Carlos Alonso-Villaverde

Summary

Affiliation: Hospital Universitario Sant Joan de Reus
Country: Spain

Publications

  1. ncbi Influence of inflammatory variables on intima-media thickness
    Blai Coll
    Stroke 39:e16. 2008
  2. doi [Physiopathology of cardiovascular disease in HIV-infected patients]
    Carlos Alonso-Villaverde Lozano
    Unidad VIH, Servicio de Medicina Interna, Centre de Recerca Biomedica, Hospital Universitario San Juan de Reus, Reus, Tarragona, Espana
    Enferm Infecc Microbiol Clin 27:33-9. 2009
  3. ncbi High-density lipoprotein concentrations relate to the clinical course of HIV viral load in patients undergoing antiretroviral therapy
    Carlos Alonso-Villaverde
    Servei de Medicina Interna of the Hospital Universitari de Sant Joan, Universitat Rovira i Virgili, Reus, Spain
    AIDS 17:1173-8. 2003
  4. ncbi Atherosclerosis in patients infected with HIV is influenced by a mutant monocyte chemoattractant protein-1 allele
    Carlos Alonso-Villaverde
    Servei de Medicina Interna, Hospital Universitari de Sant Joan, 43201 Reus, Spain
    Circulation 110:2204-9. 2004
  5. ncbi Turpentine-induced inflammation reduces the hepatic expression of the multiple drug resistance gene, the plasma cholesterol concentration and the development of atherosclerosis in apolipoprotein E deficient mice
    Monica Tous
    Centre de Recerca Biomedica, Institut de Recerca en Ciències de la Salut IRCIS, Hospital Universitari de Sant Joan, Reus, Spain
    Biochim Biophys Acta 1733:192-8. 2005
  6. doi Paraoxonase-1 gene haplotypes are associated with metabolic disturbances, atherosclerosis, and immunologic outcome in HIV-infected patients
    Sandra Parra
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut d Investigació Sanitària Pere Virgili, Lleida, Spain
    J Infect Dis 201:627-34. 2010
  7. ncbi The role of immunity and inflammation in the progression of atherosclerosis in patients with HIV infection
    Blai Coll
    Centre de Recerca Biomedica, Hospital Universitari Sant Joan, Reus, Spain
    Stroke 38:2477-84. 2007
  8. ncbi HIV-infected patients with lipodystrophy have higher rates of carotid atherosclerosis: the role of monocyte chemoattractant protein-1
    Blai Coll
    Servei de Medicina Interna, Hospital Universitari Sant Joan, Reus, Spain
    Cytokine 34:51-5. 2006
  9. pmc Infection with HIV and HCV enhances the release of fatty acid synthase into circulation: evidence for a novel indicator of viral infection
    Gerard Aragones
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain
    BMC Gastroenterol 10:92. 2010
  10. ncbi Manipulation of inflammation modulates hyperlipidemia in apolipoprotein E-deficient mice: a possible role for interleukin-6
    Monica Tous
    Centre de Recerca Biomedica, Institut de Recerca en Ciències de la Salut, IRCIS, Hospital Universitari de Sant Joan, C Sant Joan s n, 43201 Reus, Spain
    Cytokine 34:224-32. 2006

Collaborators

Detail Information

Publications56

  1. ncbi Influence of inflammatory variables on intima-media thickness
    Blai Coll
    Stroke 39:e16. 2008
  2. doi [Physiopathology of cardiovascular disease in HIV-infected patients]
    Carlos Alonso-Villaverde Lozano
    Unidad VIH, Servicio de Medicina Interna, Centre de Recerca Biomedica, Hospital Universitario San Juan de Reus, Reus, Tarragona, Espana
    Enferm Infecc Microbiol Clin 27:33-9. 2009
    ..Subsequently, the plaque will become complicated, either by rupture or erosion. Then, a juxtalesional thrombus is formed, where the platelet is activated...
