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Species | Silvia de SanjoseSummaryCountry: Spain Publications
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Publications
HPV Prevention seriesSilvia de Sanjose
Unit of Infections and Cancer, Cancer Epidemiology Research Programme, Institut Catala d Oncologia, Av, Gran Via de l Hospitalet 199 203, 08908 L Hospitalet de Llobregat, Barcelona, Spain
Infect Agent Cancer 7:37. 2012..Articles within a wide range of topics such as natural history studies, impact of screening interventions or impact of HPV vaccines will be most welcome...
Potential impact of a nine-valent vaccine in human papillomavirus related cervical diseaseBeatriz Serrano
Unit of Infections and Cancer UNIC, Cancer Epidemiology Research Program CERP, IDIBELL, Institut Català d Oncologia ICO Catalan Institute of Oncology, Gran Via de L Hospitalet, 199 203, L Hospitalet de Llobregat, Barcelona, Spain
Infect Agent Cancer 7:38. 2012..abstract:..
Human papillomavirus prevalence and type-specific relative contribution in invasive cervical cancer specimens from ItalyLuciano Mariani
Regina Elena National Cancer Institute, Dept Gynecologic Oncology, Roma, Italy
BMC Cancer 10:259. 2010..Human papillomavirus (HPV) infection is now well-established as a necessary cause of invasive cervical cancer (ICC) development. Only a few studies on HPV prevalence and type-specific distribution in ICC have been conducted in Italy...
Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide studySilvia de Sanjose
IDIBELL, Institut Català d Oncologia Catalan Institute of Oncology, L Hospitalet de Llobregat, Barcelona, Spain
Lancet Oncol 11:1048-56. 2010..We aimed to provide novel and comprehensive data about the worldwide genotype distribution in patients with invasive cervical cancer...
Association between personal use of hair dyes and lymphoid neoplasms in EuropeSilvia de Sanjose
Catalan Institute of Oncology, Barcelona, Spain
Am J Epidemiol 164:47-55. 2006..10, 2.40). Personal use of hair dyes is associated with a moderate increase in lymphoma risk, particularly among women and persons who used dyes before 1980. Specific compounds associated with this risk remain to be elucidated...
Epstein-Barr virus infection and risk of lymphoma: immunoblot analysis of antibody responses against EBV-related proteins in a large series of lymphoma subjects and matched controlsSilvia de Sanjose
Servei d Epidemiologia and Registre del Cancer, IDIBELL, Institut Catala d Oncologia, Gran Via Km 2 7, 08907 L Hospitalet, Barcelona, Spain
Int J Cancer 121:1806-12. 2007..Ab_EBV is a useful tool to explore EBV imbalances preceding or paralleling possible EBV associated oncogenic events...
Geographic variation in the prevalence of Kaposi sarcoma-associated herpesvirus and risk factors for transmissionSilvia de Sanjose
Institut Catala d Oncologia, and 2Centro de Investigación Biomédica en Red de Epidemiologia y Salud Pública, Barcelona, Spain
J Infect Dis 199:1449-56. 2009..The aim of the present study was to estimate the prevalence of Kaposi sarcoma-associated herpesvirus (KSHV) in the female general population, to define geographic variation in and heterosexual transmission of the virus...
Human papillomavirus vaccines and vaccine implementationSilvia de Sanjose
Unit of Infections and Cancer UNIC, Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL and CIBER Epidemiología y Salud Pública CIBERESP, Barcelona, Spain
Womens Health (Lond Engl) 4:595-604. 2008..Finally, some major aspects that are likely to impact the introduction of these vaccines around the world are outlined, with particular emphasis on developing countries...
Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysisSilvia de Sanjose
Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, Barcelona, Spain
Lancet Infect Dis 7:453-9. 2007..The HPV types most commonly detected are similar to those most commonly described in pre-neoplastic and cancer cases, although the relative contribution of HPV16 and HPV18 is substantially lower in cytologically normal women...
Age at sexual initiation and number of sexual partners in the female Spanish population Results from the AFRODITA surveySilvia de Sanjose
Unit of Infections and Cancer, Cancer Epidemiology Research Program, Catalan Institut of Oncology, Hospitalet del Llobregat, Spain
Eur J Obstet Gynecol Reprod Biol 140:234-40. 2008..The AFRODITA study was designed to describe patterns relating to the number of lifetime sexual partners (SP) and age at first sexual intercourse (AFSI) by geographic region in a representative sample of Spanish women...
