Godofredo Dieguez

Summary

Country: Spain

Publications

  1. ncbi request reprint Adrenergic reactivity after inhibition of nitric oxide synthesis in the cerebral circulation of awake goats
    G Dieguez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 4, 28029, Madrid, Spain
    Brain Res 813:381-9. 1998
  2. ncbi request reprint Role of nitric oxide in the cerebral circulation during hypotension after hemorrhage, ganglionic blockade and diazoxide in awake goats
    G Dieguez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma de Madrid, Spain
    Brain Res 851:133-40. 1999
  3. ncbi request reprint Vasopressin effects on the coronary circulation after a short ischemia in anesthetized goats: role of nitric oxide and prostanoids
    Godofredo Dieguez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Eur J Pharmacol 495:171-7. 2004
  4. ncbi request reprint Enhanced response of pig coronary arteries to endothelin-1 after ischemia-reperfusion. Role of endothelin receptors, nitric oxide and prostanoids
    Belén Climent
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma de Madrid, Spain
    Eur J Pharmacol 524:102-10. 2005
  5. ncbi request reprint Coronary reactivity to endothelin-1 during partial ischemia and reperfusion in anesthetized goats. Role of nitric oxide and prostanoids
    Nuria Fernandez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Eur J Pharmacol 457:161-8. 2002
  6. ncbi request reprint Effects of antagonists for endothelin ET(A) and ET(B) receptors on coronary endothelial and myocardial function after ischemia-reperfusion in anesthetized goats
    Belén Climent
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo, 2, 28029 Madrid, Spain
    Vascul Pharmacol 44:384-90. 2006
  7. ncbi request reprint In vivo coronary effects of endothelin-1 after ischemia-reperfusion. Role of nitric oxide and prostanoids
    Nuria Fernandez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029, Madrid, Spain
    Eur J Pharmacol 481:109-17. 2003
  8. ncbi request reprint Effects of diabetes on the vascular response to nitric oxide and constrictor prostanoids: gender and regional differences
    Elena Sanz
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029, Madrid, Spain
    Life Sci 72:1537-47. 2003
  9. ncbi request reprint Vasoconstrictor prostanoids may be involved in reduced coronary reactive hyperemia after ischemia-reperfusion in anesthetized goats
    Belén Climent
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo, 2 28029 Madrid, Spain
    Eur J Pharmacol 530:234-42. 2006
  10. ncbi request reprint Coronary effects of vasopressin during partial ischemia and reperfusion in anesthetized goats. Role of nitric oxide and prostanoids
    María Angeles Martínez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo, 2, 28029 Madrid, Spain
    Eur J Pharmacol 473:55-63. 2003

Collaborators

  • Luis Monge
  • Belén Climent
  • Ana Sanchez
  • Manuel Hidalgo
  • M A Martinez
  • Nuria Fernandez
  • Angel Luis García-Villalón
  • Elena Sanz
  • Adely Salcedo
  • Jesús Garijo
  • Valentin Cuervas-Mons
  • Yesika María Amezquita
  • Juan José Montoya
  • Angel L García-Villalón
  • Angel Luis García Villalón
  • Raul Narvaez-Sanchez
  • Eduardo Ferrero
  • Gonzalo Carreño-Tarragona
  • Miriam Granado
  • Juan Carlos Figueras
  • Raul Narvaez Sanchez
  • Maria Labalde
  • Victor Sanchez Turrion
  • Víctor S Turrión
  • Víctor Sánchez Turrión
  • Juan B Martínez-León
  • María Angeles Martínez

