Juan J Diez

Summary

Country: Spain

Publications

  1. doi request reprint An analysis of the relative risk for hypothyroidism in patients with Type 2 diabetes
    J J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Diabet Med 29:1510-4. 2012
  2. doi request reprint Relationship between serum thyrotropin concentrations and metformin therapy in euthyroid patients with type 2 diabetes
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Clin Endocrinol (Oxf) 78:505-11. 2013
  3. doi request reprint [Optimization of the medical treatment for acromegaly]
    Juan J Diez
    Servicio de Endocrinologia, Hospital Ramon y Cajal, Madrid, Espana
    Med Clin (Barc) 140:360-5. 2013
  4. doi request reprint Subclinical hyperthyroidism in patients with type 2 diabetes
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera de Colmenar Km 9, 28034, Madrid, Spain
    Endocrine 42:157-63. 2012
  5. doi request reprint Relationship between leptin and all-cause and cardiovascular mortality in chronic hemodialysis patients
    Juan Jose Diez
    Servicio de Endocrinologia, Hospital Ramon y Cajal, Madrid
    Nefrologia 31:206-12. 2011
  6. doi request reprint High stable serum adiponectin levels are associated with a better outcome in prevalent dialysis patients
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Am J Nephrol 30:244-52. 2009
  7. ncbi request reprint An analysis of the natural course of subclinical hyperthyroidism
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Am J Med Sci 337:225-32. 2009
  8. ncbi request reprint [Imaging techniques in the diagnosis of neuroendocrine tumors]
    Juan J Diez
    Servicio de Endocrinologia, Hospital Ramon y Cajal, Madrid, Espana
    Med Clin (Barc) 135:319-25. 2010
  9. ncbi request reprint The role of the novel adipocyte-derived protein adiponectin in human disease: an update
    Juan J Diez
    Servicio de Endocrinologia, Hospital Ramon y Cajal, Madrid, Spain
    Mini Rev Med Chem 10:856-69. 2010
  10. doi request reprint Prevalence of thyroid dysfunction in patients with type 2 diabetes
    J J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Exp Clin Endocrinol Diabetes 119:201-7. 2011