Hepatitis C and non-Hodgkin lymphoma among 4784 cases and 6269 controls from the International Lymphoma Epidemiology ConsortiumSilvia de Sanjose
Unit of Infections and Cancer, Catalan Institute of Oncology, Institut d Investigacio Biomedica de Bellvitge, Centro de Investigación Biomédica en Red Epidemiología y Salud Pública, Barcelona, Spain
Clin Gastroenterol Hepatol 6:451-8. 2008..We pooled case-control study data to provide robust estimates of the risk of non-Hodgkin's lymphoma (NHL) subtypes after HCV infection...
Worldwide human papillomavirus etiology of cervical adenocarcinoma and its cofactors: implications for screening and preventionXavier Castellsague
Institut d Investigacio Biomedica de Bellvitge, Cancer Epidemiology and Registration Unit, Institut Català d Oncologia L Hospitalet de Llobregat, Barcelona, Spain
J Natl Cancer Inst 98:303-15. 2006..The extent to which human papillomavirus (HPV) infection and cofactors may explain this differential trend is unclear...
Cervical human papillomavirus infection in the female population in Barcelona, SpainSilvia de Sanjose
Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, Gran Via km 2 7 E 08907 L Hospitalet de Llobregat, Barcelona, Spain
Sex Transm Dis 30:788-93. 2003..Human papillomavirus (HPV) is a major cause of invasive cervical cancer. Identification of HPV determinants might allow for targeting of high-risk groups for cervical cancer...
Chlamydia trachomatis infection in female partners of circumcised and uncircumcised adult menXavier Castellsague
Cancer Epidemiology and Registration Unit, Institut d Investigacio Biomedica de Bellvitge, Institut Catala d Oncologia, L Hospitalet de Llobregat, Barcelona, Spain
Am J Epidemiol 162:907-16. 2005..These findings suggest that male circumcision could reduce the risk of C. trachomatis infection in female sexual partners...
Intrauterine device use, cervical infection with human papillomavirus, and risk of cervical cancer: a pooled analysis of 26 epidemiological studiesXavier Castellsague
Unit of Infections and Cancer, Cancer Epidemiology Research Program, Institut Catala d Oncologia, Bellvitge Biomedical Research Institute, L Hospitalet de Llobregat, Catalonia, Spain
Lancet Oncol 12:1023-31. 2011..We assessed whether IUD use affects cervical human papillomavirus (HPV) infection and the risk of developing cervical cancer...
Role of hepatitis C virus infection in malignant lymphoma in SpainSilvia de Sanjose
Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, Barcelona, Spain
Int J Cancer 111:81-5. 2004..HCV infection is associated with an increased risk of a broad spectrum of lymphoid neoplasms among non severely immunocompromised subjects in Spain...
Male circumcision, penile human papillomavirus infection, and cervical cancer in female partnersXavier Castellsague
Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, Hospitalet de Llobregat, Barcelona, Spain
N Engl J Med 346:1105-12. 2002..It is uncertain whether male circumcision reduces the risks of penile human papillomavirus (HPV) infection in the man and of cervical cancer in his female partner...
Frequent polymorphic changes but not mutations of TRAIL receptors DR4 and DR5 in mantle cell lymphoma and other B-cell lymphoid neoplasmsVeronica Fernandez
Hematopathology Section, Laboratory of Pathology, Hematology Department, Hospital Clinic, Institut d Investigacions Biomèdiques August Pi iSunyer, University of Barcelona, Barcelona, Spain
Haematologica 89:1322-31. 2004..Tumor necrosis factor related apoptosis-inducing ligand (TRAIL) receptors DR4 and DR5 have been mapped to chromosome 8p21-22, a region frequently deleted in different lymphoid neoplasms...
Cervical human papillomavirus prevalence in 5 continents: meta-analysis of 1 million women with normal cytological findingsLaia Bruni
Unit of Infections and Cancer, Cancer Epidemiology Research Program, IDIBELL Institut Català d Oncologia, Barcelona, Spain
J Infect Dis 202:1789-99. 2010..Baseline information on human papillomavirus (HPV) prevalence and type distribution is highly desirable to evaluate the impact of prophylactic HPV vaccines in the near future...
Helicobacter pylori and malignant lymphoma in SpainSilvia de Sanjose
Servei d Epidemiologia and Registre del Cancer, Institut Catala d Oncologia, Gran Via Km 2 7, 08907 L Hospitalet, Barcelona, Spain
Cancer Epidemiol Biomarkers Prev 13:944-8. 2004..Helicobacter pylori has been associated with gastric adenocarcinoma and gastric lymphoma. We report on the systematic evaluation of serologic detection of H. pylori in a lymphoma case-control study...
Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymphDelphine Casabonne
Unit of Infections and Cancer UNIC, IDIBELL, Institut Catala d Oncologia, L Hospitalet de Llobregat, Barcelona, Spain
Haematologica 96:323-7. 2011..All interactions were additive and no main effect was observed. The strong interactions observed may be indicative of a specific pathway in cancer genesis. Confirmation of these results is warranted...
Regular use of hair dyes and risk of lymphoma in SpainYolanda Benavente
Servei d'Epidemiologia and Registre del Cancer, IDIBELL, Institut Catala d'Oncologia, Barcelona, Spain
Int J Epidemiol 34:1118-22. 2005..3, 95% CI 1.1-4.7). The risk of CLL increased with lifetime doses received. CONCLUSIONS: Ever use of hair dye products is unlikely to substantially modify the risk of lymphoma. The observed association with CLL needs to be replicated...
Human Papillomavirus (HPV) infection in pregnant women and mother-to-child transmission of genital HPV genotypes: a prospective study in SpainXavier Castellsague
Unit of Infections and Cancer UNIC, Cancer Epidemiology Research Program CERP, IDIBELL Institut Català d Oncologia ICO, Hospitalet de Llobregat, Barcelona, Spain
BMC Infect Dis 9:74. 2009..Studies on HPV infection in pregnant women and HPV transmission to the child have yielded inconsistent results...
Concordance of prevalence of human papillomavirus DNA in anogenital and oral infections in a high-risk populationM Paz Cañadas
Departament de Biologia Molecular, General Lab, Barcelona, Spain
J Clin Microbiol 42:1330-2. 2004..HPV was found in 43.6% of the women, and its prevalence at genital sites was similar. Prevalence was highest among women aged 20 years or younger but declined thereafter in specimens from all anogenital sites...
Reproductive factors and lymphoid neoplasms in Europe: findings from the EpiLymph case-control studyLaura Costas
Unit of Infections and Cancer, Cancer Epidemiology Research Programme, Institut Catala d Oncologia, IDIBELL, Av Gran Via de L Hospitalet 199 203, 08908, L Hospitalet de Llobregat, Barcelona, Spain
Cancer Causes Control 23:195-206. 2012..Higher incidence rates are observed for many lymphoma subtypes in men compared with women suggesting an underlying association. Our goal was to investigate the association between reproductive factors and lymphomas...
Impact of interleukin-10 polymorphisms (-1082 and -3575) on the survival of patients with lymphoid neoplasmsEva Domingo-Domenech
Department of Hematology, Institut Catala d Oncologia, Avda Gran Via s n, Km 2 7, 08907 L Hospitalet de Llobregat, Barcelona, Spain
Haematologica 92:1475-81. 2007..The aim of this study was to explore the association between polymorphisms of IL-10-(1082A>G) and IL-10-(3575T>A) with the overall survival in patients with lymphoid neoplasms...
Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemiaAnna Enjuanes
Department of Anatomic Pathology, Hematopathology Section, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
Cancer Res 68:10178-86. 2008..This study suggests that common genetic variation in apoptosis- and immunoregulation-related genes is associated with the CLL risk...
Vaccine-related HPV genotypes in women with and without cervical cancer in Mozambique: burden and potential for preventionXavier Castellsague
IDIBELL, Institut Català d Oncologia ICO, L Hospitalet de Llobregat, Barcelona, Spain
Int J Cancer 122:1901-4. 2008..The introduction of an efficacious HPV 16/18 vaccine could potentially prevent the occurrence of 72% of cervical cancer cases and up to 81% of the cases if full cross-protection against HPVs 31 and 45 is assumed...
Comparison of 2 different PCR-based technologies for the detection of human papilloma virus from paraffin-embedded tissue: genómica clinical arrays versus SPF(10)-LiPA(25)Cristina Perez
Department of Pathology, San Agustín Hospital of Avilés, University Institute of Oncology, Principality of Asturias Asturias, Barcelona, Spain
Diagn Mol Pathol 21:45-52. 2012..05). Our study highlights an important difference between 2 PCR-based methods for detection and genotyping of HPV. LiPA25 SPF10-PCR technology may be more adequate than Genómica for the detection of HPV DNA when using FFPE tissue...
Celiac disease and lymphoma risk: a multicentric case--control study in SpainCarme Farré
Hospital Sant Joan de Deu, Barcelona, Spain
Dig Dis Sci 49:408-12. 2004..In our series, there was no evidence that celiac disease was a risk factor for lymphoma (OR = 0.62, 95% CI = 0.10-3.79). Serological screening for CD is not recommended in people with lymphoma...