  3. ncbi High-density lipoprotein concentrations relate to the clinical course of HIV viral load in patients undergoing antiretroviral therapy
    Carlos Alonso-Villaverde
    Servei de Medicina Interna of the Hospital Universitari de Sant Joan, Universitat Rovira i Virgili, Reus, Spain
    AIDS 17:1173-8. 2003
    ....
  4. ncbi Atherosclerosis in patients infected with HIV is influenced by a mutant monocyte chemoattractant protein-1 allele
    Carlos Alonso-Villaverde
    Servei de Medicina Interna, Hospital Universitari de Sant Joan, 43201 Reus, Spain
    Circulation 110:2204-9. 2004
    ..We investigated mutations in the monocyte chemoattractant protein-1 (MCP-1) and CCR-2 genes, which are known to control aspects of these pathways, to ascertain whether they are involved in atherogenesis in these patients...
  5. ncbi Turpentine-induced inflammation reduces the hepatic expression of the multiple drug resistance gene, the plasma cholesterol concentration and the development of atherosclerosis in apolipoprotein E deficient mice
    Monica Tous
    Centre de Recerca Biomedica, Institut de Recerca en Ciències de la Salut IRCIS, Hospital Universitari de Sant Joan, Reus, Spain
    Biochim Biophys Acta 1733:192-8. 2005
    ..Therefore, we conclude that mdr1 is an additional factor to consider in the complexity of alterations in cholesterol metabolism that occur in this model...
  6. doi Paraoxonase-1 gene haplotypes are associated with metabolic disturbances, atherosclerosis, and immunologic outcome in HIV-infected patients
    Sandra Parra
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut d Investigació Sanitària Pere Virgili, Lleida, Spain
    J Infect Dis 201:627-34. 2010
    ..We evaluated whether PON1 gene haplotypes influence the metabolic disturbances, presence of subclinical atherosclerosis, and virologic outcome associated with the infection...
  7. ncbi The role of immunity and inflammation in the progression of atherosclerosis in patients with HIV infection
    Blai Coll
    Centre de Recerca Biomedica, Hospital Universitari Sant Joan, Reus, Spain
    Stroke 38:2477-84. 2007
    ..Therefore, our hypothesis is that the progression of atherosclerosis in patients with HIV infection can be influenced by variations in genes implicated in both processes...
  8. ncbi HIV-infected patients with lipodystrophy have higher rates of carotid atherosclerosis: the role of monocyte chemoattractant protein-1
    Blai Coll
    Servei de Medicina Interna, Hospital Universitari Sant Joan, Reus, Spain
    Cytokine 34:51-5. 2006
    ..18, p=0.05). In summary, HIV-1-infected patients with clinically manifest LD are at higher risk for atherosclerosis and our observations support the relationship between inflammation and atherosclerotic disease...
  9. pmc Infection with HIV and HCV enhances the release of fatty acid synthase into circulation: evidence for a novel indicator of viral infection
    Gerard Aragones
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain
    BMC Gastroenterol 10:92. 2010
    ..The present study aimed to investigate whether serum FASN concentration may provide a direct link between HIV and/or HCV viral infections and lipid metabolic disorders commonly observed in HIV/HCV-infected patients...
  10. ncbi Manipulation of inflammation modulates hyperlipidemia in apolipoprotein E-deficient mice: a possible role for interleukin-6
    Monica Tous
    Centre de Recerca Biomedica, Institut de Recerca en Ciències de la Salut, IRCIS, Hospital Universitari de Sant Joan, C Sant Joan s n, 43201 Reus, Spain
    Cytokine 34:224-32. 2006
    ..We conclude that manipulation of inflammation-related mechanisms modulates lipid homeostasis and development of atherosclerotic plaque in rodents...
  11. pmc Effect of TNF-alpha genetic variants and CCR5 Delta 32 on the vulnerability to HIV-1 infection and disease progression in Caucasian Spaniards
    Sergi Veloso
    Hospital Universitari de Tarragona Joan XXIII, Tarragona, Spain
    BMC Med Genet 11:63. 2010
    ..Tumor necrosis factor alpha (TNF-alpha) is thought to be involved in the various immunogenetic events that influence HIV-1 infection...
