Ramon Estruch

Summary

Country: Spain

Publications

  1. ncbi Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial
    Ramon Estruch
    Institut d Investigacions Biomèdiques August Pi Sunyer, Municipal Institut for Medical Research, University of Barcelona, and Catalan Institute of Health, Barcelona, Spain
    Ann Intern Med 145:1-11. 2006
  2. ncbi Anti-inflammatory effects of the Mediterranean diet: the experience of the PREDIMED study
    Ramon Estruch
    Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Spain
    Proc Nutr Soc 69:333-40. 2010
  3. ncbi Effects of wine, alcohol and polyphenols on cardiovascular disease risk factors: evidences from human studies
    Gemma Chiva-Blanch
    Corresponding author Department of Internal Medicine, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Alcohol Alcohol 48:270-7. 2013
  4. ncbi Primary prevention of cardiovascular disease with a Mediterranean diet
    Ramon Estruch
    Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain
    N Engl J Med 368:1279-90. 2013
  5. ncbi Moderate consumption of red wine, but not gin, decreases erythrocyte superoxide dismutase activity: a randomised cross-over trial
    R Estruch
    Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Nutr Metab Cardiovasc Dis 21:46-53. 2011
  6. ncbi Effects of dietary fibre intake on risk factors for cardiovascular disease in subjects at high risk
    R Estruch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomèdiques August Pi Sunyer, Barcelona, Spain
    J Epidemiol Community Health 63:582-8. 2009
  7. ncbi High urinary levels of resveratrol metabolites are associated with a reduction in the prevalence of cardiovascular risk factors in high-risk patients
    Raul Zamora-Ros
    Nutrition and Food Science Department, XaRTA INSA, Pharmacy School, University of Barcelona, Spain
    Pharmacol Res 65:615-20. 2012
  8. ncbi Myocardial antioxidant status in chronic alcoholism
    Francesc Fatjó
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Alcohol Clin Exp Res 29:864-70. 2005
  9. ncbi Effect of cocoa powder on the modulation of inflammatory biomarkers in patients at high risk of cardiovascular disease
    Maria Monagas
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Am J Clin Nutr 90:1144-50. 2009
  10. ncbi Down-regulation of adhesion molecules and other inflammatory biomarkers after moderate wine consumption in healthy women: a randomized trial
    Emilio Sacanella
    Department of Internal Medicine, Hospital Clinic, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Am J Clin Nutr 86:1463-9. 2007

Collaborators

Detail Information

Publications59

  1. ncbi Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial
    Ramon Estruch
    Institut d Investigacions Biomèdiques August Pi Sunyer, Municipal Institut for Medical Research, University of Barcelona, and Catalan Institute of Health, Barcelona, Spain
    Ann Intern Med 145:1-11. 2006
    ..The Mediterranean diet has been shown to have beneficial effects on cardiovascular risk factors...
  2. ncbi Anti-inflammatory effects of the Mediterranean diet: the experience of the PREDIMED study
    Ramon Estruch
    Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Spain
    Proc Nutr Soc 69:333-40. 2010
    ..These results support the recommendation of the Med-Diet as a useful tool against CVD...
  3. ncbi Effects of wine, alcohol and polyphenols on cardiovascular disease risk factors: evidences from human studies
    Gemma Chiva-Blanch
    Corresponding author Department of Internal Medicine, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Alcohol Alcohol 48:270-7. 2013
    ..However, caution should be taken when making recommendations related to alcohol consumption...
  4. ncbi Primary prevention of cardiovascular disease with a Mediterranean diet
    Ramon Estruch
    Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain
    N Engl J Med 368:1279-90. 2013
    ..We conducted a randomized trial of this diet pattern for the primary prevention of cardiovascular events...
  5. ncbi Moderate consumption of red wine, but not gin, decreases erythrocyte superoxide dismutase activity: a randomised cross-over trial
    R Estruch
    Department of Internal Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
    Nutr Metab Cardiovasc Dis 21:46-53. 2011
    ....
