Research Topics
| J P GisbertSummaryCountry: Spain Publications
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Publications
Risk assessment and outpatient management in bleeding peptic ulcerJavier P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa, Madrid, Spain
J Clin Gastroenterol 40:129-34. 2006....
Comparative effectiveness of azathioprine in Crohn's disease and ulcerative colitis: prospective, long-term, follow-up study of 394 patientsJ P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain
Aliment Pharmacol Ther 28:228-38. 2008..The long-term efficiacy for thiopurinic drugs in Crohn's disease (CD), and particularly in ulcerative colitis (UC), has been insufficiently studied...
Pathophysiological bases of eosinophilic esophagitis therapyRicardo Moreno-Borque
Alergología Clínica Servicio de Medicina Interna, Hospital Rey Juan Carlos I, Mostoles, Madrid, Spain
Inflamm Allergy Drug Targets 12:46-53. 2013..Prolonged treatment is advised for EoE because it recurs frequently, particularly on discontinuation of therapy. Experimental treatments using immunotherapy are being investigated, but their safety and efficacy are yet to be defined...
Long-term follow-up of 1,000 patients cured of Helicobacter pylori infection following an episode of peptic ulcer bleedingJ P Gisbert
Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa, Madrid, Spain
Am J Gastroenterol 107:1197-204. 2012..To evaluate the effect of Helicobacter pylori (H. pylori) eradication on ulcer bleeding recurrence in a prospective, long-term study including 1,000 patients...
[Helicobacter pylori-related diseases]Javier P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa IP, Madrid, Spain
Gastroenterol Hepatol 35:12-25. 2012..Even after three eradication therapies have failed, an empirical rescue therapy (with rifabutin) can be effective. H. pylori reinfection is highly frequent in developing countries, probably due to intrafamilial transmission...
[Helicobacter pylori-related diseases: dyspepsia, ulcers and gastric cancer]Javier P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de Princesa, Instituto de Investigación Sanitaria Princesa IP, Madrid, Espana
Gastroenterol Hepatol 34:15-26. 2011..Even after three previous H. pylori eradication failures, an empirical fourth-line rescue treatment with rifabutin may be effective...
Review article: the effectiveness of standard triple therapy for Helicobacter pylori has not changed over the last decade, but it is not good enoughJ P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa IP y Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Madrid, Spain
Aliment Pharmacol Ther 34:1255-68. 2011..Therefore, it is evident that new strategies to improve first-line treatment are urgently needed...
[Anti-neutrophil cytoplasmic antibodies in the diagnosis of ulcerative colitis and Crohn's disease]Javier P Gisbert
Servicio de Aparato Digestivo Hospital Universitario de La Princesa Madrid España
Med Clin (Barc) 122:134-5. 2004..Patients and method: pANCA were determined by indirect immunofluorescence and positive results were confirmed by ELISA...
[Systematic reviews and meta-analyses: how should they be performed, evaluated and used?]J P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Spain
Gastroenterol Hepatol 27:129-49. 2004
Empirical rescue therapy after Helicobacter pylori treatment failure: a 10-year single-centre study of 500 patientsJ P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa and Ciberehd, Universidad Autonoma, Madrid, Spain
Aliment Pharmacol Ther 27:346-54. 2008..Several 'rescue' therapies have been recommended to eradicate Helicobacter pylori, but they still fail in >20% of the cases, and these patients constitute a therapeutic dilemma...
Helicobacter pylori and perforated peptic ulcer prevalence of the infection and role of non-steroidal anti-inflammatory drugsJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Playa de Mojácar 29, Urb Bonanza, 28669 Boadilla del Monte, Madrid, Spain
Dig Liver Dis 36:116-20. 2004....
"Rescue" regimens after Helicobacter pylori treatment failureJavier P Gisbert
Gastroenterology Unit, Hospital de la Princesa, Madrid, Spain
World J Gastroenterol 14:5385-402. 2008..Therefore, the attitude in H pylori eradication therapy failure, even after two or more unsuccessful attempts, should be to fight and not to surrender...
Prevalence of hepatitis C virus infection in porphyria cutanea tarda: systematic review and meta-analysisJavier P Gisbert
Servicio de Gastroenterología y Hepatología, Universidad Autonoma de Madrid, Hospital Universitario de la Princesa, Diego de Leon, 62 28006, Madrid, Spain
J Hepatol 39:620-7. 2003..To conduct a systematic review and meta-analysis on the prevalence of hepatitis C virus (HCV) infection in porphyria cutanea tarda (PCT)...
