Montserrat Andreu

Summary

Affiliation: Hospital del Mar
Country: Spain

Publications

  1. ncbi request reprint A prospective, multicenter, population-based study of BRAF mutational analysis for Lynch syndrome screening
    Xavier Bessa
    Department of Gastroenterology, Hospital del Mar, Barcelona, Catalonia, Spain
    Clin Gastroenterol Hepatol 6:206-14. 2008
  2. ncbi request reprint Applicability of the Rockall score in patients undergoing endoscopic therapy for upper gastrointestinal bleeding
    X Bessa
    Gastroenterology Department, Hospital del Mar, Universidad Autonoma de Barcelona, Passeig Maritim 25 29, Catalonia, Spain
    Dig Liver Dis 38:12-7. 2006
  3. ncbi request reprint Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors
    Rosa M Xicola
    Department of Gastroenterology, Germans Trias i Pujol Hospital, Carretera del Canyet s n, 08916 Badalona, Barcelona, Spain
    J Natl Cancer Inst 99:244-52. 2007
  4. ncbi request reprint Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway
    Xavier Llor
    Gastroenterology Department, Germans Trias i Pujol Hospital, Universitat Autonoma de Barcelona, Spain
    Clin Cancer Res 11:7304-10. 2005
  5. ncbi request reprint Clinical performance of original and revised Bethesda guidelines for the identification of MSH2/MLH1 gene carriers in patients with newly diagnosed colorectal cancer: proposal of a new and simpler set of recommendations
    Francisco Rodriguez-Moranta
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    Am J Gastroenterol 101:1104-11. 2006
  6. doi request reprint Risk of advanced proximal neoplasms according to distal colorectal findings: comparison of sigmoidoscopy-based strategies
    Antoni Castells
    Department of Gastroenterology, Hospital Clinic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas CIBEREHD, IDIBAPS, University of Barcelona, Barcelona, Spain
    J Natl Cancer Inst 105:878-86. 2013
  7. ncbi request reprint Detection of metachronous neoplasms in colorectal cancer patients: identification of risk factors
    Belén Ballesté
    Gastroenterology Department, Hospital del Mar, and University of Barcelona, Spain
    Dis Colon Rectum 50:971-80. 2007
  8. pmc Validation and extension of the PREMM1,2 model in a population-based cohort of colorectal cancer patients
    Francesc Balaguer
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Catalonia, Spain
    Gastroenterology 134:39-46. 2008
  9. ncbi request reprint Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study
    Francesc Balaguer
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBERehd, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
    Clin Gastroenterol Hepatol 5:379-87. 2007
  10. ncbi request reprint Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer
    Sergi Castellvi-Bel
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBER EHD, IDIBAPS, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Carcinogenesis 28:1687-91. 2007

Detail Information

Publications43

  1. ncbi request reprint A prospective, multicenter, population-based study of BRAF mutational analysis for Lynch syndrome screening
    Xavier Bessa
    Department of Gastroenterology, Hospital del Mar, Barcelona, Catalonia, Spain
    Clin Gastroenterol Hepatol 6:206-14. 2008
    ..The aim of this study was to evaluate the contribution of BRAF V600E mutation analysis in the identification of MSH2/MLH1 gene mutation carriers in newly diagnosed CRC patients...
  2. ncbi request reprint Applicability of the Rockall score in patients undergoing endoscopic therapy for upper gastrointestinal bleeding
    X Bessa
    Gastroenterology Department, Hospital del Mar, Universidad Autonoma de Barcelona, Passeig Maritim 25 29, Catalonia, Spain
    Dig Liver Dis 38:12-7. 2006
    ..The Rockall score is used to assess the prognosis of patients with upper gastrointestinal bleeding...
  3. ncbi request reprint Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors
    Rosa M Xicola
    Department of Gastroenterology, Germans Trias i Pujol Hospital, Carretera del Canyet s n, 08916 Badalona, Barcelona, Spain
    J Natl Cancer Inst 99:244-52. 2007
    ....
