Research Topics
Species | Ana Gonzalez-PintoSummaryCountry: Spain Publications
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Publications
Psychosis and smoking cessation: difficulties in quitting associated with sex and substance abuseAna Gonzalez-Pinto
Biomedical Research Centre in Mental Health Net, Santiago Apostol Hospital, University of the Basque Country, Vitoria, Spain
Psychiatry Res 195:45-50. 2012..03, CI=0.001-0.77). Sex may act as a moderator in smoking cessation after a first psychotic episode. Smoking cessation interventions in these patients should consider sex differences and comorbidity with alcohol and cannabis use...
Number of prior episodes and the presence of depressive symptoms are associated with longer length of stay for patients with acute manic episodesManuel Martín-Carrasco
AstraZeneca Medical Department, Madrid, Spain
Ann Gen Psychiatry 11:7. 2012..abstract:..- Poor long-term prognosis in mixed bipolar patients: 10-year outcomes in the Vitoria prospective naturalistic study in SpainAna Gonzalez-Pinto
Biomedical Research Centre in Mental Health Net, CIBERSAM, Hospital Santiago Apostol, University of the Basque Country, Vitoria, Spain
J Clin Psychiatry 72:671-6. 2011..There have been few prospective long-term naturalistic studies of patients with mixed episodes of bipolar disorder. The aim of this study was to examine 10-year outcomes in patients with at least 1 mixed episode... - Validity and reliability of the Hamilton depression rating scale (5 items) for manic and mixed bipolar disordersAna Gonzalez-Pinto
CIBERSAM Stanley Institute International Mood Disorders Research Center, Hospital Santiago Apostol, University of the Basque Country, Vitoria, Alava, Spain
J Nerv Ment Dis 197:682-6. 2009..Best cut-off point of remission was: HAMD-21 < or =5 and HAMD-5 < or =1. HAMD-5 presents appropriate validity and reliability estimates. It is comparable to HAMD-21 and focuses more specifically on depressive symptoms... - Effectiveness of olanzapine monotherapy and olanzapine combination treatment in the long term following acute mania--results of a two year observational study in bipolar disorder (EMBLEM)Ana Gonzalez-Pinto
International Mood Disorders Research Centre, Centro de Investigación Biomédica en Red en Salud Mental CIBERSAM, Hospital Santiago Apostol, University of the Basque Country, Vitoria, Spain
J Affect Disord 131:320-9. 2011..This study compared the 2-year outcomes of patients with a manic/mixed episode of bipolar disorder taking olanzapine monotherapy or olanzapine in combination with other agents... 
Impact of cannabis and other drugs on age at onset of psychosisAna Gonzalez-Pinto
Department of Psychiatry, Santiago Apostol Hospital, CIBER SAM, Vitoria, Spain
J Clin Psychiatry 69:1210-6. 2008..The aim of this study was to investigate the relationship between age and cannabis use in patients with a first psychotic episode, and to analyze the mediating effect of comorbid use of other drugs and sex on age at onset of psychosis...- Different profile of substance abuse in relation to predominant polarity in bipolar disorder: The Vitoria long-term follow-up studyAna Gonzalez-Pinto
Biomedical Research Centre in Mental Health Net CIBERSAM, Hospital Santiago Apostol, University of the Basque Country, Vitoria, Spain
J Affect Disord 124:250-5. 2010..There is a need for comparisons of long-term outcomes in bipolar disorder patients with predominantly manic symptoms vs. predominantly depressive symptoms, especially the course of comorbid alcohol/substance abuse... - Epidemiology, diagnosis and management of mixed maniaAna Gonzalez-Pinto
Stanley International Mood Disorders Research Center, Hospital Santiago Apostol, University of the Basque Country, Vitoria, Spain
CNS Drugs 21:611-26. 2007..Importantly, patients with mixed manic episodes have more adverse events of psychopharmacological treatment. In some cases, electroconvulsive therapy is required... - Can positive family factors be protective against the development of psychosis?Ana Gonzalez-Pinto
Biomedical Research Center in Mental Health Net CIBERSAM, Hospital Santiago Apostol, Vitoria, Spain, University of the Basque Country
Psychiatry Res 186:28-33. 2011..This effect was not seen in subjects without a family history of psychosis. Therefore, our results support the importance of considering both family history of psychosis and family environment in the early stages of psychosis... - Cannabis and first-episode psychosis: different long-term outcomes depending on continued or discontinued useAna Gonzalez-Pinto
Department of Psychiatry, Centro de Investigación Biomédica en Red de Salud Mental, Hospital Santiago Apostol, University of the Basque Country, Olaguibel 29, Vitoria, Spain
