Javier Fernandez

Summary

Country: Spain

Publications

  1. ncbi Management of bacterial infections in cirrhosis
    Javier Fernandez
    Liver Unit, IMDiM, Hospital Clinic, Universidad de Barcelona, IDIBAPS and Ciberehd, Barcelona, Spain
    J Hepatol 56:S1-12. 2012
  2. ncbi Prevalence and risk factors of infections by multiresistant bacteria in cirrhosis: a prospective study
    Javier Fernandez
    Liver Unit, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Hepatology 55:1551-61. 2012
  3. ncbi [Adrenal insufficiency in cirrhosis]
    Javier Fernandez
    IMDiM, IDIBAPS, Hospital Clinic, Universidad de Barcelona, CIBERehd, Barcelona, Espana
    Gastroenterol Hepatol 31:606-11. 2008
  4. ncbi Effect of intravenous albumin on systemic and hepatic hemodynamics and vasoactive neurohormonal systems in patients with cirrhosis and spontaneous bacterial peritonitis
    Javier Fernandez
    Liver Unit, IMD, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
    J Hepatol 41:384-90. 2004
  5. ncbi A randomized unblinded pilot study comparing albumin versus hydroxyethyl starch in spontaneous bacterial peritonitis
    Javier Fernandez
    Liver Unit, IMDM and IDIBAPS, Hospital Clinic, University of Barcelona, Spain
    Hepatology 42:627-34. 2005
  6. ncbi Adrenal insufficiency in patients with cirrhosis and septic shock: Effect of treatment with hydrocortisone on survival
    Javier Fernandez
    Liver Unit, Department of Surgery and Centro de Investigaciones Biomédicas Esther Koplowitz, IMDiM, IDIBAPS, Hospital Clinic, University of Barcelona, Spain
    Hepatology 44:1288-95. 2006
  7. ncbi Albumin for bacterial infections other than spontaneous bacterial peritonitis in cirrhosis. A randomized, controlled study
    Monica Guevara
    Liver Unit, Hospital Clinic, University of Barcelona, Barcelona, Catalunya, Spain
    J Hepatol 57:759-65. 2012
  8. ncbi Renal failure and hyponatremia in patients with cirrhosis and skin and soft tissue infection. A retrospective study
    Gustavo Pereira
    University of Barcelona, Barcelona, Spain
    J Hepatol 56:1040-6. 2012
  9. ncbi Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage
    Javier Fernandez
    IMDM and IDIBAPS, Liver Unit, Hospital Clinic, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain
    Gastroenterology 131:1049-56; quiz 1285. 2006
  10. ncbi Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis
    Javier Fernandez
    Liver Unit, IMD, and Department of Microbiology and IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Hepatology 35:140-8. 2002

