F Grases

Summary

Country: Spain

Publications

  1. ncbi request reprint Absorption and excretion of orally administered inositol hexaphosphate (IP(6) or phytate) in humans
    F Grases
    Laboratory of Renal Lithiasis Research, Faculty of Science, University of Illes Balears, 07071 Palma de Mallorca, Spain
    Biofactors 15:53-61. 2001
  2. ncbi request reprint Inositol hexakisphosphate in urine: the relationship between oral intake and urinary excretion
    F Grases
    Laboratory of Renal Lithiasis Research, University of the Belearic Islands, Palma de Mallorca, Spain
    BJU Int 85:138-42. 2000
  3. pmc Factors affecting calcium oxalate dihydrate fragmented calculi regrowth
    A Costa-Bauza
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma of Mallorca, Spain
    BMC Urol 6:16. 2006
  4. ncbi request reprint Phytate levels in diverse rat tissues: influence of dietary phytate
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    Br J Nutr 86:225-31. 2001
  5. ncbi request reprint Phytate prevents tissue calcifications in female rats
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    Biofactors 11:171-7. 2000
  6. doi request reprint Urinary pH and renal lithiasis
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma de Mallorca, Spain
    Urol Res 40:41-6. 2012
  7. ncbi request reprint Influence of concomitant food intake on the excretion of orally administered myo-inositol hexaphosphate in humans
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institut of Health Sciences Research, University of Balearic Islands, Palma of Mallorca, Spain
    J Med Food 9:72-6. 2006
  8. ncbi request reprint Dietary phytate and mineral bioavailability
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    J Trace Elem Med Biol 15:221-8. 2001
  9. doi request reprint Anticalculus effect of a triclosan mouthwash containing phytate: a double-blind, randomized, three-period crossover trial
    F Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research, University of Balearic Islands, Palma de Mallorca, Spain
    J Periodontal Res 44:616-21. 2009
  10. ncbi request reprint Urinary phytate in calcium oxalate stone formers and healthy people--dietary effects on phytate excretion
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    Scand J Urol Nephrol 34:162-4. 2000

Collaborators

  • J G March
  • Z Wang
  • Antonia Costa-Bauza
  • Rafael M Prieto
  • Takahiro Yasui
  • A A López-González
  • G Grases
  • S Vaidyanathan
  • B M Simonet
  • P Roca
  • M T Vicente-Herrero
  • B Mari
  • J Perello
  • J A Pérez-Castelló
  • E Rigo
  • B Isern
  • P Sanchis
  • A Casero
  • B M Soni
  • K Tozawa
  • B Schurch
  • K Kohri
  • P Sett
  • I D Watson
  • O Jonsson
  • A Z Buczynski
  • W D Fraser
  • J J Wyndaele
  • G Singh
  • I P Heilberg
  • P L Hughes

