Abel Lopez-Bermejo

Summary

Affiliation: Endocrinology and Nutrition
Country: Spain

Publications

  1. ncbi Insulin resistance after prenatal growth restriction: is it mediated by adiponectin deficiency?
    Abel Lopez-Bermejo
    Girona Institute for Biomedical Research and Dr Josep Trueta Hospital, Diabetes, Endocrinology and Nutrition Unit, Girona, Spain
    Clin Endocrinol (Oxf) 64:479-80. 2006
  2. ncbi Alpha defensins 1, 2, and 3: potential roles in dyslipidemia and vascular dysfunction in humans
    Abel Lopez-Bermejo
    Unit of Diabetes, Endocrinology, and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Arterioscler Thromb Vasc Biol 27:1166-71. 2007
  3. ncbi Potential role of interleukin-18 in liver disease associated with insulin resistance
    Abel Lopez-Bermejo
    Unit of Diabetes, Endocrinology, and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Obes Res 13:1925-31. 2005
  4. ncbi Prenatal programming of renal function: the estimated glomerular filtration rate is influenced by size at birth in apparently healthy children
    Abel Lopez-Bermejo
    Department of Pediatric Endocrinology, Dr Josep Trueta Hospital, Girona 17007, Spain
    Pediatr Res 64:97-9. 2008
  5. ncbi Insulin resistance is associated with increased serum concentration of IGF-binding protein-related protein 1 (IGFBP-rP1/MAC25)
    Abel Lopez-Bermejo
    Unit of Diabetes, Endocrinology and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Diabetes 55:2333-9. 2006
  6. ncbi Serum visfatin increases with progressive beta-cell deterioration
    Abel Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Diabetes 55:2871-5. 2006
  7. ncbi Maternal soluble tumour necrosis factor receptor type 2 (sTNFR2) and adiponectin are both related to blood pressure during gestation and infant's birthweight
    A Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition Unit, Hospital of Girona, Girona, Spain
    Clin Endocrinol (Oxf) 61:544-52. 2004
  8. ncbi Sex-specific, independent associations of insulin resistance with erythrocyte sedimentation rate in apparently healthy subjects
    Abel Lopez-Bermejo
    Unit of Diabetes, Endocrinology and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Thromb Haemost 97:240-4. 2007
  9. ncbi Both intrauterine growth restriction and postnatal growth influence childhood serum concentrations of adiponectin
    Abel Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition Unit, Dr Josep Trueta Hospital of Girona, Girona, Spain
    Clin Endocrinol (Oxf) 61:339-46. 2004
  10. ncbi Insulin resistance after precocious pubarche: relation to PAI-1-675 4G/5G polymorphism, and opposing influences of prenatal and postnatal weight gain
    Abel Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition Unit, Dr Josep Trueta Hospital, Girona, Spain
    Clin Endocrinol (Oxf) 67:493-9. 2007

Collaborators

Detail Information

Publications52

  1. ncbi Insulin resistance after prenatal growth restriction: is it mediated by adiponectin deficiency?
    Abel Lopez-Bermejo
    Girona Institute for Biomedical Research and Dr Josep Trueta Hospital, Diabetes, Endocrinology and Nutrition Unit, Girona, Spain
    Clin Endocrinol (Oxf) 64:479-80. 2006
  2. ncbi Alpha defensins 1, 2, and 3: potential roles in dyslipidemia and vascular dysfunction in humans
    Abel Lopez-Bermejo
    Unit of Diabetes, Endocrinology, and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Arterioscler Thromb Vasc Biol 27:1166-71. 2007
    ..We hypothesized that alpha-defensins 1 to 3 (DEFA1-3) are associated with serum lipids and vascular reactivity in humans...
  3. ncbi Potential role of interleukin-18 in liver disease associated with insulin resistance
    Abel Lopez-Bermejo
    Unit of Diabetes, Endocrinology, and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Obes Res 13:1925-31. 2005
    ..We hypothesized that circulating IL-18 would be related to serum concentrations of liver chemistry tests (LCTs) in apparently healthy subjects and wished to study whether this correlation was dependent on insulin sensitivity (S(I))...
  4. ncbi Prenatal programming of renal function: the estimated glomerular filtration rate is influenced by size at birth in apparently healthy children
    Abel Lopez-Bermejo
    Department of Pediatric Endocrinology, Dr Josep Trueta Hospital, Girona 17007, Spain
    Pediatr Res 64:97-9. 2008
    ..73 m. In summary, estimates of glomerular function are in apparently healthy school-age children influenced by size at birth. These findings suggest early effects for the prenatal programming of renal function in humans...
