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Genomes and Genes | Maria Isabel CovasSummaryAffiliation: Hospital del Mar Country: Spain Publications
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Publications
Postprandial effects of wine consumption on lipids and oxidative stress biomarkersM I Covas
Lipids and Cardiovascular Epidemiology Unit, Institut d Investigaciò Médica, Barcelona, Spain
Drugs Exp Clin Res 29:217-23. 2003..Daily consumption of moderate doses of red wine can improve postprandial lipid profile and oxidative status when wine is ingested outside meals...
Olive oil and the cardiovascular systemMaria Isabel Covas
Institut Municipal dInvestigació Mèdica IMIM Hospital del Mar, Parc de Recerca Biomédica de Barcelona PRBB, Carrer Dr Aiguader, 80 08003 Barcelona, Spain
Pharmacol Res 55:175-86. 2007....
The effect of polyphenols in olive oil on heart disease risk factors: a randomized trialMaria Isabel Covas
Municipal Institute for Medical Research, Barcelona, Spain
Ann Intern Med 145:333-41. 2006..Little information is available on the effect of the phenolic compounds of olive oil on plasma lipid levels. No international study with a large sample size has been done...
Bioactive effects of olive oil phenolic compounds in humans: reduction of heart disease factors and oxidative damageM I Covas
Cardiovascular Risk and Nutrition Group, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, CIBER de Fisiopatología de la Obesidad y Nutrición, Parc de Recerca Biomédica de Barcelona PRBB, Barcelona, Spain
Inflammopharmacology 16:216-8. 2008..Here, we update the state of the art, and degree of evidence, of the body of knowledge concerning the protective role on lipids and lipid oxidative damage in humans of the olive oil phenolic compounds...
Postprandial LDL phenolic content and LDL oxidation are modulated by olive oil phenolic compounds in humansMaria Isabel Covas
Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d Investigacio Medica IMIM, 08003 Barcelona, Spain
Free Radic Biol Med 40:608-16. 2006..In conclusion, olive oil phenolic content seems to modulate the LDL phenolic content and the postprandial oxidative stress promoted by 40 mL olive oil ingestion in humans...
Wine and oxidative stress: up-to-date evidence of the effects of moderate wine consumption on oxidative damage in humansMaria Isabel Covas
Cardiovascular Risk and Nutrition Research Group URLEC CARIN, Institut Municipal d Investigacio Medica, CIBER de Fisiopatología de la Obesidad y Nutrición, Barcelona Biomedical Research Park, Carrer Doctor Aiguader, 88, 08003 Barcelona, Spain
Atherosclerosis 208:297-304. 2010..In this way, the postprandial oxidative stress after a meal, despite the diversity of biomarkers used for its evaluation, is counteracted by the ingestion of wine. Further studies are warranted...
Olive oil and cardiovascular healthMaria Isabel Covas
Cardiovascular Risk and Nutrition Research Group, Institut Municipal d Investigacio Medica IMIM, CIBER de Fisiopatologia de la Obesidad y Nutricion CIBEROBN, Barcelona, Spain
J Cardiovasc Pharmacol 54:477-82. 2009....
Scientific aspects that justify the benefits of the Mediterranean diet: mild-to-moderate versus heavy drinkingM I Covas
Lipids and Cardiovascular Research Unit, Municipal Institute for Medical Research IMIM, 08003 Barcelona, Spain
Ann N Y Acad Sci 957:162-73. 2002..Efficacy versus effectiveness, the role of basic and animal research, and bioavailability studies providing evidence is also discussed...
Relationship between physical activity and oxidative stress biomarkers in womenMaria Isabel Covas
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal de Investigació Mèdica, IMIM, Barcelona, Spain
Med Sci Sports Exerc 34:814-9. 2002..To examine the relationship between physical activity and levels of plasma lipid peroxides, superoxide dismutase in erythrocytes (SOD), and glutathione peroxidase (GSH-Px) in whole blood activities...
Virgin olive oil phenolic compounds: binding to human low density lipoprotein (LDL) and effect on LDL oxidationM I Covas
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d Investigacio Medica IMIM, Carrer Doctor Aiguader, 80, 08003 Barcelona, Spain
Int J Clin Pharmacol Res 20:49-54. 2000..These results provide further evidence that phenolic compounds bound to LDL are likely to protect LDL from oxidation...