Schizophr Bull 37:631-9. 2011.... - Increase in brain-derived neurotrophic factor in first episode psychotic patients after treatment with atypical antipsychoticsAna Gonzalez-Pinto
University of the Basque Country, Biomedical Research Center in Mental Health Net CIBERSAM, Hospital Santiago Apostol, Vitoria, Spain
Int Clin Psychopharmacol 25:241-5. 2010..Results suggest that olanzapine can offset the low BDNF levels at the onset of first psychotic episodes, and improving psychotic symptoms. The increase in BDNF levels may be its mechanism of action in improving positive symptoms... - Assessment of medication adherence in a cohort of patients with bipolar disorderA Gonzalez-Pinto
CIBERSAM Stanley International Mood Disorders Research Centre, Hospital Santiago Apostol, University of the Basque Country, Vitoria, Spain
Pharmacopsychiatry 43:263-70. 2010..This study aimed to identify factors associated with medication adherence in bipolar disorder (BPD) patients... - Decreased glutathione levels predict loss of brain volume in children and adolescents with first-episode psychosis in a two-year longitudinal studyDavid Fraguas
Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Madrid, Spain
Schizophr Res 137:58-65. 2012.... - Cognitive impairment is related to oxidative stress and chemokine levels in first psychotic episodesMónica Martínez-Cengotitabengoa
CIBERSAM, Centro de Investigación Biomédica en Red de Salud Mental, Spain
Schizophr Res 137:66-72. 2012.... - Progressive brain changes in children and adolescents with first-episode psychosisCelso Arango
Department of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Maranon, Centro de Investigación Biomédica en Red de Salud Mental, Madrid, Spain
Arch Gen Psychiatry 69:16-26. 2012..Progressive loss of brain gray matter (GM) has been reported in childhood-onset schizophrenia; however, it is uncertain whether these changes are shared by pediatric patients with different psychoses... - Manic and depressive symptoms and insight in first episode psychosisSaioa Aspiazu
Santiago Apostol Hospital, Stanley Institute International Mood Disorders Research Center, 03 RC 003, Centro de Investigación Biomédica en Red de Salud Mental CIBER sam, EHU UPV, Vitoria, Spain
Psychiatry Res 178:480-6. 2010..Finally, the model assessing the social consequences of having a mental disorder showed unawareness to be greater when manic symptoms and disease severity were high... - Validation and use of the functioning assessment short test in first psychotic episodesItxaso González-Ortega
Department of Psychiatry, Santiago Apostol Hospital, Vitoria, Spain
J Nerv Ment Dis 198:836-40. 2010..The FAST showed strong psychometric properties and is a valid instrument for use in clinical practice, clinical trials, and research settings in subjects with first psychotic episodes... - Trait and state attributes of insight in first episodes of early-onset schizophrenia and other psychoses: a 2-year longitudinal studyMara Parellada
Department of Psychiatry, Hospital General Universitario Gregorio Maranon, Ibiza 43, Madrid 28009, Spain
Schizophr Bull 37:38-51. 2011..Increasing evidence supports the important role of illness state and individual characteristics in insight... - Predominance of symptoms over time in early-onset psychosis: a principal component factor analysis of the Positive and Negative Syndrome ScaleMarta Rapado-Castro
Adolescent Unit, Department of Psychiatry, Hospital General Universitario Gregorio Maranon, C Ibiza 43, 28009 Madrid, Spain
J Clin Psychiatry 71:327-37. 2010..This study examined the dimensional structure of symptoms and the temporal stability of this structure during a 6-month follow-up... - The role of white matter damage in late onset bipolar disorderAriadna Besga
Santiago Apostol Hospital, Vitoria, Spain
Maturitas 70:160-3. 2011..In early life onset the aetiology of these lesions is less clear, although probably genetic factors are more important than cardiovascular factors. Understanding the aetiopathogenesis is of key importance when dealing with this disease... - Predictors of suicide in first-episode affective and nonaffective psychotic inpatients: five-year follow-up of patients from a catchment area in Vitoria, SpainAna Gonzalez-Pinto
Stanley Institute International Mood Disorders Research Center, Vitoria, Spain
J Clin Psychiatry 68:242-7. 2007.... - Bipolar disorder differences between genders: special considerations for womenPatricia Vega
Department of Psychiatry, Hospital Santiago Apostol, Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, University of the Basque Country, Vitoria, Spain
Womens Health (Lond Engl) 7:663-74; quiz 675-6. 2011..Moreover, a better understanding of how to treat women with bipolar disorder during pregnancy and lactation will undoubtedly lead to improved outcomes for both the mother and her child... - Antioxidant defense system and family environment in adolescents with family history of psychosisAna Gonzalez-Pinto