  6. ncbi Effects of dietary fibre intake on risk factors for cardiovascular disease in subjects at high risk
    R Estruch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomèdiques August Pi Sunyer, Barcelona, Spain
    J Epidemiol Community Health 63:582-8. 2009
    ..Thus, the effects of changes in dietary fibre intake on cardiovascular risk factors were assessed over 3 months in free-living high-risk subjects...
  7. ncbi High urinary levels of resveratrol metabolites are associated with a reduction in the prevalence of cardiovascular risk factors in high-risk patients
    Raul Zamora-Ros
    Nutrition and Food Science Department, XaRTA INSA, Pharmacy School, University of Barcelona, Spain
    Pharmacol Res 65:615-20. 2012
    ....
  8. ncbi Myocardial antioxidant status in chronic alcoholism
    Francesc Fatjó
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Alcohol Clin Exp Res 29:864-70. 2005
    ..The pathogenesis is multifactorial, with the antioxidant imbalance of cardiac muscle being a potential factor. The current study evaluates myocardial antioxidant status in ethanol consumers and its relation to cardiac damage...
  9. ncbi Effect of cocoa powder on the modulation of inflammatory biomarkers in patients at high risk of cardiovascular disease
    Maria Monagas
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Am J Clin Nutr 90:1144-50. 2009
    ..Because atherosclerosis is considered a low-grade inflammatory disease, some feeding trials have analyzed the effects of cocoa (an important source of flavonoids) on inflammatory biomarkers, but the results have been controversial...
  10. ncbi Down-regulation of adhesion molecules and other inflammatory biomarkers after moderate wine consumption in healthy women: a randomized trial
    Emilio Sacanella
    Department of Internal Medicine, Hospital Clinic, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Am J Clin Nutr 86:1463-9. 2007
    ..The mechanism for this beneficial effect might be reduced inflammatory responses, as suggested by prospective studies and small clinical trials in men. No studies have evaluated the antiinflammatory effects of wine in women...
  11. ncbi Inhibition of circulating immune cell activation: a molecular antiinflammatory effect of the Mediterranean diet
    Mari Pau Mena
    Department of Internal Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Instituto de Salud Carlos III, Spain
    Am J Clin Nutr 89:248-56. 2009
    ..Adherence to the Mediterranean diet (Med-Diet) is associated with a reduced risk of cardiovascular disease (CVD). However, the molecular mechanisms involved are not fully understood...
  12. ncbi Decreased tumor necrosis factor-induced adhesion of human monocytes to endothelial cells after moderate alcohol consumption
    Eva Badia
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Spain
    Am J Clin Nutr 80:225-30. 2004
    ..Moderate alcohol consumption protects against ischemic heart disease, possibly through an antiinflammatory effect. However, little is known about the mechanisms by which alcohol may interfere in the development of atherosclerosis...
  13. ncbi The Mediterranean diet pattern and its main components are associated with lower plasma concentrations of tumor necrosis factor receptor 60 in patients at high risk for cardiovascular disease
    Mireia Urpi-Sarda
    Department of Internal Medicine, University of Barcelona, Barcelona, Spain
    J Nutr 142:1019-25. 2012
    ..01). This study suggests that a MD reduces TNFR concentrations in patients at high cardiovascular risk...
  14. ncbi Virgin olive oil and nuts as key foods of the Mediterranean diet effects on inflammatory biomakers related to atherosclerosis
    Mireia Urpi-Sarda
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, University of Barcelona, C Villarroel, 170, 08036 Barcelona, Spain
    Pharmacol Res 65:577-83. 2012
    ..02). In conclusion, Med-Diet exerts an anti-inflammatory effect on cardiovascular system since it down-regulates cellular and circulating inflammatory biomarkers related to atherogenesis in subjects at high cardiovascular risk...