Why should population attributable fractions be periodically recalculated? An example from cardiovascular risk estimation in southern EuropeMaria Grau
Epidemiology and Cardiovascular Genetics, Program of Research on Inflammatory and Cardiovascular Disorders, Institut Municipal d Investigacio Medica, 08003 Barcelona, Spain
Prev Med 51:78-84. 2010..To determine the effect of age and study period on coronary heart disease (CHD) risk attributable to cardiovascular risk factors...
Time course of changes in the expression of insulin sensitivity-related genes after an acute load of virgin olive oilValentini Konstantinidou
Cardiovascular Risk and Nutrition Research Group, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, CIBER de Fisiopatologia de la Obesidad y Nutricion CIBEROBN, Barcelona, Spain
OMICS 13:431-8. 2009....
Effect of a traditional Mediterranean diet on lipoprotein oxidation: a randomized controlled trialMontserrat Fito
Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d Investigacio Medica, IMIM Hospital del Mar, Barcelona, Spain
Arch Intern Med 167:1195-203. 2007..Despite the richness in antioxidants of the Mediterranean diet, to our knowledge, no randomized controlled trials have assessed its effect on in vivo lipoprotein oxidation...
Antioxidant paraoxonase 1 activity in the metabolic syndromeMariano Senti
Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d Investigacio Medica, E 08003 Barcelona, Spain
J Clin Endocrinol Metab 88:5422-6. 2003....
In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: a randomized controlled trialValentini Konstantinidou
Cardiovascular Risk and Nutrition Research Group, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, Centro de Investigación Biomédica Eu Red CIBER de Fisiopatología de la Obesidad y Nutrición, Barcelona, Spain
FASEB J 24:2546-57. 2010..In addition, the benefits associated with a TMD and olive oil polyphenol consumption on cardiovascular risk can be mediated through nutrigenomic effects...
trans Fatty acid consumption, lifestyle and type 2 diabetes prevalence in a Spanish populationKyriaki Papantoniou
Environmental Epidemiology Research Centre, Biomedical Research Park, 08003 Barcelona, Spain
Eur J Nutr 49:357-64. 2010..To analyse the association of trans fatty acid (TFA) consumption with the risk of type 2 diabetes and lifestyle in a South European population...
Bioavailability and antioxidant effects of olive oil phenolic compounds in humans: a reviewMontserrat Fito
Lipids and Cardiovascular Epidemiology Research Unit, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
Ann Ist Super Sanita 43:375-81. 2007..Here, we summarize the state of the art of the body of knowledge, and to which extent we have evidence, of the bioavailability and of the antioxidant benefits of olive oil phenolic compounds in humans...
Hypertensive status and lipoprotein oxidation in an elderly population at high cardiovascular riskMonica Guxens
Cardiovascular Risk and Nutrition Research Unit, Institut Municipal d Investigacio Medica, Barcelona, Spain
Am J Hypertens 22:68-73. 2009..Our aim was to assess the relationship between the degree of in vivo low-density lipoprotein (oxLDL) oxidation and the hypertensive status in a elderly population at high cardiovascular risk...
Adherence to the Mediterranean diet is associated with better mental and physical healthMiguel Angel Munoz
Cardiovascular Risk and Nutrition Research Group CARIN ULEC, IMIM Hospital del Mar Barcelona, Biomedical Research Park Parc de Recerca Biomèdica de Barcelona PRBB, c Doctor Aiguader 88, 08003 Barcelona, Spain
Br J Nutr 101:1821-7. 2009..Adherence to the Mediterranean diet was associated with higher scoring for self-perceived health...
The Mediterranean diet pattern and its main components are associated with lower plasma concentrations of tumor necrosis factor receptor 60 in patients at high risk for cardiovascular diseaseMireia Urpi-Sarda
Department of Internal Medicine, University of Barcelona, Barcelona, Spain
J Nutr 142:1019-25. 2012..01). This study suggests that a MD reduces TNFR concentrations in patients at high cardiovascular risk...
Protection of LDL from oxidation by olive oil polyphenols is associated with a downregulation of CD40-ligand expression and its downstream products in vivo in humansOlga Castañer
Cardiovascular Risk and Nutrition, Research Groups of Institut Mar d Investigacions Mèdiques Research Institute Hospital del Mar, Barcelona, Spain
Am J Clin Nutr 95:1238-44. 2012..Polyphenols could exert health benefits not only by scavenging free radicals but also by modulating gene expression...
