Simon Mendez-Ferrer

Summary

Affiliation: Centro Nacional de Investigaciones Cardiovasculares
Country: Spain

Publications

  1. pmc Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    Simon Mendez-Ferrer
    Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Nature 466:829-34. 2010
  2. pmc Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
    Andrew Chow
    Department of Gene and Cell Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Exp Med 208:261-71. 2011
  3. doi request reprint Haematopoietic stem cell release is regulated by circadian oscillations
    Simon Mendez-Ferrer
    Mount Sinai School of Medicine, Department of Medicine and Department of Gene and Cell Medicine, New York, New York 10029, USA
    Nature 452:442-7. 2008
  4. pmc Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields
    Daniel Lucas
    Ruth L and David S Gottesman Institute for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, New York, NY 10461, USA
    Blood 119:3962-5. 2012
  5. doi request reprint Cooperation of beta(2)- and beta(3)-adrenergic receptors in hematopoietic progenitor cell mobilization
    Simon Mendez-Ferrer
    Medicine, Tisch Cancer Institute, Mount Sinai School of Medicine, New York, New York, USA
    Ann N Y Acad Sci 1192:139-44. 2010
  6. doi request reprint Circadian rhythms influence hematopoietic stem cells
    Simon Mendez-Ferrer
    Department of Medicine, USA bDepartment of Gene and Cell Medicine, USA
    Curr Opin Hematol 16:235-42. 2009
  7. pmc Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands
    Chao Shi
    Immunology Program, Sloan Kettering Institute, Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Immunity 34:590-601. 2011
  8. ncbi request reprint Hematopoietic stem cell trafficking: regulated adhesion and attraction to bone marrow microenvironment
    Simon Mendez-Ferrer
    Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Ann N Y Acad Sci 1116:392-413. 2007
  9. ncbi request reprint Resident progenitors and bone marrow stem cells in myocardial renewal and repair
    Simon Mendez-Ferrer
    Cardiovascular Institute and Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, NY 10029, USA
    Nat Clin Pract Cardiovasc Med 3:S83-9. 2006
  10. doi request reprint Galpha(s) uncouples hematopoietic stem cell homing and mobilization
    Simon Mendez-Ferrer
    Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Cell Stem Cell 4:379-80. 2009

Collaborators

Detail Information

Publications10

  1. pmc Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    Simon Mendez-Ferrer
    Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
    Nature 466:829-34. 2010
    ..These results uncover an unprecedented partnership between two distinct somatic stem-cell types and are indicative of a unique niche in the bone marrow made of heterotypic stem-cell pairs...
  2. pmc Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
    Andrew Chow
    Department of Gene and Cell Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Exp Med 208:261-71. 2011
    ..Thus, strategies that target BM MΦ hold the potential to augment stem cell yields in patients that mobilize HSCs/progenitors poorly...
  3. doi request reprint Haematopoietic stem cell release is regulated by circadian oscillations
    Simon Mendez-Ferrer
    Mount Sinai School of Medicine, Department of Medicine and Department of Gene and Cell Medicine, New York, New York 10029, USA
    Nature 452:442-7. 2008
    ..These data indicate that a circadian, neurally driven release of HSC during the animal's resting period may promote the regeneration of the stem cell niche and possibly other tissues...
  4. pmc Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields
    Daniel Lucas
    Ruth L and David S Gottesman Institute for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, New York, NY 10461, USA
    Blood 119:3962-5. 2012
    ..Therefore, these data suggest that blockade of NE reuptake may be a novel therapeutic target to increase stem cell yield in patients...
  5. doi request reprint Cooperation of beta(2)- and beta(3)-adrenergic receptors in hematopoietic progenitor cell mobilization
    Simon Mendez-Ferrer
    Medicine, Tisch Cancer Institute, Mount Sinai School of Medicine, New York, New York, USA
    Ann N Y Acad Sci 1192:139-44. 2010
    ..Double deficiency in beta(2)- and beta(3)-ARs compromises enforced mobilization. Therefore, beta(2)- and beta(3)-ARs have specific roles in stromal cells and cooperate during progenitor mobilization...
  6. doi request reprint Circadian rhythms influence hematopoietic stem cells
    Simon Mendez-Ferrer
    Department of Medicine, USA bDepartment of Gene and Cell Medicine, USA
    Curr Opin Hematol 16:235-42. 2009
    ..There is increasing evidence showing the impact of biological rhythms on the traffic of hematopoietic stem cells (HSCs) and their proliferation and differentiation capacities...
  7. pmc Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands
    Chao Shi
    Immunology Program, Sloan Kettering Institute, Infectious Diseases Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    Immunity 34:590-601. 2011
    ..Our findings suggest that bone marrow MSCs and CAR cells respond to circulating microbial molecules and regulate bloodstream monocyte frequencies by secreting MCP1 in proximity to bone marrow vascular sinuses...
  8. ncbi request reprint Hematopoietic stem cell trafficking: regulated adhesion and attraction to bone marrow microenvironment
    Simon Mendez-Ferrer
    Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Ann N Y Acad Sci 1116:392-413. 2007
    ..Recent studies suggest that G-CSF-mediated suppression requires signals from the sympathetic nervous system (SNS). This review summarizes emerging concepts thought to contribute to stem cell migration...
  9. ncbi request reprint Resident progenitors and bone marrow stem cells in myocardial renewal and repair
    Simon Mendez-Ferrer
    Cardiovascular Institute and Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, NY 10029, USA
    Nat Clin Pract Cardiovasc Med 3:S83-9. 2006
    ..Here, we briefly review the use of bone-marrow-derived and cardiac-derived stem/progenitor cells in myocardial regeneration studies and discuss their significance for the future of the field of myocardial regeneration...
  10. doi request reprint Galpha(s) uncouples hematopoietic stem cell homing and mobilization
    Simon Mendez-Ferrer
    Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Cell Stem Cell 4:379-80. 2009
    ..In a recent publication in Nature, Adams et al. (2009) demonstrate that the guanine-nucleotide-binding stimulatory alpha subunit (Galpha(s)) can, unexpectedly, promote both phenomena...