  15. ncbi Dealcoholized red wine decreases systolic and diastolic blood pressure and increases plasma nitric oxide: short communication
    Gemma Chiva-Blanch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Circ Res 111:1065-8. 2012
    ..Experimental studies have shown a potential blood pressure (BP) lowering effect of red wine polyphenols, whereas the effects of ethanol and polyphenols on BP in humans are not yet clear...
  16. ncbi Alcohol consumption is associated with high concentrations of urinary hydroxytyrosol
    Helmut Schroder
    CIBER Fisiopatología Obesidad y Nutrición and Biochemistry and Molecular Biology, Instituto de Salud Carlos III, Santiago de Compostela, Spain
    Am J Clin Nutr 90:1329-35. 2009
    ..We hypothesized that the alcohol present in wine could promote endogenous hydroxytyrosol generation...
  17. ncbi Hypertensive status and lipoprotein oxidation in an elderly population at high cardiovascular risk
    Monica Guxens
    Cardiovascular Risk and Nutrition Research Unit, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Am J Hypertens 22:68-73. 2009
    ..Our aim was to assess the relationship between the degree of in vivo low-density lipoprotein (oxLDL) oxidation and the hypertensive status in a elderly population at high cardiovascular risk...
  18. ncbi The effects of milk as a food matrix for polyphenols on the excretion profile of cocoa (-)-epicatechin metabolites in healthy human subjects
    Elena Roura
    Department of Nutrition and Food Science CeRTA, University of Barcelona, Av Joan XXIII s n, Barcelona 08028, Spain
    Br J Nutr 100:846-51. 2008
    ..Thus, more studies are needed to evaluate the effect of these different metabolite profiles on the body...
  19. ncbi Differential effects of polyphenols and alcohol of red wine on the expression of adhesion molecules and inflammatory cytokines related to atherosclerosis: a randomized clinical trial
    Gemma Chiva-Blanch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, Barcelona, Spain
    Am J Clin Nutr 95:326-34. 2012
    ..Few clinical studies have focused on the alcohol-independent cardiovascular effects of the phenolic compounds of red wine (RW)...
  20. ncbi Effect of Mediterranean diet on the expression of pro-atherogenic genes in a population at high cardiovascular risk
    Vicenta Llorente-Cortes
    Cardiovascular Research Center, CSIC ICCC, Hospital Sant Pau, Barcelona, Spain
    Atherosclerosis 208:442-50. 2010
    ..Dietary intervention can thus actively modulate the expression of pro-atherothrombotic genes even in a high-risk population...
  21. ncbi A 14-item Mediterranean diet assessment tool and obesity indexes among high-risk subjects: the PREDIMED trial
    Miguel Angel Martinez-Gonzalez
    Prevención con Dieta Mediterránea Network RD 06 0045, Instituto de Salud Carlos III, Spanish Government, Madrid, Spain
    PLoS ONE 7:e43134. 2012
    ..We examined these associations using a 14-item tool of adherence to the Mediterranean diet as exposure and body mass index, waist circumference and waist-to-height ratio (WHtR) as outcomes...
  22. ncbi Wine, beer, alcohol and polyphenols on cardiovascular disease and cancer
    Sara Arranz
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Barcelona, 08036, Spain
    Nutrients 4:759-81. 2012
    ..This review summarizes the main protective effects on the cardiovascular system and cancer resulting from moderate wine and beer intake due mainly to their common components, alcohol and polyphenols...
  23. ncbi (1)H-NMR-based metabolomic analysis of the effect of moderate wine consumption on subjects with cardiovascular risk factors
    Rosa Vázquez-Fresno
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy Faculty, University of Barcelona, Barcelona, Spain
    Electrophoresis 33:2345-54. 2012
    ..The results show the capacity of this approach to obtain a comprehensive metabolome picture including food metabolome and endogenous biomarkers of moderate wine intake...
  24. ncbi Evidence of apoptosis in chronic alcoholic skeletal myopathy
    Joaquim Fernández-Solà
    Department of Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Spain
    Hum Pathol 34:1247-52. 2003
    ..However, the specific pathogenic mechanism of apoptosis in chronic skeletal myopathy in alcoholics remains to be elucidated...