[Thiopurine methyltransferase activity and myelosuppression in inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine]Javier P Gisbert
Servicio de Aparato Digestivo Hospital Universitario de la Princesa Universidad Autónoma Madrid Spain
Med Clin (Barc) 121:1-5. 2003....
Validation of the 13c-urea breath test for the initial diagnosis of helicobacter pylori infection and to confirm eradication after treatmentJ P Gisbert
Servicio de Aparato Digestivo Hospital de la Princesa Madrid Spain
Rev Esp Enferm Dig 95:121-6, 115-20. 2003..Our objective was to validate the UBT (TAU-KIT) both as an initial diagnostic method for the detection of H. pylori infection and as a method to confirm eradication...
[The role of anti-neutrophil cytoplasmic antibodies (ANCA) and anti-Saccharomyces cerevisiae antibodies (ASCA) in inflammatory bowel disease]J P Gisbert
Servicio de Aparato Digestivo. Hospital Universitario de la Princesa. Madrid. Spain
Gastroenterol Hepatol 26:312-24. 2003
[Cyclooxygenase-2 and gastroduodenal lesions. Any relationship with Helicobacter pylori ? A systematic review]Javier P Gisbert
Servicio de Aparato Digestivo Hospital Universitario de La Princesa Madrid España
Med Clin (Barc) 120:550-8. 2003
Fecal calprotectin and lactoferrin for the prediction of inflammatory bowel disease relapseJavier P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Madrid, Spain
Inflamm Bowel Dis 15:1190-8. 2009....
[Comparison between two 13C-urea breath tests for the diagnosis of Helicobacter pylori infection: isotope ratio mass spectrometer versus infrared spectrometer]J P Gisbert
Servicios de Aparato Digestivo Hospital Universitario de la Princesa Madrid Spain
Gastroenterol Hepatol 26:141-6. 2003..To compare the accuracy of the breath test using the isotope ratio mass spectrometer (IRMS) versus the nondispersive isotope-selective infrared spectrometer (NDIRS) in the diagnosis of Helicobacter pylori infection...
Questions and answers on the role of fecal lactoferrin as a biological marker in inflammatory bowel diseaseJavier P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain
Inflamm Bowel Dis 15:1746-54. 2009..Finally, in patients with Crohn's disease who have undergone ileocolonic resection, those with higher lactoferrin fecal levels might be more prone to postsurgical recurrence...
Review article: is there an optimal therapeutic regimen for antimitochondrial antibody-negative primary biliary cirrhosis (autoimmune cholangitis)?J P Gisbert
Servicio de Gastroenterología y Hepatología, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Diego de Leon 62, E 28006 Madrid, Spain
Aliment Pharmacol Ther 17:17-27. 2003..However, ursodeoxycholic acid may be given when histology reveals bile duct lesions, whereas immunosuppressive therapy should probably be reserved for patients exhibiting interface hepatitis...
Lack of benefit of treating Helicobacter pylori infection in patients with functional dyspepsia. Randomized one-year follow-up studyJavier P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Hepatogastroenterology 51:303-8. 2004..To assess whether H. pylori therapy is significantly better than control therapy in patients with functional dyspepsia, and to assess whether curing the infection relieves symptoms of dyspepsia...
Eradication of Helicobacter pylori for the prevention of peptic ulcer rebleedingJavier P Gisbert
Department of Gastroenterology, Hospital de la Princesa, Madrid, Spain
Helicobacter 12:279-86. 2007..To evaluate the effect of Helicobacter pylori eradication on ulcer bleeding recurrence in a prospective, long-term study including more than 400 patients...
[Eradication treatment of Helicobacter pylori. Recommendations of the II Spanish Consensus Conference]Javier P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
Med Clin (Barc) 125:301-16. 2005
Helicobacter pylori "rescue" therapy after failure of two eradication treatmentsJavier P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Helicobacter 10:363-72. 2005....
Helicobacter pylori first-line treatment and rescue options in patients allergic to penicillinJ P Gisbert
Department of Gastroenterology, La Princesa University Hospital, Madrid, Spain
Aliment Pharmacol Ther 22:1041-6. 2005..Helicobacter pylori eradication is a challenge in patients allergic to penicillin, especially those who have failed a first-eradication trial...
