Research Topics
| J C Gomez-VillamandosSummaryCountry: Spain Publications
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Detail Information
Publications
Pathogenic mechanisms implicated in the intravascular coagulation in the lungs of BVDV-infected calves challenged with BHV-1María A Risalde
Department of Comparative Pathology, Veterinary Faculty, University of Córdoba Agrifood Campus of International Excellence ceiA3, Edificio Sanidad Animal, Campus de Rabanales, Córdoba 14014, Spain
Vet Res 44:20. 2013..Moreover, animals pre-inoculated with BVDV displayed an alteration in the response of pro-inflammatory cytokines (TNFα and IL-1), which play a key role in activating the immune response, as well as in the local cell-mediated response...- Pathology of African swine fever: the role of monocyte-macrophageJ C Gomez-Villamandos
Department of Comparative Pathology, Veterinary Faculty, University of Córdoba Agrifood Campus of International Excellence ceiA3, Edificio Sanidad Animal, Campus de Rabanales, 14014 Cordoba, Spain
Virus Res 173:140-9. 2013..Levels of IFN-β and -γ are increased from initial phase of acute ASF. Anti-inflammatory response, represented by increased level of IL-10, is observed also, although in the final phase of acute ASF only... 
Classical Swine Fever: pathology of bone marrowJ C Gomez-Villamandos
Departamento Anatomía y Anatomía Patológica Comparadas, Edificio de Sanidad Animal, Campus Universitario de Rabanales, Cordoba, Spain
Vet Pathol 40:157-63. 2003..Granulocyte changes would lead to the appearance of circulating immature forms, whereas lymphocyte apoptosis in bone marrow would contribute to lymphopenia...- Neuropathologic study of experimental classical swine feverJ C Gomez-Villamandos
Departamento de Anatomia y Anatomia Patologica Comparadas, Facultad de Veterinaria, Universidad de Cordoba, Edificio de Sanidad Animal, Campus de Rabanales, 14014, Cordoba Spain
Vet Pathol 43:530-40. 2006..However, the link between viral infection and the presence of cell infiltrate was far from clear... - Evolution of T lymphocytes and cytokine expression in classical swine fever (CSF) virus infectionP J Sánchez-Cordón
Departamento de Anatomia y Anatomia Patologica Comparadas, Facultad de Veterinaria, Universidad de Cordoba, Edificio de Sanidad Animal, Campus de Rabanales, 14014 Cordoba, Spain
J Comp Pathol 132:249-60. 2005.... - Expression of proinflammatory cytokines by hepatic macrophages in acute classical swine feverA Nunez
Departamento de Anatomía Patológica Comparada, Facultad de Veterinaria, Universidad de Córdoba Edifico de Sanidad Animal, Campus Universitario de Rabanales, 14014, Cordoba, Spain
J Comp Pathol 133:23-32. 2005.... - African swine fever and classical swine fever: a review of the pathogenesisJ C Gomez-Villamandos
Dpto Anatomía, Patologica, Facultad de Veterinaria, Cordoba, Spain
Dtsch Tierarztl Wochenschr 110:165-9. 2003..The causes of the thrombocytopenia and the mechanisms of the haemorrhages, which are characteristic in both infections, are described. Apoptotic cell death is regarded as the predominant cause of lymphopenia in both virus infections... - Quantification and determination of spread mechanisms of bovine viral diarrhoea virus in blood and tissues from colostrum-deprived calves during an experimental acute infection induced by a non-cytopathic genotype 1 strainM Pedrera
Department of Comparative Pathology, Veterinary Faculty, University of Córdoba Agrifood Excellence International Campus ceiA3, Edificio Sanidad Animal, Campus de Rabanales, Cordoba, Spain
Transbound Emerg Dis 59:377-84. 2012..This fact could influence in the appearance of bovine respiratory diseases because of the capacity of BVDV for enhancing susceptibility to secondary infections... - A histopathologic, immunohistochemical, and ultrastructural study of the intestine in pigs inoculated with classical swine fever virusP J Sánchez-Cordón
Departamento de Anatomia Patologica, Universidad de Cordoba, Campus Universitario de Rabanales, Edificio de Sanidad Animal, Spain
Vet Pathol 40:254-62. 2003..This suggests that monocytes-macrophages play an important role in the pathogenesis of intestinal lesions. An understanding of the function of these cells will require additional study... - Lymphocyte apoptosis and thrombocytopenia in spleen during classical swine fever: role of macrophages and cytokinesP J Sánchez-Cordón