Detail Information

Publications39

  1. ncbi request reprint Adrenergic reactivity after inhibition of nitric oxide synthesis in the cerebral circulation of awake goats
    G Dieguez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 4, 28029, Madrid, Spain
    Brain Res 813:381-9. 1998
    ....
  2. ncbi request reprint Role of nitric oxide in the cerebral circulation during hypotension after hemorrhage, ganglionic blockade and diazoxide in awake goats
    G Dieguez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma de Madrid, Spain
    Brain Res 851:133-40. 1999
    ..These differences may be related to changes in nitric oxide release as stimuli on the endothelium (shear stress and sympathetic activity) may vary in each type of hypotension...
  3. ncbi request reprint Vasopressin effects on the coronary circulation after a short ischemia in anesthetized goats: role of nitric oxide and prostanoids
    Godofredo Dieguez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Eur J Pharmacol 495:171-7. 2004
    ....
  4. ncbi request reprint Enhanced response of pig coronary arteries to endothelin-1 after ischemia-reperfusion. Role of endothelin receptors, nitric oxide and prostanoids
    Belén Climent
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma de Madrid, Spain
    Eur J Pharmacol 524:102-10. 2005
    ....
  5. ncbi request reprint Coronary reactivity to endothelin-1 during partial ischemia and reperfusion in anesthetized goats. Role of nitric oxide and prostanoids
    Nuria Fernandez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Eur J Pharmacol 457:161-8. 2002
    ....
  6. ncbi request reprint Effects of antagonists for endothelin ET(A) and ET(B) receptors on coronary endothelial and myocardial function after ischemia-reperfusion in anesthetized goats
    Belén Climent
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo, 2, 28029 Madrid, Spain
    Vascul Pharmacol 44:384-90. 2006
    ..Selective antagonists of endothelin ET(B) receptors, contrarily to those of endothelin ET(A) receptors, may be ineffective to protect coronary vasculature and myocardium against reperfusion after mild ischemia...
  7. ncbi request reprint In vivo coronary effects of endothelin-1 after ischemia-reperfusion. Role of nitric oxide and prostanoids
    Nuria Fernandez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029, Madrid, Spain
    Eur J Pharmacol 481:109-17. 2003
    ....
  8. ncbi request reprint Effects of diabetes on the vascular response to nitric oxide and constrictor prostanoids: gender and regional differences
    Elena Sanz
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029, Madrid, Spain
    Life Sci 72:1537-47. 2003
    ..These changes in vascular reactivity may be adaptative to the vascular alterations produced by diabetes...
  9. ncbi request reprint Vasoconstrictor prostanoids may be involved in reduced coronary reactive hyperemia after ischemia-reperfusion in anesthetized goats
    Belén Climent
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo, 2 28029 Madrid, Spain
    Eur J Pharmacol 530:234-42. 2006
    ..The hyperemic responses reduction during reperfusion after prolonged ischemia, but not after brief ischemia may be related at least in part to increased production of vasoconstrictor prostanoids...
  10. ncbi request reprint Coronary effects of vasopressin during partial ischemia and reperfusion in anesthetized goats. Role of nitric oxide and prostanoids
    María Angeles Martínez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo, 2, 28029 Madrid, Spain
    Eur J Pharmacol 473:55-63. 2003
    ....
  11. ncbi request reprint Goat cerebrovascular reactivity to ADP after ischemia-reperfusion. Role of nitric oxide, prostanoids and reactive oxygen species
    Ana Sanchez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo, 2, 28029 Madrid, Spain
    Brain Res 1120:114-23. 2006
    ..All these alterations may be related in part with an increased production of superoxide anion...
  12. pmc Relaxation by urocortin of human saphenous veins
    Elena Sanz
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, 28029 Madrid, Spain
    Br J Pharmacol 136:90-4. 2002
    ..Therefore, urocortin may be of significance for regulation of the venous circulation in humans...
  13. ncbi request reprint Coronary responses to endothelin-1 and acetylcholine during partial coronary ischaemia and reperfusion in anaesthetized goats
    María Angeles Martínez
    Departamento de Fisiologi a, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Clin Sci (Lond) 103:194S-197S. 2002
    ....
  14. doi request reprint Endothelin-1 potentiation of coronary artery contraction after ischemia-reperfusion
    Angel Luis García-Villalón
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, 28029 Madrid, Spain
    Vascul Pharmacol 48:109-14. 2008
    ....
  15. ncbi request reprint Coronary action of endothelin-1 and vasopressin during acute hypertension in anesthetized goats. Role of nitric oxide and prostanoids