Prevalence in the eligibility for weight loss treatment in a Mediterranean populationHelmut Schroder
Lipids and Cardiovascular Epidemiology Research Unit, Institut Municipal d Investigacio Medica, Parc de Recerca Biomedica de Barcelona, Spain
Br J Nutr 99:442-6. 2008..This trend is more pronounced in older age groups and among the population with a basic educational level...
A short screener is valid for assessing Mediterranean diet adherence among older Spanish men and womenHelmut Schroder
Cardiovascular Risk and Nutrition Research Group, IMIM Institut de Recerca del Hospital del Mar, Barcelona 08003, Spain
J Nutr 141:1140-5. 2011..The 10-y estimated coronary artery disease risk decreased as the PREDIMED score increased (P < 0.001). The MEDAS is a valid instrument for rapid estimation of adherence to the Mediterranean diet and may be useful in clinical practice...
Postprandial and short-term effects of dietary virgin olive oil on oxidant/antioxidant statusMontserrat Fito
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
Lipids 37:245-51. 2002..Virgin olive oil consumption could provide short-term benefits for LDL resistance to oxidation and in glutathione-related enzyme activities...
South-to-North gradient in lipid peroxidation in men with stable coronary artery disease in EuropeMaria Grau
Lipids and Cardiovascular Epidemiology Unit, Municipal Institute Medical Research IMIM Barcelona, Carrer Dr Aiguader, 88, E 08003 Barcelona, Spain
Eur Heart J 28:2841-9. 2007..The aim of our study was to determine whether differences exist in the degree of LDL oxidation in stable CAD patients from different regions of Europe...
Glycemic load, glycemic index, and body mass index in Spanish adultsMichelle A Mendez
Center for Research in Environmental Epidemiology, Municipal Institute of Medical Research, Biomedical Research Park, Barcelona, Spain
Am J Clin Nutr 89:316-22. 2009..Studies on obesity and glycemic index (GI) or glycemic load (GL) have had inconsistent results, perhaps in part because of underreporting or to heterogeneous dietary patterns across food cultures...
Low energy density diets are associated with favorable nutrient intake profile and adequacy in free-living elderly men and womenHelmut Schroder
Cardiovascular Risk and Nutrition Research Group CARIN ULEC, IMIM Hospital del Mar, Biomedical Research Park Parc de Recerca Biomèdica de Barcelona PRBB, 08003 Barcelona, Spain
J Nutr 138:1476-81. 2008..A low energy density diet has a higher capacity to prevent nutrient deficiency, despite lower energy content, than a high energy density diet in the elderly population studied...
Alcohol consumption is directly associated with circulating oxidized low-density lipoproteinHelmut Schroder
Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d Investigacio Medica, IMIM, Barcelona, Spain
Free Radic Biol Med 40:1474-81. 2006..No significant relationship of ox-LDL with alcohol-independent consumption of wine, beer, and spirits was observed. Alcohol consumption was independently and directly associated with circulating ox-LDL in the present population...
Validity of two short screeners for diet quality in time-limited settingsHelmut Schroder
Cardiovascular Risk and Nutrition Research Group CARIN ULEC, Program of Research in Inflammatory and Cardiovascular Disorders RICAD, IMIM Hospital del Mar, Biomedical Research Park, c Doctor Aiguader 88, 08003 Barcelona, Spain
Public Health Nutr 15:618-26. 2012..The present study assessed concurrent and construct validity of the short Diet Quality Screener (sDQS) and brief Mediterranean Diet Screener (bMDSC) questionnaires...
Mononuclear cell transcriptome response after sustained virgin olive oil consumption in humans: an exploratory nutrigenomics studyOlha Khymenets
Institut Municipal d Investigacio Medica, Hospital del Mar, Barcelona, Spain
OMICS 13:7-19. 2009..Our data support the hypothesis that 3 weeks of nutritional intervention with VOO supplementation, at doses common in the Mediterranean diet, can alter the expression of genes related to atherosclerosis development and progression...