  12. ncbi The stromal derived factor-1 mutated allele (SDF1-3'A) is associated with a lower incidence of atherosclerosis in HIV-infected patients
    Blai Coll
    Institut de Recerca en Ciències de la Salut, Hospital Universitari de Sant Joan, Reus, Spain
    AIDS 19:1877-83. 2005
    ..We tested the influence of SDF1-3'A on atherosclerosis in HIV-infected patients...
  13. ncbi Dietary cholesterol and differential monocyte chemoattractant protein-1 gene expression in aorta and liver of apo E-deficient mice
    Monica Tous
    Centre de Recerca Biomedica, Institut de Recerca en Ciències de la Salut IRCIS, Hospital Universitari de Sant Joan, Calle Sant Joan s n, 43201 Reus, Spain
    Biochem Biophys Res Commun 340:1078-84. 2006
    ..Therefore, the use of cholesterol-enriched diets should be carefully considered in the apolipoprotein E-deficient mice because they may trigger different stimuli and seriously hinder the interpretation of possible findings...
  14. ncbi PPARgamma Pro12Ala polymorphism in HIV-1-infected patients with HAART-related lipodystrophy
    Maria Saumoy
    Hospital Universitari Joan XXIII, Tarragona, Spain
    Curr HIV Res 7:533-40. 2009
    ..054). PPARgamma Pro12Ala SNP has no effect on the risk of developing lipodystrophy in HIV-1-infected patients treated with HAART. PPARgamma mRNA SAT expression appears decreased in lipodystrophy...
  15. pmc Decreased paraoxonase-1 activity is associated with alterations of high-density lipoprotein particles in chronic liver impairment
    Judit Marsillach
    Centre de Recerca Biomedica, Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, C, Sant Joan s n, 43201 Reus, Catalunya, Spain
    Lipids Health Dis 9:46. 2010
    ..Chronic liver diseases are characterized by decreased serum PON1 activity. The aim of the present study was to investigate the compositional changes in HDL that could influence PON1 activity in liver impairment...
  16. ncbi Serum paraoxonase-1 activity and concentration are influenced by human immunodeficiency virus infection
    Sandra Parra
    Servei de Medicina Interna, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, C Sant Joan s n, 43201 Reus, Spain
    Atherosclerosis 194:175-81. 2007
    ....
  17. doi Host-pathogen interactions in the development of metabolic disturbances and atherosclerosis in HIV infection: the role of CCL2 genetic variants
    Carlos Alonso-Villaverde
    Servei de Medicina Interna, Hospital Universitari de Sant Joan, IISPV, Universitat Rovira i Virgili, Reus, Spain
    Cytokine 51:251-8. 2010
    ..We evaluated whether CCL2 gene variants are associated with metabolic disturbances and plasma CCL2 levels in HIV-infected patients...
  18. ncbi Effect of genetic variants of CCR2 and CCL2 on the natural history of HIV-1 infection: CCL2-2518GG is overrepresented in a cohort of Spanish HIV-1-infected subjects
    Consuelo Vilades
    Department of Internal Medicine, Infectious Diseases and AIDS Research unit, Hospital Universitari de Tarragona Joan XXIII and Universitat Rovira i Virgili, Tarragona, Spain
    J Acquir Immune Defic Syndr 44:132-8. 2007
    ..Our aim was to determine whether functionally active CCR2 and CCL2 genetic variants influence the risk of infection and disease progression in a cohort of white Spaniards...
  19. doi Human immunodeficiency virus-infection induces major changes in high-density lipoprotein particle size distribution and composition: the effect of antiretroviral treatment and disease severity
    Gerard Aragones
    Centre de Recerca Biomedica, Hospital Universitari Sant Joan, Institut d Investigació Sanitària Pere Virgili IISPV, Reus, Universitat Rovira i Virgili, Spain
    Clin Chem Lab Med 48:1147-52. 2010
    ..We evaluated whether HIV infection and antiretroviral treatment promotes changes in cholesterol distribution among subpopulations of HDL particles of defined sizes...