The epidemiology of human papillomavirus infection and cervical cancerF Xavier Bosch
Institut Catala d Oncologia, Epidemiology and Cancer Registration Unit, E 08907 L Hospitalet de Llobregat, Barcelona, Spain
Dis Markers 23:213-27. 2007..Women exposed to the Human Immunodeficiency Virus (HIV) are at high risk for HPV infection, HPV DNA persistency and progression of HPV lesions to cervical cancer...
Prevalence of Kaposi's sarcoma-associated herpesvirus infection in sex workers and women from the general population in SpainSilvia de Sanjose
Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, L Hospitalet de Llobregat, Barcelona, Spain
Int J Cancer 98:155-8. 2002..All PBMC samples were negative. These results suggest that in low-risk countries for KSHV, oral shedding and heterosexual contacts are potential pathways for KSHV transmission...
Immunoglobulin E levels and risk of lymphoma in a case-control study in SpainLis Ellison Loschmann
Epidemiology and Cancer Registry Unit, Institut Catala d Oncologia, Gran Via Km 2 7, 08907 L Hospitalet de Ll, Barcelona, Spain
Cancer Epidemiol Biomarkers Prev 16:1492-8. 2007..Long-term cohort studies may be fundamental to fully evaluate these associations...
Human papillomavirus genotype distribution in cervical cancer cases in Spain. Implications for preventionLaia Alemany
IDIBELL, Institut Català d Oncologia Catalan Institute of Oncology, L Hospitalet de Llobregat, Barcelona, Spain
Gynecol Oncol 124:512-7. 2012..Human papillomavirus (HPV) genotype distribution in invasive cervical cancer (ICC) is critical to guide the introduction and to assess the impact of HPV prophylactic vaccines. This study aims to provide specific information for Spain...
Human papillomavirus in cervical cancerF Xavier Bosch
Servei dEpidemiologia i Registre del Càncer, Institut Català dOncologia, Av Gran Via, s n km 2 7, 08907 LHospitalet de Llobregat, Barcelona, Spain
Curr Oncol Rep 4:175-83. 2002....
Occupational exposure to immunologically active agents and risk for lymphomaManolis Kogevinas
Servei d'Epidemiologia and Registre del Cancer, Institut Catala d'Oncologia, Gran Via Km 2.7, 08907 L'Hospitalet, Barcelona, Spain
Cancer Epidemiol Biomarkers Prev 13:1814-8. 2004..60 (0.53-4.84)], although overall there was no increased risk for T-cell lymphomas. CONCLUSIONS: Exposure to immunologically active agents among clinically immunocompetent subjects was associated with risk for Hodgkin's lymphoma...
Epidemiology and natural history of human papillomavirus infections and type-specific implications in cervical neoplasiaF Xavier Bosch
Cancer Epidemiology Research Program CERP, Institut Català d Oncologia Catalan Institute of Oncology ICO, L Hospitalet de Llobregat Barcelona, Spain
Vaccine 26:K1-16. 2008....
Occupational exposure to high molecular weight allergens and lymphoma risk among Italian adultsMaria C Mirabelli
Centre for Research in Environmental Epidemiology, Barcelona, Spain
Cancer Epidemiol Biomarkers Prev 18:2650-4. 2009..The present analysis was conducted to assess the associations between occupational exposure to specific HMW allergens and the risk of B-cell, T-cell, and Hodgkin's lymphomas...
Prediction of cervical intraepithelial neoplasia grade 2+ (CIN2+) using HPV DNA testing after a diagnosis of atypical squamous cell of undetermined significance (ASC-US) in Catalonia, SpainRaquel Ibanez
Unit of Infections and Cancer, Cancer Epidemiology Research Programme, IDIBELL, Catalan Institute of Oncology, Av, Gran Via, 199 203L Hospitalet de Llobregat, 08907 Barcelona, Spain
BMC Infect Dis 12:25. 2012..We evaluated the implementation of the protocol and the prediction of HPV testing as a triage tool for cervical intraepithelial lesions grade two or worse (CIN2+) in women with a cytological diagnosis of ASC-US...
Cost-effectiveness of human papillomavirus vaccination and screening in SpainMireia Diaz
Unit of Infections and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology, IDIBELL, Av Gran Vía 199 203, 08907 L Hospitalet de Llobregat, Barcelona, Spain
Eur J Cancer 46:2973-85. 2010..Screening is opportunistic (annual/biannual) contributing to social and geographical disparities...
Antibody response to Merkel cell polyomavirus associated with incident lymphoma in the Epilymph case-control study in SpainClaudia Robles
Unit of Infections and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, L Hospitalet de Llobregat, Barcelona, Spain
Cancer Epidemiol Biomarkers Prev 21:1592-8. 2012..To investigate this potential role, we explored seroreactivity against MCV VP1 capsids within the Epilymph case-control study in Spain...
