Felix Gutierrez

Summary

Country: Spain

Publications

  1. ncbi request reprint Pulmonary mycetoma caused by an atypical isolate of Paecilomyces species in an immunocompetent individual: case report and literature review of Paecilomyces lung infections
    F Gutierrez
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Camí de la Almazara S N, 03203, Elche, Alicante, Spain
    Eur J Clin Microbiol Infect Dis 24:607-11. 2005
  2. ncbi request reprint Osteonecrosis in patients infected with HIV: clinical epidemiology and natural history in a large case series from Spain
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    J Acquir Immune Defic Syndr 42:286-92. 2006
  3. pmc Gender differential on characteristics and outcome of leprosy patients admitted to a long-term care rural hospital in South-Eastern Ethiopia
    Jose M Ramos
    Gambo General Rural Hospital, Shashemane, Ethiopia
    Int J Equity Health 11:56. 2012
  4. pmc Contribution of interferon gamma release assays testing to the diagnosis of latent tuberculosis infection in HIV-infected patients: a comparison of QuantiFERON-TB Gold In Tube, T-SPOT.TB and tuberculin skin test
    Jose M Ramos
    Infectious Diseases Unit, Hospital General Universitario de Elche, Camino de la Almazara, 12, 03203, Elche, Alicante, Spain
    BMC Infect Dis 12:169. 2012
  5. doi request reprint [Methods for determination of HIV tropism and their clinical use]
    Felix Gutierrez
    Servicio de Enfermedades Infecciosas, Hospital General Universitario de Elche, Alicante, Departamento de Medicina, Universidad Miguel Hernandez, Alicante, Espana
    Enferm Infecc Microbiol Clin 29:45-50. 2011
  6. ncbi request reprint Epidemiology of community-acquired pneumonia in adult patients at the dawn of the 21st century: a prospective study on the Mediterranean coast of Spain
    F Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Madrid, Spain
    Clin Microbiol Infect 11:788-800. 2005
  7. pmc Clinical outcome of HIV-infected patients with sustained virologic response to antiretroviral therapy: long-term follow-up of a multicenter cohort
    Felix Gutierrez
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Universidad Miguel Hernandez, Alicante, Spain
    PLoS ONE 1:e89. 2006
  8. ncbi request reprint Occult lymphadenopathic Kaposi's sarcoma associated with severe pulmonary hypertension: A clinical hint about the potential role of HHV-8 in HIV-related pulmonary hypertension?
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    J Clin Virol 37:79-82. 2006
  9. ncbi request reprint Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring
    Felix Gutierrez
    Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    Clin Infect Dis 41:1648-53. 2005
  10. ncbi request reprint The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Camí de la Almazara S N, 03203 Elche, Alicante, Spain
    J Infect 53:166-74. 2006

Detail Information

Publications85

  1. ncbi request reprint Pulmonary mycetoma caused by an atypical isolate of Paecilomyces species in an immunocompetent individual: case report and literature review of Paecilomyces lung infections
    F Gutierrez
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Camí de la Almazara S N, 03203, Elche, Alicante, Spain
    Eur J Clin Microbiol Infect Dis 24:607-11. 2005
    ..The antifungal susceptibility profile was also determined. This report underscores the increasing importance of Paecilomyces species in human infections. Paecilomyces should be included among the etiological agents of pulmonary mycetoma...
  2. ncbi request reprint Osteonecrosis in patients infected with HIV: clinical epidemiology and natural history in a large case series from Spain
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    J Acquir Immune Defic Syndr 42:286-92. 2006
    ..There is a paucity of data on clinical epidemiology of osteonecrosis in HIV-infected patients. We aimed to describe patients' characteristics and natural history of this poorly known condition...
  3. pmc Gender differential on characteristics and outcome of leprosy patients admitted to a long-term care rural hospital in South-Eastern Ethiopia
    Jose M Ramos
    Gambo General Rural Hospital, Shashemane, Ethiopia
    Int J Equity Health 11:56. 2012
    ..We assess the gender differences in leprosy cases admitted to a rural referral hospital in Ethiopia for 7 and a half years...
  4. pmc Contribution of interferon gamma release assays testing to the diagnosis of latent tuberculosis infection in HIV-infected patients: a comparison of QuantiFERON-TB Gold In Tube, T-SPOT.TB and tuberculin skin test
    Jose M Ramos
    Infectious Diseases Unit, Hospital General Universitario de Elche, Camino de la Almazara, 12, 03203, Elche, Alicante, Spain
    BMC Infect Dis 12:169. 2012
    ..TB for the diagnosis of LTBI in a diverse cohort of HIV-infected patients...
  5. doi request reprint [Methods for determination of HIV tropism and their clinical use]
    Felix Gutierrez
    Servicio de Enfermedades Infecciosas, Hospital General Universitario de Elche, Alicante, Departamento de Medicina, Universidad Miguel Hernandez, Alicante, Espana
    Enferm Infecc Microbiol Clin 29:45-50. 2011
    ....