  25. ncbi Polyphenol-rich foods in the Mediterranean diet are associated with better cognitive function in elderly subjects at high cardiovascular risk
    Cinta Valls-Pedret
    Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    J Alzheimers Dis 29:773-82. 2012
    ..The results reinforce the notion that Mediterranean diet components might counteract age-related cognitive decline...
  26. ncbi Inflammatory markers of atherosclerosis are decreased after moderate consumption of cava (sparkling wine) in men with low cardiovascular risk
    Mónica Vázquez Agell
    Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona 08036, Spain
    J Nutr 137:2279-84. 2007
    ..05). In conclusion, both cava and gin showed antiinflammatory properties; however, cava had a greater protective effect, probably due its polyphenol content...
  27. ncbi Resveratrol metabolites in urine as a biomarker of wine intake in free-living subjects: The PREDIMED Study
    Raul Zamora-Ros
    Nutrition and Food Science Department XaRTA, INSA, Pharmacy School, University of Barcelona, 08028 Barcelona, Spain
    Free Radic Biol Med 46:1562-6. 2009
    ..This biomarker would provide an additional tool for investigating more precisely the relationship between wine consumption and health benefits...
  28. ncbi Targeted metabolic profiling of phenolics in urine and plasma after regular consumption of cocoa by liquid chromatography-tandem mass spectrometry
    Mireia Urpi-Sarda
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy Faculty, University of Barcelona, 08028 Barcelona, Spain
    J Chromatogr A 1216:7258-67. 2009
    ..The results found herein indicate that 5-(3',4'-dihydroxyphenyl)-gamma-valerolactone and hydroxyphenylacetic acids could be good biomarkers of the regular consumption of cocoa and therefore, of flavanol-rich foods...
  29. ncbi Evaluation of myocyte proliferation in alcoholic cardiomyopathy: telomerase enzyme activity (TERT) compared with Ki-67 expression
    Meritxell Lluis
    Alcohol Research Unit, Department of Internal Medicine, Institut d Investigació August Pi i Sunyer, Hospital Clinic, University of Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Alcohol Alcohol 46:534-41. 2011
    ..We evaluated myocyte proliferation response in the heart of chronic alcoholic donors with telomerase activity (telomerase reverse transcriptase (TERT)) compared with Ki-67 nuclear expression...
  30. ncbi Milk does not affect the bioavailability of cocoa powder flavonoid in healthy human
    Elena Roura
    Department of Nutrition and Food Science CeRTA, University of Barcelona, Barcelona, Spain
    Ann Nutr Metab 51:493-8. 2007
    ..The food matrix is one the factors than can affect their bioavailability, but previous studies have concluded rather contradictory results about the effect of milk on the bioavailability of polyphenols...
  31. ncbi Gut and microbial resveratrol metabolite profiling after moderate long-term consumption of red wine versus dealcoholized red wine in humans by an optimized ultra-high-pressure liquid chromatography tandem mass spectrometry method
    Maria Rotchés-Ribalta
    Nutrition and Food Science Department, XaRTA INSA, Pharmacy Faculty, University of Barcelona, Av Joan XXIII, S N, 08028 Barcelona, Spain
    J Chromatogr A 1265:105-13. 2012
    ..In this sense, having a more precise concentration value of all the resveratrol metabolites in target tissues would finally lead to a better interpretation of the obtained results...
  32. ncbi Effects of red wine polyphenols and alcohol on glucose metabolism and the lipid profile: a randomized clinical trial
    Gemma Chiva-Blanch
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Clin Nutr 32:200-6. 2013
    ..The aim of the present study was to compare the effects of moderate consumption of red wine, dealcoholized red wine, and gin on glucose metabolism and the lipid profile...