  4. ncbi request reprint Differential features of colorectal cancers fulfilling Amsterdam criteria without involvement of the mutator pathway
    Xavier Llor
    Gastroenterology Department, Germans Trias i Pujol Hospital, Universitat Autonoma de Barcelona, Spain
    Clin Cancer Res 11:7304-10. 2005
    ..The main objectives of this study were to assess the relevance of clinically defined HNPCC patients without characteristic mutator pathway alterations and to identify their specific features...
  5. ncbi request reprint Clinical performance of original and revised Bethesda guidelines for the identification of MSH2/MLH1 gene carriers in patients with newly diagnosed colorectal cancer: proposal of a new and simpler set of recommendations
    Francisco Rodriguez-Moranta
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    Am J Gastroenterol 101:1104-11. 2006
    ..For this purpose, the National Cancer Institute outlined a set of recommendations, the Bethesda guidelines, which have recently been revised...
  6. doi request reprint Risk of advanced proximal neoplasms according to distal colorectal findings: comparison of sigmoidoscopy-based strategies
    Antoni Castells
    Department of Gastroenterology, Hospital Clinic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas CIBEREHD, IDIBAPS, University of Barcelona, Barcelona, Spain
    J Natl Cancer Inst 105:878-86. 2013
    ..This study was aimed at comparing the existing strategies of postsigmoidoscopy referral to colonoscopy in terms of accuracy and resources needed...
  7. ncbi request reprint Detection of metachronous neoplasms in colorectal cancer patients: identification of risk factors
    Belén Ballesté
    Gastroenterology Department, Hospital del Mar, and University of Barcelona, Spain
    Dis Colon Rectum 50:971-80. 2007
    ..This study was designed to identify individual and familial factors associated with the development of metachronous colorectal neoplasms in patients with colorectal cancer...
  8. pmc Validation and extension of the PREMM1,2 model in a population-based cohort of colorectal cancer patients
    Francesc Balaguer
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Catalonia, Spain
    Gastroenterology 134:39-46. 2008
    ..However, the model's performance in an unselected, population-based colorectal cancer population as well as its performance in combination with tumor MMR testing are unknown...
  9. ncbi request reprint Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study
    Francesc Balaguer
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBERehd, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
    Clin Gastroenterol Hepatol 5:379-87. 2007
    ....
  10. ncbi request reprint Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer
    Sergi Castellvi-Bel
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBER EHD, IDIBAPS, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Carcinogenesis 28:1687-91. 2007
    ..23, P = 0.007) and familial cases and controls (OR = 1.55, 95% CI = 1.10-2.19, P = 0.01) in agreement with a hypothetical moderate increase of the cancer risk linked to the C148R ARLTS1 variant, both in sporadic and familial CRC cases...
  11. doi request reprint Relationship of colonoscopy-detected serrated polyps with synchronous advanced neoplasia in average-risk individuals
    Cristina Alvarez
    Department of Gastroenterology, Hospital del Mar Cancer Research Program, IMIM Hospital del Mar Medical Research Institute, Universitat Autònoma de Barcelona Pompeu Fabra University, Barcelona, Catalonia, Spain
    Gastrointest Endosc 78:333-341.e1. 2013
    ..The presence of proximal serrated polyps and large (≥10 mm) serrated polyps (LSP) has been correlated with colorectal neoplasia...
  12. ncbi request reprint Genomic rearrangements in MSH2 and MLH1 are rare mutational events in Spanish patients with hereditary nonpolyposis colorectal cancer
    Sergi Castellvi-Bel
    Gastroenterology Department, Institut de Malalties Digestives, IDIBAPS, Barcelona, Catalonia, Spain
    Cancer Lett 225:93-8. 2005
    ..These results showed that MSH2/MLH1 rearrangements in Spanish patients at risk for HNPCC seem to be a less frequent mutational event than in other populations...
  13. ncbi request reprint Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer
    Virginia Piñol
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, University of Barcelona, Barcelona, Spain
    JAMA 293:1986-94. 2005
    ..Recently, the National Cancer Institute outlined a new set of recommendations, the revised Bethesda guidelines, for the identification of individuals with HNPCC who should be tested for microsatellite instability...