[Prevention of bleeding recurrence in peptic ulcer by Helicobacter pylori eradication]J P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
Gastroenterol Hepatol 28:567-75. 2005
13C-urea breath test in the management of Helicobacterpylori infectionJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Playa de Mojácar 29, Urb Bonanza, Boadilla del Monte, Madrid 28669, Spain
Dig Liver Dis 37:899-906. 2005..pylori infection in patients with upper gastrointestinal bleeding, urea breath test seems not to be negatively influenced by the presence of this complication...
Is there any correlation between 13C-urea breath test values and response to first-line and rescue Helicobacter pylori eradication therapies?J P Gisbert
Gastroenterology Unit, La Princesa University Hospital, Autonomous University, Playa de Mojácar 29 Urb Bonanza, 28669 Boadilla del Monte, Madrid, Spain
Dig Liver Dis 38:254-9. 2006..To study if there is a correlation between 13C-urea breath test values prior to treatment and the response to first-line and rescue Helicobacter pylori eradication therapies...
7-day rescue therapy with ranitidine bismuth citrate after Helicobacter pylori treatment failureJ P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
Aliment Pharmacol Ther 21:1249-53. 2005..Quadruple rescue therapy requires a complex scheme with four drugs...
Systematic review and meta-analysis: is 1-week proton pump inhibitor-based triple therapy sufficient to heal peptic ulcer?J P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Aliment Pharmacol Ther 21:795-804. 2005....
Systematic review and meta-analysis: levofloxacin-based rescue regimens after Helicobacter pylori treatment failureJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Aliment Pharmacol Ther 23:35-44. 2006..A quadruple therapy has been generally recommended as rescue regimen for Helicobacter pylori eradication failures...
[Monitoring of thiopurine methyltransferase and thiopurine metabolites to optimize azathioprine therapy in inflammatory bowel disease]Javier P Gisbert
Servicio de Aparato Digestivo Hospital Universitario de La Princesa Universidad Autónoma Madrid España
Gastroenterol Hepatol 29:568-83. 2006....
Systematic review: Infliximab therapy in ulcerative colitisJ P Gisbert
Gastroenterology Unit, La Princesa University Hospital, Autonomous University, Madrid, Spain
Aliment Pharmacol Ther 25:19-37. 2007..To perform a systematic review and meta-analysis on the efficacy and tolerance of infliximab in ulcerative colitis...
Esomeprazole-based therapy in Helicobacter pylori eradication: a meta-analysisJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Playa de Mojácar 29 Urb Bonanza, 28669 Boadilla del Monte, Madrid, Spain
Dig Liver Dis 36:253-9. 2004....
Pantoprazole based therapies in Helicobacter pylori eradication: a systematic review and meta-analysisJavier P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
Eur J Gastroenterol Hepatol 16:89-99. 2004....
[Role of biological markers in inflammatory bowel disease]Javier P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Espana
Gastroenterol Hepatol 30:117-29. 2007..Like calprotectin, fecal lactoferrin is also quantified by a simple and inexpensive ELISA method, although there is considerably less experience with this latter marker...
Meta-analysis: the efficacy of azathioprine and mercaptopurine in ulcerative colitisJ P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa, Madrid, Spain
Aliment Pharmacol Ther 30:126-37. 2009..Debate exists regarding to whether thiopurine therapy is as effective in ulcerative colitis (UC) as it is in Crohn's disease...
[Study of the validity of "rapid" serology in diagnosing Helicobacter pylori infection]J P Gisbert
Hospital de la Princesa Madrid España
Aten Primaria 30:501-6. 2002..To evaluate prospectively the validity of a <<rapid>> serology diagnosis method (using capillary blood) in our ambit, taking for reference a combination of standard diagnostic methods...
Basal and stimulated gastrin and pepsinogen levels after eradication of Helicobacter pylori: a 1-year follow-up studyJ P Gisbert
Department of Gastroenterology, Ramon y Cajal Hospital, University of Alcala de Henares, Madrid, Spain
Eur J Gastroenterol Hepatol 11:189-200. 1999..Finally, an evaluation was made of the variables influencing gastrin and PG concentration, with particular attention to H. pylori infection and histological lesions of gastric mucosa...