Prevalence of BRCA1 and BRCA2 germline mutations in young breast cancer patients: a population-based studySilvia de Sanjose
Institut Catala d Oncologia, Hospitalet de LL, Barcelona, Spain
Int J Cancer 106:588-93. 2003..The contribution of these genes to early-onset breast cancer is likely to be even higher given that certain UV cases might be disease-associated...
Lack of serological evidence for an association between simian virus 40 and lymphomaSilvia de Sanjose
Institut Catala d Oncologia, Barcelona, Spain
Int J Cancer 104:522-4. 2003..VLPs of the human BK virus substantially inhibited the SV40 reactivity of human sera. There was no serological evidence of widespread SV40 infection and no association of SV40 seropositivity with human lymphomas in Spain...
Analysis of Aurora-A and hMPS1 mitotic kinases in mantle cell lymphomaEmma Camacho
Department of Pathology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
Int J Cancer 118:357-63. 2006..Although the Aurora-A P31I polymorphic variant is not directly involved in a genetic predisposition to these lymphomas, it may modulate the clinical presentation of these tumors...
Cervical and anal HPV infections in HIV positive women and menSilvia de Sanjose
Department of Epidemiology and Cancer Registry, Catalan Institute of Oncology, Gran Via Km 2 7, 08907 Hospitalet de Ll, Barcelona, Spain
Virus Res 89:201-11. 2002..Full screening for CIN remains necessary in HIV-positive women and it is likely that screening for AIN will be beneficial as well to prevent invasive anogenital cancer in long-term AIDS survivors...
The prospects of HPV vaccination in cervical cancer prevention: results of a new independent trialF Xavier Bosch
Cancer Epidemiology Research Program CERP, Catalan Institute of Oncology Institut Català d Oncologia ICO and Bellvitge Biomedical Research Institute, Avenida Gran Via 199 203, L Hospitalet de Llobregat, Barcelona, Spain
Cancer Discov 1:377-80. 2011....
Biological convergence of cancer signaturesXavier Sole
Bioinformatics and Biostatistics Unit, Catalan Institute of Oncology, IDIBELL, L Hospitalet, Barcelona, Spain
PLoS ONE 4:e4544. 2009..Examination of additional, independent, cancer datasets corroborated our observations. This study proposes a comprehensive strategy for interpreting cancer signatures that reveals common design principles and systems-level properties...
Performance of the digene LQ, RH and PS HPVs genotyping systems on clinical samples and comparison with HC2 and PCR-based Linear ArrayJose M Godínez
Unit of Infections and Cancer UNIC, Cancer Epidemiology Research Program CERP, IDIBELL, Catalan Institute of Oncology ICO, Gran Via 199 203, L Hospitalet de Llobregat 08907, Barcelona, Spain
Infect Agent Cancer 6:23. 2011..abstract:..
Common Infectious Agents and Monoclonal B-Cell Lymphocytosis: A Cross-Sectional Epidemiological Study among Healthy AdultsDelphine Casabonne
Unit of Infections and Cancer UNIC, IDIBELL, Institut Catala d Oncologia, L Hospitalet de Llobregat, Barcelona, Spain CIBER Epidemiología y Salud Pública CIBERESP, Barcelona, Spain
PLoS ONE 7:e52808. 2012..Risk factors associated with monoclonal B-cell lymphocytosis (MBL), a potential precursor of chronic lymphocytic leukaemia (CLL), remain unknown...
NT-proBNP: a cardiac biomarker to assess prognosis in non-Hodgkin lymphomaEva Gimeno
Department of Clinical Hematology, Hospital Universitari del Mar, Barcelona, Spain
Leuk Res 35:715-20. 2011..These findings suggest that NT-proBNP ≥ 900 pg/ml could be considered a useful marker for risk assessment in NHL patients treated with chemotherapy...
Polymorphisms in candidate obesity genes and their interaction with dietary intake of n-6 polyunsaturated fatty acids affect obesity risk in a sub-sample of the EPIC-Heidelberg cohortAlexandra Nieters
German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Eur J Nutr 41:210-21. 2002....
Anthropometric characteristics and non-Hodgkin's lymphoma and multiple myeloma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)Julie A Britton
Department of Epidemiology and Public Health, Imperial College London, Room 151, St Mary s Campus, Norfolk Place W2 1PG, London, UK
Haematologica 93:1666-77. 2008..It has been hypothesized that this may be due, in part, to the parallel rising prevalence of obesity. It is biologically plausible that anthropometric characteristics can infuence the risk of non-Hodgkin's lymphoma and multiple myeloma...