  14. doi request reprint Impact of current smoking on the clinical course of microscopic colitis
    Fernando Fernández-Bañares
    Department of Gastroenterology, Hospital Universitari Mutua Terrassa, Terrassa, Spain
    Inflamm Bowel Dis 19:1470-6. 2013
    ..Whether current smoking worsens the clinical course of microscopic colitis (MC) is unknown. The aim was to evaluate the impact of smoking on the clinical course of MC...
  15. doi request reprint Genetic susceptibility variants associated with colorectal cancer prognosis
    Anna Abuli
    Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Catalonia 08036, Spain
    Carcinogenesis 34:2286-91. 2013
    ....
  16. doi request reprint Susceptibility genetic variants associated with early-onset colorectal cancer
    María Dolores Giráldez
    Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, IDIBAPS, University of Barcelona, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Carcinogenesis 33:613-9. 2012
    ..Association of CRC susceptibility variants with some patient's familiar and personal features could be relevant for screening and surveillance strategies in this high-risk group and it should be explored in further studies...
  17. doi request reprint Susceptibility genetic variants associated with colorectal cancer risk correlate with cancer phenotype
    Anna Abuli
    Department of Gastroenterology, Hospital del Mar, Institut Municipal d Investigacio Medica, Pompeu Fabra University, Barcelona, Catalonia, Spain
    Gastroenterology 139:788-96, 796.e1-6. 2010
    ..Characterization of such a correlation would improve CRC management and prevention programs. We assessed the association between these genetic variants and CRC phenotype in patients and modeled pairwise combinations to detect epistasis...
  18. doi request reprint Association of MUTYH and MSH6 germline mutations in colorectal cancer patients
    María Dolores Giráldez
    Gastroenterology Department, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Institut d Investigacions Biomediques August Pi i Sunyer, 08036 Catalonia, Barcelona, Spain
    Fam Cancer 8:525-31. 2009
    ..037). CRC patients carrying monoallelic MUTYH mutations harbor more frequently concomitant MSH6 mutations than patients without them, thus suggesting that both genes could act cooperatively and confer together an increased CRC risk...
  19. pmc Multiple sporadic colorectal cancers display a unique methylation phenotype
    Victoria Gonzalo
    Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    PLoS ONE 9:e91033. 2014
    ..In conclusion, multiple CRC are associated with a distinct methylation phenotype, with a close association between tumor multiplicity and CIMP-high. Our results may be important to unravel the underlying mechanism of tumor multiplicity. ..
  20. ncbi request reprint Synchronous colorectal neoplasms in patients with colorectal cancer: predisposing individual and familial factors
    Virginia Piñol
    Department of Gastroenterology, IMD, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    Dis Colon Rectum 47:1192-200. 2004
    ..This study was designed to identify individual and familial characteristics associated with the development of synchronous colorectal neoplasms in patients with colorectal cancer...
  21. doi request reprint Seeking genetic susceptibility variants for colorectal cancer: the EPICOLON consortium experience
    Sergi Castellvi-Bel
    Department of Gastroenterology, Hospital Clinic, CIBERehd, IDIBAPS, University of Barcelona, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Mutagenesis 27:153-9. 2012
    ..Finishing their own pangenomic study and performing whole-exome sequencing in selected CRC samples are among EPICOLON future research prospects...
  22. doi request reprint Validation microsatellite path score in a population-based cohort of patients with colorectal cancer
    Xavier Bessa
    Hospital del Mar de Barcelona Parc de Salut Mar Passeig Marítim 25 29, 08003 Barcelona, Catalonia, Spain
    J Clin Oncol 29:3374-80. 2011
    ..However, the MsPath model's performance in an unselected, population-based colorectal cancer (CRC) population is unknown...
  23. doi request reprint A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at RBX1-EP300
    Antonio Julia
    Rheumatology Research Group, Vall d Hebron Research Institute, Barcelona, Spain
    Gut 62:1440-5. 2013
    ..We performed a GWAS on a southern European population to identify new CD risk loci...
  24. pmc Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer
    Victoria Gonzalo
    Department of Gastroenterology, Hospital Clinic, Centro de Investigación Biomédica en Red en el Area temática de Enfermedades Hepáticas y Digestivas, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
    PLoS ONE 5:e8777. 2010
    ....