  33. ncbi Evidence of apoptosis in alcoholic cardiomyopathy
    Joaquim Fernández-Solà
    Department of Internal Medicine, Hospital Clinic, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Spain
    Hum Pathol 37:1100-10. 2006
    ..Proapoptotic mechanisms are activated in alcoholic patients without heart damage...
  34. ncbi Serum sterol responses to increasing plant sterol intake from natural foods in the Mediterranean diet
    Veronica Escurriol
    Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomèdiques Ausgust Pi Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
    Eur J Nutr 48:373-82. 2009
    ..Phytosterols in natural foods are thought to inhibit cholesterol absorption. The Mediterranean diet is rich in phytosterol-containing plant foods...
  35. ncbi Determination of resveratrol and piceid in beer matrices by solid-phase extraction and liquid chromatography-tandem mass spectrometry
    Gemma Chiva-Blanch
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy Faculty, University of Barcelona, Av Joan XXIII s n, 08028 Barcelona, Spain
    J Chromatogr A 1218:698-705. 2011
    ..Overall, beer is one of the products with the lowest levels of total resveratrol (μg/L), and despite its high consumption it should not be considered as a representative source of resveratrol...
  36. ncbi Determinants of the omega-3 index in a Mediterranean population at increased risk for CHD
    Aleix Sala-Vila
    Lipid Clinic, Endocrinology and Nutrition Service, Institut d Investigacions Biomèdiques August Pi Sunyer, Unitat de Lípids, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Br J Nutr 106:425-31. 2011
    ..Nevertheless, the high omega-3 index could at least partially explain the paradox of low rates of fatal CHD in Spain despite a high background prevalence of cardiovascular risk factors...
  37. ncbi Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets
    Maria Rotchés-Ribalta
    Nutrition and Food Science Department, XaRTA INSA, Pharmacy Faculty, University of Barcelona, Av Joan XXIII, S N, Barcelona, Spain
    Pharmacol Res 66:375-82. 2012
    ..1-3.6-fold higher urinary concentrations of microbial metabolites were observed after GE intervention at 12-24h urinary fraction. Therefore, supplement intake could be also a way to bring resveratrol benefits to human health...
  38. ncbi Rapid Folin-Ciocalteu method using microtiter 96-well plate cartridges for solid phase extraction to assess urinary total phenolic compounds, as a biomarker of total polyphenols intake
    Alexander Medina-Remón
    Nutrition and Food Science Department, XaRTA, INSA Pharmacy School, University of Barcelona, Av Joan XXIII s n, 08028 Barcelona, Spain
    Anal Chim Acta 634:54-60. 2009
    ..The method is fast and simple and it allows analysis of a large number of samples at the same time...
  39. ncbi Effect of a traditional Mediterranean diet on lipoprotein oxidation: a randomized controlled trial
    Montserrat Fito
    Lipids and Cardiovascular Epidemiology Unit, Institut Municipal d Investigacio Medica, IMIM Hospital del Mar, Barcelona, Spain
    Arch Intern Med 167:1195-203. 2007
    ..Despite the richness in antioxidants of the Mediterranean diet, to our knowledge, no randomized controlled trials have assessed its effect on in vivo lipoprotein oxidation...
  40. ncbi Total polyphenol intake estimated by a modified Folin-Ciocalteu assay of urine
    Elena Roura
    Department of Nutrition, , IDIBAPS, University of Barcelona, Barcelona, Spain
    Clin Chem 52:749-52. 2006
    ....
  41. ncbi Polyphenols excreted in urine as biomarkers of total polyphenol intake
    Alexander Medina-Remón
    Nutrition and Food Science Department, XaRTA, Instituto de Investigaciónen Nutrición y Seguridad Alimentaria, Pharmacy School, University of Barcelona, Barcelona, Spain
    Bioanalysis 4:2705-13. 2012
    ..A precise estimation of polyphenol consumption requires blood or urine sample biomarkers, although their association is usually highly complex...