  5. ncbi Insulin resistance is associated with increased serum concentration of IGF-binding protein-related protein 1 (IGFBP-rP1/MAC25)
    Abel Lopez-Bermejo
    Unit of Diabetes, Endocrinology and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Diabetes 55:2333-9. 2006
    ..These findings show for the first time that circulating IGFBP-rP1 is increased with insulin resistance, and they also suggest novel interactions between IGFBP-rP1 and the IGF system in humans...
  6. ncbi Serum visfatin increases with progressive beta-cell deterioration
    Abel Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Diabetes 55:2871-5. 2006
    ..In summary, circulating visfatin is increased with progressive beta-cell deterioration. The study of the regulation and role of visfatin in diabetes merits further consideration...
  7. ncbi Maternal soluble tumour necrosis factor receptor type 2 (sTNFR2) and adiponectin are both related to blood pressure during gestation and infant's birthweight
    A Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition Unit, Hospital of Girona, Girona, Spain
    Clin Endocrinol (Oxf) 61:544-52. 2004
    ..We aimed to study the contributions of maternal serum concentrations of soluble TNF-alpha receptors (sTNFR1 and sTNFR2) and adiponectin to infant's birthweight...
  8. ncbi Sex-specific, independent associations of insulin resistance with erythrocyte sedimentation rate in apparently healthy subjects
    Abel Lopez-Bermejo
    Unit of Diabetes, Endocrinology and Nutrition, Dr Josep Trueta Hospital, Av Francia s n, 17007 Girona, Spain
    Thromb Haemost 97:240-4. 2007
    ..In conclusion, ESR is independently associated with either insulin resistance or obesity in a sex-specific manner. These findings contribute to explain the known relationship of this inflammatory marker with cardiovascular disease...
  9. ncbi Both intrauterine growth restriction and postnatal growth influence childhood serum concentrations of adiponectin
    Abel Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition Unit, Dr Josep Trueta Hospital of Girona, Girona, Spain
    Clin Endocrinol (Oxf) 61:339-46. 2004
    ..We aimed at studying the contributions of birthweight and insulin sensitivity to circulating adiponectin in children born small for gestational age (SGA)...
  10. ncbi Insulin resistance after precocious pubarche: relation to PAI-1-675 4G/5G polymorphism, and opposing influences of prenatal and postnatal weight gain
    Abel Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition Unit, Dr Josep Trueta Hospital, Girona, Spain
    Clin Endocrinol (Oxf) 67:493-9. 2007
    ..We hypothesized that this polymorphism is associated with precocious pubarche (PP), a population known to be at risk for hyperinsulinaemic hyperandrogenism...
  11. ncbi Adiponectin, hepatocellular dysfunction and insulin sensitivity
    Abel Lopez-Bermejo
    Unit of Diabetes, Endocrinology and Nutrition, University Hospital of Girona Dr Josep Trueta, Girona, Spain
    Clin Endocrinol (Oxf) 60:256-63. 2004
    ....
  12. ncbi Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1/MAC25) is linked to endothelial-dependent vasodilation in high-ferritin type 2 diabetes
    Abel Lopez-Bermejo
    Department of Endocrinology, Dr Josep Trueta Hospital, Girona, Spain
    Diabetes Care 30:1615-7. 2007
  13. ncbi CD14 monocyte receptor, involved in the inflammatory cascade, and insulin sensitivity
    Jose Manuel Fernandez-Real
    Section of Diabetes, Endocrinology and Nutrition, University Hospital of Girona Dr Josep Trueta, 17007 Girona, Spain
    J Clin Endocrinol Metab 88:1780-4. 2003
    ..To our knowledge, this is the first study to suggest an effect of a genetic polymorphism on both SI (healthy subjects and type 2 diabetic patients) and endothelial dysfunction (sICAM-1 levels) in type 2 diabetes mellitus...
  14. ncbi Adiponectin is associated with vascular function independent of insulin sensitivity
    Jose Manuel Fernandez-Real
    Unitat de Diabetologia, Endocrinologia i Nutricio and Servei de Medicina Interna, University Hospital of Girona Dr Josep Trueta, Girona, Spain
    Diabetes Care 27:739-45. 2004
    ..Because adiponectin appears to influence both insulin sensitivity and vessel wall physiology, we examined insulin sensitivity and vascular function in relation with circulating adiponectin...