Collaborators

Detail Information

Publications20

  1. ncbi Management of bacterial infections in cirrhosis
    Javier Fernandez
    Liver Unit, IMDiM, Hospital Clinic, Universidad de Barcelona, IDIBAPS and Ciberehd, Barcelona, Spain
    J Hepatol 56:S1-12. 2012
    ..This review is focused on the currently recommended diagnostic, therapeutic and prophylactic strategies for bacterial infections in the cirrhotic population...
  2. ncbi Prevalence and risk factors of infections by multiresistant bacteria in cirrhosis: a prospective study
    Javier Fernandez
    Liver Unit, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Hepatology 55:1551-61. 2012
    ..New antibiotic strategies tailored according to the local epidemiological patterns are needed for the empirical treatment of nosocomial infections in cirrhosis...
  3. ncbi [Adrenal insufficiency in cirrhosis]
    Javier Fernandez
    IMDiM, IDIBAPS, Hospital Clinic, Universidad de Barcelona, CIBERehd, Barcelona, Espana
    Gastroenterol Hepatol 31:606-11. 2008
    ..This chapter summarizes the main aspects of the physiopathology, diagnosis and treatment of this entity in patients with acute or chronic liver disease...
  4. ncbi Effect of intravenous albumin on systemic and hepatic hemodynamics and vasoactive neurohormonal systems in patients with cirrhosis and spontaneous bacterial peritonitis
    Javier Fernandez
    Liver Unit, IMD, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
    J Hepatol 41:384-90. 2004
    ..Albumin administration prevents renal failure and improves survival in spontaneous bacterial peritonitis. This study characterizes the mechanisms of action of albumin in this condition...
  5. ncbi A randomized unblinded pilot study comparing albumin versus hydroxyethyl starch in spontaneous bacterial peritonitis
    Javier Fernandez
    Liver Unit, IMDM and IDIBAPS, Hospital Clinic, University of Barcelona, Spain
    Hepatology 42:627-34. 2005
    ..This effect is due not only to volume expansion but also to an action on the peripheral arterial circulation...
  6. ncbi Adrenal insufficiency in patients with cirrhosis and septic shock: Effect of treatment with hydrocortisone on survival
    Javier Fernandez
    Liver Unit, Department of Surgery and Centro de Investigaciones Biomédicas Esther Koplowitz, IMDiM, IDIBAPS, Hospital Clinic, University of Barcelona, Spain
    Hepatology 44:1288-95. 2006
    ..Hydrocortisone administration in these patients is associated with a high frequency of shock resolution and high survival rate...
  7. ncbi Albumin for bacterial infections other than spontaneous bacterial peritonitis in cirrhosis. A randomized, controlled study
    Monica Guevara
    Liver Unit, Hospital Clinic, University of Barcelona, Barcelona, Catalunya, Spain
    J Hepatol 57:759-65. 2012
    ..Whether albumin has similar beneficial effects in patients with infections other than SBP is unknown...
  8. ncbi Renal failure and hyponatremia in patients with cirrhosis and skin and soft tissue infection. A retrospective study
    Gustavo Pereira
    University of Barcelona, Barcelona, Spain
    J Hepatol 56:1040-6. 2012
    ..This study aimed at assessing the characteristics, occurrence of renal failure, and outcome of cirrhotic patients with skin and soft tissue infection...
  9. ncbi Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage
    Javier Fernandez
    IMDM and IDIBAPS, Liver Unit, Hospital Clinic, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain
    Gastroenterology 131:1049-56; quiz 1285. 2006
    ..This randomized controlled trial was aimed to compare oral norfloxacin vs intravenous ceftriaxone in the prophylaxis of bacterial infection in cirrhotic patients with gastrointestinal bleeding...
  10. ncbi Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis
    Javier Fernandez
    Liver Unit, IMD, and Department of Microbiology and IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Hepatology 35:140-8. 2002
    ..Quinolone-resistant spontaneous bacterial peritonitis constitutes an emergent problem in patients on long-term norfloxacin prophylaxis, with trimethoprim-sulfamethoxazole not being a valid alternative...
  11. ncbi Prognostic importance of the cause of renal failure in patients with cirrhosis
    Marta Martín-Llahí
    Liver Unit, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Gastroenterology 140:488-496.e4. 2011
    ..The prognostic value of the different causes of renal failure in cirrhosis is not well established. This study investigated the predictive value of the cause of renal failure in cirrhosis...
  12. ncbi Urinary neutrophil gelatinase-associated lipocalin as biomarker in the differential diagnosis of impairment of kidney function in cirrhosis
    Claudia Fagundes
    Liver Unit, Hospital Clinic, University of Barcelona, Barcelona, Catalunya, Spain
    J Hepatol 57:267-73. 2012
    ..We aimed at assessing the usefulness of neutrophil gelatinase-associated lipocalin (NGAL), a biomarker of tubular damage, in the differential diagnosis of impairment of kidney function in cirrhosis...
  13. ncbi Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis
    Javier Fernandez
    Liver Unit, Hospital Clinic Barcelona, Barcelona, Spain
    Gastroenterology 133:818-24. 2007
    ..Norfloxacin is highly effective in preventing spontaneous bacterial peritonitis recurrence in cirrhosis, but its role in the primary prevention of this complication is uncertain...
  14. ncbi Failure of Lactobacillus spp. to prevent bacterial translocation in a rat model of experimental cirrhosis
    Tilman Martin Bauer
    Liver Unit, Institut Malalties Digestives, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    J Hepatol 36:501-6. 2002
    ..We investigated whether an alternative strategy with Lactobacillus prevents bacterial translocation and ascitic fluid infection in cirrhotic rats...
  15. ncbi Management of critically-ill cirrhotic patients
    Pere Gines
    Liver Unit, IMDiM, Hospital Clinic Barcelona, University of Barcelona and IDIBAPS and Ciberehd, Barcelona, Spain
    J Hepatol 56:S13-24. 2012
    ..This review will focus on the diagnostic approach and treatment strategies currently recommended in the critical care management of patients with cirrhosis...
  16. ncbi Hyponatremia in patients treated with terlipressin for severe gastrointestinal bleeding due to portal hypertension
    Elsa Solá
    Liver Unit, Hospital Clinic, University of Barcelona, Barcelona, Catalunya, Spain
    Hepatology 52:1783-90. 2010
    ..It develops rapidly after start of therapy, may be severe in some patients and is associated with neurological complications, and is usually reversible after terlipressin withdrawal...
  17. ncbi Pathogenesis and treatment of hepatorenal syndrome
    Vicente Arroyo
    Liver Unit, Institute of Digestive and Metabolic Diseases, CIBERehd, Hospital Clinic, University of Barcelona, Spain
    Semin Liver Dis 28:81-95. 2008
    ..However, effective treatments of HRS (vasoconstrictors associated with intravenous albumin, transjugular intrahepatic portacaval shunt, albumin dialysis) that can improve survival have recently been introduced...
  18. ncbi Management of hepatorenal syndrome in patients with cirrhosis
    Vicente Arroyo
    Liver Unit, Hospital Clinic Barcelona, University of Barcelona, Villarroel 170, Barcelona, Catalonia 08036, Spain
    Nat Rev Nephrol 7:517-26. 2011
    ..Albumin dialysis is a potentially effective treatment for type 1 HRS still under investigation. Patients with type 2 HRS are treated with repeated large-volume paracentesis or TIPS...
  19. ncbi Pathophysiological basis of albumin use in cirrhosis
    Vicente Arroyo
    Liver Unit, Institut de Malalties Digestives i Metaboliques, Hospital Clinic and Institut d Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Ann Hepatol 10:S6-14. 2011
    ..Impairment of albumin function is one of the most characteristic traits of cirrhosis. Administration of exogenous albumin could be beneficial because of its positive effects on microcirculation...
  20. ncbi Increased apoptosis dependent on caspase-3 activity in polymorphonuclear leukocytes from patients with cirrhosis and ascites
    Maria Jose Ramirez
    Liver Unit, Hospital Clinic Universitari, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    J Hepatol 41:44-8. 2004
    ..The aim of the current study was to investigate whether the presence of increased PMN apoptosis could also contribute to the appearance of neutropenia in these patients...