    Nuria Fernandez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Vascul Pharmacol 41:131-8. 2004
    ..Therefore, during acute, moderate hypertension, the coronary vasoconstriction to endothelin-1 and vasopressin is attenuated, which may be related with increased NO release but not with prostanoids...
  16. ncbi request reprint Coronary effects of endothelin-1 and vasopressin during acute hypotension in anesthetized goats
    Nuria Fernandez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma de Madrid, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Life Sci 77:423-34. 2005
    ..This increased response to endothelin-1 may be related to both inhibition of NO release and release of vasoconstrictor prostanoids...
  17. ncbi request reprint Relaxation by urocortin of rat renal arteries: effects of diabetes in males and females
    Elena Sanz
    Departamento de Fisiologi a, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Cardiovasc Res 58:706-11. 2003
    ..Urocortin is a peptide structurally related to corticotropin releasing factor (CRF), and the present study was performed to examine the effects of diabetes mellitus on the relaxation by urocortin of renal arteries from males and females...
  18. ncbi request reprint Comparison of the in vivo coronary action of endothelin-1 and vasopressin role of nitric oxide and prostanoids
    María Angeles Martínez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma de Madrid, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Vascul Pharmacol 40:247-52. 2003
    ....
  19. pmc Mechanisms of the protective effects of urocortin on coronary endothelial function during ischemia-reperfusion in rat isolated hearts
    Angel Luis García-Villalón
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Br J Pharmacol 145:490-4. 2005
    ..5 These results suggest that urocortin may protect coronary endothelial function during I-R by activation of PKC...
  20. ncbi request reprint Coronary effects of endothelin-1 during acute hypertension in anaesthetized goats
    Nuria Fernandez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autónma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Clin Sci (Lond) 103:376S-379S. 2002
    ..Therefore, acute hypertension attenuates the coronary vasoconstriction caused by ET-1, and this attenuation might be related to mechanisms other than changes in NO release...
  21. ncbi request reprint Adrenergic response of splanchnic arteries from cirrhotic patients: role of nitric oxide, prostanoids, and reactive oxygen species
    Adely Salcedo
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Madrid, Spain
    Exp Biol Med (Maywood) 232:1360-7. 2007
    ..Products dependent on NAD(P)H oxidase might contribute to the adrenergic response in splanchnic arteries from control and cirrhotic patients...
  22. ncbi request reprint Role of K(+) channels in the coronary and renal vascular reactivity to vasopressin in diabetic rats
    Elena Sanz
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Eur J Pharmacol 471:35-40. 2003
    ..The effects of diabetes on this vasoconstriction are not related to increased release of superoxide radicals...
  23. doi request reprint Role of alpha-adrenoceptors and prostacyclin in the enhanced adrenergic reactivity of goat cerebral arteries after ischemia-reperfusion
    Luis Monge
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, 28029 Madrid, Spain
    Brain Res 1346:121-31. 2010
    ..After ischemia-reperfusion, noradrenaline might increase PGI(2) production thus contributing to adrenergic vasoconstriction and/or PGI(2) would potentiate the noradrenaline effects...
  24. ncbi request reprint Effect of ischemia duration and nitric oxide on coronary vasoconstriction after ischemia-reperfusion
    Angel Luis García-Villalón
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, Madrid 28029, Spain
    Eur J Pharmacol 509:165-70. 2005
    ..Longer ischemias may non-specifically inhibit coronary vasoconstriction and reduce nitric oxide production...
  25. ncbi request reprint Potentiation by endothelin-1 and vasopressin of sympathetic vasoconstriction in male and female rats
    Nuria Fernandez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Clin Sci (Lond) 103:158S-161S. 2002
    ....
  26. ncbi request reprint Relaxation of rat arteries by urocortin: effects of gender and diabetes
    Elena Sanz
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029 Madrid, Spain
    J Pharm Pharmacol 55:783-8. 2003
    ..The mechanisms underlying this relaxation in tail arteries might differ between males and females...
  27. doi request reprint Coronary response to diadenosine triphosphate after ischemia-reperfusion in the isolated rat heart
    Angel Luis García-Villalón
    Departamento de Fisiologia, Universidad Autonoma de Madrid, Madrid, Spain
    Exp Biol Med (Maywood) 237:966-72. 2012
    ..This impairment of vasodilation may contribute to the coronary dysregulation that occurs during ischemia-reperfusion...
  28. doi request reprint Response to endothelin-1 in arteries from human colorectal tumours: role of endothelin receptors