  6. ncbi request reprint Epidemiology of community-acquired pneumonia in adult patients at the dawn of the 21st century: a prospective study on the Mediterranean coast of Spain
    F Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Madrid, Spain
    Clin Microbiol Infect 11:788-800. 2005
    ..Greater effort should be made to improve identification methods for microbial pathogens causing CAP...
  7. pmc Clinical outcome of HIV-infected patients with sustained virologic response to antiretroviral therapy: long-term follow-up of a multicenter cohort
    Felix Gutierrez
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Universidad Miguel Hernandez, Alicante, Spain
    PLoS ONE 1:e89. 2006
    ..Limited information exists on long-term prognosis of patients with sustained virologic response to antiretroviral therapy. We aimed to assess predictors of unfavorable clinical outcome in patients who maintain viral suppression with HAART...
  8. ncbi request reprint Occult lymphadenopathic Kaposi's sarcoma associated with severe pulmonary hypertension: A clinical hint about the potential role of HHV-8 in HIV-related pulmonary hypertension?
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    J Clin Virol 37:79-82. 2006
    ..Coinfection with HHV-8 and occult lymphadenopatic KS should be considered in HIV-infected patients developing PH...
  9. ncbi request reprint Prediction of neuropsychiatric adverse events associated with long-term efavirenz therapy, using plasma drug level monitoring
    Felix Gutierrez
    Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    Clin Infect Dis 41:1648-53. 2005
    ..We aimed to determine whether monitoring the plasma concentration of efavirenz could predict neuropsychiatric adverse events associated with long-term therapy with efavirenz...
  10. ncbi request reprint The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Camí de la Almazara S N, 03203 Elche, Alicante, Spain
    J Infect 53:166-74. 2006
    ..To determine the population-based incidence of community-acquired pneumonia (CAP) in adults and to assess the relative importance of age and gender on the incidence of infections caused by different microbial pathogens...
  11. ncbi request reprint The role of HIV and antiretroviral therapy in bone disease
    Felix Gutierrez
    Infectious Diseases Unit, Hospital General Universitario, Elche, Spain
    AIDS Rev 13:109-18. 2011
    ..Given the complex interaction between HIV and drugs in causing low bone mineral density, optimization of antiretroviral therapy and preemptive strategies aimed to prevent bone loss during therapy may be of paramount importance...
  12. ncbi request reprint Community-acquired pneumonia of mixed etiology: prevalence, clinical characteristics, and outcome
    F Gutierrez
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Camí de la Almazara S N, 03203 Elche, Alicante, Spain
    Eur J Clin Microbiol Infect Dis 24:377-83. 2005
    ..3% vs. 18.6%; OR=2.84; p=0.02). Community-acquired pneumonia of mixed etiology is uncommon. Patients with mixed pneumonia are more likely to have underlying medical conditions, and they may have a more severe course of disease...
  13. ncbi request reprint Evaluation of the immunochromatographic Binax NOW assay for detection of Streptococcus pneumoniae urinary antigen in a prospective study of community-acquired pneumonia in Spain
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    Clin Infect Dis 36:286-92. 2003
    ..4% and a specificity of 89.7%. Testing concentrated urine samples with the ICT may be a useful technique for rapid diagnosis of pneumococcal pneumonia in adults with CAP...
  14. ncbi request reprint Lopinavir plasma concentrations and changes in lipid levels during salvage therapy with lopinavir/ritonavir-containing regimens
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    J Acquir Immune Defic Syndr 33:594-600. 2003
    ..To determine whether an association existed between lopinavir (LPV) plasma concentrations and changes in lipid levels...
  15. ncbi request reprint Changes in body fat composition after 1 year of salvage therapy with lopinavir/ritonavir-containing regimens and its relationship with lopinavir plasma concentrations
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    Antivir Ther 9:105-13. 2004
    ..To determine whether an association existed between lopinavir (LPV) plasma concentrations and changes in body fat composition...
  16. ncbi request reprint Patients' characteristics and clinical implications of suboptimal CD4 T-cell gains after 1 year of successful antiretroviral therapy
    Felix Gutierrez
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Universidad Miguel Hernandez, Alicante, Spain
    Curr HIV Res 6:100-7. 2008
    ..Patients with suboptimal response had a higher mortality over time, mainly due to diseases other than AIDS-defining events...
  17. ncbi request reprint Delay in the initiation of HAART, poorer virological response, and higher mortality among HIV-infected injecting drug users in Spain
    M Angeles Rodríguez-Arenas
    Departmento de Salud Pública, Universidad Miguel Hernandez, San Juan Alicante, Spain
    AIDS Res Hum Retroviruses 22:715-23. 2006
    ..There is a need to extend the programs in order to enhance access and adherence of IDUs to HAART and consider the treatment of drug addiction as an integral part of the treatment for HIV infection...
  18. doi request reprint Substitution of raltegravir for ritonavir-boosted protease inhibitors in HIV-infected patients: the SPIRAL study
    Esteban Martinez
    Infectious Diseases Unit, Hospital Clínic Institut d Investigaciones Biomèdiques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    AIDS 24:1697-707. 2010
    ..Switching to raltegravir in selected patients treated with ritonavir-boosted protease inhibitors may result in similar efficacy and lower plasma lipids...
