Research Topics
| Fernando CoboSummaryCountry: Spain Publications
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Detail Information
Publications
Airborne particle monitoring in clean room environments for stem cell culturesFernando Cobo
Stem Cell Bank of Andalucia Spanish Central Node, Hospital Universitario Virgen de las Nieves, Granada, Spain
Biotechnol J 3:43-52. 2008..This should also address the regional regulatory requirements and will depend on local conditions in each processing center. Each center must evaluate its specific needs and establish appropriate monitoring procedures...
Application of methods for viral clearance in stem cell productionFernando Cobo
Stem Cell Bank of Andalucia Spanish Central Node, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, 2, 18014, Granada, Spain
In Vitro Cell Dev Biol Anim 43:371-8. 2007..In this paper, we summarize the main methods of viral clearance and we have provided an overview of the main features taking into account in the viral clearance techniques...
CNK/T-cell brain lymphoma associated with Epstein-Barr virus in a patient with AIDSFernando Cobo
Department of Pathology and Tumor Bank, Infectious Pathology Unit, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, 2, 18014 Granada, Spain
Neuropathology 27:396-402. 2007..The diagnosis of this kind of lymphomas requires a multimodality approach correlating clinical, morphological, immunophenotypic and molecular data...
The histological spectrum of non-granulomatous localized mucosal leishmaniasis caused by Leishmania infantumF Cobo
Infectious Pathology Unit, Department of Pathology, Hospital Universitario Virgen de las Nieves, Avenida Fuerzas Armadas, 2, 18014 Granada, Spain
Ann Trop Med Parasitol 101:689-94. 2007..The hope was that the information collected will help European clinicians diagnose such cases, even when amastigotes cannot be readily demonstrated...
Microbiological contamination in stem cell culturesFernando Cobo
Stem Cell Bank of Andalucia Spanish Central Node, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas 2, 18014 Granada, Spain
Cell Biol Int 31:991-5. 2007....
Environmental microbial contamination in a stem cell bankF Cobo
Stem Cell Bank of Andalucia Spanish Central Node, Hospital Universitario Virgen de las Nieves, Granada, Spain
Lett Appl Microbiol 44:379-86. 2007..The aim of this study was to evaluate the main environmental microbial contaminants of the clean rooms in our stem cell bank...
Electron microscopy reveals the presence of viruses in mouse embryonic fibroblasts but neither in human embryonic fibroblasts nor in human mesenchymal cells used for hESC maintenance: toward an implementation of microbiological quality assurance program iFernando Cobo
Stem Cell Bank of Andalucia Spanish Central Node, Centro de Investigaciones Biomedicas, Parque Tecnológico de las Ciencias de la Salud, Granada, Spain
Cloning Stem Cells 10:65-74. 2008....
Diffuse large B-cell lymphoma in a renal allograft associated with Epstein-Barr virus in the recipient: a case report and a review of lymphomas presenting in a transplanted kidneyFernando Cobo
Infectious Pathology Unit, Department of Pathology and Tissue and Tumor Bank, Hospital Universitario Virgen de las Nieves, Granada, Spain
Clin Transplant 22:512-9. 2008..Health care providers should be aware of this clinical entity and heightened index of suspicion should be used so as not to delay diagnosis and not to lose the allograft...
Review article: relationship of human papillomavirus with papillary squamous cell carcinoma of the upper aerodigestive tract: a reviewFernando Cobo
Infectious Pathology Unit, Department of Pathology and Tumour and Tissue Bank, Hospital Universitario Virgen de las Nieves, Granada, Spain
Int J Surg Pathol 16:127-36. 2008..This association should be clearly established to make a correct diagnosis and propose the best therapeutic strategies, such as new vaccines...
Evaluation of a laser technique to isolate the inner cell mass of murine blastocystsJose Luis Cortes
Andalusian Stem Cell Bank Spanish Central Node, Centro de Investigaciones Biomedicas, Parque Tecnológico de las Ciencias de la Salud, Avenida del Conocimiento s n, Granada, Spain
Biotechnol Appl Biochem 46:205-9. 2007....
Environmental monitoring in stem cell banksFernando Cobo
Stem Cell Bank of Andalucia Spanish Central Node, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas 2, 18014, Granada, Spain
Appl Microbiol Biotechnol 70:651-62. 2006..Each centre will need to evaluate its specific needs and establish appropriate monitoring procedures which should not become intrusive to the extent that they might compromise the quality of the cell banks or products...
Role of the embryology laboratory in the human embryonic stem cell line derivation processJose Luis Cortes
Andalusian Stem Cell Bank Spanish Central Node, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, 2, 18014, Granada, Spain
Cytotechnology 52:1-11. 2006....
Diagnostic approaches for viruses and prions in stem cell banksFernando Cobo
Stem Cell Bank of Andalucia Spanish Central Node, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, 2, 18014 Granada, Spain
Virology 347:1-10. 2006....