  20. doi Lipodystrophy and insulin resistance in combination antiretroviral treated HIV-1-infected patients: implication of resistin
    Xavier Escote
    Hospital Universitari de Tarragona Joan XXIII, IISPV, Universitat Rovira i Virgili, Tarragona, Spain
    J Acquir Immune Defic Syndr 57:16-23. 2011
    ..We determined whether the resistin (rest) -420C>G single-nucleotide polymorphism and plasma resistin are associated with the development of lipodystrophy and metabolic disturbances in HIV-1-infected patients treated with cART...
  21. pmc Methodological constraints in interpreting serum paraoxonase-1 activity measurements: an example from a study in HIV-infected patients
    Sandra Parra
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut d Investigació Sanitària Pere Virgili, Reus, Catalunya, Spain
    Lipids Health Dis 9:32. 2010
    ..In the present study, we explored the relationships between the circulating levels of PON1 and MCP-1 in human immunodeficiency virus-infected patients in relation to the multifunctional capabilities of PON1...
  22. ncbi The influence of HIV infection on the correlation between plasma concentrations of monocyte chemoattractant protein-1 and carotid atherosclerosis
    Jorge Joven
    Centre de Recerca Biomèdica dels Laboratoris Clínics, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, C Sant Joan s n, 43201 Reus, Spain
    Clin Chim Acta 368:114-9. 2006
    ..Little is known of the factors that may influence plasma MCP-1 concentrations...
  23. ncbi Deficiency in monocyte chemoattractant protein-1 modifies lipid and glucose metabolism
    Anna Rull
    Centre de Recerca Biomedica, Institut de Recerca en Ciències de la Salut IRCIS, Hospital Universitari de Sant Joan, C Sant Joan s n, 43201 Reus, Spain
    Exp Mol Pathol 83:361-6. 2007
    ..Therefore, the regulatory mechanisms influenced by MCP-1 should be fully ascertained to understand the metabolic consequences of inflammation and before considering MCP-1 as a therapeutic target...
  24. pmc Antiretroviral treatment-induced dyslipidemia in HIV-infected patients is influenced by the APOC3-related rs10892151 polymorphism
    Gerard Aragones
    Centre de Recerca Biomedica, Universitat Rovira i Virgili, Institut d Investigació Sanitària Pere Virgili, Reus, Spain
    BMC Med Genet 12:120. 2011
    ....
  25. pmc The deleterious influence of tenofovir-based therapies on the progression of atherosclerosis in HIV-infected patients
    Gerard Aragones
    Unitat de Recerca Biomedica, Hospital Universitari Sant Joan, Institut Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain
    Mediators Inflamm 2012:372305. 2012
    ....
  26. pmc Serum paraoxonase-3 concentration in HIV-infected patients. Evidence for a protective role against oxidation
    Gerard Aragones
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain
    J Lipid Res 53:168-74. 2012
    ..Long-term, prospective studies are needed to confirm the possible influence of this enzyme on the course of this disease and its possible utility as an analytical biomarker...
  27. doi Expression of cytokine genes in the aorta is altered by the deficiency in MCP-1: effect of a high-fat, high-cholesterol diet
    Anna Rull
    Centre de Recerca Biomedica, Hospital Universitari Sant Joan de Reus, IISPV Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, C Sant Joan s n, Reus, Spain
    Cytokine 50:121-8. 2010
    ..However, chemokines are redundant. Consequently, the protective effect of MCP-1 deficiency may be mediated by changes in other cytokine signals...
  28. ncbi The efavirenz-induced increase in HDL-cholesterol is influenced by the multidrug resistance gene 1 C3435T polymorphism
    Carlos Alonso-Villaverde
    Servei de Medicina Interna, Hospital Universitari de Sant Joan, Reus, Spain
    AIDS 19:341-2. 2005
    ..Efavirenz treatment increased HDL-cholesterol. The changes in concentrations appeared to be influenced by the MDR-1 gene polymorphism, in which CC > CT > TT...