  15. ncbi Polymorphisms in the interleukin-6 receptor gene are associated with body mass index and with characteristics of the metabolic syndrome
    Eduardo Esteve
    Department of Endocrinology, University Hospital of Girona Dr Josep Trueta, Girona, Spain
    Clin Endocrinol (Oxf) 65:88-91. 2006
    ....
  16. ncbi G protein beta3 gene variant, vascular function, and insulin sensitivity in type 2 diabetes
    Jose Manuel Fernandez-Real
    Unitat de Diabetologia, Endocrinologia i Nutricio, University Hospital of Girona Dr Josep Trueta, Girona, Spain
    Hypertension 41:124-9. 2003
    ..The GNB3 gene polymorphism might be an example of pharmacogenetics, with the underlying etiological genetic defect altering the response to treatment...
  17. ncbi Circulating visfatin is associated with parameters of iron metabolism in subjects with altered glucose tolerance
    Jose Manuel Fernandez-Real
    Department of Diabetes, Endocrinology and Nutrition, Hospital de Girona Dr Josep Trueta, Ctra França s n, 17007 Girona, Spain
    Diabetes Care 30:616-21. 2007
    ..Despite the coincidence of visfatin expression in iron-rich tissues, no study has investigated the possible interaction of visfatin with parameters of iron metabolism...
  18. ncbi Serum interleukin-6 correlates with endothelial dysfunction in healthy men independently of insulin sensitivity
    Eduardo Esteve
    Unit of Diabetes, Endocrinology, and Nutrition, Department of Internal Medicine, Hospital of Girona Dr Josep Trueta, Girona, Spain
    Diabetes Care 30:939-45. 2007
    ..We aimed to evaluate whether increased serum IL-6 concentrations associated with endothelial dysfunction are independent of insulin sensitivity in apparently healthy men...
  19. ncbi Circulating soluble CD14 monocyte receptor is associated with increased alanine aminotransferase
    Jose Manuel Fernandez-Real
    Section of Diabetes, Endocrinology and Nutrition, University Hospital of Girona Dr Josep Trueta, Girona, Spain
    Clin Chem 50:1456-8. 2004
  20. doi Association of ADIPOR2 with liver function tests in type 2 diabetic subjects
    Abel Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition Unit, Dr Josep Trueta Hospital, Girona, Spain
    Obesity (Silver Spring) 16:2308-13. 2008
    ..We studied whether common single-nucleotide polymorphisms (SNPs) in ADIPOR1 and ADIPOR2 are associated with liver function tests (LFTs) in human subjects with various degrees of insulin resistance...
  21. doi Relative hypoadiponectinemia, insulin resistance, and increased visceral fat in euthyroid prepubertal girls with low-normal serum free thyroxine
    Anna Prats-Puig
    Pediatrics, Dr Josep Trueta Hospital, Girona, Spain
    Obesity (Silver Spring) 20:1455-61. 2012
    ..These associations may be partly explained by a positive regulation of HMW-adiponectin secretion by thyroid hormone...
  22. ncbi Thyroid function is intrinsically linked to insulin sensitivity and endothelium-dependent vasodilation in healthy euthyroid subjects
    Jose Manuel Fernandez-Real
    Unit of Diabetes, Endocrinology, and Nutrition, Hospital de Girona Dr Josep Trueta, Ctra França s n, 17007 Girona, Spain
    J Clin Endocrinol Metab 91:3337-43. 2006
    ..Levels of TSH respond to fluctuations in serum free T(4) (fT(4)) but remain in a very narrow individual range. There exists current controversy regarding the upper limit of normal serum TSH values above which treatment should be indicated...
  23. doi Toward an early marker of metabolic dysfunction: omentin-1 in prepubertal children
    Anna Prats-Puig
    Pediatrics, Dr Josep Trueta Hospital, Girona, Spain
    Obesity (Silver Spring) 19:1905-7. 2011
    ..In conclusion, circulating omentin-1 may become a marker of metabolic dysfunction integrating insulin sensitivity, markers of adipose-tissue metabolism and BP as early as in prepubertal childhood...
  24. ncbi Soluble TNF-alpha receptor 2 produced by alternative splicing is paradoxically associated with markers of liver injury
    Eduardo Esteve
    Unit of Diabetes, Endocrinology and Nutrition, Hospital de Girona Dr Josep Trueta, Ctra França s n, 17007 Girona, Spain
    Clin Immunol 123:89-94. 2007
    ..These results suggest potential anti-inflammatory properties of this TNF-alpha receptor 2 isoform at the hepatic level...