    Eduardo Ferrero
    Departamento de Cirugía General y Digestiva Section B, Hospital Universitario 12 de Octubre, Universidad Complutense, Madrid, Spain
    Exp Biol Med (Maywood) 233:1602-7. 2008
    ....
  29. doi request reprint Coronary response to diadenosine tetraphosphate after ischemia-reperfusion in the isolated rat heart
    Angel Luis García-Villalón
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma de Madrid, Arzobispo Morcillo 4, 28029 Madrid, Spain
    Eur J Pharmacol 660:394-401. 2011
    ..These results suggest that the coronary relaxation to Ap4A is reduced after ischemia-reperfusion, and that this reduction may be due to impaired effects of KATP channels and to reduced response of purinergic P2Y receptors...
  30. pmc Mechanisms of relaxation by urocortin in renal arteries from male and female rats
    Elena Sanz
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Madrid 28029, Spain
    Br J Pharmacol 140:1003-7. 2003
    ..In female rats, this relaxation may be mediated by the production of cyclic AMP (cAMP), synthesis of cADPR and release of sarcoplasmic Ca2+, whereas in male rats it is not mediated by cAMP...
  31. doi request reprint Dilator and constrictor response of renal vasculature during acute renal hypotension in anesthetized goats. Role of nitric oxide
    Godofredo Dieguez
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, 28029 Madrid, Spain
    Vascul Pharmacol 54:107-11. 2011
    ....
  32. ncbi request reprint Urocortin protects coronary endothelial function during ischemia-reperfusion: a brief communication
    Angel Luis García-Villalón
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, 28029 Madrid, Spain
    Exp Biol Med (Maywood) 229:118-20. 2004
    ..These results suggest that ischemia-reperfusion impairs the coronary vasodilation to urocortin and produces endothelial dysfunction and that this endothelial dysfunction may be improved by urocortin...
  33. doi request reprint Nitric oxide-mediated relaxation to lactate of coronary circulation in the isolated perfused rat heart
    Juan José Montoya
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma de Madrid, Madrid, Spain
    J Cardiovasc Pharmacol 58:392-8. 2011
    ..These findings may be relevant for the regulation of coronary circulation when lactate levels are elevated...
  34. doi request reprint Coronary response to diadenosine pentaphosphate after ischaemia-reperfusion in the isolated rat heart
    Angel Luis García-Villalón
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma de Madrid, Arzobispo Morcillo 2, 28029 Madrid, Spain
    Cardiovasc Res 81:336-43. 2009
    ..The objective of this study was to analyse their effects in such conditions...
  35. doi request reprint Role of angiotensin II in the response to endothelin-1 of goat cerebral arteries after ischemia-reperfusion
    Adely Salcedo
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo, 4, 28029 Madrid, Spain
    Vascul Pharmacol 50:160-5. 2009
    ..The observed cerebrovascular increased response to endothelin-1 after ischemia-reperfusion might be related in part to activation of AT1 receptors under this condition...
  36. doi request reprint Effects of endothelin-1 on the relaxation of rat coronary arteries
    Angel Luis García-Villalón
    Departamento de Fisiologia, Universidad Autonoma, Madrid, Spain
    J Cardiovasc Pharmacol 54:445-50. 2009
    ..These results suggest that endothelin-1 may potentiate coronary beta-adrenergic vasodilatation, at least in part due to stimulation of endothelin ET(A) receptors and activation of protein kinase C...
  37. ncbi request reprint Vascular reactivity to vasopressin during diabetes: gender and regional differences
    Angel Luis García-Villalón
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Arzobispo Morcillo 2, 28029, Madrid, Spain
    Eur J Pharmacol 459:247-54. 2003
    ..Therefore, the effects of diabetes on vascular reactivity to vasopressin may differ between vascular beds, and the mechanisms underlay these effects may be distinct between genders...
  38. ncbi request reprint Endothelium-dependent relaxation of isolated splanchnic arteries from cirrhotic patients: Role of reactive oxygen species
    Adely Salcedo
    Department of Physiology, University Hospital Puerta de Hierro, Faculty of Medicine, Autonomous University, Madrid, Spain
    Hepatol Res 37:811-9. 2007
    ..Conclusions: Cirrhosis may decrease endothelial release and/or bioavailability of nitric oxide and prostacyclin in splanchnic arteries, which might be caused partly by increased production of reactive oxygen species...
  39. ncbi request reprint Apelin effects in human splanchnic arteries. Role of nitric oxide and prostanoids
    Adely Salcedo
    Departamento de Fisiologia, Facultad de Medicina, Universidad Autonoma, Madrid, Spain
    Regul Pept 144:50-5. 2007
    ..This relaxation as well as the role of nitric oxide may be decreased in splanchnic arteries from cirrhotic patients...