  19. ncbi request reprint Update on clinical and methodological recommendations for genotypic determination of HIV tropism to guide the usage of CCR5 antagonists
    Eva Poveda
    Infectious Diseases Department, Hospital Carlos III, Madrid, Spain
    AIDS Rev 14:208-17. 2012
    ..This review updates clinical and methodological recommendations for genotypic determination of HIV tropism to guide therapeutic decisions using CCR5 antagonists, considering the most recently reported data...
  20. doi request reprint High-density lipoprotein cholesterol in HIV-infected patients: evidence for an association with HIV-1 viral load, antiretroviral therapy status, and regimen composition
    Enrique Bernal
    Infectious Diseases Unit, Hospital General Universitario de Elche, Department of Clinical Medicine, Universidad Miguel Hernandez, Elche, Spain
    AIDS Patient Care STDS 22:569-75. 2008
    ..Undetectable viral load and treatment with NNRTIs are protective factors, whereas hypertriglyceridemia is directly associated with low HDL-C levels...
  21. doi request reprint [HIV infection in immigrants in Spain: Epidemiological characteristics and clinical presentation in the CoRIS Cohort (2004-2006)]
    Ana María Caro-Murillo
    Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, Ministerio de Ciencia e Innovacion, Madrid, Espana
    Enferm Infecc Microbiol Clin 27:380-8. 2009
    ..We describe the sociodemographic, epidemiological, and clinical characteristics of a cohort of naïve HIV-infected subjects (CoRIS cohort) according to their place of origin...
  22. ncbi request reprint Risk factors, CD4 long-term evolution and mortality of HIV-infected patients who persistently maintain low CD4 counts, despite virological response to HAART
    Yolanda M Pacheco
    Servicio de Enfermedades Infecciosas, Hospital Universitario Virgen del Rocio, Sevilla, Spain
    Curr HIV Res 7:612-9. 2009
    ....
  23. ncbi request reprint Influence of antiretroviral therapy on oxidative stress and cardiovascular risk: a prospective cross-sectional study in HIV-infected patients
    Mar Masia
    Infectious Diseases Unit, Hospital General Universitario de Elche, Universidad Miguel Hernandez, Elche, Spain
    Clin Ther 29:1448-55. 2007
    ..OS is increased among HIV-infected patients, but whether it implicates a higher risk for cardiovascular disease or the influence of antiretroviral therapy (ART) on OS remains unknown...
  24. ncbi request reprint Avascular necrosis of the bone in HIV-infected patients: incidence and associated factors
    Felix Gutierrez
    Unidades de Enfermedades Infecciosas de la Comunidad Valenciana y Murcia, Hospital General Universitario de Elche, Elche, Spain
    AIDS 16:481-3. 2002
  25. ncbi request reprint [Insulin resistance in HIV-infected patients receiving long-term therapy with efavirenz, lopinavir/ritonavir and atazanavir]
    Enrique Bernal
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Elche, Alicante, Espana
    Med Clin (Barc) 129:252-4. 2007
    ..To assess the presence of insulin resistance in human immunodeficiency virus (HIV)-infected patients receiving long-term antiretroviral therapy...
  26. doi request reprint Early changes in parathyroid hormone concentrations in HIV-infected patients initiating antiretroviral therapy with tenofovir
    Mar Masia
    Infectious Diseases Unit, Hospital General Universitario de Elche, Alicante, Spain
    AIDS Res Hum Retroviruses 28:242-6. 2012
    ..Suboptimal baseline 25(OH)D levels increase the risk of developing secondary hyperparathyroidism among tenofovir users...
  27. ncbi request reprint Low frequency of renal function impairment during one-year of therapy with tenofovir-containing regimens in the real-world: a case-control study
    Sergio Padilla
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    AIDS Patient Care STDS 19:421-4. 2005
    ..The use of TDF in clinical practice during a 12-month period is associated with low risk of mild renal failure. Further studies to assess long-term renal safety of this drug are needed...
  28. ncbi request reprint Differences in the causes of death of HIV-positive patients in a cohort study by data sources and coding algorithms
    Victoria Hernando
    Red de Investigación en SIDA, Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, Madrid, Spain
    AIDS 26:1829-34. 2012
    ....
  29. doi request reprint A highly sensitive and specific model for predicting HIV-1 tropism in treatment-experienced patients combining interpretation of V3 loop sequences and clinical parameters
    Victoria Sanchez
    Infectious Diseases Unit, Hospital General Universitario de Elche, Alicante, Spain
    J Acquir Immune Defic Syndr 56:51-8. 2011
    ..Genotypic assays may provide an easier alternative, but their sensitivity remains low. We hypothesize that combining clinical data with V3 sequences may improve the diagnostic accuracy of genotypic tools...