  25. ncbi Circulating soluble transferrin receptor according to glucose tolerance status and insulin sensitivity
    Jose Manuel Fernandez-Real
    Unit of Diabetes, Endocrinology and Nutrition, Institut d Investigació Biomédica de Girona, Girona, Spain
    Diabetes Care 30:604-8. 2007
    ..The mechanisms of these interactions depend on poorly known factors. We aimed to study the contribution of the serum soluble transferrin receptor (sTfR)...
  26. doi Changes in circulating microRNAs are associated with childhood obesity
    Anna Prats-Puig
    MD, PhD, Section of Diabetes, Endocrinology, and Nutrition Hospital Dr Josep Trueta of Girona, Carretera de França s n, 17007 Girona, Spain
    J Clin Endocrinol Metab 98:E1655-60. 2013
    ..Circulating microRNAs (miRNAs) are valuable biomarkers of metabolic diseases and potential therapeutic targets in this field...
  27. ncbi Opposite relationship between circulating soluble CD14 concentration and endothelial function in diabetic and nondiabetic subjects
    Jose Manuel Fernandez-Real
    Unitat de Diabetologia, Endocrinologia i Nutricio and Servei de Medicina Interna, University Hospital of Girona Dr Josep Trueta, Girona, Spain
    Thromb Haemost 94:615-9. 2005
    ..While in non-diabetic subjects sCD14 behaves as an acute phase reactant, its role in type 2 diabetic patients should be further clarified. These findings need to be confirmed in further studies with larger number of patients...
  28. ncbi Novel interactions of adiponectin with the endocrine system and inflammatory parameters
    Jose Manuel Fernandez-Real
    Unit of Diabetes, Endocrinology and Nutrition, Department of Internal Medicine, University Hospital of Girona Dr Josep Trueta, 17007 Girona, Spain
    J Clin Endocrinol Metab 88:2714-8. 2003
    ....
  29. ncbi Blood letting in high-ferritin type 2 diabetes: effects on vascular reactivity
    Jose Manuel Fernandez-Real
    Unit of Diabetes, Endocrinology and Nutrition, University Hospital of Girona Dr Josep Trueta, Girona, Spain
    Diabetes Care 25:2249-55. 2002
    ..We tested the hypothesis that decreasing circulating iron stores might improve vascular dysfunction in patients with type 2 diabetes and increased serum ferritin concentration...
  30. ncbi An inflammation score is better associated with basal than stimulated surrogate indexes of insulin resistance
    Mònica Recasens
    Section of Diabetes, Endocrinology and Nutrition, University Hospital of Girona Dr Josep Trueta, Spain
    J Clin Endocrinol Metab 90:112-6. 2005
    ..Basal rather than stimulated indexes should be used in the evaluation of therapeutic measures aimed at modifying IR-associated inflammatory activity...
  31. doi Lower free thyroxin associates with a less favorable metabolic phenotype in healthy pregnant women
    Judit Bassols
    Pediatrics, Dr Josep Trueta Hospital, Avenue Francia s n, 17007 Girona, Spain
    J Clin Endocrinol Metab 96:3717-23. 2011
    ..A lower free T(4) (fT4), within the euthyroid range, has been shown in adults to associate with an adverse metabolic phenotype. Thyroid physiology changes significantly during gestation and affects maternal and fetal well-being...
  32. ncbi Iron stores, blood donation, and insulin sensitivity and secretion
    Jose Manuel Fernandez-Real
    Section of Diabetes, Endocrinology and Nutrition, University Hospital of Girona Dr Josep Trueta, Girona, Spain
    Clin Chem 51:1201-5. 2005
    ..Epidemiologists have observed that blood donation is associated with decreased risk of type 2 diabetes and cardiovascular disease...
  33. ncbi Corticosteroid-binding globulin affects the relationship between circulating adiponectin and cortisol in men and women
    Jose Manuel Fernandez-Real
    Diabetes, Endocrinology and Nutrition Research Unit, Dr Josep Trueta University Hospital of Girona, Carretera de Francia s n, 17007 Girona, Spain
    Metabolism 54:584-9. 2005
    ..In summary, circulating adiponectin, CBG concentration, and fasting cortisol were significantly interrelated in healthy subjects. A significant sexual dimorphism exists in this association...
  34. ncbi Natural antibiotics and insulin sensitivity: the role of bactericidal/permeability-increasing protein
    Carme Gubern
    Unit of Diabetes, Endocrinology and Nutrition, Hospital de Girona Dr Josep Trueta, Ctra França s n, 17007 Girona, Spain
    Diabetes 55:216-24. 2006
    ..These findings suggest that this component of the innate immune system is associated with metabolic pathways...