Fruit and vegetable consumption and lymphoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)Sabine Rohrmann
Division of Clinical Epidemiology C020, German Cancer Research Centre, Im Neuenheimer Feld 280, Heidelberg, 69120, Germany
Cancer Causes Control 18:537-49. 2007..The best-established risk factors are related to dys-regulation of immune function, and evidence suggests that factors such as dietary or lifestyle habits may be involved in the etiology...
Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and NutritionMazda Jenab
Nutrition and Hormones Group, IARC WHO, Lyon, France
Int J Cancer 121:368-76. 2007..No clear colorectal cancer risk associations were observed for IGFBP-1 or -2. This large prospective study confirms that hyperinsulinemia, as determined by C-peptide levels, is associated with an increased colorectal cancer risk...
Sun exposure and malignant lymphoma: a population-based case-control study in GermanyThomas Weihkopf
Institute of Medical Biostatistics, Epidemiology and Informatics, Johannes Gutenberg University, Mainz, Germany
Int J Cancer 120:2445-51. 2007..This data suggest that exposure to natural and artificial ultraviolet radiation may reduce the OR for lymphoma in this study population...
Influence of familial cancer history on lymphoid neoplasms risk validated in the large European case-control study epilymphRomain Casey
Registre des Hémopathies Malignes de Côte d Or, EA INSERM InVs 4T0003C, faculté de médecine de Dijon, 7 Boulevard Jeanne d Arc, 21 000 Dijon, France
Eur J Cancer 42:2570-6. 2006..Our study suggests familial aggregation of CLL with a family history of haematological cancer and of HL with a family history of lymphoma. The transmission pattern suggests a dominant model of heredity...
Tobacco and alcohol consumption and risk of lymphoma: results of a population-based case-control study in GermanyAlexandra Nieters
Division of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany
Int J Cancer 118:422-30. 2006..In conclusion, this investigation suggests a positive association between tobacco smoking and lymphoma risk and finds decreased odds ratios among consumers of alcohol...
Hepatitis C and risk of lymphoma: results of the European multicenter case-control study EPILYMPHAlexandra Nieters
German Cancer Research Center, Heidelberg, Germany
Gastroenterology 131:1879-86. 2006..However, previous epidemiologic studies were limited in size to establish an association between HCV infection and specific lymphoma subtypes. We performed a large, multicenter, case-control study to address this question...
Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutritionTeresa Norat
International Agency for Research on Cancer, 150 cours Albert Thomas, 69 372 Lyon cedex 08, France
J Natl Cancer Inst 97:906-16. 2005..CONCLUSIONS: Our data confirm that colorectal cancer risk is positively associated with high consumption of red and processed meat and support an inverse association with fish intake...
Medical history and risk for lymphoma: results of a population-based case-control study in GermanyNikolaus Becker
German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
Eur J Cancer 41:133-42. 2005..These results are compatible with the notion that persistent immunological alterations contribute to the aetiology of lymphoma, but partially inconsistent with the Th1/Th2-shift paradigm...
Population-based study of lymphoma in Germany: rationale, study design and first resultsNikolaus Becker
Deutsches Krebsforschungszentrum, Abteilung Klinische Epidemiologie, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Leuk Res 28:713-24. 2004..The inconsistencies of some of the findings with an explanation by the Th1/Th2 paradigm, however, warrant further research and may indicate that broader explanatory concepts are needed...
Single nucleotide polymorphism--disease relationships: statistical issues for the performance of association studiesNikolaus Becker
Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, Heidelberg 69120, Germany
Mutat Res 525:11-8. 2003..Additionally, minimal information is proposed which should be presented in publications about association studies in order to facilitate reproducibility studies by other authors...
Statin use and risk of lymphoid neoplasms: results from the European Case-Control Study EPILYMPHJoan Fortuny
, , Gran Via Km 2.7, 08907 L'Hospitalet de Llobregat, Autonomous University of Barcelona [corrected] Barcelona, Catalonia, Spain
Cancer Epidemiol Biomarkers Prev 15:921-5. 2006..These results are reassuring for the increasing number of patients taking statins on a regular basis...
Exposure to ultraviolet radiation and risk of malignant lymphoma and multiple myeloma--a multicentre European case-control studyPaolo Boffetta
International Agency for Research on Cancer, Lyon, France
Int J Epidemiol 37:1080-94. 2008..Three recent studies have reported a decreased risk of non-Hodgkin lymphoma (NHL) for high ultraviolet (UV) radiation exposure...
