A de la Sierra

Summary

Affiliation: Hospital Mutua de Terrassa
Country: Spain

Publications

  1. doi request reprint Profile of ambulatory blood pressure in resistant hypertension
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, Barcelona, Spain
    Hypertens Res 36:565-9. 2013
  2. doi request reprint [Blood pressure control in hospital units in Spain]
    Alejandro de la Sierra
    Servicio de Medicina Interna, Hospital Mutua Terrassa, Universidad de Barcelona, Terrassa, Barcelona, Espana
    Med Clin (Barc) 141:47-52. 2013
  3. doi request reprint Clinical differences between resistant hypertensives and patients treated and controlled with three or less drugs
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Barcelona, Spain
    J Hypertens 30:1211-6. 2012
  4. doi request reprint Blood pressure control with angiotensin receptor blocker-based three-drug combinations: key trials
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Plaza Dr Robert, 5, 08221, Terrassa, Spain
    Adv Ther 29:401-15. 2012
  5. doi request reprint [Determination of urinary albumin excretion in arterial hypertension]
    A de la Sierra
    Unidad de Hipertension, Servicio de Medicina Interna, Hospital Mutua de Terrassa, Universidad de Barcelona, Terrasa, Barcelona, Espana
    Rev Clin Esp 212:172-8. 2012
  6. doi request reprint Abnormalities of vascular function in resistant hypertension
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Spain
    Blood Press 21:104-9. 2012
  7. doi request reprint Ambulatory blood pressure monitoring and development of cardiovascular events in high-risk patients included in the Spanish ABPM registry: the CARDIORISC Event study
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Barcelona
    J Hypertens 30:713-9. 2012
  8. doi request reprint [Characteristics of patients with hypertension and metabolic syndrome attended by different specialists]
    Alejandro de la Sierra
    Servicio de Medicina Interna, Hospital Universitario Mutua Terrassa, Terrassa, Barcelona, Espana
    Med Clin (Barc) 138:145-50. 2012
  9. ncbi request reprint New developments in the diagnosis and management of resistant hypertension
    A Oliveras
    Hypertension Unit, Department of Nephrology, Hospital del Mar, Barcelona, Spain
    Curr Med Chem 19:1210-8. 2012
  10. doi request reprint [Prevention of progression and regression of target organ damage. Future strategies]
    A de la Sierra
    Unidad de Hipertension, Servicio de Medicina Interna, Hospital Mutua Terrassa, Universidad de Barcelona, Barcelona, Spain
    Rev Clin Esp 211:8-14. 2011