Review article: prevention and management of hepatitis B and C infection in patients with inflammatory bowel diseaseJ P Gisbert
Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigacion Sanitaria, Princesa IP, Madrid, Spain
Aliment Pharmacol Ther 33:619-33. 2011..Viral hepatitis is a very common infection...
Review article: common misconceptions in the management of Helicobacter pylori-associated gastric MALT-lymphomaJ P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain
Aliment Pharmacol Ther 34:1047-62. 2011..Helicobacter pylori infection is the main cause of gastric mucosa-associated lymphoid tissue (MALT) lymphoma...
Clinical trial evaluating amoxicillin and clarithromycin hydrogels (Chitosan-polyacrylic acid polyionic complex) for H. pylori eradicationJavier P Gisbert
Gastroenterology Unit, La Princesa University Hospital, Autonomous University, School of Pharmacy, Alcala de Henares University, Alcala de Henares, Spain
J Clin Gastroenterol 40:618-22. 2006..This could be achieved by allowing the drug to remain longer in the stomach using dried hydrogels. Our aim was to evaluate the efficacy of an H. pylori eradication regimen including both amoxicillin and clarithromycin hydrogels...
Proton pump inhibitors versus H2-antagonists: a meta-analysis of their efficacy in treating bleeding peptic ulcerJ P Gisbert
Department of Gastroenterology, University Hospital La Princesa, Madrid, Spain
Aliment Pharmacol Ther 15:917-26. 2001..To evaluate whether proton pump inhibitors are more effective than H2-antagonists (H2-A) for the treatment of bleeding peptic ulcer...
Helicobacter pylori infection, gastric metaplasia in the duodenum and the relationship with ulcer recurrenceJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Eur J Gastroenterol Hepatol 12:1295-8. 2000..pylori) infection and gastric metaplasia (GM) in the duodenum a large group of patients with duodenal ulcer was evaluated to determine whether these factors are related to the number of ulcer recurrences...
13C-urea breath test for the diagnosis of Helicobacter pylori infection: are basal samples necessary?J P Gisbert
Department of Gastroenterology, Hospital de la Princesa, Universidad Autonoma de Madrid, Spain
Eur J Gastroenterol Hepatol 12:1201-5. 2000..g. depending on diet). However, the superiority of this strategy has not been sufficiently demonstrated. The elimination of basal samples in the 13C-UBT protocol would have the advantages of higher simplicity and speed...
[Helicobacter pylori and digestive hemorrhage due to duodenal ulcer: the prevalence of the infection, the efficacy of 3 triple therapies and the role of eradication in preventing a hemorrhagic recurrence]J P Gisbert
Servicio de Gastroenterologia, Hospital Ramon y Cajal, Departamento de Medicina, Universidad de Alcala de Henares, Madrid
Med Clin (Barc) 112:161-5. 1999..To evaluate the efficacy on H. pylori eradication and on ulcer healing of three one-week triple therapies and to compare their efficacy with that of a dual therapy...
Helicobacter pylori eradication: proton pump inhibitor vs. ranitidine bismuth citrate plus two antibiotics for 1 week-a meta-analysis of efficacyJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Aliment Pharmacol Ther 14:1141-50. 2000..To compare the efficacy of proton pump inhibitor vs. ranitidine bismuth citrate (RBC) with two antibiotics for 1 week in Helicobacter pylori eradication...
["Rapid" serology for the diagnosis of Helicobacter pylori infection. Evaluation of its accuracy compared with a gold-standard and its concordance with "classic" serology]J P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid
Gastroenterol Hepatol 23:159-64. 2000....
Seven-day 'rescue' therapy after Helicobacter pylori treatment failure: omeprazole, bismuth, tetracycline and metronidazole vs. ranitidine bismuth citrate, tetracycline and metronidazoleJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Aliment Pharmacol Ther 13:1311-6. 1999..A 'rescue' therapy with a quadruple combination of O, bismuth (B), tetracycline (T) and metronidazole (M) has been recommended...
Re-treatment after Helicobacter pylori eradication failureJ P Gisbert
Department of Gastroenterology, Hospital Ramon y Cajal, Universidad de Alcala de Henares, Madrid, Spain
Eur J Gastroenterol Hepatol 11:1049-54. 1999..Therefore, our aim was to evaluate the appropriate attitude when eradication therapy fails...