  30. pmc Broad phenotypic cross-resistance to elvitegravir in HIV-infected patients failing on raltegravir-containing regimens
    Carolina Garrido
    Hospital Carlos III, Madrid, Spain
    Antimicrob Agents Chemother 56:2873-8. 2012
    ..There is broad cross-resistance between RAL and EVG, which should preclude their sequential use. Resistance to EVG seems to be more frequent and might be more influenced by integrase variability...
  31. doi request reprint Plasma raltegravir exposure influences the antiviral activity and selection of resistance mutations
    Carolina Garrido
    Infectious Diseases Department, Hospital Carlos III, Madrid, Spain
    AIDS Res Hum Retroviruses 28:156-64. 2012
    ..001). Undetectable RAL C(t) was seen only in patients failing RAL without integrase resistance mutations (64.1% of them). RAL failures in the absence of integrase resistance mutations mainly reflect poor drug compliance...
  32. doi request reprint Endothelial function is impaired in HIV-infected patients with lipodystrophy
    Mar Masia
    Infectious Diseases Unit, Hospital General Universitario de Elche, Department of Clinical Medicine, University Miguel Hernandez, Elche, Alicante, Spain
    Antivir Ther 15:101-10. 2010
    ..We evaluated endothelial dysfunction, an early event in the development of atherosclerosis, and pro-atherosclerotic plasma biomarkers in HIV-infected patients with lipodystrophy...
  33. pmc Early changes in inflammatory and pro-thrombotic biomarkers in patients initiating antiretroviral therapy with abacavir or tenofovir
    Sergio Padilla
    Infectious Diseases Unit, Hospital General Universitario de Elche, Department of Clinical Medicine, University Miguel Hernandez, Elche, Alicante, Spain
    BMC Infect Dis 11:40. 2011
    ..We evaluated longitudinal changes in pro-atherosclerotic biomarkers in patients initiating abacavir or tenofovir...
  34. ncbi request reprint Ultrasonography and anthropometry for measuring regional body fat in HIV-infected patients
    Sergio Padilla
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    Curr HIV Res 5:459-66. 2007
    ..Ultrasonography and anthropometry are fairly accurate and reproducible methods for the evaluation of intraabdominal and peripheral fat. Its role for assessing facial fat seems to be more limited...
  35. doi request reprint [HIV-related cardiovascular risk factors]
    Mar Masia
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Alicante, Espana
    Enferm Infecc Microbiol Clin 27:17-23. 2009
    ..Although the association of HIV with cardiovascular risk is controversial, coinfection with hepatitis C infection has been associated with a higher frequency of insulin resistance and acute myocardial infarction in some cohorts...
  36. doi request reprint Association between IL28B gene polymorphisms and plasma HCV-RNA levels in HIV/HCV-co-infected patients
    Pablo Labarga
    Infectious Diseases Department, Hospital Carlos III, Madrid, Spain
    AIDS 25:761-6. 2011
    ..This observation has been reproduced in HIV-co-infected individuals. Controversy exists about the impact of IL28B alleles on HCV load...
  37. ncbi request reprint Serum concentrations of lipopolysaccharide-binding protein as a biochemical marker to differentiate microbial etiology in patients with community-acquired pneumonia
    Mar Masia
    Infectious Diseases Unit, Internal Medicine Department, Clinical Chemistry Service, Hospital General Universitario de Elche, Alicante, Spain
    Clin Chem 50:1661-4. 2004
  38. doi request reprint Risk, predictors, and mortality associated with non-AIDS events in newly diagnosed HIV-infected patients: role of antiretroviral therapy
    Mar Masia
    Infectious Diseases Unit, Hospital General Universitario de Elche, Spain
    AIDS 27:181-9. 2013
    ..We aimed to characterize non-AIDS events (NAEs) occurring in newly diagnosed HIV-infected patients in a contemporary cohort...
  39. doi request reprint [The Cohort of the Spanish HIV Research Network (CoRIS) and its associated biobank; organizational issues, main findings and losses to follow-up]
    Paz Sobrino-Vegas
    Red de Investigación en SIDA, Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, Madrid, Espana
    Enferm Infecc Microbiol Clin 29:645-53. 2011
    ....
  40. doi request reprint Abacavir-based therapy does not affect biological mechanisms associated with cardiovascular dysfunction
    Esteban Martinez
    Infectious Diseases Unit, Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, C Villarroel 170, 08036 Barcelona, Spain
    AIDS 24:F1-9. 2010
    ..To assess the effects of initiating abacavir-containing therapy on plasma lipids and cardiovascular biomarkers...
  41. doi request reprint Negative effect of immunosuppressive therapy in the performance of the QuantiFERON gold in-tube test in patients with immune-mediated inflammatory diseases
    Jose M Ramos
    Infectious Diseases Unit, Hospital General Universitario de Elche, Camí de l Almassara 11, 3203, Elche, Alicante, Spain
    Clin Exp Med 13:177-86. 2013
    ..085; κ = 0.041, respectively). Immunosuppressive therapy affects negatively QFG performance. In patients with immune-mediated inflammatory diseases, QFG may have a limited role for screening of latent tuberculosis infection...
