Research Topics
| Francisco GrandasSummaryCountry: Spain Publications
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Detail Information
Publications
Nocturnal problems occurring in Parkinson's diseaseF Grandas
Department of Neurology, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo 46, 28007 Madrid, Spain
Neurology 63:S8-11. 2004..This article reviews the clinical characteristics of some nocturnal motor problems that often induce sleep disruption in PD patients...
Treatment of Parkinson's disease in SpainFrancisco Grandas
Servicio de Neurologia, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Mov Disord 18:87-9. 2003....
Transient blepharospasm secondary to unilateral striatal infarctionFrancisco Grandas
Service of Neurology, Hospital General Universitario Gregorio Maranon, C Doctor Esquerdo, 46, 28007 Madrid, Spain
Mov Disord 19:1100-2. 2004..This case emphasizes the role of the nondominant striatum in the pathophysiology of eyelid motor abnormalities...
Long-term effectiveness and quality of life improvement in entacapone-treated Parkinson's disease patients: the effects of an early therapeutic interventionF Grandas
Department of Neurology, Hospital Universitario Gregorio Maranon, Madrid, Spain
Eur J Neurol 14:282-9. 2007..An early adjustment of entacapone and levodopa doses reduces the number of treatment discontinuations during the first months of treatment...
HemiballismusFrancisco Grandas
Department of Neurology, Hospital Universitario Gregorio Marañón and Parkinson s Disease and Movement Disorders Unit, Hospital Beata Maria Ana, Madrid, Spain
Handb Clin Neurol 100:249-60. 2011..Surgical treatment, especially pallidotomy, is a therapeutic option for the minority of patients with severe persistent disabling hemiballism...
Central levodopa influx and the clinical motor response to levodopa in patients with Parkinson disease complicated with motor fluctuations and dyskinesiasNuria López-Ariztegui
Movement Disorders Research Unit, Hospital Universitario Gregorio Maranon, C Doctor Esquerdo 46, Madrid, Spain
Clin Neuropharmacol 32:321-5. 2009..To study the possible relationship between central levodopa influx and short-term antiparkinsonian and dyskinetic responses to levodopa in patients with Parkinson disease...
Conversion to controlled-release levodopa/carbidopa treatment and quality of life as measured by the Nottingham Health Profile. The STAR Study GroupP Martinez-Martin
Department of Neurology, Hospital Universitario de Getafe, Madrid
Neurologia 14:338-43. 1999..However, little is known about the effect of this strategy on the health-related quality of life (QoL)...
[Cardiac valvulopathy and dopamine agonist]F Grandas
Servicio de Neurologia, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Neurologia 22:870-81. 2007..To assess the possible relationship between treatment with dopamine agonists and cardiac fibrotic valvulopathy in Parkinson's disease, a systematic review of published articles describing this association was performed...
[Physiopathology of the dyskinesias induced by L-dopa]F Grandas
, , Madrid,
Rev Neurol 25:S151-6. 1997..Dyskinesias are one of most frequent motor complications of parkinsonian patients on chronic levodopa treatment. This article reviews their clinical characteristics, risk factors, pathophysiology and possible therapeutical approaches...
Risk factors for freezing of gait in Parkinson's diseaseAna Contreras
Movement Disorders Research Unit, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Maranon, Madrid, Spain
J Neurol Sci 320:66-71. 2012..It is not primarily associated with dopamine replacement therapy and may occur early in young patients...
Dopamine dysregulation syndrome after deep brain stimulation of the subthalamic nucleus in Parkinson's diseaseBeatriz De la Casa-Fages
Movement Disorders Research Unit, Hospital General Universitario Gregorio Maranon, Madrid, Spain
J Neurol Sci 312:191-3. 2012..The outcome of postoperative dopamine dysregulation syndrome is poor despite deep brain stimulation adjustments, attempts to reduce the dose of dopaminergic drugs and the addition of quetiapine or antidepressants...
Levodopa-induced dyskinesiasGiovanni Fabbrini
Department of Neurological Sciences University of Rome La Sapienza, Rome, Italy
Mov Disord 22:1379-89; quiz 1523. 2007..New rating measures to assess severity and disability related to dyskinesia are in the process of development and clinimetric testing...
Bupropion-induced parkinsonismFrancisco Grandas
Mov Disord 22:1830-1. 2007