The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysisXiang Lin Tan
Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany
Int J Cancer 122:2573-80. 2008..However, the CCND1 G870A polymorphism may modify the protective effect of postmenopausal hormone use on the development of CRC...
Personal use of hair dye and the risk of certain subtypes of non-Hodgkin lymphomaYawei Zhang
Environmental Science Division, School of Public Health, Yale University, New Haven, CT, USA
Am J Epidemiol 167:1321-31. 2008..1, 2.0). These results indicate that personal hair-dye use may play a role in risks of FL and CLL/SLL in women who started use before 1980 and that increased risk of FL among women who started use during or after 1980 cannot be excluded...
A functional TNFRSF5 gene variant is associated with risk of lymphomaChristine F Skibola
Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, CA 94720 7360, USA
Blood 111:4348-54. 2008..These results suggest that the TNFRSF5 -1C>T polymorphism may increase FL susceptibility through mechanisms that hinder cellular immune responses. Further studies are needed to explore these findings...
Occupational exposure to meat and risk of lymphoma: a multicenter case-control study from EuropeTina Moore
Department of Lifestyle, Environment and Cancer, International Agency for Research on Cancer, Lyon, France
Int J Cancer 121:2761-6. 2007..Occupational exposure to meat does not appear to represent an important risk factor of lymphoma, although an increased risk of specific types of non-Hodgkin lymphoma cannot be excluded...
Joint effect between regular use of non-steroidal anti-inflammatory drugs, variants in inflammatory genes and risk of lymphomaBirgit Hoeft
Molecular Tumour Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg, Germany
Cancer Causes Control 19:163-73. 2008..To further research in this area, we investigated the role of genetic variants in key inflammatory factors, non-steroidal anti-inflammatory drug [NSAID] use, and their joint effect in lymphomagenesis...
Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer riskSascha Abbas
Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld, 69120 Heidelberg, Germany
Breast Cancer Res 10:R31. 2008..Effect modification by serum 25-hydroxyvitamin D (25 [OH]D), the biomarker for vitamin D status in humans, has rarely been examined...
The fibroblast growth factor receptor gene Arg388 allele is not associated with early lymph node metastasis of breast cancerNikolaus Becker
Deutsches Krebsforschungszentrum, Division of Clinical Epidemiology, 69120 Heidelberg, Germany
Cancer Epidemiol Biomarkers Prev 12:582-3. 2003
Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational studySheila A Bingham
MRC Dunn Human Nutrition Unit, Cambridge, UK
Lancet 361:1496-501. 2003..INTERPRETATION: In populations with low average intake of dietary fibre, an approximate doubling of total fibre intake from foods could reduce the risk of colorectal cancer by 40%...
Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphomaWendy Cozen
Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles 90089 9175, USA
Blood 111:3377-82. 2008..8-fold (P=.03) increase in YAHL risk. Thus, both case-twins and their unaffected cotwins had a decreased ability to produce IL-12, which may contribute to YAHL susceptibility...
Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma associationAlexandra Nieters
Department of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany
Cancer 103:740-8. 2005..However, only a minority of HBV carriers eventually develop hepatocellular carcinoma. The authors hypothesized that cytokine genotypes may be important codeterminants of the risk of HBV-related hepatocellular carcinoma...
Non-Hodgkin lymphoma and obesity: a pooled analysis from the InterLymph ConsortiumEleanor V Willett
Epidemiology and Genetics Unit, Department of Health Sciences, University of York, Heslington, York YO10 5DD, United Kingdom
Int J Cancer 122:2062-70. 2008....
[Dietary fibers in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study]Anne M Tjønneland
Kraeftens Bekaempelse, Institut for Epidemiologisk Kraeftforskning, København
Ugeskr Laeger 166:2458-60. 2004
Smoking and lymphoma risk in the European prospective investigation into cancer and nutritionAlexandra Nieters
Division of Cancer Epidemiology, Deutsches Krebsforschungszentrum, Heidelberg, Germany
Am J Epidemiol 167:1081-9. 2008..Future analysis should involve viral biomarkers and genetic susceptibility markers to elucidate potential mechanisms of smoking-induced carcinogenesis, particularly for Hodgkin's lymphoma...
Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph ConsortiumNathaniel Rothman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Lancet Oncol 7:27-38. 2006..We aimed to test this hypothesis using previously unpublished data from eight European, Canadian, and US case-control studies of the International Lymphoma Epidemiology Consortium (InterLymph)...
