Research Topics
| Xavier CastellsagueSummaryCountry: Spain Publications
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Detail Information
Publications
Worldwide human papillomavirus etiology of cervical adenocarcinoma and its cofactors: implications for screening and preventionXavier Castellsague
Institut d Investigacio Biomedica de Bellvitge, Cancer Epidemiology and Registration Unit, Institut Català d Oncologia L Hospitalet de Llobregat, Barcelona, Spain
J Natl Cancer Inst 98:303-15. 2006..The extent to which human papillomavirus (HPV) infection and cofactors may explain this differential trend is unclear...
Independent and joint effects of tobacco smoking and alcohol drinking on the risk of esophageal cancer in men and womenX Castellsague
Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, L Hospitalet de Llobregat, Barcelona, Spain
Int J Cancer 82:657-64. 1999..The overall public-health implications of these findings are obvious for a tumor that depends on preventive strategies for its control...
Smoking and drinking cessation and risk of esophageal cancer (Spain)X Castellsague
Institut Catala d Oncologia, Servei d Epidemiologia i Registre del Cancer, L Hospitalet de Llobregat Barcelona, Spain
Cancer Causes Control 11:813-8. 2000..To explore the effectiveness of alcohol drinking and tobacco smoking cessation in reducing esophageal cancer risk, taking into account the key characteristics of each habit and the simultaneous exposure to both habits...
Male circumcision, penile human papillomavirus infection, and cervical cancer in female partnersXavier Castellsague
Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, Hospitalet de Llobregat, Barcelona, Spain
N Engl J Med 346:1105-12. 2002..It is uncertain whether male circumcision reduces the risks of penile human papillomavirus (HPV) infection in the man and of cervical cancer in his female partner...
Environmental co-factors in HPV carcinogenesisXavier Castellsague
Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, Gran Vias n km 2, 7 08907 L Hospitalet de Llobregat, Barcelona, Spain
Virus Res 89:191-9. 2002....
Chlamydia trachomatis infection in female partners of circumcised and uncircumcised adult menXavier Castellsague
Cancer Epidemiology and Registration Unit, Institut d Investigacio Biomedica de Bellvitge, Institut Catala d Oncologia, L Hospitalet de Llobregat, Barcelona, Spain
Am J Epidemiol 162:907-16. 2005..These findings suggest that male circumcision could reduce the risk of C. trachomatis infection in female sexual partners...
The male role in cervical cancerXavier Castellsague
Institut Catala d Oncologia, Servel d Epidemiologia I Registre del Càncer, Gran Via s n, Km 2 7, 08907 L Hospitalet de Llobregat, Barcelona, Spain
Salud Publica Mex 45:S345-53. 2003..More research is needed to better understand the natural history and epidemiology of HPV infections in men. This paper is available too at: http://www.insp.mx/salud/index.html...
Intrauterine device use, cervical infection with human papillomavirus, and risk of cervical cancer: a pooled analysis of 26 epidemiological studiesXavier Castellsague
Unit of Infections and Cancer, Cancer Epidemiology Research Program, Institut Catala d Oncologia, Bellvitge Biomedical Research Institute, L Hospitalet de Llobregat, Catalonia, Spain
Lancet Oncol 12:1023-31. 2011..We assessed whether IUD use affects cervical human papillomavirus (HPV) infection and the risk of developing cervical cancer...
Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide studySilvia de Sanjose
IDIBELL, Institut Català d Oncologia Catalan Institute of Oncology, L Hospitalet de Llobregat, Barcelona, Spain
Lancet Oncol 11:1048-56. 2010..We aimed to provide novel and comprehensive data about the worldwide genotype distribution in patients with invasive cervical cancer...
Predictors of human papillomavirus infection in women undergoing routine cervical cancer screening in Spain: the CLEOPATRE studyEsther Roura
Cancer Epidemiology Research Program, Institut Català d Oncologia IDIBELL, CIBER ESP, RTICC, L Hospitalet de Llobregat, Barcelona, Catalonia, Spain
BMC Infect Dis 12:145. 2012..The aim of the current study was to investigate socio-demographic, lifestyle, and medical factors for potential associations with cervical HPV infection in women undergoing cervical cancer screening in Spain...
Cervical human papillomavirus prevalence in 5 continents: meta-analysis of 1 million women with normal cytological findingsLaia Bruni
Unit of Infections and Cancer, Cancer Epidemiology Research Program, IDIBELL Institut Català d Oncologia, Barcelona, Spain
J Infect Dis 202:1789-99. 2010..Baseline information on human papillomavirus (HPV) prevalence and type distribution is highly desirable to evaluate the impact of prophylactic HPV vaccines in the near future...
