Carmen Gomez

Summary

Country: Spain

Publications

  1. ncbi request reprint Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome
    Carmen Gomez
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Cadiz, 11003 Cadiz, Spain
    Front Biosci 12:1079-93. 2007
  2. ncbi request reprint Vitamin E at high doses improves survival, neurological performance, and brain mitochondrial function in aging male mice
    Ana Navarro
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 289:R1392-9. 2005
  3. ncbi request reprint Hippocampal mitochondrial dysfunction in rat aging
    Ana Navarro
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Plaza Fragela 9, 11003 Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 294:R501-9. 2008
  4. pmc High doses of vitamin E improve mitochondrial dysfunction in rat hippocampus and frontal cortex upon aging
    Ana Navarro
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Cadiz, Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 300:R827-34. 2011
  5. ncbi request reprint Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer
    Ana Navarro
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 286:R505-11. 2004
  6. ncbi request reprint Dietary thioproline decreases spontaneous food intake and increases survival and neurological function in mice
    Ana Navarro
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Cadiz, Cadiz, Spain
    Antioxid Redox Signal 9:131-41. 2007
  7. doi request reprint Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies
    Ana Navarro
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, Spain
    Free Radic Biol Med 46:1574-80. 2009
  8. doi request reprint Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity
    Ana Navarro
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Cadiz, Plaza Fragela 9, 11003 Cadiz, Spain
    J Bioenerg Biomembr 42:405-12. 2010
  9. ncbi request reprint Behavioral dysfunction, brain oxidative stress, and impaired mitochondrial electron transfer in aging mice
    Ana Navarro
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 282:R985-92. 2002

Detail Information

Publications9

  1. ncbi request reprint Pesticides and impairment of mitochondrial function in relation with the parkinsonian syndrome
    Carmen Gomez
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Cadiz, 11003 Cadiz, Spain
    Front Biosci 12:1079-93. 2007
    ..This regulation and the role of mitochondrial NO diffusion as a signal for mitochondrial biogenesis could have a role in the etiopathology of Parkinson's disease...
  2. ncbi request reprint Vitamin E at high doses improves survival, neurological performance, and brain mitochondrial function in aging male mice
    Ana Navarro
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 289:R1392-9. 2005
    ..58-0.99, P < 0.01), and the rates of respiration and of complex I and IV activities correlated positively (r2 = 0.74-0.80, P < 0.01) with success in the behavioral tests and with maximal life span...
  3. ncbi request reprint Hippocampal mitochondrial dysfunction in rat aging
    Ana Navarro
    Departamento de Bioquimica y Biologia Molecular, Facultad de Medicina, Plaza Fragela 9, 11003 Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 294:R501-9. 2008
    ..A significant statistical correlation was observed between mitochondrial oxidative damage and enzymatic activity. Mitochondrial dysfunction with shortage of energy supply is considered a likely cause of dysfunction in aged hippocampus...
  4. pmc High doses of vitamin E improve mitochondrial dysfunction in rat hippocampus and frontal cortex upon aging
    Ana Navarro
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Cadiz, Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 300:R827-34. 2011
    ..Aging decreased (19%) hippocampus mitochondrial mass, an effect that was restored by vitamin E. High doses of vitamin E seem to sustain mitochondrial biogenesis in synaptic areas...
  5. ncbi request reprint Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer
    Ana Navarro
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 286:R505-11. 2004
    ..Moderate exercise, started at young age in mice, increased life span, decreased oxidative stress, and prevented the decline of cytochrome oxidase activity and behavioral performance at middle age but not at old age...
  6. ncbi request reprint Dietary thioproline decreases spontaneous food intake and increases survival and neurological function in mice
    Ana Navarro
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Cadiz, Cadiz, Spain
    Antioxid Redox Signal 9:131-41. 2007
    ..It is surmised that thioproline induces an anorexic effect associated with improved survival and neurological function through a decreased oxidative damage and regulation that may involve hypothalamic appetite centers...
  7. doi request reprint Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies
    Ana Navarro
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, Spain
    Free Radic Biol Med 46:1574-80. 2009
    ..The adaptive response would partially compensate for mitochondrial dysfunction in these neurodegenerative diseases and would afford a human evolutionary response to shortage of ATP in the frontal cortex...
  8. doi request reprint Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity
    Ana Navarro
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Cadiz, Plaza Fragela 9, 11003 Cadiz, Spain
    J Bioenerg Biomembr 42:405-12. 2010
    ..This fact is interpreted as an indication of mtNOS being structurally adjacent to complex I with an intermolecular mtNOS-complex I hydrophobic bonding that is stronger at high Δψ and weaker at low Δψ...
  9. ncbi request reprint Behavioral dysfunction, brain oxidative stress, and impaired mitochondrial electron transfer in aging mice
    Ana Navarro
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Cadiz, 11003 Cadiz, Spain
    Am J Physiol Regul Integr Comp Physiol 282:R985-92. 2002
    ..The cumulative toxic effects of oxyradicals are considered the molecular mechanism of the behavioral deficits observed on aging...