Detail Information

Publications45

  1. doi request reprint An analysis of the relative risk for hypothyroidism in patients with Type 2 diabetes
    J J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Diabet Med 29:1510-4. 2012
    ..We aimed to assess the relative risk for hypothyroidism in patients with Type 2 diabetes...
  2. doi request reprint Relationship between serum thyrotropin concentrations and metformin therapy in euthyroid patients with type 2 diabetes
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Clin Endocrinol (Oxf) 78:505-11. 2013
    ..We aimed to evaluate the interplay between metformin therapy and serum TSH concentrations in a group of patients with T2D and normal thyroid function...
  3. doi request reprint [Optimization of the medical treatment for acromegaly]
    Juan J Diez
    Servicio de Endocrinologia, Hospital Ramon y Cajal, Madrid, Espana
    Med Clin (Barc) 140:360-5. 2013
    ..The addition of cabergoline to somatostatin analogue therapy is accompanied by a further decrease in IGF-I levels that is independent of serum prolactin concentrations...
  4. doi request reprint Subclinical hyperthyroidism in patients with type 2 diabetes
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera de Colmenar Km 9, 28034, Madrid, Spain
    Endocrine 42:157-63. 2012
    ..The risk for subclinical hyperthyroidism is increased in women with T2D. Advanced age and the presence of goitre are significantly and independently related with the presence of subclinical hyperthyroidism in diabetic population...
  5. doi request reprint Relationship between leptin and all-cause and cardiovascular mortality in chronic hemodialysis patients
    Juan Jose Diez
    Servicio de Endocrinologia, Hospital Ramon y Cajal, Madrid
    Nefrologia 31:206-12. 2011
    ..We aimed to evaluate the relationship between serum leptin and the leptin/body mass index (BMI) ratio with prevalent cardiovascular disease (CVD), and their influence on all-cause and CVD-related mortality in patients on hemodialysis (HD)...
  6. doi request reprint High stable serum adiponectin levels are associated with a better outcome in prevalent dialysis patients
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Am J Nephrol 30:244-52. 2009
    ..Our aim was to evaluate the prognostic value of 2 measurements of serum adiponectin levels for all-cause mortality and cardiovascular (CV) mortality in uremic patients...
  7. ncbi request reprint An analysis of the natural course of subclinical hyperthyroidism
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Am J Med Sci 337:225-32. 2009
    ..Our aim was to evaluate the incidence rate of overt hyperthyroidism in a cohort of patients with subclinical hyperthyroidism and to assess the potential risk factors for the development of overt thyroid hyperfunction...
  8. ncbi request reprint [Imaging techniques in the diagnosis of neuroendocrine tumors]
    Juan J Diez
    Servicio de Endocrinologia, Hospital Ramon y Cajal, Madrid, Espana
    Med Clin (Barc) 135:319-25. 2010
    ..PET is a functional imaging technique that reflects tumor metabolism. A multimodality approach, including CT, MRI, SRS, ultrasound and endoscopy, is nowadays recommended for detecting these tumors...
  9. ncbi request reprint The role of the novel adipocyte-derived protein adiponectin in human disease: an update
    Juan J Diez
    Servicio de Endocrinologia, Hospital Ramon y Cajal, Madrid, Spain
    Mini Rev Med Chem 10:856-69. 2010
    ..According to this hypothesis, this protein would behave as an insulin sensitizing and cardioprotective factor in the health state and as a wasting marker in the advanced states of disease...
  10. doi request reprint Prevalence of thyroid dysfunction in patients with type 2 diabetes
    J J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Exp Clin Endocrinol Diabetes 119:201-7. 2011
    ..Assess the prevalence of thyroid dysfunction in patients with type 2 diabetes (T2D) in Segovia (Spain)...
  11. doi request reprint Relationship between thyrotropin and body mass index in euthyroid subjects
    J J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Exp Clin Endocrinol Diabetes 119:144-50. 2011
    ..Several studies have reported that thyrotropin (TSH) levels are slightly increased in obese subjects. On the contrary, other studies have provided no evidence for an association between thyroid status and body mass index (BMI)...
  12. ncbi request reprint Growth hormone, IGF-I and its binding proteins (IGFBP-1 and -3) in adult uraemic patients undergoing peritoneal dialysis and haemodialysis
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Clin Endocrinol (Oxf) 60:741-9. 2004
    ....
  13. ncbi request reprint Serum ghrelin concentrations in patients with chronic renal failure undergoing dialysis
    Pedro Iglesias
    Department of Endocrinology, Hospital General de Segovia, Spain
    Clin Endocrinol (Oxf) 64:68-73. 2006
    ..Derangements in ghrelin secretion in patients with chronic renal failure (CRF) have not been fully evaluated...
  14. ncbi request reprint Serum concentrations of leptin, adiponectin and resistin, and their relationship with cardiovascular disease in patients with end-stage renal disease
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Clin Endocrinol (Oxf) 62:242-9. 2005
    ....
  15. ncbi request reprint Effects of human recombinant erythropoietin on inflammatory status in peritoneal dialysis patients
    Abelardo Aguilera
    Servicio de Nefrologia, Hospitales Universitarios de la Princesa y la Paz, Madrid, Spain
    Adv Perit Dial 18:200-5. 2002
    ..By decreasing leptin, rHuEPO could increase food intake and improve the nutritional status of PD patients. At baseline, we confirm the existence of a chronic inflammatory process in uremia...