Human Papillomavirus (HPV) infection in pregnant women and mother-to-child transmission of genital HPV genotypes: a prospective study in SpainXavier Castellsague
Unit of Infections and Cancer UNIC, Cancer Epidemiology Research Program CERP, IDIBELL Institut Català d Oncologia ICO, Hospitalet de Llobregat, Barcelona, Spain
BMC Infect Dis 9:74. 2009..Studies on HPV infection in pregnant women and HPV transmission to the child have yielded inconsistent results...
Prevalence and genotype distribution of human papillomavirus infection of the cervix in Spain: the CLEOPATRE studyXavier Castellsague
Cancer Epidemiology Research Program, Catalan Institute of Oncology IDIBELL, CIBER ESP, L Hospitalet de Llobregat, Spain
J Med Virol 84:947-56. 2012..The high prevalence of HPV infection among young women may reflect recent changes in sexual behavior...
Epidemiology and costs of screening and management of precancerous lesions of the cervix in SpainXavier Castellsague
Cancer Epidemiology Research Program, Institut Catala d Oncologia, IDIBELL, CIBERESP, L Hospitalet de Llobregat, Catalonia, Spain
J Low Genit Tract Dis 13:38-45. 2009..Screening prevents cancer by detecting precancerous lesions (cervical intraepithelial neoplasia, CIN). Our aim was to assess the annual number of Pap smears and CIN diagnoses in Spain and to estimate associated management costs...
Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysisSilvia de Sanjose
Servei d Epidemiologia i Registre del Cancer, Institut Catala d Oncologia, Barcelona, Spain
Lancet Infect Dis 7:453-9. 2007..The HPV types most commonly detected are similar to those most commonly described in pre-neoplastic and cancer cases, although the relative contribution of HPV16 and HPV18 is substantially lower in cytologically normal women...
Vaccine-related HPV genotypes in women with and without cervical cancer in Mozambique: burden and potential for preventionXavier Castellsague
IDIBELL, Institut Català d Oncologia ICO, L Hospitalet de Llobregat, Barcelona, Spain
Int J Cancer 122:1901-4. 2008..The introduction of an efficacious HPV 16/18 vaccine could potentially prevent the occurrence of 72% of cervical cancer cases and up to 81% of the cases if full cross-protection against HPVs 31 and 45 is assumed...
The role of type of tobacco and type of alcoholic beverage in oral carcinogenesisXavier Castellsague
Institut Catala d Oncologia, Servei d Epidemiologia i Registre del Cancer, L Hospitalet de Llobregat, Barcelona, Spain
Int J Cancer 108:741-9. 2004..These results underline the importance of type of tobacco and alcohol concentration in oral carcinogenesis...
Human papillomavirus genotype distribution in cervical cancer cases in Spain. Implications for preventionLaia Alemany
IDIBELL, Institut Català d Oncologia Catalan Institute of Oncology, L Hospitalet de Llobregat, Barcelona, Spain
Gynecol Oncol 124:512-7. 2012..Human papillomavirus (HPV) genotype distribution in invasive cervical cancer (ICC) is critical to guide the introduction and to assess the impact of HPV prophylactic vaccines. This study aims to provide specific information for Spain...
Human papillomavirus vaccines and vaccine implementationSilvia de Sanjose
Unit of Infections and Cancer UNIC, Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL and CIBER Epidemiología y Salud Pública CIBERESP, Barcelona, Spain
Womens Health (Lond Engl) 4:595-604. 2008..Finally, some major aspects that are likely to impact the introduction of these vaccines around the world are outlined, with particular emphasis on developing countries...
Male circumcision and genital human papillomavirus: a systematic review and meta-analysisGinesa Albero
Unit of Infections and Cancer, Cancer Epidemiology Research Program, Institut Català d Oncologia Catalan Institute of Oncology, L Hospitalet de Llobregat, Barcelona, Spain
Sex Transm Dis 39:104-13. 2012..The purpose of this study was to conduct a systematic review of the literature to assess the association between MC and genital HPV infection indicators including genital warts...
High prevalence of human papillomavirus infection in the female population of GuatemalaXavier Valles
Institut Catala d Oncologia, IDIBELL, L Hospitalet de Llobregat, Barcelona, Spain
Int J Cancer 125:1161-7. 2009..HPV and abnormal cytology prevalence is high among women in Guatemala. The introduction of a HPV vaccination program would prevent an important fraction of HPV-related disease burden...
