Cristina Gravalos

Summary

Country: Spain

Publications

  1. doi request reprint HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target
    C Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain
    Ann Oncol 19:1523-9. 2008
  2. pmc A randomized phase II study to compare oxaliplatin plus 5-fluorouracil and leucovorin (FOLFOX4) versus oxaliplatin plus raltitrexed (TOMOX) as first-line chemotherapy for advanced colorectal cancer
    Cristina Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain
    Clin Transl Oncol 14:606-12. 2012
  3. ncbi request reprint Functions and workload of medical oncologists in Spain
    Cristina Gravalos
    Servicio de Oncologia Medica, Hospital Universitario 12 de Octubre, Avda De Córdoba, s n km 5, 400, ES 28041 Madrid, Spain
    Clin Transl Oncol 14:423-9. 2012
  4. ncbi request reprint Adjuvant chemotherapy for stages II, III and IV of colon cancer
    Cristina Gravalos
    Medical Oncology Service, University Hospital 12 de Octubre, Madrid, Spain
    Clin Transl Oncol 11:526-33. 2009
  5. ncbi request reprint SEOM clinical guidelines for the adjuvant treatment of colorectal cancer
    Cristina Grávalos Castro
    Medical Oncology Department, 12 de Octubre University Hospital, Madrid, Spain
    Clin Transl Oncol 12:724-8. 2010
  6. doi request reprint Integration of panitumumab into the treatment of colorectal cancer
    Cristina Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Avda de Andalucía s n Km 5 400, Madrid, Spain
    Crit Rev Oncol Hematol 74:16-26. 2010
  7. doi request reprint Surgical resection of a solitary pancreatic metastasis from colorectal cancer: a new step to a cure?
    Cristina Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain
    Clin Colorectal Cancer 7:398-401. 2008
  8. ncbi request reprint Role of tyrosine kinase inhibitors in the treatment of advanced colorectal cancer
    Cristina Gravalos
    Medical Oncology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
    Clin Colorectal Cancer 6:691-9. 2007
  9. doi request reprint Phase II study of trastuzumab and cisplatin as first-line therapy in patients with HER2-positive advanced gastric or gastroesophageal junction cancer
    Cristina Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain
    Clin Transl Oncol 13:179-84. 2011
  10. doi request reprint The potential role of sunitinib in gastrointestinal cancers other than GIST
    Cristina Gravalos
    Medical Oncology Department, 12 de Octubre Universitary Hospital, Avda de Andalucía s n Km 5 400, 28041 Madrid, Spain
    Crit Rev Oncol Hematol 76:36-43. 2010