  16. ncbi request reprint Lipoatrophic diabetes in an elderly woman: clinical course and serum adipocytokine concentrations
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Ctra Avila s n, 40002 Segovia, Spain
    Endocr J 51:279-86. 2004
    ..During this period, serum adipocytokines were periodically measured. We comment on the different etiopathogenic mechanisms and the therapeutic modalities of this rare syndrome...
  17. ncbi request reprint Eating behavior disorders in uremia: a question of balance in appetite regulation
    Abelardo Aguilera
    Servicio de Nefrologia, Hospitales Universitarios de la Princesa y la Paz, Madrid, Spain
    Semin Dial 17:44-52. 2004
    ..Uremic anorexia may be explained by a hypothalamic hyperserotoninergic state derived from a high concentration of tryptophan and low branched-chain amino acids...
  18. ncbi request reprint Serum concentrations of adipocytokines in patients with hyperthyroidism and hypothyroidism before and after control of thyroid function
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Clin Endocrinol (Oxf) 59:621-9. 2003
    ..The aim of this study was to evaluate the circulating levels of leptin, adiponectin and resistin in patients with thyroid dysfunction before and after normalization of thyroid function with appropriate therapy...
  19. doi request reprint Thyroid function tests in acute kidney injury
    Pedro Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    J Nephrol 26:164-72. 2013
    ..The aim of this study was to analyze the prevalence, clinical significance and prognostic implications of alterations in thyroid function tests (TFTs) in patients with acute kidney injury (AKI)...
  20. doi request reprint Selenium and kidney disease
    Pedro Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    J Nephrol 26:266-72. 2013
    ..Available data are encouraging and stimulate interest in further studies to clarify the real extent of Se deficiency and the need for Se supplementation in patients with kidney disease...
  21. ncbi request reprint Spontaneous subclinical hypothyroidism in patients older than 55 years: an analysis of natural course and risk factors for the development of overt thyroid failure
    Juan J Diez
    Department of Endocrinology, Hospital La Paz, 28046 Madrid, Spain
    J Clin Endocrinol Metab 89:4890-7. 2004
    ..Subjects with mildly elevated TSH have a low incidence rate of overt hypothyroidism. We recommend follow-up with clinical and biochemical monitoring in these patients...
  22. ncbi request reprint Effects of cinacalcet on gastrointestinal hormone release in patients with secondary hyperparathyroidism undergoing dialysis
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera de Colmenar Km 9, 28034 Madrid, Spain
    Nephrol Dial Transplant 23:1387-95. 2008
    ....
  23. doi request reprint Insulin therapy in renal disease
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Diabetes Obes Metab 10:811-23. 2008
    ..In this study, we review the more relevant aspects related to insulin therapy in diabetic patients with different degrees of renal failure and in patients with ESRD, both in conservative therapy and dialysis...
  24. doi request reprint Hypothyrodism in male patients: a descriptive, observational and cross-sectional study in a series of 260 men
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Am J Med Sci 336:315-20. 2008
    ..Adequacy of replacement treatment seems to be mainly related to the degree of thyroid hypofunction and the time from starting therapy...
  25. doi request reprint Management of endocrine disease: a clinical update on tumor-induced hypoglycemia
    Pedro Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Ctra de Colmenar, Km 9 100, 28034 Madrid, Spain
    Eur J Endocrinol 170:R147-57. 2014
    ..Lastly, massive tumor burden with glucose consumption, massive tumor liver infiltration, and pituitary or adrenal glands destruction by tumor are other mechanisms for TIH in cases of large and aggressive neoplasias. ..
  26. ncbi request reprint Hyperthyroidism in patients older than 55 years: an analysis of the etiology and management
    Juan J Diez
    Department of Endocrinology, Hospital La Paz, Madrid, Spain
    Gerontology 49:316-23. 2003
    ....
  27. doi request reprint Acute and one-year effects of cinacalcet in patients with persistent primary hyperparathyroidism after unsuccessful parathyroidectomy
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Am J Med Sci 335:111-4. 2008
    ....
  28. ncbi request reprint Growth hormone and insulin-like growth factor binding protein-1 responses to oral glucose in patients with primary hyperparathyroidism
    Juan J Diez
    Department of Endocrinology, Hospital Ramon and Cajal, Madrid, Spain
    Clin Endocrinol (Oxf) 65:27-34. 2006
    ..GH and IGFBP-1 both play a role in glucose homeostasis...
  29. ncbi request reprint Goiter in adult patients aged 55 years and older: etiology and clinical features in 634 patients
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera de Colmenar, Km 9, 28034 Madrid, Spain
    J Gerontol A Biol Sci Med Sci 60:920-3. 2005
    ..Our aim has been to assess the frequency of the diverse etiologies of goiter in adult patients aged 55 years and older, and evaluate the relationships between etiology and age, sex, and goiter features...
  30. ncbi request reprint Influence of thyroid dysfunction on serum concentrations of adipocytokines
    Pedro Iglesias
    Department of Endocrinology, Hospital General, 40002 Segovia, Spain
    Cytokine 40:61-70. 2007
    ..Finally, discordant results in resistin levels in thyroid dysfunction have been reported in humans...