Departamento de Anatomia y Anatomia Patologica Comparadas, Facultad de Veterinaria, Universidad de Córdoba Edificio de Sanidad Animal, Campus de Rabanales, 14014, Cordoba, Spain
Vet Pathol 42:477-88. 2005.... - Development of microscopic lesions in splenic cords of pigs infected with African swine fever virusL Carrasco
Departamento de Anatomia y Anatomia Patologica Comparadas, Facultad de Veterinaria, Universidad de Cŕdoba, Spain
Vet Res 28:93-9. 1997..It is likely that the ASF virus replication, and consequent cytopathic effects, observed in the fixed macrophages of splenic cords, may be responsible for the fibrin deposition... - Pathogenesis of classical swine fever: renal haemorrhages and erythrodiapedesisJ C Gomez-Villamandos
Departamento de Anatomia Patologica, Universidad de Cordoba, Campus Universitario de Rabanales, Carretera de Madrid, 14014 Cordoba, Spain
J Comp Pathol 123:47-54. 2000..The results suggested that mast cell degranulation was linked to activation of the complement system... - The role of pulmonary intravascular macrophages in the pathogenesis of African horse sicknessL Carrasco
Departmento de Anatomía y Anatomía Patológica Comparadas, Facultad de Veterinaria, Universidad de Cordoba, Avenida Medina Azahara s n, Cordoba, 14005, Spain
J Comp Pathol 121:25-38. 1999..This suggested that the PIMs, once activated, contributed to these vascular changes by releasing chemical inflammatory mediators... - Proinflammatory cytokines induce lymphocyte apoptosis in acute African swine fever infectionF J Salguero
Departamento de Anatomia y Anatomia Patologica Comparadas, Edificio de Sanidad Animal, Campus Universitario de Rabanales, Universidad de Cordoba, 14014 Cordoba, Spain
J Comp Pathol 132:289-302. 2005.... - Subcellular changes in the tonsils of pigs infected with acute African swine fever virusJ C Gomez-Villamandos
Dpto Anatomía y Anatomía Patológica, Facultad de Veterinaria, Universidad de Cordoba, Spain
Vet Res 28:179-89. 1997.... - Pathogenesis of African horse sickness: ultrastructural study of the capillaries in experimental infectionJ C Gomez-Villamandos
Departamento de Anatomia y Anatomia Patologica Comparadas, Facultad de Veterinaria, Universidad de Cordoba, Avenida de Medina Azahara 7, Cordoba, 14005, USA
J Comp Pathol 121:101-16. 1999.... - Hepatic immune response in calves during acute subclinical infection with bovine viral diarrhoea virus type 1M A Risalde
Department of Comparative Pathology, University of Cordoba, Cordoba, Spain
Vet J 190:e110-6. 2011..Serum haptoglobin and serum amyloid A increased transiently at 12dpi. Upregulation of some pro-inflammatory cytokines by hepatic macrophages is evident in subclinical acute BVDV type 1 infection in calves... - Glomerulonephritis associated with simultaneous canine adenovirus-1 and Dirofilaria immitis infection in a dogP J Sánchez-Cordón
Departamento Anatomía Patológica Comparada, Facultad de Veterinaria, Universidad de Cordoba, Spain
J Vet Med B Infect Dis Vet Public Health 49:235-9. 2002.... - The role of B cells in the immune response to pestivirus (classical Swine Fever virus)P J Sánchez-Cordón
Departamento de Anatomia y Anatomia Patologica Comparadas, Facultad de Veterinaria, Universidad de Cordoba, Edificio de Sanidad Animal, Campus de Rabanales, 14014 Cordoba, Spain
J Comp Pathol 135:32-41. 2006..These changes may have influenced the late appearance of virus-specific antibodies in the study, as well as the progressive increase of immunoglobulins... - Reovirus infection in psittacine birds (Psittacus erithacus): morphologic and immunohistochemical studyP J Sánchez-Cordón
Departamento de Anatomia Patologica, Facultad de Veterinaria, Universidad de Cordoba, Spain
Avian Dis 46:485-92. 2002.... - Potential role of proinflammatory cytokines in the pathogenetic mechanisms of vascular lesions in goats naturally infected with bluetongue virus serotype 1P J Sánchez-Cordón
Department of Comparative Pathology, Veterinary Faculty, University of Córdoba Agrifood Excellence International Campus ceiA3, Cordoba, Spain Center of Animal Health Surveillance VISAVET and Animal Health Department, Veterinary Faculty, Complutense University of Madrid, Madrid, Spain Department of Pathology and Host Susceptibility, Animal Health and Veterinary Laboratories Agency AHVLA, New Haw, UK
Transbound Emerg Dis 60:252-62. 2013.... - Hepatitis associated with herpes viral infection in the tortoise (Testudo horsfieldii)J Hervas
