Jose Luis Garcia-Perez

Summary

Country: Spain

Publications

  1. pmc Epigenetic control of retrotransposon expression in human embryonic stem cells
    Angela Macia
    Andalusian Stem Cell Bank, Department of Molecular Embryology, Center for Biomedical Research, Avda Conocimiento s n, Armilla, Granada 18100, Spain
    Mol Cell Biol 31:300-16. 2011
  2. pmc Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells
    Jose L Garcia-Perez
    Department of Human Genetics, 1241 East Catherine Street, University of Michigan Medical School, Ann Arbor, Michigan 48109 5618, USA
    Nature 466:769-73. 2010
  3. pmc Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase
    Huira C Kopera
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109 5618, USA
    Proc Natl Acad Sci U S A 108:20345-50. 2011
  4. doi request reprint LINE-1 elements in structural variation and disease
    Christine R Beck
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 5618, USA
    Annu Rev Genomics Hum Genet 12:187-215. 2011
  5. ncbi request reprint Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres
    Tammy A Morrish
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 0618, USA
    Nature 446:208-12. 2007

Collaborators

Detail Information

Publications5

  1. pmc Epigenetic control of retrotransposon expression in human embryonic stem cells
    Angela Macia
    Andalusian Stem Cell Bank, Department of Molecular Embryology, Center for Biomedical Research, Avda Conocimiento s n, Armilla, Granada 18100, Spain
    Mol Cell Biol 31:300-16. 2011
    ....
  2. pmc Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells
    Jose L Garcia-Perez
    Department of Human Genetics, 1241 East Catherine Street, University of Michigan Medical School, Ann Arbor, Michigan 48109 5618, USA
    Nature 466:769-73. 2010
    ..Thus, our data indicate that ECs differ from many differentiated cells in their ability to silence reporter genes delivered by L1 retrotransposition...
  3. pmc Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase
    Huira C Kopera
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109 5618, USA
    Proc Natl Acad Sci U S A 108:20345-50. 2011
    ..Finally, we demonstrate that ORF1p is not strictly required for ENi retrotransposition at dysfunctional telomeres. Thus, these data further highlight similarities between the mechanism of ENi L1 retrotransposition and telomerase...
  4. doi request reprint LINE-1 elements in structural variation and disease
    Christine R Beck
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 5618, USA
    Annu Rev Genomics Hum Genet 12:187-215. 2011
    ..We next highlight how advances in DNA sequencing and genomic technologies have enabled the discovery of novel retrotransposons in individual genomes. Finally, we discuss how L1-mediated retrotransposition events impact human genomes...
  5. ncbi request reprint Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres
    Tammy A Morrish
    Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan 48109 0618, USA
    Nature 446:208-12. 2007
    ..Thus, we propose that EN(i) retrotransposition is an ancestral mechanism of RNA-mediated DNA repair associated with non-LTR retrotransposons that may have been used before the acquisition of an endonuclease domain...