  42. ncbi request reprint Genotypic determination of HIV tropism - clinical and methodological recommendations to guide the therapeutic use of CCR5 antagonists
    Eva Poveda
    Infectious Diseases Department, Hospital Carlos III, Madrid, Spain
    AIDS Rev 12:135-48. 2010
    ..This review summarizes clinical and methodological recommendations for the genotypic determination of HIV tropism to guide therapeutic decisions with CCR5 antagonists in HIV therapeutics...
  43. doi request reprint Endothelial function in HIV-infected patients switching from a boosted protease inhibitor-based regimen to raltegravir: a substudy of the SPIRAL study
    Mar Masia
    Infectious Diseases Unit, Hospital General Universitario de Elche, University Miguel Hernandez, Alicante, Spain
    J Antimicrob Chemother 68:409-13. 2013
    ..We aimed to assess the effect on endothelial function of switching from a ritonavir-boosted protease inhibitor (PI/r)-based regimen to raltegravir...
  44. pmc Performance of genotypic algorithms for predicting HIV-1 tropism measured against the enhanced-sensitivity Trofile coreceptor tropism assay
    Victoria Sanchez
    Infectious Diseases Unit, Clinical Medicine Department, Universidad Miguel Hernandez, Hospital Universitario de Elche, Elche, Spain
    J Clin Microbiol 48:4135-9. 2010
    ..Results are similar to those obtained with Trofile. The concordance with ES Trofile is better with higher CD4 cell counts and nonexposure to antiretroviral therapy...
  45. doi request reprint Decrease in serial prevalence of coinfection with hepatitis C virus among HIV-infected patients in Spain, 1997-2006
    Santiago Pérez Cachafeiro
    National Epidemiology Centre, Instituto de Salud Carlos III, Madrid, Spain
    Clin Infect Dis 48:1467-70. 2009
    ..8% in 1997 to 19.8% in 2006. This steady decrease in the prevalence of coinfection among Spanish patients was caused by a change in transmission routes of HIV infection...
  46. ncbi request reprint The role of C-reactive protein as a marker for cardiovascular risk associated with antiretroviral therapy in HIV-infected patients
    Mar Masia
    Infectious Diseases Unit, Hospital General Universitario de Elche, Universidad Miguel Hernandez, Elche, Spain
    Atherosclerosis 195:167-71. 2007
    ..019) and current ART (p=0.021). Our results show that C-reactive protein is associated with traditional cardiovascular risk factors, and may then be a marker for cardiovascular risk linked to HIV infection and ART...
  47. pmc Evaluation of endothelial function and subclinical atherosclerosis in association with hepatitis C virus in HIV-infected patients: a cross-sectional study
    Mar Masia
    Infectious Diseases Unit, Hospital General Universitario de Elche, Alicante, Spain
    BMC Infect Dis 11:265. 2011
    ..We evaluated endothelial function and subclinical atherosclerosis in HIV-infected patients with and without HCV...
  48. ncbi request reprint Midregional pro-A-type natriuretic peptide and carboxy-terminal provasopressin may predict prognosis in community-acquired pneumonia
    Mar Masia
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    Clin Chem 53:2193-201. 2007
    ..We aimed to explore the diagnostic accuracy of MR-proANP and CT-proAVP to predict mortality in patients with CAP...
  49. doi request reprint Performance of a population-based HIV-1 tropism phenotypic assay and correlation with V3 genotypic prediction tools in recent HIV-1 seroconverters
    Carmen de Mendoza
    Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain
    J Acquir Immune Defic Syndr 48:241-4. 2008
    ..Pure X4 and X4R5 dual-tropic viruses may be recognized in approximately 15% of drug-naive HIV-1-positive patients. CCR5 antagonists are active against R5 viruses; therefore, HIV tropism should be known before their prescription...
  50. doi request reprint Sensitivity of seven HIV subtyping tools differs among subtypes/recombinants in the Spanish cohort of naïve HIV-infected patients (CoRIS)
    Gonzalo Yebra
    FiBIO IRYCIS Hospital Ramón y Cajal and CIBER ESP, Madrid, Spain
    Antiviral Res 89:19-25. 2011
    ..We evaluated the reliability of subtyping tools vs. phylogeny in a panel of HIV-1 pol sequences from the cohort of naïve patients of the HIV/AIDS Spanish Research Network (CoRIS)...
  51. ncbi request reprint Delayed diagnosis of HIV infection in a multicenter cohort: prevalence, risk factors, response to HAART and impact on mortality
    Paz Sobrino-Vegas
    Red de Investigación en SIDA, Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, Madrid, Spain
    Curr HIV Res 7:224-30. 2009
    ..Although we did not find differences in virological and immunological responses to HAART, we did observe higher mortality in people with DHD. Increased efforts to early diagnose HIV infection are urgently needed...