  35. doi Early metformin therapy (age 8-12 years) in girls with precocious pubarche to reduce hirsutism, androgen excess, and oligomenorrhea in adolescence
    Lourdes Ibanez
    Department of Endocrinology, Hospital Sant Joan de Deu, University of Barcelona, 08950 Barcelona, Spain
    J Clin Endocrinol Metab 96:E1262-7. 2011
    ..Girls with a combined history of low(-normal) birth weight (LBW) and precocious pubarche (PP) are at high risk to develop polycystic ovary syndrome (PCOS)...
  36. pmc A single nucleotide polymorphism in STK11 influences insulin sensitivity and metformin efficacy in hyperinsulinemic girls with androgen excess
    Abel Lopez-Bermejo
    Department of Pediatrics, Dr Josep Trueta Hospital, Girona, Spain
    Diabetes Care 33:1544-8. 2010
    ..Serine-threonine kinase STK11 catalyzes the AMP-activated protein kinase complex. We tested the hypothesis that a gene variant in STK11 contributes to variation in insulin sensitivity and metformin efficacy...
  37. doi A common gene variant in STK11 is associated with metabolic risk markers and diabetes during gestation
    Judit Bassols
    Department of Pediatrics, Dr Josep Trueta Hospital, Girona, Spain
    Fertil Steril 100:788-92. 2013
    ..To assess whether the common rs8111699 (C528G) variant in STK11 is related to metabolic risk markers in pregnant women and to gestational diabetes mellitus (GDM)...
  38. ncbi An alternative spliced variant of circulating soluble tumor necrosis factor-alpha receptor-2 is paradoxically associated with insulin action
    Jose Manuel Fernandez-Real
    Section of Diabetes, Endocrinology and Nutrition, University Hospital of Girona Dr Josep Trueta, Ctra França s n, 17007 Girona, Spain
    Eur J Endocrinol 154:723-30. 2006
    ..We aimed to evaluate whether this circulating DS-TNFR2 is associated with insulin action in humans...
  39. doi The association between the FTO gene and fat mass in humans develops by the postnatal age of two weeks
    Abel Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition Unit, Dr Josep Trueta Hospital, 17007 Girona, Spain
    J Clin Endocrinol Metab 93:1501-5. 2008
    ..Little is known about the genetic determinants of fat mass around birth. We hypothesized that the common rs9939609 single-nucleotide polymorphism (SNP) in FTO is associated with fat mass and metabolic parameters in neonates...
  40. doi Pubertal metformin therapy to reduce total, visceral, and hepatic adiposity
    Lourdes Ibanez
    Endocrinology, Hospital Sant Joan de Deu, University of Barcelona, Barcelona, and CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Barcelona, Spain
    J Pediatr 156:98-102.e1. 2010
    ..We tested this hypothesis in low-birthweight (LBW) girls with precocious pubarche (PP), who are at risk for hyperinsulinemic body adiposity during and beyond puberty...
  41. doi Early metformin therapy to delay menarche and augment height in girls with precocious pubarche
    Lourdes Ibanez
    Endocrinology, Hospital Sant Joan de Deu, University of Barcelona, Barcelona, and CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Madrid, Spain
    Fertil Steril 95:727-30. 2011
    ..Low-birthweight (LBW) girls with precocious pubarche (PP) are at risk for an early menarche (<12 years), an adult stature below target level, and PCOS. Hyperinsulinemic insulin resistance is thought to be a key factor...
  42. ncbi Balanced duo of anti-inflammatory SFRP5 and proinflammatory WNT5A in children
    Anna Prats-Puig
    1 Pediatrics Research Group, Girona Institute for Biomedical Research, Girona, Spain 2 Department of Pediatrics, Dr Josep Trueta Hospital, Girona, Spain
    Pediatr Res 75:793-7. 2014
    ..SFRP5 binds to wingless type mouse mammary tumor virus (MMTV) integration site family member 5A (WNT5A) to improve insulin sensitivity. We performed the first study of SFRP5 and WNT5A simultaneously in children...
  43. ncbi Burden of infection and insulin resistance in healthy middle-aged men
    Jose Manuel Fernandez-Real
    Section of Diabetes, Endocrinology and Nutrition, Institut d Investigació Biomédica de Girona, Avinguda de França s n, 17007 Girona, Spain
    Diabetes Care 29:1058-64. 2006
    ..We aimed to study the effect of exposure to four infections on insulin sensitivity in apparently healthy middle-aged men (n = 124)...