Relationship of classical and non-classical risk factors with genetic variants relevant to coronary heart diseaseJosep Maria Manresa
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d Investigacio Medica, Barcelona, Spain
Eur J Cardiovasc Prev Rehabil 13:738-44. 2006..We aimed to determine the relationship of classical and non-classical cardiovascular risk factors with candidate gene polymorphisms potentially involved in cardiovascular risk in the general Mediterranean population...
Secular trends of obesity and cardiovascular risk factors in a Mediterranean populationHelmut Schroder
Lipids and Cardiovascular Epidemiology Research Unit, Institut Municipal d Investigacio Medica, c Doctor Aiguader 80, 08003 Barcelona, Spain
Obesity (Silver Spring) 15:557-62. 2007..To evaluate time trends of obesity, abdominal obesity, and cardiovascular risk factors (CRFs) according to BMI and waist circumference (WC) categories in a Mediterranean population...
Association of fast food consumption with energy intake, diet quality, body mass index and the risk of obesity in a representative Mediterranean populationHelmut Schroder
Lipids and Cardiovascular Epidemiology Research Unit, Institut Municipal d Investigacio Medica, IMIM Hospital de Mar, Biomedical Research Park Parc de Recerca Biomèdica de Barcelona PRBB, c Doctor Aiguader 88, 08003 Barcelona, Spain
Br J Nutr 98:1274-80. 2007..046). Fast food consumption was associated with higher energy intakes, poor diet quality and higher BMI. The likelihood of not meeting the DRI for energy, and of being obese, increased with the frequency of fast food consumption...
Antioxidant activities of hydroxytyrosol main metabolites do not contribute to beneficial health effects after olive oil ingestionOlha Khymenets
Human Pharmacology and Clinical Neurosciences Research Group, IMIM Hospital del Mar Research Institute, C Dr Aiguader 88, Barcelona, Spain
Drug Metab Dispos 38:1417-21. 2010..01-10 muM) after dietary olive oil consumption. None of the glucuronides displayed significant antioxidant activities at the concentrations tested...
Paraoxonase1-192 polymorphism modulates the effects of regular and acute exercise on paraoxonase1 activityMarta Tomas
Lipids and Cardiovascular Epidemiology Unit, Departament de Ciencies Experimentals i de la Salut, Institut Municipal d Investigacio Medica IMIM, Dr Aiguader 80, E 08003 Barcelona, Spain
J Lipid Res 43:713-20. 2002..These results suggest that the effects of regular and acute exercise on PON1 activity levels are modulated by PON1-192 polymorphism. Changes were less evident for the PON1-55 polymorphism...
[Association between paraoxonase-1 and paraoxonase-2 polymorphisms and the risk of acute myocardial infarction]Monica Guxens
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d Investigacio Medica, Barcelona, Espana
Rev Esp Cardiol 61:269-75. 2008..However, previous findings have been contradictory. The aim of this study was to investigate the association between the PON1-192 and PON2-311 polymorphisms and their interaction on AMI risk...
Antioxidant effect of virgin olive oil in patients with stable coronary heart disease: a randomized, crossover, controlled, clinical trialM Fito
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d Investigacio Medica IMIM, Carrer Doctor Aiguader, Barcelona, Spain
Atherosclerosis 181:149-58. 2005..Consumption of VOO, rich in PC, could provide beneficial effects in CHD patients as an additional and complementary intervention to the pharmacological treatment...
Concurrent and construct validity of Mediterranean diet scores as assessed by an FFQAlejandra A Benítez-Arciniega
Cardiovascular Risk and Nutrition Research Group CARIN ULEC, IMIM Hospital del Mar Barcelona, Biomedical Research Park Parc de Recerca Biomèdica de Barcelona PRBB, c Doctor Aiguader 88, 08003 Barcelona, Spain
Public Health Nutr 14:2015-21. 2011....
Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trialRamon Estruch
Institut d Investigacions Biomèdiques August Pi Sunyer, Municipal Institut for Medical Research, University of Barcelona, and Catalan Institute of Health, Barcelona, Spain
Ann Intern Med 145:1-11. 2006..The Mediterranean diet has been shown to have beneficial effects on cardiovascular risk factors...
Is dopamine behind the health benefits of red wine?Rafael de la Torre
Pharmacology Unit IMIM, Institut Municipal d Investigacio Medica, Doctor Aiguader 80, 08003 Barcelona, Spain
Eur J Nutr 45:307-10. 2006..Hydroxytyrosol is a dopamine metabolite, and also a very active naturally occurring phenol compound in olive oil...