Conventional and molecular cytogenetic diagnostic methods in stem cell research: a concise reviewPurificación Catalina
Andalusian Stem Cell Bank Bancelán, Instituto de Investigaciones Biomedicas, Parque Tecnológico de la Salud, Avda del Conocimiento s n, 18014 Granada, Spain
Cell Biol Int 31:861-9. 2007..Thus, it is crucial to optimize and validate their use in the determination of the chromosomal stability of these stem cell lines, and assess the advantages and limitations of these cutting-edge cytogenetic technologies...
Microbiological control in stem cell banks: approaches to standardisationFernando Cobo
Stem Cell Bank of Andalucia Spanish Central Node, Hospital Universitario Virgen de las Nieves, Avda Fuerzas Armadas, 2, 18014, Granada, Spain
Appl Microbiol Biotechnol 68:456-66. 2005..Stem cell lines should be tested for prion particles and a virus of animal origin that assure an acceptable quality...
Localized mucosal leishmaniasis due to Leishmania (Leishmania) infantum: clinical and microbiologic findings in 31 patientsLuis Aliaga
Infectious Diseases Unit, Hospital Universitario Virgen de las Nieves, Granada, Spain
Medicine (Baltimore) 82:147-58. 2003..The treatment of choice for these patients is not established yet, but most patients respond to antimonial compounds given for 28 days or less...
Whole-blastocyst culture followed by laser drilling technology enhances the efficiency of inner cell mass isolation and embryonic stem cell derivation from good- and poor-quality mouse embryos: new insights for derivation of human embryonic stem cell lineJ L Cortes
Spanish Stem Cell Bank Andalusian Branch, University of Granada, Instituto de Investigaciones Biomedicas, Parque Tecnológico de la Salud, Avda del Conocimiento s n, Granada, Spain
Stem Cells Dev 17:255-67. 2008..This methodology may open up new avenues for further improvements for the derivation of hES cells, the majority of which are derived from frozen, poor-quality human embryos...
The low rate of HLA class I molecules on the human embryonic stem cell line HS293 is associated with the APM components' expression levelC M Cabrera
Stem Cell Bank of Andalucia Spanish Central Node, Hospital Universitario Virgen de las Nieves, Granada, Spain
Cell Biol Int 31:1072-8. 2007..We described for the first time in this report that the hESCs shared similar mechanisms with respect to tumor cells responsible for the weak HLA class I expression on the cell surface...
Effect of mitomycin-C on human foreskin fibroblasts used as feeders in human embryonic stem cells: immunocytochemistry MIB1 score and DNA ploidy and apoptosis evaluated by flow cytometryA Nieto
Andalucia Stem Cell Bank, Cell Culture, Hospital Universitario Virgen de las Nieves, Edificio de Gobierno 4, Avda Fuerzas Armadas 2, 18014 Granada, Spain
Cell Biol Int 31:269-78. 2007..The percentage of apoptotic cells increased from day 2 to day 10, at the same time as the necrotic ones increased. The HS181 hESC line grew in an undifferentiated state on inactive HFF throughout the study...
Embryonic stem cell bank: a work proposalA Nieto
Andalusian Stem Cells, Andalusian Stem Cell, Bank, Granada, Spain
Stem Cell Rev 2:117-26. 2006....
Strategies for preventing immunologic rejection of transplanted human embryonic stem cellsC M Cabrera
Stem Cell Bank of Andalucia Spanish Central Node, Hospital Universitario Virgen de las Nieves, Granada, Spain
Cytotherapy 8:517-8. 2006....
Human Papillomavirus (HPV) Type Distribution in Females with Abnormal Cervical Cytology. A Correlation with Histological StudyFernando Cobo
Infectious Pathology Unit, Department of Pathology, Hospital Universitario Virgen de las Nieves, Granada, Spain
Open Virol J 3:60-6. 2009....
General safety guidances in stem cell bank installationsF Cobo
, Hospital Universitario Virgen de las Nieves, Granada, Spain
Cytotherapy 8:47-56. 2006..Different types of safety measurements should be distinguished and secured, for example for protection of personnel, protection of the cell cultures and protection in general of humans and the environment...
Application of microarray technology for microbial diagnosis in stem cell cultures: a reviewF Cobo
Stem Cell Bank of Andalucia Spanish Central Node, Granada, Spain fernando cobo sspa2juntadeandalucia es
Cytotherapy 9:53-9. 2007....
Spanish stem cell bank interviews examine the interest of couples in donating surplus human IVF embryos for stem cell researchJose Luis Cortes
Cell Stem Cell 1:17-20. 2007
The development of 'feeder' cells for the preparation of clinical grade hES cell lines: challenges and solutionsGlyn N Stacey
Division of Cell Biology and Imaging and UK Stem Cell Bank, National Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire EN6 3QG, United Kingdom
J Biotechnol 125:583-8. 2006....