  25. doi request reprint Colonoscopy versus fecal immunochemical testing in colorectal-cancer screening
    Enrique Quintero
    Department of Gastroenterology, Hospital Universitario de Canarias, Tenerife, Spain
    N Engl J Med 366:697-706. 2012
    ..Colonoscopy and fecal immunochemical testing (FIT) are accepted strategies for colorectal-cancer screening in the average-risk population...
  26. pmc New genes emerging for colorectal cancer predisposition
    Clara Esteban-Jurado
    Clara Esteban Jurado, Anna Abulí, Jenifer Muñoz, Francesc Balaguer, Teresa Ocaña, Antoni Castells, Josep M Piqué, Sergi Castellví Bel, Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, 08036 Barcelona, Catalonia, Spain
    World J Gastroenterol 20:1961-71. 2014
    ..By using whole-genome sequencing, germline mutations in the POLE and POLD1 genes have been found to be responsible for a new form of CRC genetic predisposition called polymerase proofreading-associated polyposis...
  27. pmc Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins
    Anna Abuli
    Department of Gastroenterology, IDIBAPS, Hospital Clinic, CIBERehd, University of Barcelona, Barcelona, Catalonia, Spain
    BMC Cancer 11:339. 2011
    ....
  28. pmc Identification of Lynch syndrome among patients with colorectal cancer
    Leticia Moreira
    Department of Gastroenterology, Hospital Clinic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    JAMA 308:1555-65. 2012
    ..Identification of gene carriers currently relies on germline analysis in patients with MMR-deficient tumors, but criteria to select individuals in whom tumor MMR testing should be performed are unclear...
  29. ncbi request reprint [Treatment of severe chronic constipation through the antegrade continent enema procedure]
    Miguel Pera
    Unidad de Cirugía Colorrectal Servicio de Cirugía General Hospital del Mar Barcelona España
    Cir Esp 80:403-5. 2006
    ..Since then, the patient has had a bowel movement between 1 and 3 hours after each washout, has recovered continence, and no longer wears an absorbent pad...
  30. doi request reprint Epidemiological risk factors in microscopic colitis: a prospective case-control study
    Fernando Fernández-Bañares
    Department of Gastroenterology, Hospital Universitari Mutua Terrassa, Terrassa, Spain
    Inflamm Bowel Dis 19:411-7. 2013
    ..The cause of collagenous colitis (CC) and lymphocytic colitis (LC) is unknown and epidemiological risk factors for CC and LC are not well studied. The aim was to evaluate in a case-control study epidemiological risk factors for CC and LC...
  31. ncbi request reprint Frequency of hereditary non-polyposis colorectal cancer and other colorectal cancer familial forms in Spain: a multicentre, prospective, nationwide study
    Virginia Piñol
    Department of Gastroenterology, IMD, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    Eur J Gastroenterol Hepatol 16:39-45. 2004
    ..Hereditary nonpolyposis colorectal cancer is the most common type of hereditary colorectal cancer, but its incidence remains controversial, ranging from 1 to 5%...
  32. pmc The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals
    Anna Abuli
    Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain Department of Gastroenterology, Hospital del Mar IMIM Hospital del Mar Medical Research Centre, Pompeu Fabra University, Barcelona, Catalonia, Spain
    PLoS ONE 9:e95022. 2014
    ....
  33. pmc Effectiveness of infliximab after adalimumab failure in Crohn's disease
    Maria Chaparro
    Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, 28006 Madrid, Spain
    World J Gastroenterol 18:5219-24. 2012
    ..To evaluate the effectiveness of infliximab as a second-line therapy in Crohn's disease patients after adalimumab failure...
  34. doi request reprint [Characteristics of patients with familial adenomatous polyposis in Spain. First results of the Spanish Registry of Familial Adenomatous Polyposis]
    Ignacio Alfaro
    Servicio de Gastroenterologia, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas CIBEREHD, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Barcelona, Spain
    Med Clin (Barc) 135:103-8. 2010
    ..We aimed to evaluate the clinicopathological characteristics of patients with familial adenomatous polyposis in Spain...
