Research Topics
| Fátima GebauerSummaryAffiliation: Center for Genomic Regulation Country: Spain Publications
| Collaborators
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Detail Information
Publications
Molecular mechanisms of translational controlFátima Gebauer
Centre de Regulacio Genomica, Passeig Maritim 37 49, 08003 Barcelona, Spain
Nat Rev Mol Cell Biol 5:827-35. 2004..Instead of providing a comprehensive account of the examples that are known at present, we discuss instructive cases that serve as paradigms for different modes of translational control...
From cis-regulatory elements to complex RNPs and backFátima Gebauer
Gene Regulation Programme, Centre for Genomic Regulation CRG and UPF, 08003 Barcelona, Spain
Cold Spring Harb Perspect Biol 4:a012245. 2012..It also highlights recent technical advances that have ushered in the era of transcriptome-wide studies of the ribonucleoprotein complexes formed by mRNAs and their trans-acting factors...
Cytoplasmic polyadenylation and translational controlAna Villalba
Gene Regulation Programme, Centre for Genomic Regulation CRG and UPF, Dr Aiguader 88, 08003 Barcelona, Spain
Curr Opin Genet Dev 21:452-7. 2011..These observations underscore the versatility of CPEB as a translational regulator, and highlight the diversity of cytoplasmic polyadenylation mechanisms...
Widespread generation of alternative UTRs contributes to sex-specific RNA binding by UNRMarija Mihailovic
Gene Regulation Programme, Centre for Genomic Regulation CRG and UPF, 08003 Barcelona, Spain
RNA 18:53-64. 2012..These results suggest that UNR exploits the transcript diversity generated by alternative processing and alternative promoter usage to bind and regulate target genes in a sex-specific manner...
miR-181a regulates cap-dependent translation of p27(kip1) mRNA in myeloid cellsRafael Cuesta
Centre de Regulació Genòmica CRG UPF, Gene Regulation Programme, Dr Aiguader 88, 08003 Barcelona, Spain
Mol Cell Biol 29:2841-51. 2009..These results identify miR-181a as a regulator of p27 mRNA translation during myeloid cell differentiation...
Drosophila UNR is required for translational repression of male-specific lethal 2 mRNA during regulation of X-chromosome dosage compensationIrina Abaza
Centre de Regulació Genòmica CRG UPF, 08003 Barcelona, Spain
Genes Dev 20:380-9. 2006..These data identify a novel regulator of dosage compensation in Drosophila that acts coordinately with SXL in translational control...
Functional domains of Drosophila UNR in translational controlIrina Abaza
Centre de Regulació Genòmica CRG UPF, Gene Regulation Programme, 08003 Barcelona, Spain
RNA 14:482-90. 2008..Our results identify domains and residues required for UNR function in translational control...
Trading translation with RNA-binding proteinsIrina Abaza
Centre de Regulacio Genomica, Gene Regulation Programme, 08003 Barcelona, Spain
RNA 14:404-9. 2008..This review summarizes the available information on molecular mechanisms of translational repression by RNA-binding proteins. By using a specific set of well-defined examples, we also describe how regulation can be reversed...