Helicobacter pylori and gastroesophageal reflux disease: friends or foes?J P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
Hepatogastroenterology 46:1023-9. 1999..In conclusion, H. pylori and GERD seem to have, in any case, a "friendly" relationship, although it may be transformed into one of "hate" when PPIs enter the scene...
[Antral biopsy is sufficient to confirm Helicobacter pylori eradication with the "new" one-week long triple treatments]J P Gisbert
Hospital Ramon y Cajal, Departamento de Medicina, Universidad de Alcala de Henares, Madrid
Med Clin (Barc) 112:365-7. 1999..To evaluate whether antral biopsies are enough for confirming Helicobacter pylori eradication with the "new" one week triple therapies with omeprazole...
Are twelve days of omeprazole, amoxicillin and clarithromycin better than six days for treating H. pylori infection in peptic ulcer and in non-ulcer dyspepsia?J P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Hepatogastroenterology 48:1383-8. 2001....
Helicobacter pylori eradication therapy is more effective in peptic ulcer than in non-ulcer dyspepsiaJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Eur J Gastroenterol Hepatol 13:1303-7. 2001..To evaluate whether eradication therapy is more effective in peptic ulcer disease (PUD) than in non-ulcer dyspepsia (NUD)...
[Helicobacter pylori-related diseases: dyspepsia, ulcer and gastric cancer]Javier P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Espana
Gastroenterol Hepatol 31:18-28. 2008..The annual recurrence rate of H. pylori infection is approximately 3% in developed countries and is higher than 10% in developing countries...
Impact of gastroesophageal reflux disease on patients' daily lives: a European observational study in the primary care settingJavier P Gisbert
Department of Gastroenterology, Hospital Universitario de Princesa, Madrid, Spain, and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Spain
Health Qual Life Outcomes 7:60. 2009..We report the burden of GERD in a large population of patients managed in primary care, in terms of symptoms and impact on patients' daily lives...
[Individualized therapy with azathioprine or 6-mercaptopurine by monitoring thiopurine methyl-transferase (TPMT) activity]J P Gisbert
Servicio de Aparato Digestivo. Hospital Universitario de la Princesa. Madrid. Spain
Rev Clin Esp 202:555-62. 2002
[Prevalence of Helicobacter pylori infection in gastroesophageal reflux disease and Barretts esophagus]Javier P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
Med Clin (Barc) 119:217-23. 2002
Role of partner's infection in reinfection after Helicobacter pylori eradicationJavier P Gisbert
Department of Gastroenterology, Hospital de la Princesa, Universidad Autonoma de Madrid, Spain
Eur J Gastroenterol Hepatol 14:865-71. 2002..To evaluate whether the Helicobacter pylori status of the patient's spouse plays a role in reinfection after eradication success, and to assess the possibility of transmission of H. pylori among partners by using molecular methods...
Helicobacter pylori first-line treatment and rescue option containing levofloxacin in patients allergic to penicillinJ P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain
Dig Liver Dis 42:287-90. 2010..To assess the efficacy and tolerability of Helicobacter pylori first-line treatment (omeprazole-clarithromycin-metronidazole) and second-line rescue option (omeprazole-clarithromycin-levofloxacin) in patients allergic to penicillin...
Management of gastro-oesophageal reflux disease in primary care: a European observational studyJavier P Gisbert
Department of Gastroenterology, Hospital Universitario de la Princesa, C Diego de Leon 62, Madrid, Spain
Curr Med Res Opin 25:2777-84. 2009..To describe the management of gastro-oesophageal reflux disease (GERD) in primary care, as part of the RANGE (Retrospective ANalysis of GERD) study...
Review article: Helicobacter pylori "rescue" regimen when proton pump inhibitor-based triple therapies failJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Playa de Mojácar 29, Urb Bonanza, 28669 Boadilla del Monte, Madrid, Spain
Aliment Pharmacol Ther 16:1047-57. 2002..Recently, rifabutin-based rescue therapies have been shown to constitute an encouraging strategy for eradication failures, as they are effective against H. pylori strains resistant to antibiotics...
Impact of gastroesophageal reflux disease on work absenteeism, presenteeism and productivity in daily life: a European observational studyJavier P Gisbert
Department of Gastroenterology, Hospital Universitario de la Princesa, Madrid, Spain
Health Qual Life Outcomes 7:90. 2009..This subanalysis of RANGE determined the impact of GERD on productivity in work and daily life...
