Research Topics
| F J de AbajoSummaryCountry: Spain Publications
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Detail Information
Publications
Risk of upper gastrointestinal tract bleeding associated with selective serotonin reuptake inhibitors and venlafaxine therapy: interaction with nonsteroidal anti-inflammatory drugs and effect of acid-suppressing agentsFrancisco J de Abajo
Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency for Medicines and Healthcare Products, Campezo 1, Madrid 28022, Spain
Arch Gen Psychiatry 65:795-803. 2008..The wide use of these drugs makes such potential risk a public health concern, and identification of factors that may increase or minimize such risk is necessary...
Antidepressants and risk of upper gastrointestinal bleedingFrancisco J de Abajo
Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency for Medicines and Healthcare Products, Madrid, Spain
Basic Clin Pharmacol Toxicol 98:304-10. 2006..The increased risk may be of particular relevance when the SSRIs are associated with NSAIDs as well as low-dose aspirin...
[Trends of non-steroidal anti-inflammatory drugs use in Spain, 1990 through 2003]F J de Abajo
División de Farmacoepidemiología y Farmacovigilancia, Agencia Española de Medicamentos y Productos Sanitarios, Ministerio de Sanidad y Consumo, Madrid, Espana
Aten Primaria 36:424-33. 2005..To know the trends of supply, consumption and pattern of use of non-steroidal anti-inflammatory drugs (NSAIDs) in Spain from 1990 through 2003, as well as their costs...
Labor induction with dinoprostone or oxytocine and postpartum disseminated intravascular coagulation: a hospital-based case-control studyFrancisco J de Abajo
Division of Pharmacoepidemiology and Pharmacovigilance, Agencia Española de Medicamentos y Productos Sanitarios, Madrid, Spain
Am J Obstet Gynecol 191:1637-43. 2004..This study was undertaken to test the hypothesis of an association between pharmacologic agents used for labor induction, in particular dinoprostone, and postpartum disseminated intravascular coagulation (DIC)...
Acute and clinically relevant drug-induced liver injury: a population based case-control studyFrancisco J de Abajo
Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Medicines Agency, Madrid, Spain
Br J Clin Pharmacol 58:71-80. 2004..To provide quantitative information about the absolute and relative risks of acute and clinically relevant drug-induced liver injury...
[Helsinki Declaration VI: a necessary revision, but sufficient?]F J de Abajo
División de Farmacoepidemiología y Farmacovigilancia Agencia Española del Medicamento Ctra Majadahonda a Pozuelo, Km 2 28220 Majadahonda, Madrid
Rev Esp Salud Publica 75:407-19. 2001..The amendment could not be put off longer. In the present paper, I analyse the main shortcomings of the Declaration before the 2000 amendment and to what extent the fifth revision has corrected them...
Risk of upper gastrointestinal bleeding and perforation associated with low-dose aspirin as plain and enteric-coated formulationsF J de Abajo
División de Farmacoepidemiología y Farmacovigilancia, Agencia Española del Medicamento, Madrid, Spain
BMC Clin Pharmacol 1:1. 2001..The coating of aspirin has been proposed as an approach to reduce such a risk. To test this hypothesis, we carried out a population based case-control study...
Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control studyF J de Abajo
División de Farmacoepidemiología y Farmacovigilancia, Agencia Española del Medicamento, 28220 Majadahonda, Madrid, Spain
BMJ 319:1106-9. 1999..To examine the association between selective serotonin reuptake inhibitors and risk of upper gastrointestinal bleeding...
Association between aspirin and upper gastrointestinal complications: systematic review of epidemiologic studiesL A Garcia Rodriguez
Centro Español de Investigación Farmacoepidemiológica, Madrid, Spain
Br J Clin Pharmacol 52:563-71. 2001..This study summarizes the relative risk (RR) for serious upper gastrointestinal complications (UGIC) associated with aspirin exposure in general and with specific aspirin doses and formulations in particular...
Risk of ventricular arrhythmias associated with nonsedating antihistamine drugsF J de Abajo
Area de Farmacovigilancia, Centro Nacional de Farmacobiologia, Madrid, Spain
Br J Clin Pharmacol 47:307-13. 1999..The effects of age, sex, dose, duration of treatment, and the interaction with P450 inhibitor drugs were also examined...