Detail Information

Publications36

  1. doi request reprint Profile of ambulatory blood pressure in resistant hypertension
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, Barcelona, Spain
    Hypertens Res 36:565-9. 2013
    ..In a significant number of these patients, ABPM will also be an essential tool in follow-up, especially regarding the possible effects of all therapeutic maneuvers that are devoted to bringing blood pressure into target ranges...
  2. doi request reprint [Blood pressure control in hospital units in Spain]
    Alejandro de la Sierra
    Servicio de Medicina Interna, Hospital Mutua Terrassa, Universidad de Barcelona, Terrassa, Barcelona, Espana
    Med Clin (Barc) 141:47-52. 2013
    ..The aim was to evaluate the degree of BP control in hypertensive patients attended in referral units...
  3. doi request reprint Clinical differences between resistant hypertensives and patients treated and controlled with three or less drugs
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Barcelona, Spain
    J Hypertens 30:1211-6. 2012
    ..The aim of the study was to evaluate clinical differences, target organ damage and ambulatory blood pressure monitoring in resistant hypertensive patients and patients controlled on three or less drugs...
  4. doi request reprint Blood pressure control with angiotensin receptor blocker-based three-drug combinations: key trials
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Plaza Dr Robert, 5, 08221, Terrassa, Spain
    Adv Ther 29:401-15. 2012
    ....
  5. doi request reprint [Determination of urinary albumin excretion in arterial hypertension]
    A de la Sierra
    Unidad de Hipertension, Servicio de Medicina Interna, Hospital Mutua de Terrassa, Universidad de Barcelona, Terrasa, Barcelona, Espana
    Rev Clin Esp 212:172-8. 2012
    ..The aim of the study was to evaluate the proportion of hypertensives attended in Primary Care who had an evaluation of UAE in the last year, along with the methodology of the measurement...
  6. doi request reprint Abnormalities of vascular function in resistant hypertension
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Spain
    Blood Press 21:104-9. 2012
    ....
  7. doi request reprint Ambulatory blood pressure monitoring and development of cardiovascular events in high-risk patients included in the Spanish ABPM registry: the CARDIORISC Event study
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Barcelona
    J Hypertens 30:713-9. 2012
    ..We aimed to evaluate ABPM estimates on the appearance of cardiovascular events and mortality in a cohort of high-risk treated hypertensive patients...
  8. doi request reprint [Characteristics of patients with hypertension and metabolic syndrome attended by different specialists]
    Alejandro de la Sierra
    Servicio de Medicina Interna, Hospital Universitario Mutua Terrassa, Terrassa, Barcelona, Espana
    Med Clin (Barc) 138:145-50. 2012
    ....
  9. ncbi request reprint New developments in the diagnosis and management of resistant hypertension
    A Oliveras
    Hypertension Unit, Department of Nephrology, Hospital del Mar, Barcelona, Spain
    Curr Med Chem 19:1210-8. 2012
    ....
  10. doi request reprint [Prevention of progression and regression of target organ damage. Future strategies]
    A de la Sierra
    Unidad de Hipertension, Servicio de Medicina Interna, Hospital Mutua Terrassa, Universidad de Barcelona, Barcelona, Spain
    Rev Clin Esp 211:8-14. 2011
    ....
  11. doi request reprint Clinical features of 8295 patients with resistant hypertension classified on the basis of ambulatory blood pressure monitoring
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Plaza Dr Robert 5, 08221 Terrassa, Spain
    Hypertension 57:898-902. 2011
    ..A worse risk profile is associated with true resistant hypertension, but this association is weak, thus making it necessary to assess ambulatory blood pressure monitoring for a correct diagnosis and management...
  12. doi request reprint Endothelial dysfunction is associated with increased levels of biomarkers in essential hypertension
    A de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Terrassa, Spain
    J Hum Hypertens 24:373-9. 2010
    ..These could be potentially helpful markers of high risk in hypertensive patients...
  13. doi request reprint [Risk factors in hypertensive patients without previous cardiovascular events]
    Alejandro de la Sierra
    Servicio de Medicina Interna, Hospital Mutua Terrassa, Universidad de Barcelona, Terrassa, Barcelona, Espana