  29. doi Hepatic monocyte chemoattractant protein-1 is upregulated by dietary cholesterol and contributes to liver steatosis
    Anna Rull
    Centre de Recerca Biomedica, Hospital Universitari Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, C Sant Joan s n, 43201 Reus, Spain
    Cytokine 48:273-9. 2009
    ....
  30. ncbi The results in rodent models of atherosclerosis are not interchangeable: the influence of diet and strain
    Jorge Joven
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Carrer Sant Joan s n, 43201 Reus, Spain
    Atherosclerosis 195:e85-92. 2007
    ..The divergent responses indicate that the choice of the diet and the model should be carefully considered in atherosclerosis studies and extrapolations interpreted with caution...
  31. doi Serum fatty acid synthase concentration is increased in patients with hepatitis viral infection and may assist in the prediction of liver steatosis
    Jorge Joven
    Centre de Recerca Biomedica, IISPV, Universitat Rovira i Virgili, Reus, Spain
    J Clin Virol 51:199-201. 2011
    ..FASN can also be found in circulation and is significantly increased in HIV-infected individuals, especially if they are co-infected with hepatitis C virus (HCV)...
  32. doi Interrelationships between paraoxonase-1 and monocyte chemoattractant protein-1 in the regulation of hepatic inflammation
    Jordi Camps
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, C Sant Joan s n, 43201 Reus, Catalunya, Spain
    Adv Exp Med Biol 660:5-18. 2010
    ..The current review summarises experiments suggesting how paraoxonase-1 activity and expression are altered in liver diseases, and their relationships with the monocyte chemoattractant protein-1 and inflammation...
  33. doi Differential response of two models of genetically modified mice fed with high fat and cholesterol diets: relationship to the study of non-alcoholic steatohepatitis
    Fernando Rodríguez-Sanabria
    Centre de Recerca Biomedica, Hospital Universitari Sant Joan de Reus, Universitat Rovira i Virgili, Reus, Spain
    Mol Cell Biochem 343:59-66. 2010
    ..These changes were accompanied by a differential expression of selected members of the MAPK family and PPARs in the liver...
  34. ncbi Human Duffy blood group alloantigen system influences the measurement of monocyte chemoattractant protein-1 (MCP-1) in serum but not in plasma
    Gerard Aragones
    Centre de Recerca Biomedica, Universitat Rovira i Virgili, Hospital Universitari de Sant Joan, IISPV, Reus, Spain
    Clin Lab 58:185-8. 2012
    ..We explored whether the Asp42Gly polymorphism (rs12075) in the DARC gene represents a confounding factor in the interpretation of monocyte chemoattractant protein-1 (MCP-1) concentration in circulating blood...
  35. ncbi Protease inhibitor-associated dyslipidemia in HIV-infected patients is strongly influenced by the APOA5-1131T->C gene variation
    Montse Guardiola
    Institut de Recerca en Ciències de la Salut, Hospital Universitari de Sant Joan de Reus, Universitat Rovira i Virgili, Reus, Spain
    Clin Chem 52:1914-9. 2006
    ..The apolipoprotein A-V (APOA5) gene, which affects VLDL production and lipolysis, may play a role in PI-induced hyperlipidemia, particularly in individuals with the APOA5-1131T-->C genotype...
  36. pmc A possible role for CCR5 in the progression of atherosclerosis in HIV-infected patients: a cross-sectional study
    Laura Fernández-Sender
    Unitat de Recerca Biomedica, Hospital Universitari Sant Joan, Institut d Investigació Sanitària Pere Virgili IISPV, Universitat Rovira i Virgili, Reus, Spain, Carrer Sant Llorenc 21, Reus 43201, Spain
    AIDS Res Ther 10:11. 2013
    ..We hypothesised that the expression of chemokine receptors in circulating leukocytes is associated with the rate of atherosclerosis progression in HIV-infected patients...