Olive oil and oxidative stressMontserrat Fito
Lipids and Cardiovascular Epidemiology Unit and Pharmacology Research Unit, Institut Municipal d Investigacio Medica, Barcelona, Spain
Mol Nutr Food Res 51:1215-24. 2007..In this review, we summarize the state of the art, and degree of evidence, of the body of knowledge concerning the protective role of the major and minor components of olive oil on oxidative stress...
Bioavailability of phenolic compounds from olive oil and oxidative/antioxidant status at postprandial state in healthy humansT Weinbrenner
Lipids and Cardiovascular Epidemiology Unit, Institute of Medical Investigation, Barcelona, Spain
Drugs Exp Clin Res 30:207-12. 2004..The phenolic content of the olive oils administered may account for the protection of the endogenous antioxidant defenses at postprandial state after ingestion of moderate and high phenolic content olive oils...
Role of sex and time of blood sampling in SOD1 and SOD2 expression variabilityOlha Khymenets
Human Pharmacology and Clinical Neurosciences Research Group, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, Barcelona, Spain
Clin Biochem 41:1348-54. 2008..This study investigates how some of human physiological parameters, in particular sex and daytime, can contribute to the normal variation in blood gene expression...
Exocrine pancreatic cancer clinical factors were related to timing of blood extraction and influenced serum concentrations of lipidsMiquel Porta
Institut Municipal d Investigació Mèdica Hospital del Mar, Barcelona, Spain
J Clin Epidemiol 61:695-704. 2008..We analyzed the influence of clinical factors and timing of blood extraction on serum concentrations of cholesterol and triglycerides in exocrine pancreatic cancer (EPC)...
Antioxidant enzyme activity and coronary heart disease: meta-analyses of observational studiesGemma Flores-Mateo
Primary Care Centres Research Institut Jordi Gol, Barcelona, Spain
Am J Epidemiol 170:135-47. 2009....
Use of a three-day estimated food record, a 72-hour recall and a food-frequency questionnaire for dietary assessment in a Mediterranean Spanish populationH Schroder
Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d Investigacio Medica, IMIM, Barcelona, Spain
Clin Nutr 20:429-37. 2001..To assess the validity and the short-term reproducibility of a semi-quantitative, self-administrated food frequency questionnaire and a structured 72-hour recall in a Mediterranean Spanish population...
Mediterranean diet and waist circumference in a representative national sample of young SpaniardsHelmut Schroder
Cardiovascular Risk and Nutrition Research Group CARIN ULEC, Municipal Institute of Medical Research IMIM Hospital del Mar, Biomedical Research Park Parc de Recerca Biomèdica de Barcelona PRBB, Spain
Int J Pediatr Obes 5:516-9. 2010..54 cm in sex-, age- and height-adjusted WC. These results suggest that following Mediterranean dietary principles may be important in reducing the risk of high waist circumference in young people...
Anti-inflammatory effect of virgin olive oil in stable coronary disease patients: a randomized, crossover, controlled trialM Fito
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
Eur J Clin Nutr 62:570-4. 2008..To assess the effect of two similar olive oils, but with differences in their phenolic compounds (powerful antioxidant compounds), on inflammatory markers in stable coronary heart disease patients...
Response of oxidative stress biomarkers to a 16-week aerobic physical activity program, and to acute physical activity, in healthy young men and womenR Elosua
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d Investigacio Medica, Dr Aiguader 80, Barcelona 08003, Spain
Atherosclerosis 167:327-34. 2003..Regular PA increases endogenous antioxidant activity and LDL resistance to oxidation, and decreases oxidized LDL concentration; 30 min of aerobic PA decreases P-GR and B-GSH-Px activity in the first 30-60 min with a posterior recovery...
Validation of the Minnesota Leisure Time Physical Activity Questionnaire In Spanish Women. Investigators of the MARATDON GroupR Elosua
Unitat de Lipids i Epidemiologia Cardiovascular, Institut Municipal d Investigacio Medica, IMIM, Barcelona, Spain
Med Sci Sports Exerc 32:1431-7. 2000..It is important to validate PA measurement instruments in different populations. The objective was to validate the Minnesota leisure time PA questionnaire among Spanish women...
