolescentsC Dominguez
Biochemistry and Molecular Biology Research Centre, Vall d Hebron Hospitals, Autonomous University of Barcelona, Spain
Diabetes Care 21:1736-42. 1998..The aim of this study was to determine whether oxidative cellular damage occurs at the clinical onset of diabetes and in later stages of the disease in young patients...
- Changes in oxidant-antioxidant status in young diabetic patients from clinical onset onwardsP Martín-Gallán
Biochemistry and Molecular Biology Research Center, Autonomous University, Barcelona, Spain
J Cell Mol Med 11:1352-66. 2007..Consequently, tight lipid and glycometabolic control may have therapeutic potential by diminishing oxidative tissue-damaging effects of hyperglycaemia...
- Plasma chitotriosidase activity in multiple sclerosisM Comabella
Centre d esclerosi multiple de Catalunya, CEM Cat, Unitat de Neuroimmunologia Clinica, Hospital Universitari Vall d Hebron HUVH, Barcelona, Spain
Clin Immunol 131:216-22. 2009..Although these findings suggest a role of Chit in MS, our data do not support an association between plasma Chit activity and MS clinical course and clinical response to IFNbeta treatment...