  37. doi Plant-derived polyphenols regulate expression of miRNA paralogs miR-103/107 and miR-122 and prevent diet-induced fatty liver disease in hyperlipidemic mice
    Jorge Joven
    Unitat de Recerca Biomèdica URB CRB, Institut d Investigació Sanitària Pere Virgili IISPV, Universitat Rovira i Virgili, Reus, Spain
    Biochim Biophys Acta 1820:894-9. 2012
    ..MicroRNAs have the potential for clinical application. Probable modulation by plant-derived polyphenols might open preventive measures using simple dietary recommendations...
  38. pmc PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways
    Jordi Camps
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Spain
    PPAR Res 2012:616371. 2012
    ..We also describe recent lines of evidence suggesting links between PON1 and MCP-1 and how their production may be regulated by PPAR...
  39. ncbi The fatty acid binding protein-4 (FABP4) is a strong biomarker of metabolic syndrome and lipodystrophy in HIV-infected patients
    Blai Coll
    Centre de Recerca Biomedica, Hospital Universitari Sant Joan, Universitat Rovira i Virgili, 43201 Reus, Tarragona, Spain
    Atherosclerosis 199:147-53. 2008
    ..Fatty acid binding protein-4 (FABP4) is an emerging biomarker for metabolic-related disturbances. We aimed to study FABP4 as a marker of metabolic syndrome (MS) or lipodystrophy (LD) in HIV patients...
  40. doi The IL-6 system in HIV-1-infection and in HAART-related fat redistribution syndromes
    Maria Saumoy
    Hospital Universitari de Tarragona Joan XXIII, Universitat Rovira i Virgili, Tarragona, Spain
    AIDS 22:893-6. 2008
    ..The IL-6 -174 G>C genotype distribution and allele frequencies, SAT IL-6 mRNA expression and IL-6 plasma levels were non-significantly different between HIV-1-infected patients with and without lipodystrophy...
  41. pmc Ubiquitous transgenic overexpression of C-C chemokine ligand 2: a model to assess the combined effect of high energy intake and continuous low-grade inflammation
    Esther Rodríguez-Gallego
    Unitat de Recerca Biomedica, Hospital Universitari Sant Joan, Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Carrer Sant Llorenc 21, 43201 Reus, Spain Campus of International Excellence Southern Catalonia, Spain
    Mediators Inflamm 2013:953841. 2013
    ..These results raise a number of mechanistic questions for future study. ..
  42. ncbi Effects of rosiglitazone and metformin on postprandial paraoxonase-1 and monocyte chemoattractant protein-1 in human immunodeficiency virus-infected patients with lipodystrophy
    Blai Coll
    Servei de Medicina Interna and Centre de Recerca Biomèdica, Hospital Universitari, de Sant Joan, Reus, Spain
    Eur J Pharmacol 544:104-10. 2006
    ..To decrease insulin resistance results in a higher anti-oxidant and consequent lower pro-inflammatory action of HDL. This may confer protection against accelerated atherosclerosis in these patients...
  43. ncbi Hibiscus sabdariffa extract lowers blood pressure and improves endothelial function
    Jorge Joven
    Unitat de Recerca Biomedica, Hospital Universitari Sant Joan, Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Campus of International Excellence Southern Catalonia, Reus, Spain
    Mol Nutr Food Res 58:1374-8. 2014
    ..Notably, polyphenols induced a favorable endothelial response that should be considered in the management of metabolic cardiovascular risks. ..
  44. ncbi Ezetimibe effectively decreases LDL-cholesterol in HIV-infected patients
    Blai Coll
    Centre de Recerca Biomedica, Reus, Spain
    AIDS 20:1675-7. 2006
    ..003) 20% reduction in the concentration of LDL-cholesterol, similar to that observed with fluvastatin (24%, P between groups 0.70). We concluded that ezetimibe monotherapy effectively decreases LDL-cholesterol in HIV-infected patients...