Decreased endogenous antioxidant enzymatic status in essential hypertensionJ Pedro-Botet
Hospital del Mar, Barcelona, Spain
J Hum Hypertens 14:343-5. 2000..64, P < 0.0001, respectively). The low endogenous antioxidant enzyme activities observed may in turn result in decreased superoxide anion removal leading to nitric oxide inactivation. Journal of Human Hypertension (2000) 14, 343-345..
High monetary costs of dietary patterns associated with lower body mass index: a population-based studyH Schroder
Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d Investigacio Medica, IMIM, Barcelona, Spain
Int J Obes (Lond) 30:1574-9. 2006..The purpose of this study was to determine the cost differences between low and high adherence to two dietary patterns which have been inversely associated with body mass index (BMI) and obesity...
[Prevalence of hepatitis B and hepatitis C viruses in different counties of Catalonia, Spain: cross-sectional study]Ricard Sola
Societat Catalana de Digestologia, Acadèmia de Ciències Mèdiques de Catalunya i Balears, Barcelona, Spain
Med Clin (Barc) 119:90-5. 2002..There are few data available in our community regarding the prevalence of hepatitis B (HBV) and hepatitis C (HCV) virus infection in the general population...
HPLC-tandem mass spectrometric method to characterize resveratrol metabolism in humansMireia Urpi Sarda
Nutrition and Food Science Department, CeRTA, Pharmacy School, University of Barcelona, Barcelona, Spain
Clin Chem 53:292-9. 2007..We sought to develop a method for nutritional analysis of resveratrol, a phenolic compound with purported health-promoting properties, and to determine all resveratrol metabolites...
Trends in cardiovascular risk factor prevalence (1995-2000-2005) in northeastern SpainMaria Grau
Lipids and Cardiovascular Epidemiology Unit, Municipal Institute for Medical Research IMIM, Carrer Dr Aiguader 88, Barcelona, Spain
Eur J Cardiovasc Prev Rehabil 14:653-9. 2007..Our objective was to determine the trends of cardiovascular risk factor prevalence between 1995 and 2005 in the 35-74-year-old population of Gerona, Spain...
Bioavailability of tyrosol, an antioxidant phenolic compound present in wine and olive oil, in humansM I Covas
Lipids and Cardiovascular Epidemiology Unit, Municipal Institute of Medical Research, Barcelona, Spain
Drugs Exp Clin Res 29:203-6. 2003..In summary, our results suggest that tyrosol from wine or virgin olive oil could exert beneficial effects on human health in vivo if its biological properties are confirmed in in vivo studies...
[Coronary disease protective factors: antioxidant effect of olive oil]M I Covas
, , Carrer Dr. Aiguader, 80, 08003 Barcelona, Espagne
Therapie 56:607-11. 2001..PC from diet could bind human LDL in non-supplemented volunteers. PC from virgin olive oil could bind LDL and tyrosol is bioavailable in humans from ingestion of virgin olive oil in its natural form...
Characterization of human gene expression changes after olive oil ingestion: an exploratory approachV Konstantinidou
Cardiovascular Risk and Nutrition Research Group, Institut Municipal d Investigacio Medica, Barcelona, Spain
Folia Biol (Praha) 55:85-91. 2009..Our results support the hypothesis that postprandial protective changes related to olive oil consumption could be mediated through gene expression changes...
Capillary gas chromatography-mass spectrometry quantitative determination of hydroxytyrosol and tyrosol in human urine after olive oil intakeE Miro-Casas
Unitat de Farmacologia, Universitat Autonoma de Barcelona, Barcelona, 08003, Spain
Anal Biochem 294:63-72. 2001..Our results further indicate that hydroxytyrosol and tyrosol are mainly excreted in conjugated form, since only 5.9 +/- 1.4% (hydroxytyrosol) and 13.8 +/- 5.4% (tyrosol) of the total amounts excreted in urine were in free form...
Effects of dietary fibre intake on risk factors for cardiovascular disease in subjects at high riskR Estruch
Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomèdiques August Pi Sunyer, Barcelona, Spain
J Epidemiol Community Health 63:582-8. 2009..Thus, the effects of changes in dietary fibre intake on cardiovascular risk factors were assessed over 3 months in free-living high-risk subjects...