    Med Clin (Barc) 136:559-64. 2011
    ....
  14. doi request reprint What is the role of direct renin inhibitors in the treatment of the hypertensive diabetic patient?
    Alejandro de la Sierra
    Hypertension Unit, Department of Internal Medicine, Hospital Mutua Terrassa, University of Barcelona, Plaza Dr Robert, 5, 08021, Terrassa, Spain
    Adv Ther 28:716-27. 2011
    ..If positive, aliskiren will be the treatment of choice in the prevention of cardiorenal disease in diabetics...
  15. doi request reprint Renin-angiotensin system blockade and reduction of cardiovascular risk: future perspectives
    Alejandro de la Sierra
    Department of Internal Medicine, Hospital Mutua Terrassa, Plaza Dr Robert 5, 08021 Terrassa, Spain
    Expert Rev Cardiovasc Ther 9:1585-91. 2011
    ....
  16. ncbi request reprint Genetic variation of the gamma subunit of the epithelial Na+ channel and essential hypertension. Relationship with salt sensitivity
    E Poch
    Servicio de Nefrologia, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Universidad de Barcelona, Spain
    Am J Hypertens 13:648-53. 2000
    ..Although these data do not support a major causative role for this polymorphism, we cannot exclude that a functional mutation elsewhere in ENaC might be associated with essential hypertension...
  17. ncbi request reprint Endothelial dysfunction in salt-sensitive essential hypertension
    E Bragulat
    Hypertension Unit, Department of Internal Medicine, , , Barcelona, Spain
    Hypertension 37:444-8. 2001
    ..Impairment of the L-arginine-nitric oxide pathway may be responsible for this abnormal endothelial response...
  18. ncbi request reprint Assessment of salt sensitivity in essential hypertension by 24-h ambulatory blood pressure monitoring
    A de la Sierra
    Department of Internal Medicine, Hospital Clinic, University of Barcelona, Spain
    Am J Hypertens 8:970-7. 1995
    ....
  19. ncbi request reprint Effect of salt intake on endothelium-derived factors in a group of patients with essential hypertension
    E Bragulat
    Hypertension Unit, Department of Internal Medicine, , Hospital Clinic, University of Barcelona, Villarroel 170, 08036-Barcelona, Spain
    Clin Sci (Lond) 101:73-8. 2001
    ..However, these alterations are not correlated with changes in blood pressure induced by the high salt intake...
  20. ncbi request reprint Effect of long-term irbesartan treatment on endothelium-dependent vasodilation in essential hypertensive patients
    E Bragulat
    Hypertension Unit, Department of Internal Medicine, IDIBAPS, Hospital Clinic, University of Barcelona, Spain
    Br J Biomed Sci 60:191-6. 2003
    ..These actions may play an important role in the vascular protecting effects of irbesartan...
  21. ncbi request reprint Microalbuminuria in essential hypertension: clinical and biochemical profile
    A de la Sierra
    Hypertension Unit, Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Spain
    Br J Biomed Sci 57:287-91. 2000
    ..Likewise, microalbuminuria is associated with the degree of renal impairment, and with increased uric acid and triglycerides and decreased HDL-cholesterol...
  22. doi request reprint Urinary albumin excretion is associated with true resistant hypertension
    A Oliveras
    Nephrology Division, Hypertension Unit, Medicine Department, Hospital Universitari del Mar, Universitat Autonoma de Barcelona, 08003 Barcelona, Spain
    J Hum Hypertens 24:27-33. 2010
    ..In patients with suspected RH, assessment of 24 h ambulatory BP is the most accurate way to detect a population with high risk for target-organ damage...
  23. ncbi request reprint Comparison of the antihypertensive effects of the fixed dose combination enalapril 10 mg/nitrendipine 20 mg vs losartan 50 mg/hydrochlorothiazide 12.5 mg, assessed by 24-h ambulatory blood pressure monitoring, in essential hypertensive patients
    A de la Sierra
    Hypertension Unit, Department of Internal Medicine, Hospital Clinic, Barcelona, Spain
    J Hum Hypertens 18:215-22. 2004
    ..E/N achieved a significantly higher office SBP control rate, but this was accompanied by an apparently higher proportion of mild adverse events...
  24. ncbi request reprint Detection of a circulating inhibitor of the Na(+)-K(+)-Cl(-) cotransport system in plasma and urine after high salt intake
    I Parés
    Department of General Internal Medicine, Hospital Clinico, Barcelona, Spain
    Am J Hypertens 8:965-9. 1995