  45. ncbi Association of a polymorphism in the promoter of the cellular retinoic acid-binding protein II gene (CRABP2) with increased circulating low-density lipoprotein cholesterol
    Juliana Salazar
    Institut de Recerca en Ciències de la Salut, Hospital Universitari Sant Joan, Universitat Rovira i Virgili, Reus, Spain
    Clin Chem Lab Med 45:615-20. 2007
    ....
  46. doi Metabolic stress in infected cells may represent a therapeutic target for human immunodeficiency virus infection
    Carlos Alonso-Villaverde
    Unitat de Recerca Biomèdica URB, IISPV, Universitat Rovira i Virgili, Reus, Spain
    Med Hypotheses 81:125-30. 2013
    ..We suggest that the combination of vorinostat, chloroquine and metformin should be combined with ART to pursue viral eradication in infected cells...
  47. ncbi The role of circulating monocyte chemoattractant protein-1 as a marker of hepatic inflammation in patients with chronic liver disease
    Judit Marsillach
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, C Sant Joan s n, 43201 Reus, Spain
    Clin Biochem 38:1138-40. 2005
    ..These results underline the role of monocyte chemoattractant protein-1 in the pathogenesis of liver impairment and suggest that this chemokine may be a reliable marker of inflammation in hepatic derangements...
  48. doi Serum concentrations of extracellular fatty acid synthase in patients with steatohepatitis
    Judit Marsillach
    Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, Institut d Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain
    Clin Chem Lab Med 47:1097-9. 2009
    ..The present study aimed to assess whether serum FASN concentrations are altered in patients with chronic liver disease, and to investigate whether its measurement may be a useful tool in the clinical evaluation of this derangement...
  49. ncbi Monocyte chemoattractant protein-1 and atherosclerosis: is there room for an additional biomarker?
    Blai Coll
    Centre de Recerca Biomedica, Hospital Universitari Sant Joan, 43201, Reus, Spain
    Clin Chim Acta 383:21-9. 2007
    ....
  50. doi Polyphenols and the modulation of gene expression pathways: can we eat our way out of the danger of chronic disease?
    Jorge Joven
    a Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, IISPV, Universitat Rovira i Virgili, Calle Sant Llorenç 21, 43201, Reus, Spain
    Crit Rev Food Sci Nutr 54:985-1001. 2014
    ....
  51. doi A study of fatty acid binding protein 4 in HIV-1 infection and in combination antiretroviral therapy-related metabolic disturbances and lipodystrophy
    X Escote
    Joan XXIII University Hospital of Tarragona, IISPV, Rovira i Virgili University, Tarragona, Spain
    HIV Med 12:428-37. 2011
    ....
  52. ncbi Carotid intima-media thickness course in HIV-infected patients: beyond classical cardiovascular risk factors
    Blai Coll
    AIDS 21:1989-90. 2007
  53. doi Didanosine, lamivudine, and efavirenz versus zidovudine, lamivudine, and efavirenz for the initial treatment of HIV type 1 infection: final analysis (48 weeks) of a prospective, randomized, noninferiority clinical trial, GESIDA 3903
    Juan Berenguer
    Hospital Gregorio Maranon, Madrid, Spain
    Clin Infect Dis 47:1083-92. 2008
    ..The combination of didanosine, lamivudine, and efavirenz (ddI/3TC/EFV) for the initial treatment of human immunodeficiency virus type 1 (HIV-1) infection has been insufficiently analyzed in clinical trials...
  54. ncbi Carotid intima-media thickness: assessment of sub-clinical atherosclerosis in HIV-infected patients
    Blai Coll
    AIDS 19:1936-7. 2005
  55. ncbi [Micronutrients in HIV-infection and the relationship with the inflammatory response]
    Maria Jesus Jimenez-Exposito
    Unidad de Nutrición Humana Facultad de Medicina y Ciencias de la Salud Universitat Rovira y Virgili Reus Tarragona Spain
    Med Clin (Barc) 119:765-9. 2002
    ..Our aim was to measure the plasma concentrations of various vitamins and micronutrients involved in the immune response and antioxidant systems of an HIV+ population and to determine how they are related to the inflammatory response...