Detail Information

Publications31

  1. ncbi request reprint Absorption and excretion of orally administered inositol hexaphosphate (IP(6) or phytate) in humans
    F Grases
    Laboratory of Renal Lithiasis Research, Faculty of Science, University of Illes Balears, 07071 Palma de Mallorca, Spain
    Biofactors 15:53-61. 2001
    ..Thus, the normal plasma and urinary concentrations, can be obtained either by consumption of a IP(6)ND taking a long time or in a short period by IP(6) supplements...
  2. ncbi request reprint Inositol hexakisphosphate in urine: the relationship between oral intake and urinary excretion
    F Grases
    Laboratory of Renal Lithiasis Research, University of the Belearic Islands, Palma de Mallorca, Spain
    BJU Int 85:138-42. 2000
    ..To study the relationship between the oral intake of inositol hexakisphosphate (InsP6, phytic acid, an inhibitor of urinary crystallization) and its urinary excretion, to establish their possible mutual influence...
  3. pmc Factors affecting calcium oxalate dihydrate fragmented calculi regrowth
    A Costa-Bauza
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma of Mallorca, Spain
    BMC Urol 6:16. 2006
    ..This study examined the effect of various urinary conditions and crystallization inhibitors on the regrowth of spontaneously-passed post-ESWL COD calculi fragments...
  4. ncbi request reprint Phytate levels in diverse rat tissues: influence of dietary phytate
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    Br J Nutr 86:225-31. 2001
    ..Consequently, considering that InsP6 could be involved in some important biological roles, the value of any diet on supplying this substance is noteworthy...
  5. ncbi request reprint Phytate prevents tissue calcifications in female rats
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    Biofactors 11:171-7. 2000
    ..Only rats of the AIN-76 A group displayed mineral deposits at the corticomedullary junction. These findings demonstrated that the absence of phytate in the AIN-76 A diet is one of the causes of renal calcification in female rats...
  6. doi request reprint Urinary pH and renal lithiasis
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma de Mallorca, Spain
    Urol Res 40:41-6. 2012
    ..5 and 6.0 because the injured papilla acts as a heterogeneous nucleant. Consequently, measurement of urinary pH may be used to evaluate the lithogen risk of given urine...
  7. ncbi request reprint Influence of concomitant food intake on the excretion of orally administered myo-inositol hexaphosphate in humans
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institut of Health Sciences Research, University of Balearic Islands, Palma of Mallorca, Spain
    J Med Food 9:72-6. 2006
    ..Thus, if InsP6 supplements of vegetal origin are consumed to maintain the optimum InsP6 levels needed for a healthy status, these supplements can be consumed either during or between meals with the same efficacy...
  8. ncbi request reprint Dietary phytate and mineral bioavailability
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    J Trace Elem Med Biol 15:221-8. 2001
    ....
  9. doi request reprint Anticalculus effect of a triclosan mouthwash containing phytate: a double-blind, randomized, three-period crossover trial
    F Grases
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research, University of Balearic Islands, Palma de Mallorca, Spain
    J Periodontal Res 44:616-21. 2009
    ..The aim of the present study was to examine the effects of phytate and zinc, administered in a mouthwash solution, to prevent the formation of dental calculus...
  10. ncbi request reprint Urinary phytate in calcium oxalate stone formers and healthy people--dietary effects on phytate excretion
    F Grases
    Laboratory of Renal Lithiasis Research, University of Balearic Islands, Palma de Mallorca, Spain
    Scand J Urol Nephrol 34:162-4. 2000
    ..This demonstrated the importance of dietary phytate in maintaining adequate urinary levels to permit effective crystallization inhibition of calcium salts and consequently preventing renal stone development...
  11. ncbi request reprint Effects of phytate and pyrophosphate on brushite and hydroxyapatite crystallization. Comparison with the action of other polyphosphates
    F Grases
    Laboratory of Urolithiasis Research, Faculty of Sciences, University of Illes Balears, Palma de Mallorca, Spain
    Urol Res 28:136-40. 2000
    ..87x10(-6) M prevented crystallization during time periods of at least 1 h). This demonstrates that low excretion of these substances would pose a risk of renal lithiasis...
  12. ncbi request reprint Uric acid urolithiasis and crystallization inhibitors
    F Grases
    Laboratory of Urolithiasis Research, Faculty of Sciences, University of Illes Balears, Palma de Mallorca, Spain
    Urol Int 62:201-4. 1999
    ..From the results obtained it can be deduced that mainly glycoproteins, glycosaminoglycans and surfactant substances can exert protective effects against uric acid crystallization...
  13. ncbi request reprint Absorption of myo-inositol hexakisphosphate (InsP6) through the skin in humans
    F Grases
    Laboratory of Renal Lithiasis Research, Institute of Health Sciences Research, Faculty of Sciences, University of Balearic Islands, 07122 Palma de Mallorca, Spain
    Pharmazie 61:652. 2006
    ..These results demonstrate the topical application as a suitable administration route of InsP6 in humans...
  14. ncbi request reprint Effect of phytate on element bioavailability in the second generation of rats
    F Grases
    Laboratorio de Investigación en Litiasis Renal, Facultad de Ciencias, Universitat de les Illes Balears, Palma de Mallorca, Spain
    J Trace Elem Med Biol 17:229-34. 2004
    ..However, using this purified diet, the zinc concentration in bone resulted around 10 times higher than found in rats fed with a common non purified rat chow...
  15. ncbi request reprint Dietary myo-inositol hexaphosphate prevents dystrophic calcifications in soft tissues: a pilot study in Wistar rats
    F Grases
    Laboratory of Renal Lithiasis Research, Institute of Health Sciences IUNICS, University of Balearic Islands, Ctra Valldemossa km 7 5, 07071, Palma de Mallorca, Spain
    Life Sci 75:11-9. 2004
    ..3-0.4 microM) clearly inhibited the development of dystrophic calcifications in soft tissues. These results demonstrates that myo-inositol hexaphosphate acts as an inhibitor of calcium salt crystallization...
  16. ncbi request reprint Study on concretions developed around urinary catheters and mechanisms of renal calculi development
