J J Secades

Summary

Affiliation: Ferrer Internacional S.A
Country: Spain

Publications

  1. ncbi request reprint Citicoline: pharmacological and clinical review, 2010 update
    J J Secades
    Medical Department, Grupo Ferrer, SA, Barcelona, Spain
    Rev Neurol 52:S1-S62. 2011
  2. pmc Citicoline induces angiogenesis improving survival of vascular/human brain microvessel endothelial cells through pathways involving ERK1/2 and insulin receptor substrate-1
    Jerzy Krupinski
    Cerebrovascular Diseases, Department of Neurology, Hospital Universitari Mutua Terrassa, Terrassa, Barcelona, Spain
    Vasc Cell 4:20. 2012
  3. ncbi request reprint Probably role of citicoline in stroke rehabilitation: review of the literature
    Julio J Secades
    Medical Department, Grupo Ferrer, S A, 08028 Barcelona, Espana
    Rev Neurol 54:173-9. 2012
  4. ncbi request reprint Citicoline in intracerebral haemorrhage: a double-blind, randomized, placebo-controlled, multi-centre pilot study
    Julio J Secades
    Medical Department, Grupo Ferrer SA, Barcelona, Spain
    Cerebrovasc Dis 21:380-5. 2006
  5. ncbi request reprint Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion
    X A Alvarez
    EuroEspes Biomedical Research Center, A Coruna, Barcelona, Spain
    Methods Find Exp Clin Pharmacol 21:633-44. 1999
  6. ncbi request reprint CDP-choline reduces pro-caspase and cleaved caspase-3 expression, nuclear DNA fragmentation, and specific PARP-cleaved products of caspase activation following middle cerebral artery occlusion in the rat
    J Krupinski
    Unitat de Neuropatologia, Departament de Biologia Cellular i Anatomia Patologica, Universitat de Barcelona, Barcelona, Spain
    Neuropharmacology 42:846-54. 2002

Collaborators

  • Rafael Lozano
  • I Ferrer
  • Antoni Davalos
  • L Corzo
  • Jerzy Krupinski
  • J Krupinski
  • Mark Slevin
  • Anna Planas
  • Manal Abudawood
  • Eugen Bogdan Petcu
  • Sabine Matou-Nasri
  • Norma Rovira
  • Carlos Justicia
  • Donghui Liu
  • Marta Grau-Slevin
  • Raid Al-Baradie
  • X A Alvarez
  • M Barrachina
  • J Mercadal
  • P Perez
  • R Cacabelos
  • R Mouzo
  • M Laredo
  • R Zas
  • V Pichel
  • L Fernandez-Novoa
  • M Alcaraz

Detail Information

Publications6

  1. ncbi request reprint Citicoline: pharmacological and clinical review, 2010 update
    J J Secades
    Medical Department, Grupo Ferrer, SA, Barcelona, Spain
    Rev Neurol 52:S1-S62. 2011
    ..There are retrieved the most important experimental and clinical data in both indications...
  2. pmc Citicoline induces angiogenesis improving survival of vascular/human brain microvessel endothelial cells through pathways involving ERK1/2 and insulin receptor substrate-1
    Jerzy Krupinski
    Cerebrovascular Diseases, Department of Neurology, Hospital Universitari Mutua Terrassa, Terrassa, Barcelona, Spain
    Vasc Cell 4:20. 2012
    ..abstract:..
  3. ncbi request reprint Probably role of citicoline in stroke rehabilitation: review of the literature
    Julio J Secades
    Medical Department, Grupo Ferrer, S A, 08028 Barcelona, Espana
    Rev Neurol 54:173-9. 2012
    ..In this context, the role of citicoline in the rehabilitation of patients with stroke is reviewed...
  4. ncbi request reprint Citicoline in intracerebral haemorrhage: a double-blind, randomized, placebo-controlled, multi-centre pilot study
    Julio J Secades
    Medical Department, Grupo Ferrer SA, Barcelona, Spain
    Cerebrovasc Dis 21:380-5. 2006
    ..Citicoline is a neuroprotectant drug with some beneficial effects in human ischaemic stroke and with an excellent safety profile. We decided to carry out a pilot study to test its safety and efficacy in human intracerebral haemorrhaging...
  5. ncbi request reprint Double-blind placebo-controlled study with citicoline in APOE genotyped Alzheimer's disease patients. Effects on cognitive performance, brain bioelectrical activity and cerebral perfusion
    X A Alvarez
    EuroEspes Biomedical Research Center, A Coruna, Barcelona, Spain
    Methods Find Exp Clin Pharmacol 21:633-44. 1999
    ....
  6. ncbi request reprint CDP-choline reduces pro-caspase and cleaved caspase-3 expression, nuclear DNA fragmentation, and specific PARP-cleaved products of caspase activation following middle cerebral artery occlusion in the rat
    J Krupinski
    Unitat de Neuropatologia, Departament de Biologia Cellular i Anatomia Patologica, Universitat de Barcelona, Barcelona, Spain
    Neuropharmacology 42:846-54. 2002
    ..The expression of caspase-cleaved products of PARP (PARP 89 kDa) was reduced in citicoline-treated ischaemic rats. These results show that citicoline inhibits the expression of proteins involved in apoptosis following MCAO...