  42. ncbi Effect of milk on the urinary excretion of microbial phenolic acids after cocoa powder consumption in humans
    Mireia Urpi-Sarda
    Nutrition and Food Science Department, XaRTA, INSA, Pharmacy Faculty, University of Barcelona, Barcelona, Spain
    J Agric Food Chem 58:4706-11. 2010
    ..In conclusion, milk partially affects the formation of microbial phenolic acids derived from the colonic degradation of procyanidins and other compounds present in cocoa powder...
  43. ncbi Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells
    Maria Monagas
    Department of Internal Medicine, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, Hospital Clinic, Universitat de Barcelona, 08036 Barcelona, Spain
    Br J Nutr 102:201-6. 2009
    ....
  44. ncbi Different effects of red wine and gin consumption on inflammatory biomarkers of atherosclerosis: a prospective randomized crossover trial. Effects of wine on inflammatory markers
    Ramon Estruch
    Department of Internal Medicine, Hospital Clinic, , University of Barcelona, Barcelona, Spain
    Atherosclerosis 175:117-23. 2004
    ..CONCLUSIONS: Both wine and gin showed anti-inflammatory effects by reducing plasma fibrinogen and IL-1alpha levels. However, wine had the additional effect of decreasing hs-CRP, as well as monocyte and endothelial adhesion molecules...
  45. ncbi Effects of alcohol withdrawal on 24 hour ambulatory blood pressure among alcohol-dependent patients
    Ramon Estruch
    Alcohol Unit, Department of Internal Medicine, Hospital Clinic, University of Barcelona, Institut de Investigacions Biomediques August Pi i Sunyer, Spain
    Alcohol Clin Exp Res 27:2002-8. 2003
    ..We embarked on a study to determine whether different subgroups of alcohol-dependent patients may be identified in relation to the effect of alcohol on BP...
  46. ncbi Increased myostatin activity and decreased myocyte proliferation in chronic alcoholic cardiomyopathy
    Joaquim Fernández-Solà
    Alcohol Research Unit, Hospital Clinic, Institut d Investigació August Pi i Sunyer, Department of Medicine, University of Barcelona, Barcelona, Spain
    Alcohol Clin Exp Res 35:1220-9. 2011
    ..Myostatin is upregulated after cardiac damage and by alcohol consumption thereby decreasing myocyte renewal. We assess the potential role of alcohol in inducing myocyte apoptosis as well as in inhibiting myocyte proliferation...
  47. ncbi Human urine: epicatechin metabolites and antioxidant activity after cocoa beverage intake
    Elena Roura
    Department of Nutrition and Food Science, University of Barcelona, Barcelona, Spain
    Free Radic Res 41:943-9. 2007
    ..Significance of TAC increase was found in urine samples excreted during 0-6 and 6-12 h (66.6 and 72.67%, respectively, with respect to the 0 h)...
  48. ncbi Influence of nutritional status on alcoholic myopathy
    José M Nicolás
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Spain
    Am J Clin Nutr 78:326-33. 2003
    ..Muscle weakness and structural changes in striated skeletal muscle are common in persons with chronic alcoholism...
  49. ncbi Up-regulation of myocardial L-type Ca2+ channel in chronic alcoholic subjects without cardiomyopathy
    Francesc Fatjó
    Department of Internal Medicine, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Alcohol Clin Exp Res 31:1099-105. 2007
    ..This study was designed to evaluate the density and function of myocardial L-type Ca(2+) channel receptors in organ donors with chronic alcoholism and controls...
  50. ncbi Cross-sectional assessment of nut consumption and obesity, metabolic syndrome and other cardiometabolic risk factors: the PREDIMED study
    Núria Ibarrola-Jurado
    Human Nutrition Unit, Hospital Universitari de Sant Joan de Reus, Institut d Investigació Sanitària Pere Virgili IISPV, Universitat Rovira i Virgili, Reus, Spain
    PLoS ONE 8:e57367. 2013
    ..Limited data are available on the epidemiological associations between nut intake and cardiometabolic risk factors...