Sequential therapy for Helicobacter pylori eradication: a critical reviewJavier P Gisbert
Department of Gastroenterology, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain
J Clin Gastroenterol 44:313-25. 2010..Alternative treatment regimens for standard triple therapy are urgently needed...
Second-line rescue therapy of helicobacter pylori infectionJavier P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Madrid, Spain
Therap Adv Gastroenterol 2:331-56. 2009..Therefore, the attitude in H. pylori eradication therapy failure, even after two or more unsuccessful attempts, should be to fight and not to surrender...
Consultation rates and characteristics of gastro-oesophageal reflux disease in primary care: a European observational studyJavier P Gisbert
Department of Gastroenterology, Hospital Universitario de la Princesa, Madrid, Spain
Eur J Gen Pract 15:154-60. 2009..To report on the primary care consultation rates and clinical characteristics of patients with gastro-oesophageal reflux disease (GERD) as part of the RANGE (Retrospective ANalysis of GERD) observational study...
Adherence of gastroenterologists to European Crohn's and Colitis Organisation consensus on ulcerative colitis: a real-life survey in SpainJ P Gisbert
Departamento de Gastroenterologia, Hospital Universitario La Princesa and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas CIBEREHD, Spain
J Crohns Colitis 4:567-74. 2010..This knowledge would allow the local evaluation of the situation and the adoption of actions to reduce the existent clinical variability...
[Effects of Helicobacter pylori eradication on the recurrence of gastric ulcer during a 12-month follow up]F Bermejo
Servicio de Gastroenterologia, Hospital Ramon y Cajal, Madrid
Med Clin (Barc) 115:201-4. 2000..To study the influence of Helicobacter pylori eradication on the incidence of ulcer recurrence during 12 months of follow-up in gastric ulcer patients...
What is the optimal length of proton pump inhibitor-based triple therapies for H. pylori? A cost-effectiveness analysisX Calvet
Servei de Medicina, Corporacio Sanitaria Parc Tauli, Sabadell, Spain Servicio de Aparato Digestivo, Hospital de la Princesa, Madrid, Spain
Aliment Pharmacol Ther 15:1067-76. 2001..Triple therapy with a proton pump inhibitor, clarithromycin and amoxicillin is widely used for H. pylori infection. The appropriate length of treatment remains controversial...
Third-line rescue therapy with levofloxacin after two H. pylori treatment failuresJavier P Gisbert
Hospital de la Princesa, Madrid, Spain
Am J Gastroenterol 101:243-7. 2006..pylori eradication failures with key antibiotics such as amoxicillin, clarithromycin, metronidazole, and tetracycline...
Second-line rescue therapy with levofloxacin after H. pylori treatment failure: a Spanish multicenter study of 300 patientsJavier P Gisbert
Hospital de la Princesa, Madrid
Am J Gastroenterol 103:71-6. 2008..Our aim was to evaluate the efficacy and tolerability of a triple second-line levofloxacin-based regimen in patients with H. pylori eradication failure...
Clinical trial: clarithromycin vs. levofloxacin in first-line triple and sequential regimens for Helicobacter pylori eradicationJ Molina-Infante
Department of Gastroenterology, Hospital San Pedro de Alcantara, Caceres, Spain
Aliment Pharmacol Ther 31:1077-84. 2010..Helicobacter pylori eradication rates with standard triple therapy have declined to unacceptable levels...
High efficacy of ranitidine bismuth citrate, amoxicillin, clarithromycin and metronidazole twice daily for only five days in Helicobacter pylori EradicationJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Helicobacter 6:157-62. 2001..CONCLUSION: The combination of Rbc, amoxicillin, clarithromycin and metronidazole for only 5 days represents a promising therapy for H. pylori infection, due to its high efficacy, simple posology, low cost and excellent tolerance...
Diagnosis of Helicobacter pylori infection by stool antigen determination: a systematic reviewJ P Gisbert
Department of Gastroenterology University Hospital of La Princesa, Madrid, Spain
Am J Gastroenterol 96:2829-38. 2001..although the true diagnostic accuracy in this group of patients remains to be more fully assessed. Finally, the SA test seems to be a highly cost-effective method for the diagnosis of H. pylori infection...
Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based studyFrancesc Balaguer
Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBERehd, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
Clin Gastroenterol Hepatol 5:379-87. 2007....
