Diego Gómez-Nicola

Summary

Country: Spain

Publications

  1. doi request reprint CCR7 is expressed in astrocytes and upregulated after an inflammatory injury
    Diego Gómez-Nicola
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Cajal Institute, CSIC, Avda Doctor Arce, 37, 28002, Madrid, Spain
    J Neuroimmunol 227:87-92. 2010
  2. ncbi request reprint Regulation by GD3 of the proinflammatory response of microglia mediated by interleukin-15
    Diego Gómez-Nicola
    Neural Plasticity Department, Instituto Ramón y Cajal de Neurobiología, CSIC, Madrid, Spain
    J Neurosci Res 83:754-62. 2006
  3. pmc Glioma growth inhibition by neurostatin and O-But GD1b
    Beatriz Valle-Argos
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Instituto Cajal, Madrid, Spain
    Neuro Oncol 12:1135-46. 2010
  4. pmc Interleukin-15 regulates proliferation and self-renewal of adult neural stem cells
    Diego Gómez-Nicola
    Functional and Systems Neurobiology Department, Cajal Institute CSIC, Madrid, Spain
    Mol Biol Cell 22:1960-70. 2011
  5. doi request reprint Cannabinoid agonist WIN 55,212-2 prevents the development of paclitaxel-induced peripheral neuropathy in rats. Possible involvement of spinal glial cells
    Elisa Burgos
    Department of Pharmacology and Nutrition, Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorcon, Madrid, Spain
    Eur J Pharmacol 682:62-72. 2012
  6. doi request reprint Neurostatin blocks glioma cell cycle progression by inhibiting EGFR activation
    Beatriz Valle-Argos
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Cajal Institute, CSIC, 28002 Madrid, Spain
    Mol Cell Neurosci 46:89-100. 2011
  7. doi request reprint Aggravated experimental autoimmune encephalomyelitis in IL-15 knockout mice
    Diego Gómez-Nicola
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Instituto Cajal, Consejo Superior de Investigaciones Cientificas, 28002 Madrid, Spain
    Exp Neurol 222:235-42. 2010
  8. doi request reprint Synthesis and characterization of neurostatin-related compounds with high inhibitory activity of glioma growth
    Beatriz Valle-Argos
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Cajal Institute CSIC, Avda Doctor Arce, 37, 28002, Madrid, Spain
    Eur J Med Chem 45:2034-43. 2010
  9. doi request reprint Interleukin 15 expression in the CNS: blockade of its activity prevents glial activation after an inflammatory injury
    Diego Gómez-Nicola
    Functional and Systems Neurobiology Department, Cajal Institute, CSIC, Madrid, Spain
    Glia 56:494-505. 2008
  10. pmc Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System
    Manuel Nieto-Sampedro
    Instituto Cajal de Neurobiologia, CSIC, 28002 Madrid, Spain
    Clin Med Insights Oncol 5:265-314. 2011

Collaborators

Detail Information

Publications10

  1. doi request reprint CCR7 is expressed in astrocytes and upregulated after an inflammatory injury
    Diego Gómez-Nicola
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Cajal Institute, CSIC, Avda Doctor Arce, 37, 28002, Madrid, Spain
    J Neuroimmunol 227:87-92. 2010
    ..Our results indicate that CCR7 is playing an important role for the intercellular communication during the inflammatory activation in the CNS...
  2. ncbi request reprint Regulation by GD3 of the proinflammatory response of microglia mediated by interleukin-15
    Diego Gómez-Nicola
    Neural Plasticity Department, Instituto Ramón y Cajal de Neurobiología, CSIC, Madrid, Spain
    J Neurosci Res 83:754-62. 2006
    ..The antiinflammatory properties of GD3 could be significant in the treatment of pain subsequent to CNS damage...
  3. pmc Glioma growth inhibition by neurostatin and O-But GD1b
    Beatriz Valle-Argos
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Instituto Cajal, Madrid, Spain
    Neuro Oncol 12:1135-46. 2010
    ....
  4. pmc Interleukin-15 regulates proliferation and self-renewal of adult neural stem cells
    Diego Gómez-Nicola
    Functional and Systems Neurobiology Department, Cajal Institute CSIC, Madrid, Spain
    Mol Biol Cell 22:1960-70. 2011
    ..The results show that IL-15 is a key regulator of neurogenesis in the adult and is essential to understanding diseases with an inflammatory component...
  5. doi request reprint Cannabinoid agonist WIN 55,212-2 prevents the development of paclitaxel-induced peripheral neuropathy in rats. Possible involvement of spinal glial cells
    Elisa Burgos
    Department of Pharmacology and Nutrition, Faculty of Health Sciences, Rey Juan Carlos University, 28922 Alcorcon, Madrid, Spain
    Eur J Pharmacol 682:62-72. 2012
    ....
  6. doi request reprint Neurostatin blocks glioma cell cycle progression by inhibiting EGFR activation
    Beatriz Valle-Argos
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Cajal Institute, CSIC, 28002 Madrid, Spain
    Mol Cell Neurosci 46:89-100. 2011
    ..The antitumoral actions described here point to neurostatin as a novel and promising chemotherapeutic agent for glioma treatment...
  7. doi request reprint Aggravated experimental autoimmune encephalomyelitis in IL-15 knockout mice
    Diego Gómez-Nicola
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Instituto Cajal, Consejo Superior de Investigaciones Cientificas, 28002 Madrid, Spain
    Exp Neurol 222:235-42. 2010
    ..How these findings are contributing to the aggravated EAE development in IL-15 KO mice remain unclear and need to be further investigated...
  8. doi request reprint Synthesis and characterization of neurostatin-related compounds with high inhibitory activity of glioma growth
    Beatriz Valle-Argos
    Neural Plasticity Group, Functional and Systems Neurobiology Department, Cajal Institute CSIC, Avda Doctor Arce, 37, 28002, Madrid, Spain
    Eur J Med Chem 45:2034-43. 2010
    ..These results open the possibility for the application of the neurostatin-related compounds to in-vivo tumoral models...
  9. doi request reprint Interleukin 15 expression in the CNS: blockade of its activity prevents glial activation after an inflammatory injury
    Diego Gómez-Nicola
    Functional and Systems Neurobiology Department, Cajal Institute, CSIC, Madrid, Spain
    Glia 56:494-505. 2008
    ..Because IL-15 appears to modulate the inflammatory environment acutely generated after CNS injury, regulating IL-15 expression seems a clear antiinflammatory therapy to improve the outcome of neurodegenerative diseases and CNS trauma...
  10. pmc Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System
    Manuel Nieto-Sampedro
    Instituto Cajal de Neurobiologia, CSIC, 28002 Madrid, Spain
    Clin Med Insights Oncol 5:265-314. 2011
    ..Because neurostatins and their analogues show specific activity and no toxicity for normal cells, a clinical trial would be the logical next step...