Collaborators

Detail Information

Publications19

  1. doi request reprint HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target
    C Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain
    Ann Oncol 19:1523-9. 2008
    ..This review summarizes the rationale, preclinical evidence, retrospective clinical analyses, and the interim clinical data pertaining HER2 therapies in gastric cancer...
  2. pmc A randomized phase II study to compare oxaliplatin plus 5-fluorouracil and leucovorin (FOLFOX4) versus oxaliplatin plus raltitrexed (TOMOX) as first-line chemotherapy for advanced colorectal cancer
    Cristina Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain
    Clin Transl Oncol 14:606-12. 2012
    ..The aim of this study was to compare TOMOX versus FOLFOX4 as first-line treatment of advanced colorectal cancer (CRC)...
  3. ncbi request reprint Functions and workload of medical oncologists in Spain
    Cristina Gravalos
    Servicio de Oncologia Medica, Hospital Universitario 12 de Octubre, Avda De Córdoba, s n km 5, 400, ES 28041 Madrid, Spain
    Clin Transl Oncol 14:423-9. 2012
    ..Finally, the ratio recommended by SEOM is one medical oncologist for every 83 new patients a year...
  4. ncbi request reprint Adjuvant chemotherapy for stages II, III and IV of colon cancer
    Cristina Gravalos
    Medical Oncology Service, University Hospital 12 de Octubre, Madrid, Spain
    Clin Transl Oncol 11:526-33. 2009
    ..This article reviews the state of the art and the future perspectives of adjuvant therapy in colon cancer. Prognostic and predictive factors are also commented on...
  5. ncbi request reprint SEOM clinical guidelines for the adjuvant treatment of colorectal cancer
    Cristina Grávalos Castro
    Medical Oncology Department, 12 de Octubre University Hospital, Madrid, Spain
    Clin Transl Oncol 12:724-8. 2010
    ..In this manuscript, the clinical guidelines of the Spanish Society of Medical Oncology (SEOM) for diagnosis and adjuvant treatment of colon cancer and rectal cancer are reported...
  6. doi request reprint Integration of panitumumab into the treatment of colorectal cancer
    Cristina Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Avda de Andalucía s n Km 5 400, Madrid, Spain
    Crit Rev Oncol Hematol 74:16-26. 2010
    ..This article reviews the preclinical and pharmacokinetics data, activity and tolerance of panitumumab in mCRC patients. Potential predictive factors of response are also discussed...
  7. doi request reprint Surgical resection of a solitary pancreatic metastasis from colorectal cancer: a new step to a cure?
    Cristina Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain
    Clin Colorectal Cancer 7:398-401. 2008
    ..Additional chemotherapy is recommended...
  8. ncbi request reprint Role of tyrosine kinase inhibitors in the treatment of advanced colorectal cancer
    Cristina Gravalos
    Medical Oncology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
    Clin Colorectal Cancer 6:691-9. 2007
    ..Efficacy of the oral multitargeted TKIs sorafenib and sunitinib is under investigation. This article aims to review the role of TKIs in advanced CRC...
  9. doi request reprint Phase II study of trastuzumab and cisplatin as first-line therapy in patients with HER2-positive advanced gastric or gastroesophageal junction cancer
    Cristina Gravalos
    Medical Oncology Department, University Hospital 12 de Octubre, Madrid, Spain
    Clin Transl Oncol 13:179-84. 2011
    ..We conducted a multicentre phase II trial to evaluate trastuzumab in combination with cisplatin in patients with untreated HER2-positive advanced gastric or GEJ cancer...
  10. doi request reprint The potential role of sunitinib in gastrointestinal cancers other than GIST
    Cristina Gravalos
    Medical Oncology Department, 12 de Octubre Universitary Hospital, Avda de Andalucía s n Km 5 400, 28041 Madrid, Spain
    Crit Rev Oncol Hematol 76:36-43. 2010
    ....
  11. doi request reprint Pilot study on workload estimate in breast cancer, lung cancer and colorectal cancer in a Medical Oncology Service at Valme hospital
    Javier Salvador
    Servicio de Oncologia Medica, Avda Cádiz s nº, 41014, Sevilla, Spain
    Clin Transl Oncol 14:820-6. 2012
    ..Finally, the time spent on each visit or day of hospitalisation was that recommended by the SEOM, achieving an ultimate ratio of 1 oncologist for every 83 first visits...
  12. pmc First-line cetuximab plus capecitabine in elderly patients with advanced colorectal cancer: clinical outcome and subgroup analysis according to KRAS status from a Spanish TTD Group Study
    Javier Sastre
    Medical Oncology Department, Hospital Clinico San Carlos, Calle Martín Lagos s n 28040 Madrid, Spain
    Oncologist 17:339-45. 2012
    ..Single-agent cetuximab is safe and active in elderly patients with advanced colorectal cancer (CRC). A cetuximab-capecitabine combination has not previously been tested in elderly patients with advanced CRC...
  13. doi request reprint SEOM clinical guidelines for the diagnosis and treatment of gastric adenocarcinoma
    Fernando Rivera
    Servicio de Oncologia Medica, Hospital Universitario Marques de Valdecilla, Santander, Spain
    Clin Transl Oncol 14:528-35. 2012
    ..Finally, an outline is provided of the main lines of research and development of therapies for this disease...
  14. ncbi request reprint Recommendations on current approach to gastric cancer
    Fernando Rivera
    Medical Oncology Department, Marques de Valdecilla University Hospital, Santander, Spain
    Clin Transl Oncol 11:518-25. 2009
    ..It would be desirable to incorporate biomarker studies in these trials in order to identify the best treatment for each patient...
  15. ncbi request reprint Phase II study of trabectedin in pretreated patients with advanced colorectal cancer
    Luis Paz-Ares
    Medical Oncology Deparment, Hospital Universitario 12 de Octubre, Madrid, Spain
    Clin Colorectal Cancer 6:522-8. 2007
    ..This open-label, nonrandomized, phase II study was aimed at evaluating the efficacy and toxicity of trabectedin over a 3-hour intravenous infusion every 3 weeks in patients with pretreated advanced colorectal cancer...
  16. ncbi request reprint A phase I, dose-finding study of irinotecan (CPT-11) short i.v. infusion combined with fixed dose of 5-fluorouracil (5-FU) protracted i.v. infusion in adult patients with advanced solid tumours
    Javier Sastre
    Servicio de Oncologia Medica, Hospital Clinico San Carlos de Madrid, Madrid, Spain
    Cancer Chemother Pharmacol 55:453-60. 2005
    ..5-FU. This phase I pharmacokinetic and clinical study evaluated escalating CPT-11 doses administered every 3 weeks combined with a fixed dose of 5-FU CI over 14 days to find the maximum tolerated dose (MTD) of this combined chemotherapy...
  17. ncbi request reprint Irinotecan (CPT-11)-based chemotherapy as induction treatment for advanced colorectal cancer
    Miguel Quintela-Fandino
    Hospital 12 de Octubre, Madrid, Spain
    Anticancer Drugs 16:31-8. 2005
    ..Both toxicity profile and postoperative complications were acceptable. Nevertheless, the definitive role of irinotecan as induction treatment should be confirmed in future clinical trials...
  18. ncbi request reprint [Woman with a history of cancer and pain in the right thigh: an infection spread by contiguity]
    Francisco López-Medrano
    Unidad de Enfermedades Infecciosas, Hospital Universitario 12 de Octubre, Madrid, Espana
    Enferm Infecc Microbiol Clin 24:129-30. 2006
  19. pmc Approach to early-onset colorectal cancer: clinicopathological, familial, molecular and immunohistochemical characteristics
    Jose Perea
    Department of Surgery, Hospital Universitario 12 de Octubre, Avda de Cordoba s n, Madrid, Spain
    World J Gastroenterol 16:3697-703. 2010
    ..To characterize clinicopathological and familial features of early-onset colorectal cancer (CRC) and compare features of tumors with and without microsatellite instability (MSI)...