  35. ncbi request reprint A prospective trial comparing wireless capsule endoscopy and barium contrast series for small-bowel surveillance in hereditary GI polyposis syndromes
    Alfredo Mata
    Digestive Endoscopy Unit, Gastroenterology Department, Institut de Malaties Digestives, Barcelona, Catalonia, Spain
    Gastrointest Endosc 61:721-5. 2005
    ..The objective was to establish the effectiveness of wireless capsule endoscopy for detecting small-bowel polyps in patients with hereditary GI polyposis syndromes in comparison with barium contrast series...
  36. doi request reprint Accuracy of magnetic resonance enterography in assessing response to therapy and mucosal healing in patients with Crohn's disease
    Ingrid Ordás
    Department of Gastroenterology, Hospital Clinic of Barcelona, IDIBAPS, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Barcelona, Spain
    Gastroenterology 146:374-82.e1. 2014
    ..We assessed the accuracy of magnetic resonance enterography (MRE) in monitoring response to therapy in patients with Crohn's disease (CD) using ileocolonoscopy as a reference standard...
  37. doi request reprint Prevalence and factors related to hepatitis B and C in inflammatory bowel disease patients in Spain: a nationwide, multicenter study
    Carme Loras
    Department of Gastroenterology, Hospital Mutua de Terrassa, Fundació per la Recerca Mútua de Terrassa, Plaça Dr Robert no 5, Catalonia, Spain
    Am J Gastroenterol 104:57-63. 2009
    ..The objectives of this study are to assess the prevalence of HBV and HCV infection in IBD, in a nationwide study, and to evaluate associated risk factors...
  38. ncbi request reprint Endosonographic and manometric evaluation of internal anal sphincter in patients with chronic anal fissure and its correlation with clinical outcome after topical glyceryl trinitrate therapy
    Marta Pascual
    Colorectal Surgery Unit, Department of Surgery, Hospital del Mar, Passeig Maritim, 25 29, 08003, Barcelona, Spain
    Int J Colorectal Dis 22:963-7. 2007
    ..The second aim was to investigate the association between these findings and the outcome with topical Glyceryl trinitrate (GTN) therapy...
  39. ncbi request reprint Adaptation to Spanish language and validation of the fecal incontinence quality of life scale
    Miguel Minguez
    Department of Gastroenterology, Hospital Clinico Universitario, Valencia, Spain
    Dis Colon Rectum 49:490-9. 2006
    ..The aim of this study was to perform a psychometric evaluation of the Fecal Incontinence Quality of Life Scale in the Spanish language...
  40. ncbi request reprint [Endosonographic and manometric assessment of the internal anal sphincter in patients with chronic anal fissure]
    Marta Pascual
    Servicio de Cirugia General, Hospital del Mar, IMA, Barcelona, Spain
    Cir Esp 77:27-30. 2005
    ..The aims of the present study were to determine IAS thickness in patients with chronic anal fissure and to investigate the correlation between IAS thickness and anal resting pressure...
  41. ncbi request reprint Variation in clinical, manometric and endosonographic findings in anterior chronic anal fissure: a prospective study
    Marta Pascual
    Colorectal Surgery Unit, Department of Surgery, Hospital del Mar, Passeig Maritim 25 29, 08003, Barcelona, Spain
    Dig Dis Sci 53:21-6. 2008
    ..However, these differences were not statistically significant. We found correlation between mean maximal anal resting pressure and internal anal sphincter thickness in patients suffering from anterior chronic anal fissure...
  42. ncbi request reprint [EPICOLON project: contribution to the knowledge of Lynch syndrome and other familial or hereditary colorectal cancer]
    Antoni Castells
    Servicio de Gastroenterologia, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, Barcelona, Espana
    Med Clin (Barc) 128:55-60. 2007
  43. pmc Detection of BRAF V600E mutation in colorectal cancer: comparison of automatic sequencing and real-time chemistry methodology
    Susana Benlloch
    Unidad de Investigacion, Hospital General Universitario de Alicante, C Maestro Alonso 109, 03010 Alicante, Spain
    J Mol Diagn 8:540-3. 2006
    ..Because real-time chemistry methodology has advantages in cost, time, and labor, we consider it a valuable alternative to automatic direct sequencing, particularly for serial measurements...