The TETRA study: a prospective evaluation of Helicobacter pylori 'test-and-treat' strategy on 736 patients in clinical practiceJavier P Gisbert
Department of Gastroenterology, Hospital Universitario de la Princesa, Madrid, Spain
Helicobacter 9:28-38. 2004..No gastric or oesophageal cancer was diagnosed. CONCLUSION: This large prospective study shows that the test-and-treat strategy is effective and safe for management of dyspeptic patients in clinical practice...
Esomeprazole-based therapy in Helicobacter pylori eradication: any effect by increasing the dose of esomeprazole or prolonging the treatment?Javier P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
Am J Gastroenterol 100:1935-40. 2005..To study the efficacy of esomeprazole-based triple therapy in Helicobacter pylori eradication and to evaluate, by a randomized trial, the effect of increasing the dose of esomeprazole or prolonging the treatment...
Helicobacter pylori and bleeding peptic ulcer: what is the prevalence of the infection in patients with this complication?J P Gisbert
Dept of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Scand J Gastroenterol 38:2-9. 2003
Accuracy of Helicobacter pylori diagnostic tests in patients with bleeding peptic ulcer: a systematic review and meta-analysisJavier P Gisbert
Department of Gastroenterology, La Princesa University Hospital, , Madrid, Spain
Am J Gastroenterol 101:848-63. 2006..Stool antigen test is less accurate in UGIB. Although serology seems not to be influenced by UGIB, it cannot be recommended as the first diagnostic test for H. pylori infection in this setting...
Third-line rescue therapy with levofloxacin is more effective than rifabutin rescue regimen after two Helicobacter pylori treatment failuresJ P Gisbert
Department of Gastroenterology, La Princesa University Hospital, Universidad Autonoma, Madrid, Spain
Aliment Pharmacol Ther 24:1469-74. 2006..In patients with a first eradication failure, a second (rescue) therapy still fails in > 20% of cases...
[Treatment of stenosis due to Crohn's disease]J P Gisbert
Servicio de Aparato Digestivo. Hospital Universitario de la Princesa. Madrid. Spain
Gastroenterol Hepatol 25:560-9. 2002
Helicobacter pylori therapy: first-line options and rescue regimenJ P Gisbert
Department of Gastroenterology, University Hospital La Princesa, Madrid, Spain
Dig Dis 19:134-43. 2001....
Helicobacter pylori "test-and-scope" strategy for dyspeptic patients. Is it useful and safe?J P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Dig Liver Dis 33:539-45. 2001..To evaluate outcome of test-and-scope strategy using 13C-urea breath test, Helicobacter pylori IgG serology, and CagA serology...
[Questions and answers on the role of azathioprine and 6-mercaptopurine in the treatment of inflammatory bowel disease]J P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Spain
Gastroenterol Hepatol 25:401-15. 2002
Meta-analysis: Helicobacter pylori eradication therapy vs. antisecretory non-eradication therapy for the prevention of recurrent bleeding from peptic ulcerJ P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Spain
Aliment Pharmacol Ther 19:617-29. 2004..To perform a meta-analysis comparing the efficacy of Helicobacter pylori eradication therapy vs. antisecretory non-eradication therapy for the prevention of recurrent bleeding from peptic ulcer...
Review article: Helicobacter pylori infection and gastric outlet obstruction - prevalence of the infection and role of antimicrobial treatmentJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Aliment Pharmacol Ther 16:1203-8. 2002..pylori-positive stenosis, whereas dilation or surgery should be reserved for patients who do not respond to such medical therapy...
Transient elastography to assess hepatic fibrosis in primary biliary cirrhosisE Gómez-Domínguez
Service of Gastroenterology, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain
Aliment Pharmacol Ther 27:441-7. 2008..Liver stiffness measurements may have potential for detecting and monitoring hepatic fibrosis in chronic liver disease...
Gastric angiogenesis and Helicobacter pylori infectionI D Pousa
Service of Gastroenterology, Hospital Universitario de la Princesa, Madrid, Spain
Rev Esp Enferm Dig 98:527-41. 2006..In the case of gastric cancer, neoangiogenesis would enhance nutrient and oxygen supply to cancer cells, and thus tumor growth and metastatic spread...
Proton pump inhibitor, clarithromycin and either amoxycillin or nitroimidazole: a meta-analysis of eradication of Helicobacter pyloriJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Aliment Pharmacol Ther 14:1319-28. 2000..those using proton pump inhibitor, clarithromycin and a nitroimidazole (N) (PCN) for H. pylori eradication...