  51. ncbi The Mediterranean diet improves the systemic lipid and DNA oxidative damage in metabolic syndrome individuals. A randomized, controlled, trial
    Maria Teresa Mitjavila
    Department of Physiology, INSA, University of Barcelona, Spain
    Clin Nutr 32:172-8. 2013
    ..However, the effect of the MedDiet on biomarkers for oxidative damage has not been assessed in MetS individuals. We have investigated the effect of the MedDiet on systemic oxidative biomarkers in MetS individuals...
  52. ncbi Validation of a new LC-MS/MS method for the detection and quantification of phenolic metabolites from tomato sauce in biological samples
    Miriam Martínez-Huelamo
    Department of Nutrition and Food Science XARTA INSA, School of Pharmacy, University of Barcelona, Barcelona, Spain
    J Agric Food Chem 60:4542-9. 2012
    ..The method allowed detection and quantification limits of 0.5-29 and 2.0-90 ng mL⁻¹ in urine, respectively, and 0.5-30 and 2.0-105 ng mL⁻¹ in plasma, respectively, for the same phenolic compounds...
  53. ncbi Molecular and cellular events in alcohol-induced muscle disease
    Joaquim Fernández-Solà
    Alcohol Unit, Hospital Clinic, University of Barcelona, Spain
    Alcohol Clin Exp Res 31:1953-62. 2007
    ..Finally, ethanol induces skeletal muscle apoptosis and increases both pro- and antiapoptotic regulatory mechanisms...
  54. ncbi Attenuated total reflection infrared microspectroscopy combined with multivariate analysis: a novel tool to study the presence of cocoa polyphenol metabolites in urine samples
    Claudia Sánchez-González
    Department of Nutrition and Food Science XARTA INSA, University of Barcelona, Barcelona, Spain
    Analyst 137:3565-70. 2012
    ..Moreover, it could be a valuable tool in studies aimed to identify biomarkers of consumption of polyphenol-rich diets...
  55. ncbi High blood pressure, alcohol and cardiovascular risk
    Ramon Estruch
    Department of Medicine, Hospital Clinic, , University of Barcelona, Barcelona, Spain
    J Hypertens 23:226-9. 2005
  56. ncbi HPLC-tandem mass spectrometric method to characterize resveratrol metabolism in humans
    Mireia Urpi Sarda
    Nutrition and Food Science Department, CeRTA, Pharmacy School, University of Barcelona, Barcelona, Spain
    Clin Chem 53:292-9. 2007
    ..We sought to develop a method for nutritional analysis of resveratrol, a phenolic compound with purported health-promoting properties, and to determine all resveratrol metabolites...
  57. ncbi Rapid liquid chromatography tandem mass spectrometry assay to quantify plasma (-)-epicatechin metabolites after ingestion of a standard portion of cocoa beverage in humans
    Elena Roura
    Department of Nutrition and Food Science-CeRTA, University of Barcelona, Spain
    J Agric Food Chem 53:6190-4. 2005
    ..7 +/- 198.3 nmol/L at 2 h after consumption of a cocoa beverage containing 54.4 mg of (-)-Ec...
  58. ncbi Muscle antioxidant status in chronic alcoholism
    Joaquim Fernández-Solà
    Department of Medicine, Hospital Clinic, IDIBAPS, University of Barcelona, Spain
    Alcohol Clin Exp Res 26:1858-62. 2002
    ..Its pathogenesis is multi-factorial, only partially clarified, and antioxidant imbalance has been suggested to influence its development, being a type II glucolytic, fast-twitch fiber subset more sensitive to this effect...
  59. ncbi The effect of controlled drinking in alcoholic cardiomyopathy
    Josep Maria Nicolas
    Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Ann Intern Med 136:192-200. 2002
    ..In alcoholic persons who develop cardiac dysfunction, abstinence is thought to be essential to halt further deterioration of cardiac contractility. Some evidence indicates that reducing alcohol intake may also be beneficial...