Stanley Institute International Mood Disorders Research Center, University of the Basque Country, Centro de Investigación Biomédica en Red de Salud Mental, 03 RC 003, Hospital Santiago, Vitoria, Spain
BMC Psychiatry 12:200. 2012.... - Reduced antioxidant defense in early onset first-episode psychosis: a case-control studyJuan Antonio Mico
Department of Neuroscience, Pharmacology and Psychiatry, School of Medicine, CIBERSAM, Centro de Investigación Biomédica en Red de Salud Mental University of Cádiz, Spain
BMC Psychiatry 11:26. 2011..Our objective is to determine the activity of the antioxidant defense system at admission in patients with early onset first psychotic episodes compared with a control group... - Gender differences in outcomes of acute mania: a 12-month follow-up studyLaia Miquel
Sant Joan de Deu SSM, Fundació Sant Joan de Déu, Centro de Investigación Biomédica en Red de Salud Mental, Catalonia, Spain
Arch Womens Ment Health 14:107-13. 2011..Women had a faster time to mania improvement and a higher risk of developing a depressive episode during the 12-month follow-up period... - Suicidal risk in bipolar I disorder patients and adherence to long-term lithium treatmentAna Gonzalez-Pinto
Stanley Institute International Mood Disorders Research Center, Vitoria, Spain
Bipolar Disord 8:618-24. 2006..Among the well-established treatments for bipolar disorder (BPD), lithium continues to offer an unusually broad spectrum of benefits that may include reduction of suicidal risk... - New treatment guidelines for acute bipolar mania: a critical reviewAlessandra M A Nivoli
Bipolar Disorders Program, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain
J Affect Disord 140:125-41. 2012..e.: electroconvulsive therapy)... - Plasma brain-derived neurotrophic factor levels, learning capacity and cognition in patients with first episode psychosisSonia Ruiz de Azúa
CIBERSAM Biomedical Research Center in Mental Health Net, University Hospital of Alava, University of the Basque Country, Vitoria, Spain
BMC Psychiatry 13:27. 2013..The aim of this study is to investigate whether Brain Derived Neurotrophic Factor (BDNF) levels are associated with cognitive impairment in FEP patients compared with healthy controls... - Working memory as a predictor of negative symptoms and functional outcome in first episode psychosisItxaso González-Ortega
Department of Psychiatry, Alava University Hospital Santiago, Department of Neurosciences, University of the Basque Country, CIBERSAM, Vitoria, Spain
Psychiatry Res 206:8-16. 2013..Negative symptoms mediated the relationship between working memory and outcome. Therefore, negative symptoms should be a primary target of treatment to improve functional outcomes... - Long-term efficacy of a psychological intervention program for patients with refractory bipolar disorder: a pilot studyAna González-Isasi
Department of Psychiatry, Santiago Apostol Hospital, Vitoria, Spain
Psychiatry Res 176:161-5. 2010..Therefore, the effectiveness of psychotherapy tends to increase with time, and this improvement is not significant until 12 months of follow-up... - DRD3, but not COMT or DRD2, genotype affects executive functions in healthy and first-episode psychosis adolescentsIgor Bombin
Adolescent Unit, Department of Psychiatry, Hospital General Universitario Gregorio Maranon, Madrid, Spain
Am J Med Genet B Neuropsychiatr Genet 147:873-9. 2008..The lack of association between COMT and DRD2 genotypes and cognition in our sample may be partially explained by the young age of the sample and the clinical heterogeneity of the patients... - Treatment nonadherence and neurocognitive impairment in bipolar disorderAnabel Martinez-Aran
Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Spain
J Clin Psychiatry 70:1017-23. 2009..This study aimed to investigate whether poor treatment adherence is associated with cognitive impairment in euthymic bipolar patients and whether other factors may be associated with both adherence and cognitive functioning... - Neurocognition in bipolar disorders--a closer look at comorbidities and medicationsVicent Balanzá-Martínez
Section of Psychiatry and Psychological Medicine, Department of Medicine, University of Valencia, CIBERSAM, Valencia, Spain
Eur J Pharmacol 626:87-96. 2010.... - Cognitive reserve as a predictor of two year neuropsychological performance in early onset first-episode schizophreniaElena de la Serna
Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Spain
Schizophr Res 143:125-31. 2013.... - Treatment of bipolar I rapid cycling patients during dysphoric mania with olanzapineAna Gonzalez-Pinto
Psychiatric Department, Santiago Apostol Hospital, Osakidetza Mental Health System, Vitoria, Spain