Genetic susceptibility to lymphomaChristine F Skibola
Division of Environmental Health Sciences, School of Public Health, 140 Warren Hall, University of California, Berkeley, CA 94720 7360, USA
Haematologica 92:960-9. 2007..Numerous studies suggest that common genetic variants with low penetrance influence lymphoma risk, though replication studies will be needed to eliminate false positive associations...
Fruit and vegetable consumption and lung cancer risk: updated information from the European Prospective Investigation into Cancer and Nutrition (EPIC)Jakob Linseisen
Division of Clinical Epidemiology, German Cancer Research Centre, Heidelberg, Germany
Int J Cancer 121:1103-14. 2007..In addition to an overall inverse association with fruit intake, the results of this evaluation add evidence for a significant inverse association of vegetable consumption and lung cancer incidence in smokers...
Birth order, allergies and lymphoma risk: results of the European collaborative research project EpilymphNikolaus Becker
Division of Cancer Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, D 69120 Heidelberg, Germany
Leuk Res 31:1365-72. 2007..Our findings on birth order and lymphoma increase the inconsistency of findings across studies and suggest a critical reappraisal of potential underlying mechanisms...
Helicobacter pylori infection, interleukin-1 gene polymorphisms and the risk of colorectal cancer: evidence from a case-control study in GermanyNatalia Zumkeller
Division of Clinical Epidemiology and Aging Research, German Cancer Research Centre, Bergheimer Str 20, D 69115 Heidelberg, Germany
Eur J Cancer 43:1283-9. 2007..Additionally, a pro-inflammatory genotype did not increase the colorectal cancer risk associated with H. pylori infection. H. pylori positive subjects carrying the pro-inflammatory genotypes even had a lower risk...
Risk of malignant lymphoma following viral hepatitis infectionPierluigi Cocco
Department of Public Health, Occupational Health Section, University of Cagliari, Asse Didattico, Policlinico Universitario, SS 554, Km 4, 500, 09042, Monserrato, Cagliari, Italy
Int J Hematol 87:474-83. 2008..Our results confirm a role of either acute or chronic active HCV infection in lymphomagenesis. Further studies are warranted to test the hypothesis that acute infection from other hepatitis viruses might also increase lymphoma risk...
Diabetes and the risk of non-Hodgkin's lymphoma and multiple myeloma in the European Prospective Investigation into Cancer and NutritionAneire E Khan
Department of Epidemiology and Public Health, Division of Epidemiology, Public Health and Primary Care, Imperial College London, St Mary s Campus, Variety Wing, Norfolk Place, Paddington, London W2 1PG
Haematologica 93:842-50. 2008..Increases in the incidence of non-Hodgkin's lymphoma and multiple myeloma in the past implicate environmental factors as potential causal agents...
Variation in DNA repair genes XRCC3, XRCC4, XRCC5 and susceptibility to myelomaPatrick J Hayden
Durkan Leukaemia Laboratories, Department of Haematology, Institute of Molecular Medicine, Trinity College Dublin, Ireland
Hum Mol Genet 16:3117-27. 2007..015). This SNP is located in the 3'-UTR of XRCC5. Overall, these data provide support for the hypothesis that common variation in the genes encoding DNA repair proteins contributes to susceptibility to myeloma...
Family history of hematopoietic malignancies and risk of non-Hodgkin lymphoma (NHL): a pooled analysis of 10 211 cases and 11 905 controls from the International Lymphoma Epidemiology Consortium (InterLymph)Sophia S Wang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Blood 109:3479-88. 2007..0; 95% CI = 1.6-5.6). The pattern of NHL heritability appeared to be uniform across NHL subtypes, but risk patterns differed by specific hematopoietic malignancies and the sex of the relative, revealing critical clues to disease etiology...
Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphomaChristine F Skibola
School of Public Health, Division of Environmental Health Sciences, University of California Berkeley, Berkeley, California, USA
PLoS ONE 3:e2816. 2008..Non-Hodgkin lymphoma (NHL) is the fifth most common cancer in the U.S. and few causes have been identified. Genetic association studies may help identify environmental risk factors and enhance our understanding of disease mechanisms...
Tobacco smoking, alcohol drinking and non-Hodgkin's lymphoma: A European multicenter case-control study (Epilymph)Herve Besson
International Agency for Research on Cancer, Lyon, France
Int J Cancer 119:901-8. 2006..The results of this large-scale European study did not support an association between tobacco and NHL and suggested a protective effect of alcohol on development of NHL for men and in non-Mediterranean countries...
Reproductive and dietary determinants of the age at menopause in EPIC-HeidelbergGabriele Nagel
Division of Clinical Epidemiology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Maturitas 52:337-47. 2005..The aim of the study was to explore the influence of reproductive and dietary factors on the age at menopause...