  52. ncbi request reprint [Tuberculosis in immigrants: clinical and epidemiological differences as compared to the native population (1999-2002)]
    Jose Manuel Ramos
    Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital General Universitario de Elche, Alicante, Spain
    Enferm Infecc Microbiol Clin 22:315-8. 2004
    ..Tuberculosis in immigrants is an emerging disease in industrialized countries...
  53. ncbi request reprint Fulminant hepatitis and fatal toxic epidermal necrolysis (Lyell disease) coincident with clarithromycin administration in an alcoholic patient receiving disulfiram therapy
    Mar Masia
    Infectious Diseases Unit, Department of Internal Medicine, Hospital General Universitario de Elche, Partida Huertos y Molinos s n, 03202 Elche, Alicante, Spain
    Arch Intern Med 162:474-6. 2002
    ..The temporal relationship between drug administration and clinical symptoms in this case suggests a probable interaction between the 2 drugs...
  54. doi request reprint A pilot randomized trial comparing an intensive versus a standard intervention in stable HIV-infected patients with moderate-high cardiovascular risk
    Mar Masia
    Department of Clinical Medicine, Infectious Diseases Unit, Hospital General Universitario de Elche, University Miguel Hernandez, Elche, Alicante, Spain
    J Antimicrob Chemother 64:589-98. 2009
    ..We evaluated the efficacy and safety of an intensive versus a standard intervention in HIV-infected patients with moderate-high cardiovascular risk...
  55. ncbi request reprint [Clinical and epidemiological characteristics of human immunodeficiency virus infection in foreigners residing in Elche, Spain (1998-2003)]
    Jose Manuel Ramos
    Servicio de Medicina Interna, Hospital General Universitario de Elche, Alicante, Spain
    Enferm Infecc Microbiol Clin 23:469-73. 2005
    ..To determine the characteristics of HIV-infection in foreign patients residing in Elche, Spain...
  56. doi request reprint Treatment for hepatitis C virus with pegylated interferon-α plus ribavirin induces anti-atherogenic effects on cardiovascular risk biomarkers in HIV-infected and -uninfected patients
    Mar Masia
    Infectious Diseases Unit, Hospital General Universitario de Elche, Elche, Alicante, Spain
    J Antimicrob Chemother 66:1861-8. 2011
    ....
  57. ncbi request reprint [Prevalence and characteristics of metabolic syndrome among HIV-infected patients from a Mediterranean cohort]
    Enrique Bernal
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Elche, Alicante, Espana
    Med Clin (Barc) 128:172-5; quiz 1 p following 200. 2007
    ..The objective of this study was to estimate the prevalence and characteristics of the metabolic syndrome in patients with HIV infection from a Mediterranean cohort...
  58. ncbi request reprint [Spanish cohort of naïve HIV-infected patients (CoRIS): rationale, organization and initial results]
    Ana María Caro-Murillo
    Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, Madrid, Spain
    Enferm Infecc Microbiol Clin 25:23-31. 2007
    ..To describe the methodology and baseline results of the Spanish cohort of naïve HIV-infected patients included in the Research Network on HIV/AIDS (CoRIS)...
  59. ncbi request reprint Prevalence of X4 tropic viruses in patients recently infected with HIV-1 and lack of association with transmission of drug resistance
    Carmen de Mendoza
    Infectious Diseases Department, Hospital Carlos III, Madrid, Spain
    J Antimicrob Chemother 59:698-704. 2007
    ..HIV-1 co-receptor usage may play a critical role in AIDS pathogenesis. Information on viral tropism in HIV-1 seroconverters is scarce, as is the relationship with transmission of drug-resistant viruses...
  60. doi request reprint Chagas disease in Latin American pregnant immigrants: experience in a non-endemic country
    Jose M Ramos
    Infectious Diseases Unit, Hospital General Universitario de Elche, Elche, Spain
    Arch Gynecol Obstet 285:919-23. 2012
    ..Migration of women of childbearing age from Latin America to developed countries may spread the disease to non-endemic areas through vertical transmission...
  61. ncbi request reprint [Usefulness of acute-phase proteins in community-acquired pneumonia]
    Carlos Mirete
    Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital General Universitario de Elche, Elche, Alicante, Spain
    Med Clin (Barc) 122:245-7. 2004
    ..We aimed to study the usefulness of acute-phase proteins in the evolution and microbial diagnosis of community-acquired pneumonia (CAP)...
  62. doi request reprint [Imported and non-imported diseases in the immigrant population. A decade of experience from an infectious diseases unit]
    Jose Manuel Ramos
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Alicante, Espana
    Enferm Infecc Microbiol Clin 29:185-92. 2011
    ..Immigration is an inexorable process. Immigrants may suffer infectious diseases commonly seen in our environment, or those more exotic or more prevalent in their own environment...
  63. pmc Predictors of pneumococcal co-infection for patients with pandemic (H1N1) 2009
    Mar Masia
    Hospital Universitario de Elche, Elche, Spain
    Emerg Infect Dis 17:1475-8. 2011
    ..We found 14% prevalence, with one third of patients having nonpneumonic infections. A severity assessment score >1 and high C-reactive protein levels were predictors of pneumococcal co-infection...