  31. ncbi request reprint Biological role, clinical significance, and therapeutic possibilities of the recently discovered metabolic hormone fibroblastic growth factor 21
    Pedro Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Ctra de Colmenar, Km 9, 100, 28034 Madrid, Spain
    Eur J Endocrinol 167:301-9. 2012
    ..Direct or indirect potentiation of its effects might be a potential therapeutic target in insulin-resistant states...
  32. doi request reprint Insulinoma-induced hypoglycemia in a patient with nesidiodysplasia after vagomotomy and pyloroplasty for duodenal ulcer
    Pedro Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Am J Med Sci 337:377-80. 2009
    ..We report, for the first time, both histologic lesions associated in a patient with a history of vagotomy and pyloroplasty for a duodenal ulcer and we discuss the possible pathogenic mechanisms...
  33. ncbi request reprint Ghrelin plasma levels and appetite in peritoneal dialysis patients
    Abelardo Aguilera
    Nephrology Services, University Hospitals La Princesa and La Paz, Instituto de Investigación Nefrológica Reina Sofía, Madrid, Spain
    Adv Perit Dial 20:194-9. 2004
    ..The role of ghrelin in appetite modulation is altered in uremic PD patients, and that alteration is possibly associated with disorders in insulin and growth hormone metabolism...
  34. ncbi request reprint Spontaneous normalization of thyrotropin concentrations in patients with subclinical hypothyroidism
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera Colmenar km 9, 28034 Madrid, Spain
    J Clin Endocrinol Metab 90:4124-7. 2005
    ..Patients with subclinical hypothyroidism may revert to normal TSH values...
  35. ncbi request reprint Serum concentrations of tumour necrosis factor-alpha (TNF-alpha) and soluble TNF-alpha receptor p55 in patients with hypothyroidism and hyperthyroidism before and after normalization of thyroid function
    Juan J Diez
    Department of Endocrinology, Hospital La Paz, Travesía Téllez 8, 4R, 28007 Madrid, Spain
    Clin Endocrinol (Oxf) 57:515-21. 2002
    ....
  36. ncbi request reprint Peroxisome proliferator-activated receptor gamma agonists in renal disease
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Segovia, Spain
    Eur J Endocrinol 154:613-21. 2006
    ..Finally, tolerability and safety profile of PPARgamma agonists in patients with reduced glomerular filtration rate are also analysed...
  37. pmc Curious cases: Acromegaly and schizophrenia: an incidental association?
    Pedro Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Schizophr Bull 40:740-3. 2014
    ..Our aim was to report new cases with both clinical entities and to discuss the potential pathophysiological mechanisms of this association...
  38. doi request reprint Prolactinomas in men: a multicentre and retrospective analysis of treatment outcome
    Pedro Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Clin Endocrinol (Oxf) 77:281-7. 2012
    ..To assess treatment outcome in male patients with micro- and macroprolactinomas...
  39. doi request reprint Gonadal dysfunction in men with chronic kidney disease: clinical features, prognostic implications and therapeutic options
    Pedro Iglesias
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    J Nephrol 25:31-42. 2012
    ..Although there are encouraging data suggesting plausible benefits from testosterone replacement therapy, further studies are needed with regards to safety and effectiveness of this therapy...
  40. ncbi request reprint The role of the novel adipocyte-derived hormone adiponectin in human disease
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Eur J Endocrinol 148:293-300. 2003
    ....
  41. doi request reprint An analysis of the relative risk for goitre in euthyroid patients with type 2 diabetes
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Madrid, Spain
    Clin Endocrinol (Oxf) 80:356-61. 2014
    ..To assess the relative risk for goitre in a cohort of euthyroid patients with type 2 diabetes with special reference to the use of metformin and insulin therapy...
  42. ncbi request reprint Hypothyroidism in patients older than 55 years: an analysis of the etiology and assessment of the effectiveness of therapy
    Juan J Diez
    Department of Endocrinology, Hospital La Paz, Madrid, Spain
    J Gerontol A Biol Sci Med Sci 57:M315-20. 2002
    ..Our aim has been to assess the relative frequency of the diverse causes of hypothyroidism in a group of patients older than 55 years and the adequacy of control of thyroid function attained by levothyroxine therapy...
  43. doi request reprint [Familial hypobetalipoproteinemia: clinical characterization of a new mutation in the APOB gene]
    Pedro Iglesias
    Servicio de Endocrinologia, Hospital General, Segovia, Espana
    Med Clin (Barc) 133:57-60. 2009
    ..Familial hypobetalipoproteinemia (FHB) is usually due to mutations in the APOB gene. Almost 60 different mutations have been reported. We report a Spanish family with FHB phenotype and a new mutation...
  44. ncbi request reprint Pharmacological therapy of Cushing's syndrome: drugs and indications
    Juan J Diez
    Department of Endocrinology, Hospital Ramon y Cajal, Carretera de Colmenar Km 9, 28034 Madrid, Spain
    Mini Rev Med Chem 7:467-80. 2007
    ..To review the main pharmacological properties and clinical applications of the drugs used in the medical therapy of Cushing's syndrome...
  45. ncbi request reprint New drugs for the treatment of hypercholesterolaemia
    Pedro Iglesias
    Department of Endocrinology, Hospital General, Ctra de Avila s n, 40002 Segovia, Spain
    Expert Opin Investig Drugs 12:1777-89. 2003
    ..Other lipid-lowering drugs with the ability to act at the enterocyte level, such as avasimibe and implitapide, are currently being investigated in humans...