Departmento Anatomia Patològica Comparada, Facultad de Veterinaria, Universidad de Cordoba, Spain
J Vet Med B Infect Dis Vet Public Health 49:111-4. 2002..This article is the first description of a viral hepatitis in Testudo spp. with lesions compatible with herpesvirus infection, with no clinical signs or lesions in the respiratory system, oral cavity or other organs... - Immunohistochemical detection of bluetongue virus in fixed tissueP J Sánchez-Cordón
Department of Comparative Pathology, Veterinary Faculty, University of Cordoba, Edificio Sanidad Animal, Campus de Rabanales, 14014 Cordoba, Spain
J Comp Pathol 143:20-8. 2010..The immunohistochemical method described will be a useful tool for future research... - Morphological and immunohistochemical changes in splenic macrophages of pigs infected with classical swine feverJ C Gomez-Villamandos
Departamento Anatomia Patologica, Facultad de Veterinaria, Campus Universitario de Rabaneles, 14014 Cordoba, Spain
J Comp Pathol 125:98-109. 2001..Moreover, the secretory changes that occurred in macrophages in the initial phase of the infection suggested that macrophages release chemical mediators capable of modulating pathogenesis... - Characterization of apoptosis pathways (intrinsic and extrinsic) in lymphoid tissues of calves inoculated with non-cytopathic bovine viral diarrhoea virus genotype-1M Pedrera
Department of Comparative Pathology, Veterinary Faculty, University of Cordoba, Edificio Sanidad Animal, Campus de Rabanales, 14014 Cordoba, Spain
J Comp Pathol 146:30-9. 2012.... - Response of proinflammatory and anti-inflammatory cytokines in calves with subclinical bovine viral diarrhea challenged with bovine herpesvirus-1M A Risalde
Department of Comparative Pathology, Veterinary Faculty, University of Córdoba Agrifood Campus of International Excellence ceiA3, Campus de Rabanales, 14014, Cordoba, Spain
Vet Immunol Immunopathol 144:135-43. 2011..This alteration in the kinetic and magnitude of these cytokines, involved in cytotoxic mechanisms responsible for limiting the spread of secondary pathogens, facilitated the dissemination of BHV-1.1 in BVDV-infected calves... - Atoxoplasma spp. infection in captive canaries (Serinus canaria)P J Sánchez-Cordón
Departamento de Anatomia y Anatomia Patologica Comparadas, Facultad de Veterinaria, Universidad de Cordoba, Edificio de Sanidad Animal, Campus de Rabanales, 14014 Cordoba, Spain
J Vet Med A Physiol Pathol Clin Med 54:23-6. 2007..An usual finding was the presence of infected mononuclear cells adhered to the endothelium of the blood vessels in lung. The diagnosis was confirmed by ultrastructural examination of reprocessed paraffin-embedded tissues... - Classical swine fever: morphological and morphometrical study of pulmonary intravascular macrophagesL Carrasco
, Edificio de Sanidad Animal, Facultad de Veterinaria, , 14014, Spain
J Comp Pathol 125:1-7. 2001..The results obtained suggest that macrophage activation and the subsequent release of pro-inflammatory mediators play an important role in the pathogenesis of CSF... - Focal mesangial-sclerosing glomerulonephritis and acute-spontaneous infectious canine hepatitis: structural, immunohistochemical and subcellular studiesJ Hervas
Dpto Anatomía Patológica, Facultad de Veterinaria, Cordoba, Spain
Vet Immunol Immunopathol 57:25-32. 1997.... - Morphological changes and virus distribution in the ileum of colostrum-deprived calves inoculated with non-cytopathic bovine viral diarrhoea virus genotype-1M Pedrera
Department of Comparative Pathology, Veterinary Faculty, University of Cordoba, Edificio Sanidad Animal, Campus de Rabanales, Cordoba, Spain
J Comp Pathol 141:52-62. 2009..Characterization of the indirect pathogenic mechanisms involved in the lymphoid depletion associated with BVDV infection will require additional study... - An immunohistochemical study of the tonsils in pigs with acute African swine fever virus infectionM Fernández de Marco
Departamento de Anatomia y Anatomia Patologica Comparadas, Facultad de Veterinaria, Universidad de Cordoba, 14014 Cordoba, Spain
Res Vet Sci 83:198-203. 2007..With these results, we can conclude that the tonsil is suffering similar lesions than those observed in other lymphoid organs in acute African swine fever, even when the route of inoculation is the intramuscular and not oral-nasal...