  64. ncbi request reprint Usefulness of procalcitonin levels in community-acquired pneumonia according to the patients outcome research team pneumonia severity index
    Mar Masia
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Camí de la Almazara S N 03203 ELCHE, Alicante, Spain
    Chest 128:2223-9. 2005
    ..To evaluate the usefulness of procalcitonin serum levels as a predictor of etiology and prognosis in adult patients with community-acquired pneumonia (CAP) when they are stratified according to severity...
  65. ncbi request reprint Fatal infection due to larval cysts of cestodes (neurocysticercosis and hydatid disease) in human immunodeficiency virus (HIV) infected patients in Spain: report of two cases
    Jose M Ramos
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    Scand J Infect Dis 39:719-23. 2007
    ..Both patients died. Although infrequent, infections by larval cestodes constitute a cause of disease in HIV-infected patients in developed countries, and might be linked with a more severe presentation...
  66. doi request reprint [Spanish scientific research output on tuberculosis indexed in MEDLINE, 1997-2006]
    Jose Manuel Ramos
    Unidad de Enfermedades Infecciosas, Hospital General Universitario de Elche, Alicante, Espana
    Arch Bronconeumol 45:271-8. 2009
    ..To analyze Spanish scientific research output related to tuberculosis during the 10-year period from 1997 through 2006 and to consider it within the context of European Union (EU) productivity...
  67. doi request reprint [HIV infection in different age groups: Potential implications for prevention. CoRIS Cohort, Spain, 2004-2008]
    Ana María Caro-Murillo
    Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, CIBERESP, Madrid, Espana
    Med Clin (Barc) 134:521-7. 2010
    ..To describe the characteristics of HIV infected adults according to their age at recruitment in CoRIS...
  68. doi request reprint Seroprevalence of Toxoplasma gondii infection among immigrant and native pregnant women in Eastern Spain
    Jose M Ramos
    Infectious Diseases Unit, Hospital General Universitario de Elche, Cami de l Amàssera, 11, 03203, Elche, Alicante, Spain
    Parasitol Res 109:1447-52. 2011
    ..However, no cases were found in Asian immigrants, highlighting the importance of primary prevention of this infection in pregnant women coming from that geographic region...
  69. doi request reprint Prevalence and impact of body physical changes in HIV patients treated with highly active antiretroviral therapy: results from a study on patient and physician perceptions
    Esther Cabrero
    Medical Department, Abbott Laboratories, Avenida de Burgos 91, Madrid, Spain
    AIDS Patient Care STDS 24:5-13. 2010
    ..Physicians should be aware of the psychosocial consequences of BPC in HIV patients in order to improve patient well-being...
  70. ncbi request reprint Improving outcomes of elderly patients with community-acquired pneumonia
    Felix Gutierrez
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Universidad Miguel Hernandez, Elche, Spain
    Drugs Aging 25:585-610. 2008
    ..Assessment of functional clinical outcome variables, in addition to survival, is strongly recommended for this population...
  71. pmc Pharmacokinetics of fosamprenavir plus ritonavir in human immunodeficiency virus type 1-infected adult subjects with hepatic impairment
    Maria J Perez-Elias
    Hospital Ramon y Cajal, Madrid, Spain
    Antimicrob Agents Chemother 53:5185-96. 2009
    ..No significant safety issues were identified; however, plasma amprenavir and ritonavir exposures were more variable in subjects with hepatic impairment, and those patients should be closely monitored for safety and virologic response...
  72. doi request reprint Relationship between ankle-brachial index and carotid intima-media thickness in HIV-infected patients
    Felix Gutierrez
    Infectious Diseases Unit, Hospital General Universitario de Elche, Alicante, Spain
    AIDS 22:1369-71. 2008
    ..Ankle-brachial index was associated with carotid intima-media thickness. Patients with low ankle-brachial index, but not those with high ankle-brachial index, had high carotid intima-media thickness...
  73. doi request reprint Seroprevalence of HTLV infection among immigrant pregnant women in the Mediterranean coast of Spain
    Jose M Ramos
    Infectious Diseases Unit, Hospital General Universitario de Elche, Alicante, Spain
    J Clin Virol 51:192-4. 2011
    ..Universal HTLV antenatal screening is currently not mandatory in European countries. However, the large number of immigrants coming from HTLV-I endemic areas might force to change this recommendation in the near future...
  74. ncbi request reprint Disorders of body fat distribution in HIV-1-infected patients
    Santiago Moreno
    Hospital Ramon y Cajal, Madrid, Spain
    AIDS Rev 11:126-34. 2009
    ..Neither the interruption of antiretroviral therapy nor the use of metformin, glitazones or growth hormone analogs can be recommended due to their limited efficacy or associated complications...
  75. doi request reprint Etravirine resistance associated mutations in HIV-infected patients failing efavirenz or nevirapine in the Spanish antiretroviral resistance database
    Eva Poveda
    Hospital Carlos III, Madrid, Spain
    AIDS 24:469-71. 2010
    ..Thus, more than 80% patients with prior failure to nonnucleoside reverse transcriptase inhibitors could potentially benefit from etravirine rescue therapy...