    F Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University Illes Balears, Palma de Mallorca, Spain
    Nephron 88:320-8. 2001
    ..To study the structure and composition of encrustation and concretions developed on urinary catheters to better understand their formation mechanism to be able to prevent them...
  17. ncbi request reprint Determination of phosphate in urine by sequential injection analysis
    B M Simonet
    Department of Chemistry, University of Balearic Islands, 07071 Palma de Mallorca, Spain
    Fresenius J Anal Chem 369:96-102. 2001
    ..This interference was solved using a cation exchange resin as a part of the manifold. Considering the low toxicity of used reagents, these methods can be considered as a contribution to Green Analytical Chemistry...
  18. ncbi request reprint An experimental study on residual lithiasis after shock wave lithotripsy
    A Costa-Bauza
    Laboratory of Renal Lithiasis Research, Institute of Health Sciences Research IUNICS, University of Balearic Islands 07122 Palma of Mallorca, Spain
    Urol Res 33:51-6. 2005
    ..The in vitro regrowth of post-ESWL COM fragments was clearly influenced by the presence of crystallization inhibitors. These data also demonstrate the importance that effective prophylactic therapies could exert on preventing recurrence...
  19. ncbi request reprint Study of potassium phytate effects on decreasing urinary calcium in rats
    F Grases
    Laboratorio de Investigación en Litiasis Renal, University of Balearic Islands, Palma de Mallorca, Spain
    Urol Int 72:237-43. 2004
    ....
  20. ncbi request reprint Kinetic versus thermodynamic factors in calcium renal lithiasis
    F Grases
    Laboratory of Renal Lithiasis Research, University of Illes Balears, Palma de Mallorca, Spain
    Int Urol Nephrol 32:19-27. 2000
    ..The results of this evaluation were used to assess the possible effectiveness of a given pharmacological treatment...
  21. doi request reprint Effects of Mediterranean diets with low and high proportions of phytate-rich foods on the urinary phytate excretion
    Rafael M Prieto
    Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma, Spain
    Eur J Nutr 49:321-6. 2010
    ..This includes the prevention of pathological calcifications such as renal calculi, dental calculi and cardiovascular calcification, due its action as crystallization inhibitor of calcium salts, and as preventive of cancer...
  22. ncbi request reprint Intracellular and extracellular myo-inositol hexakisphosphate (InsP6), from rats to humans
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute of Health Sciences Research, University of Balearic Islands, E 07122 Palma of Mallorca, Spain
    Anticancer Res 25:2593-7. 2005
    ..From these results, it can be deduced that health benefits linked to extracellular InsP6 must be related to dietary InsP6...
  23. ncbi request reprint Uric acid calculi: types, etiology and mechanisms of formation
    F Grases
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University of Illes Balears, Ctra Valldemossa km 7 5, 07071, Palma de Mallorca, Spain
    Clin Chim Acta 302:89-104. 2000
    ....
  24. doi request reprint A simple and rapid colorimetric method for determination of phytate in urine
    Antonia Costa-Bauza
    Laboratory of Renal Lithiasis Research, Faculty of Sciences, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, Ctra de Valldemossa, km 7 5, 07122, Palma de Mallorca, Spain
    Urol Res 40:663-9. 2012
    ..The assay can be run in most analytical laboratories and does not require sophisticated instrumentation...
  25. ncbi request reprint Determination of phytic acid by gas chromatography-mass spectroscopy: application to biological samples
    J G March
    Department of Chemistry, University of Balearic Islands, Palma de Mallorca, Spain
    J Chromatogr B Biomed Sci Appl 757:247-55. 2001
    ..Phytic acid amounts found in rat organs ranged from 1.07 g kg(-1) for bone to 32.0 g kg(-1) for brain. Phytic acid in human plasma was of the order of 0.14 mg l(-1). In kidney stones, phytic acid was found in calcium containing stones...
  26. ncbi request reprint Phytate (myo-inositol hexaphosphate) and risk factors for osteoporosis
    A A López-González
    Servicio de Prevencion de Riesgos Laborales, Gestion Sanitaria de Mallorca, Palma de Mallorca, Spain
    J Med Food 11:747-52. 2008
    ..Phytate consumption had a protective effect against osteoporosis, suggesting that low phytate consumption should be considered an osteoporosis risk factor...
  27. ncbi request reprint Structural features of three ureterocele calculi
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute for Health Sciences Research, Ed Mateu Orfila Rotger, University of Balearic Islands, Ctra Valldemossa km 7 5, 07122, Palma de Mallorca, Spain
    Int Urol Nephrol 39:765-9. 2007
    ....
  28. doi request reprint Melamine urinary bladder stone
    F Grases
    Laboratory of Renal Lithiasis Research, Universitary Institute of Health Science Research, University of Balearic Islands, Palma de Mallorca, Spain
    Urology 73:1262-3. 2009
    ..We report a unique case of a melamine bladder urinary stone. A physiopathologic mechanism of formation is proposed and discussed...
  29. ncbi request reprint Study of a myo-inositol hexaphosphate-based cream to prevent dystrophic calcinosis cutis
    F Grases
    Laboratory of Renal Lithiasis Research and Biomineralization, University Institute of Health Sciences Research IUNICS, University of Balearic Islands, 07122 Palma de Mallorca, Spain
    Br J Dermatol 152:1022-5. 2005
    ..Myo-inositol hexaphosphate (InsP(6)) is a diet-dependent molecule found in all mammalian fluids and tissues, which exhibits an extraordinary capacity as a crystallization inhibitor of calcium salts...
  30. ncbi request reprint Recurrent vesical calculi, hypercalciuria, and biochemical evidence of increased bone resorption in an adult male with paraplegia due to spinal cord injury: is there a role for intermittent oral disodium etidronate therapy for prevention of calcium phosph
    S Vaidyanathan
    Regional Spinal Injuries Centre, District General Hospital, Southport, UK
    Spinal Cord 43:269-77. 2005
    ..Clinical case report with comments by colleagues from Sweden, Poland, Spain, Brazil, Japan, Belgium and Switzerland...
  31. ncbi request reprint Anxiety and stress among science students. Study of calcium and magnesium alterations
    G Grases
    University of Balearic Islands, Dept Applied Pedagogy and Educational Psychology, Palma of Mallorca, Spain
    Magnes Res 19:102-6. 2006
    ..Nevertheless, stress also correlates with a urinary calcium increase which was not detected in the present study...