    ..These results provide evidence of an Na(+)-K(+)-Cl- cotransport inhibitor factor in plasma and urine from salt-loaded humans, in concordance with previous reports in salt-loaded rats...
  25. ncbi request reprint [Absence of an association between the C825T polymorphism of the G-protein beta 3 subunit and salt-sensitivity in essential arterial hypertension]
    D Gonzalez-Nunez
    Servicio de Nefrologia, IDIBAPS, Hospital Clinic, Universidad de Barcelona, Espana
    Nefrologia 21:355-61. 2001
    ....
  26. ncbi request reprint Effect of long-term antihypertensive therapy with angiotensin converting enzyme inhibitors on red cell sodium transport
    A de la Sierra
    Department of Internal Medicine, Hospital Clinic, University of Barcelona, Spain
    Am J Hypertens 8:622-5. 1995
    ....
  27. doi request reprint Mitigation of calcium channel blocker-related oedema in hypertension by antagonists of the renin-angiotensin system
    A de la Sierra
    Hypertension Unit, Department of Internal Medicine, Hospital Clinic 170 Villarroel, Barcelona 08036, Spain
    J Hum Hypertens 23:503-11. 2009
    ..ARB/CCB and ACEI/CCB combination therapy is also more effective than CCB monotherapy in controlling blood pressure. These combinations represent an important advance in the management of hypertension...
  28. ncbi request reprint Treatment of hypertension in diabetes mellitus
    A de la Sierra
    Hypertension Unit, Hospital Clinic, 170 Villarroel, 08036 Barcelona, Spain
    Curr Hypertens Rep 2:335-42. 2000
    ..The potential role of this new class in the treatment of hypertension in diabetes will depend on the results of ongoing trials...
  29. ncbi request reprint Lack of correlation between two methods for the assessment of salt sensitivity in essential hypertension
    A de la Sierra
    Hypertension Unit, Department of Internal Medicine, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, Hospital Clinic, Barcelona, Spain
    J Hum Hypertens 16:255-60. 2002
    ....
  30. ncbi request reprint Chronic hypotension in hemodialysis patients: role of functional vascular changes and vasodilator agents
    E Coll
    Nephrology Unit, Hospital Clinic, Barcelona, Spain
    Clin Nephrol 69:114-20. 2008
    ....
  31. ncbi request reprint [Relationship between cardiovascular risk profile and anti-hypertensive drug use. GEDEC (Spanish group of cardiovascular studies]
    A de la Sierra
    Unidad de Hipertension, Hospital Clinic, Barcelona
    Med Clin (Barc) 115:41-5. 2000
    ..The aim of the present study was to analyze the relationship between the cardiovascular risk profile and co-morbid conditions on antihypertensive drug class use...
  32. ncbi request reprint Increased insulin resistance in salt sensitive essential hypertension
    V Giner
    Hypertension Unit, Department of Internal Medicine, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Spain
    J Hum Hypertens 15:481-5. 2001
    ..To determine the possible relationship between insulin resistance and salt sensitivity in essential hypertension...
  33. ncbi request reprint Disturbances of transmembranous sodium transport systems induced by ethanol in human erythrocytes. An approach to the pressor effect of alcohol
    A Coca
    Department of Internal Medicine, Hospital Clinico, School of Medicine, University of Barcelona, Spain
    Am J Hypertens 2:784-7. 1989
    ..Therefore, alcohol consumption could potentiate those genetic abnormalities of Na+ transport and contribute to the pathogenesis of essential hypertension...
  34. ncbi request reprint [Endothelial dysfunction in chronic renal failure]
    A Cases
    Servicio de Nefrologia, Unidad de Hipertension Arterial, Hospital Clinic, IDIBAPS, Universidad de Barcelona, Barcelona
    Nefrologia 23:42-51. 2003
  35. doi request reprint Resistant hypertension: patient characteristics, risk factors, co-morbidities and outcomes
    A Oliveras
    Department of Nephrology, Hospital del Mar, Barcelona, Spain
    J Hum Hypertens 28:213-7. 2014
    ....
  36. ncbi request reprint Molecular basis of salt sensitivity in human hypertension. Evaluation of renin-angiotensin-aldosterone system gene polymorphisms
    E Poch
    Nephrology Department, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Spain
    Hypertension 38:1204-9. 2001
    ..The BP response to high salt intake was different among genotypes of ACE I/D and 11betaHSD G534A, suggesting that these polymorphisms may be potentially useful genetic markers of salt sensitivity...