Evaluation of 3 different tests for the detection of stool antigens to confirm Helicobacter pylori eradication after treatment. A pilot studyJ P Gisbert
Servicio de Gastroenterologia, Hospital Universitario de la Princesa, Universidad Autonoma de Madrid, Madrid, Spain
Gastroenterol Hepatol 28:615-8. 2005..Eradication was confirmed with 13C-urea breath test 6-8 weeks later, when stool samples were analyzed by polyclonal (Premier-Platinum-HpSATM), monoclonal (Amplified-IDEIATM-HpStARTM), and rapid test (ImmunoCard-STAT-HpSATM)...
Systematic review: regression of lymphoproliferative disorders after treatment for hepatitis C infectionJ P Gisbert
Gastroenterology and Hepatology Service, La Princesa University Hospital, 28006 Madrid, Spain
Aliment Pharmacol Ther 21:653-62. 2005....
13C-urea breath test for the diagnosis of Helicobacter pylori infection before treatment: is citric acid necessary?J P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Dig Liver Dis 32:20-4. 2000..Thus, our aim was to compare 13C-urea breath test with and without citric acid solution, to evaluate whether 13C-urea breath test can also achieve favourable results when the test meal is omitted...
Value of quantitative serology for confirmation of Helicobacter pylori eradication: an 18-month follow-up studyJ P Gisbert
Department of Gastroenterology, Hospital de la Princesa, Universidad Autonoma, Madrid, Spain
Clin Infect Dis 30:976-80. 2000..5 months after antibiotic therapy is completed) can be used as a noninvasive, simple, and inexpensive method to confirm H. pylori eradication...
[Breath tests in the diagnosis of gastrointestinal diseases]J P Gisbert
Servicio de Aparato Digestivo, Hospital Universitario de la Princesa, Madrid, Espana
Gastroenterol Hepatol 28:407-16. 2005....
Review article: non-bismuth quadruple (concomitant) therapy for eradication of Helicobater pyloriJ P Gisbert
Department of Gastroenterology, Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria Princesa IP, and Centro de Investigación Biomédica en Red de enfermedades hepáticas y digestivas CIBERehd, Madrid, Spain
Aliment Pharmacol Ther 34:604-17. 2011..Traditional standard triple therapy for Helicobacter pylori infection (PPI-clarithromycin-amoxicillin) can easily be converted to non-bismuth quadruple (concomitant) therapy by the addition of a nitroimidazole twice daily...
Helicobacter pylori and bleeding duodenal ulcer: prevalence of the infection and role of non-steroidal anti-inflammatory drugsJ P Gisbert
Dept of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Scand J Gastroenterol 36:717-24. 2001..Our aim was to study the prevalence of H. pylori in bleeding duodenal ulcer (DU), with both invasive and non-invasive methods, and to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs)...
Helicobacter pylori and gastroesophageal reflux disease: lack of influence of infection on twenty-four-hour esophageal pH monitoring and endoscopic findingsJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
J Clin Gastroenterol 32:210-4. 2001..14 +/- 12 mmHg) among H. pylori-positive and -negative patients. H. pylori infection is not associated with gastroesophageal reflux disease, as evaluated endoscopically and with 24-hour esophageal pH monitoring...
Recurrence of Helicobacter pylori infection after several eradication therapies: long-term follow-up of 1000 patientsJ P Gisbert
Gastroenterology Units of La Princesa University Hospital, Madrid, Spain
Aliment Pharmacol Ther 23:713-9. 2006..To study the incidence of Helicobacter pylori recurrence, its chronological aspects, and the variables that might influence it...
First-line triple therapy with levofloxacin for Helicobacter pylori eradicationJ P Gisbert
Gastroenterology Unit, Hospital Universitario de la Princesa, Madrid, Spain
Aliment Pharmacol Ther 26:495-500. 2007..At present, the efficacy of proton pump inhibitor-clarithromycin-amoxicillin regimen is relatively low...
Review article: 13C-urea breath test in the diagnosis of Helicobacter pylori infection -- a critical reviewJ P Gisbert
Department of Gastroenterology, University Hospital of La Princesa, Madrid, Spain
Aliment Pharmacol Ther 20:1001-17. 2004....