J Clin Psychopharmacol 22:450-4. 2002..96 kg in women, 2.20 +/- 2.28 kg in men). Our results suggest that olanzapine combined with mood stabilizers is safe and effective in the treatment of the manic and the depressive symptoms of dysphoric mania with a rapid cycling course... - Polarity index of pharmacological agents used for maintenance treatment of bipolar disorderDina Popovic
Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain
Eur Neuropsychopharmacol 22:339-46. 2012..The polarity index provides a measure of how much antidepressant versus antimanic a drug is in bipolar disorder prophylaxis, and may guide the choice of maintenance therapy in bipolar patients... - Purging behaviors and comorbidity as predictive factors of quality of life in anorexia nervosaAna Gonzalez-Pinto
Department of Psychiatry, Santiago Apostol Hospital, Osakidetza Mental Health System, Olaguibel 29, 01004 Vitoria, Spain
Int J Eat Disord 36:445-50. 2004..This study examined the predictive factors for the physical and mental summary components (PCS and MCS) of quality of life (SF-36) in patients with anorexia nervosa... - Dimensions of mania: differences between mixed and pure episodesAna Gonzalez-Pinto
Hospital Santiago Psychiatric Department Vitoria, Spain
Eur Psychiatry 19:307-10. 2004..The presence of at least five dimensions in mania has recently been established. This study extends previous findings by comparing the dimensions of pure vs. mixed mania... - The role of age in the development of Schneiderian symptoms in patients with a first psychotic episodeA Gonzalez-Pinto
Consultas Externas de Psiquiatria, Santiago Apostol Hospital, C Olaguibel 29, 01004 Vitoria Gasteiz, Spain
Acta Psychiatr Scand 109:264-8. 2004..The aim of this study was to test for a linear association between age and the probability of occurrence of FRS in patients with a first psychotic episode (FPE)... - Age-dependence of Schneiderian psychotic symptoms in bipolar patientsA Gonzalez-Pinto
Santiago Apostol Hospital, Consultas Externas de Psiquiatri a, C Olaguibel 29, 01004 Gasteiz, Vitoria, Spain
Schizophr Res 61:157-62. 2003.... - Principal components of maniaA Gonzalez-Pinto
Santiago Apostol Hospital, C Olaguibel, 29, 01004 Vitoria, Spain
J Affect Disord 76:95-102. 2003..The aim of this study was to investigate the dimensions of manic disorder by using classical scales to study the signs and symptoms of affective disorders... - [Involuntary hospitalization in the first psychotic episodes: associated factors]J L Figuerido
Servicio de Psiquiatria, Hospital Santiago Apostol, Servicio Vasco de Salud Osakidetza, Vitoria Gasteiz
Actas Esp Psiquiatr 28:275-8. 2000..The aim of this study is to determine which are the characteristics and associated factors in first psychotic episodes not due to medical illness... - New treatment guidelines for acute bipolar depression: a systematic reviewAlessandra M A Nivoli
Bipolar Disorders Program, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain
J Affect Disord 129:14-26. 2011..Many guidelines have been updated in the last 5 years, after the last review of bipolar disorder (BD) treatment guidelines... - Anticonvulsants in the treatment of aggression in the demented elderly: an updateBenedikt Amann
Benito Menni, CASM, Research Unit, CIBERSAM, St Boi de Llobregat, Barcelona, Spain
Clin Pract Epidemiol Ment Health 5:14. 2009..At least 50% of the dramatically growing number of patients with dementia exerts aggressive and agitated symptoms during the course of clinical progression, particularly at moderate clinical severity... - Efficacy and safety of venlafaxine-ECT combination in treatment-resistant depressionAna Gonzalez-Pinto
Hospital Santiago Apostol, Department of Psychiatry, Vitoria, Spain
J Neuropsychiatry Clin Neurosci 14:206-9. 2002..At higher doses, with propofol used as anesthetic, the possibility of asystole cannot be ruled out. A possible additive effect of high-dose venlafaxine and propofol-blocking sodium channels are discussed... - Validity and reliability of the Spanish versions of the Bech-Rafaelsen's mania and melancholia scales for bipolar disordersE Vieta
Clinic Hospital, University of Barcelona, IDIBAPS, CIBER SAM, Barcelona, Spain
Acta Psychiatr Scand 117:207-15. 2008..To assess classical psychometric properties of the Spanish versions of the Bech-Rafaelsen's mania (MAS) and melancholia (MES) scales... - Tardive dyskinesia associated with higher mortality in psychiatric patients: results of a meta-analysis of seven independent studiesJ Ballesteros
Department of Neuroscience, University of the Basque Country, Leioa, Vizcaya, Spain
J Clin Psychopharmacol 20:188-94. 2000..It remains to be elucidated whether it is a risk factor on its own or just a surrogate for any unknown organic liability...