  76. doi request reprint Microbiology and outcome of iliopsoas abscess in 124 patients
    Vicente Navarro López
    Infectious Diseases Unit, Internal Medicine Department, Hospital de Torrevieja, Alicante, Spain
    Medicine (Baltimore) 88:120-30. 2009
    ..Among those with secondary IPA, most abscesses are secondary to a skeletal source. A bacterial etiology can be identified in most cases. The overall prognosis of patients with this condition is good...
  77. doi request reprint Mycobacterium marinum infection complicated by anti-tumour necrosis factor therapy
    Jose M Ramos
    Infectious Diseases Unit, Internal Medicine Department, Hospital General Universitario de Elche, Alicante, Spain
    J Med Microbiol 59:617-21. 2010
    ..After starting ethambutol and rifampicin and discontinuing infliximab, a worsening appeared. M. marinum infection may have a potential local spread and systemic dissemination in patients treated with TNF-alpha inhibitors...
  78. doi request reprint [Prenatal screening for Trypanosoma cruzi and human T lymphotropic virus types 1 and 2 in pregnant Latin American women]
    Jose Manuel Ramos
    Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital General Universitario de Elche, Alicante, Espana
    Enferm Infecc Microbiol Clin 27:165-7. 2009
    ..To estimate the seroprevalence of infection by Trypanosoma cruzi and human T lymphotropic virus (HTLV) in pregnant Latin American women...
  79. ncbi request reprint Single-slice computed tomography and anthropometric skinfold analysis for evaluation of facial lipoatrophy in HIV-infected patients
    Sergio Padilla
    Infectious Diseases Unit, Department of Internal Medicine, Hospital General Universitario de Elche, Alicante, Spain
    Clin Infect Dis 39:1848-51. 2004
    ..CT may be a useful technique to diagnose and monitor facial lipoatrophy...
  80. doi request reprint First case of post-endoscopic retrograde cholangiopancreatography bacteraemia caused by Acinetobacter ursingii in a patient with choledocholithiasis and cholangitis
    Victoria Ortiz de la Tabla Ducasse
    Microbiology Service, Hospital Universitario San Juan de Alicante, Spain
    J Med Microbiol 57:1170-1. 2008
    ..ursingii bacteraemia. This report highlights the inadequacies of conventional phenotypic tests usually available in clinical microbiology laboratories for the identification of Acinetobacter species...
  81. ncbi request reprint [Scientific production in microbiology and affinity areas in Spain during 1990-2002]
    Jose Manuel Ramos
    Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital General Universitario de Elche, Alicante, Spain
    Enferm Infecc Microbiol Clin 23:406-14. 2005
    ..To analyze the production and repercussions of the scientific activity of Spanish authors in the fields of microbiology, mycology, parasitology and virology...
  82. ncbi request reprint Characteristics and outcome of AIDS-related Hodgkin lymphoma before and after the introduction of highly active antiretroviral therapy
    Juan Berenguer
    Hospital Gregorio Maranon, Madrid, Spain
    J Acquir Immune Defic Syndr 47:422-8. 2008
    ..We analyzed survival, therapeutic response, and prognostic factors in patients with HIV-related Hodgkin lymphoma (HL) treated or not with highly active antiretroviral therapy (HAART)...
  83. doi request reprint Seroprevalence of HIV-1, HBV, HTLV-1 and Treponema pallidum among pregnant women in a rural hospital in Southern Ethiopia
    Jose M Ramos
    Infectious Diseases Unit, Hospital General Universitario de Elche, Alicante, Spain Gambo General Rural Hospital, Shashamane, Ethiopia
    J Clin Virol 51:83-5. 2011
    ..pallidum infections are highly prevalent. However, information on seroprevalence of these infections among antenatal care attendees is very scarce and the majority of studies have been conducted in pregnant women from urban areas...
  84. pmc Clinical case of endocarditis due to Trichosporon inkin and antifungal susceptibility profile of the organism
    Jose M Ramos
    Unidad de Enfermedades Infecciosas, Servicio de Medicina, Hospital General Universitario de Elche, Alicante, Spain
    J Clin Microbiol 42:2341-4. 2004
    ..Voriconazole and amphotericin B had the most potent activities in vitro against the isolates, with MIC geometric means of 0.11 and 0.30 microg/ml, respectively...
  85. doi request reprint Diagnostic accuracy of sTREM-1 to identify infection in critically ill patients with systemic inflammatory response syndrome
    Jaime Latour-Pérez
    Hospital General Universitario de Elche, Servicio de Medicina Intensiva, Camí Vell de l Almàssera 11, 03203 Elche, Spain
    Clin Biochem 43:720-4. 2010
    ..To assess the accuracy of plasma levels of soluble Triggering Receptor Expressed on Myeloid cells (sTREM)-1 to diagnose infection in critical patients with systemic inflammatory response syndrome (SIRS)...