  44. doi Catch-up growth in girls born small for gestational age precedes childhood progression to high adiposity
    Lourdes Ibanez
    Endocrinology, Hospital Sant Joan de Deu, University of Barcelona, and CIBER de Diabetes y Enfermedades Metabólicas Asociadas CIBERDEM, Barcelona, Spain
    Fertil Steril 96:220-3. 2011
    ..To study across childhood the features of small for gestational age (SGA) girls with spontaneous catch-up growth...
  45. ncbi Undercarboxylated osteocalcin relates to cardiovascular risk markers in offspring of families with metabolic syndrome
    Anna Prats-Puig
    Pediatrics Research Group, Girona Institute for Biomedical Research, 17007 Girona, Spain Pediatrics, Dr Josep Trueta Hospital, 17007 Girona, Spain
    Atherosclerosis 233:272-7. 2014
    ..In offspring of families with and without metabolic syndrome (MetS+ and MetS- families), we assessed whether ucOC was related to a continuous metabolic syndrome score (MetS score) and to carotid intima-media thickness (cIMT)...
  46. ncbi The ACAA-insertion/deletion polymorphism at the 3' UTR of the IGF-II receptor gene is associated with type 2 diabetes and surrogate markers of insulin resistance
    Gemma Villuendas
    Department of Endocrinology, Hospital Universitario Ramon y Cajal and Universidad de Alcala, Carretera de Colmenar Km 9 1, Madrid E 28034, Spain
    Eur J Endocrinol 155:331-6. 2006
    ..In the present study conducted in Spaniards, we tested a common polymorphism in IGFIIR for association with type 2 diabetes and insulin-resistant traits...
  47. pmc Carboxylation of osteocalcin affects its association with metabolic parameters in healthy children
    Anna Prats-Puig
    Pediatrics, Dr Josep Trueta Hospital and Girona Institute for Biomedical Research, Girona, Spain
    Diabetes Care 33:661-3. 2010
    ..001) in heavier children. CONCLUSIONS In a weight-dependent manner, cOC and the proportion of ucOC are differentially related to HMW adiponectin and insulin secretion in healthy children...
  48. doi The alarm secretory leukocyte protease inhibitor increases with progressive metabolic dysfunction
    Abel Lopez-Bermejo
    Pediatric Endocrinology, Dr Josep Trueta Hospital, 17007 Girona, Spain
    Clin Chim Acta 412:1122-6. 2011
    ..We hypothesized that SLPI is related to chronic low-grade inflammatory diseases, such as metabolic syndrome (MS) or type-2 diabetes (T2DM)...
  49. ncbi Cross-talk between iron metabolism and diabetes
    Jose Manuel Fernandez-Real
    Unit of Diabetes, Endocrinology and Nutrition, University Hospital of Girona Dr Josep Trueta, Girona, Spain
    Diabetes 51:2348-54. 2002
    ..The study of individual susceptibility and of the mechanisms that influence tissue iron deposition and damage are proposed to be valuable in anticipating and treating diabetes complications...
  50. doi Salicylates increase insulin secretion in healthy obese subjects
    Jose Manuel Fernandez-Real
    Section of Diabetes, Endocrinology, and Nutrition, Institut d Investigació Biomédica de Girona, Avinguda de França s n, Girona, Spain
    J Clin Endocrinol Metab 93:2523-30. 2008
    ..Conflicting results on the effects of salicylates on glucose tolerance in subjects with normal glucose tolerance or type 2 diabetes have been reported...
  51. ncbi Cord serum visfatin at term birth: maternal smoking unmasks the relation to foetal growth
    Abel Lopez-Bermejo
    Diabetes, Endocrinology and Nutrition Unit, Dr Josep Trueta Hospital, Girona, Spain
    Clin Endocrinol (Oxf) 68:77-81. 2008
    ..We studied whether, at term birth, the serum concentrations of visfatin are related to foetal size, both in the absence and in the presence of maternal smoking during pregnancy...
  52. ncbi Cognitive psychosocial intervention in dementia: a systematic review
    Carme Carrion
    TransLab Research Group, Department of Medical Sciences, School of Medicine, University of Girona, Girona, Spain
    Dement Geriatr Cogn Disord 36:363-75. 2013
    ..Even though there is no specific treatment to reverse dementia, some interventions such as reality orientation and skills training can retard cognitive impairment...