HPV vaccination against cervical cancer in women above 25 years of age: key considerations and current perspectivesXavier Castellsague
Cancer Epidemiology Research Program, Institut Catala d Oncologia, IDIBELL, CIBER ESP, Barcelona, Spain
Gynecol Oncol 115:S15-23. 2009..We consider oncogenic HPV infection and the risk of developing cervical cancer in women over 25 years of age and whether they would also benefit from vaccination against HPV...
Epidemiologic classification of human papillomavirus types associated with cervical cancerNubia Munoz
International Agency for Research on Cancer, Lyons, France
N Engl J Med 348:518-27. 2003..Infection with human papilloma virus (HPV) is the main cause of cervical cancer, but the risk associated with the various HPV types has not been adequately assessed...
Against which human papillomavirus types shall we vaccinate and screen? The international perspectiveNubia Munoz
International Agency for Research on Cancer, Lyon, France
Int J Cancer 111:278-85. 2004..The impact of modifying the number of types in the screening cocktail tests would be small and probably irrelevant for screening programs...
Resource consumption and costs of palliative care services in Spain: a multicenter prospective studyXavier Gómez-Batiste
Palliative Care Service X G B, A T, E C, J P S, J E, and Cancer Epidemiology Unit X C, Institut Catala d Oncologia, Barcelona, Spain
J Pain Symptom Manage 31:522-32. 2006..6%; P=0.001), and an increase in programmed care. Compared to the previous resource consumption and expenditure study in 1992, the current PCS policy implies a cost saving of 61%, with greater efficiency and no compromise of patient care...
The prospects of HPV vaccination in cervical cancer prevention: results of a new independent trialF Xavier Bosch
Cancer Epidemiology Research Program CERP, Catalan Institute of Oncology Institut Català d Oncologia ICO and Bellvitge Biomedical Research Institute, Avenida Gran Via 199 203, L Hospitalet de Llobregat, Barcelona, Spain
Cancer Discov 1:377-80. 2011....
The role of diet and nutrition in cervical carcinogenesis: a review of recent evidenceReina Garcia-Closas
Cancer Epidemiology and Registration Unit, Institut Català d Oncologia ICO, L Hospitalet de Llobregat, Barcelona, Spain
Int J Cancer 117:629-37. 2005..Large cohort studies are needed to adequately assess the role of foods and nutrients in cervical HPV carcinogenesis...
Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition studyCarlos A Gonzalez
Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology, Barcelona, Spain
Int J Cancer 129:449-59. 2011..None of the dietary factors examined was associated with CIS. Our study suggests a possible protective role of fruit intake and other dietary factors on ISC that need to be confirmed on a larger number of ISC cases...
Male circumcision and prevalence of genital human papillomavirus infection in men: a multinational studyGinesa Albero
Unit of Infections and Cancer UNIC, Cancer Epidemiology Research Program CERP, Catalan Institute of Oncology ICO, L Hospitalet de Llobregat 08908, Barcelona, Spain
BMC Infect Dis 13:18. 2013..The purpose of this study was to assess the association between MC and genital HPV infection in men in a large multinational study...
Effect of a 3-step critical pathway to reduce duration of intravenous antibiotic therapy and length of stay in community-acquired pneumonia: a randomized controlled trialJordi Carratala
Infectious Disease Service, Bellvitge Institute for Biomedical Research IDIBELL Hospital Universitari de Bellvitge, University of Barcelona, L Hospitalet, Barcelona, Spain
Arch Intern Med 172:922-8. 2012..We aimed to determine whether the use of a 3-step critical pathway is safe and effective in reducing duration of intravenous antibiotic therapy and length of stay in hospitalized patients with CAP...
Epidemiology and cost of treatment of genital warts in SpainXavier Castellsague
Cancer Epidemiology Research Program, Institut Catala d Oncologia, IDIBELL, CIBERESP, L Hospitalet de Llobregat, Spain
Eur J Public Health 19:106-10. 2009..Ninety percent of GW are due to Human Papillomavirus (HPV) types 6 and 11. The objective of this study was to assess the epidemiology and management costs associated with GW in Spain...
p53 and p21 Expression levels predict organ preservation and survival in invasive bladder carcinoma treated with a combined-modality approachXavier Garcia del Muro
Department of Medical Oncology, Institut Catala d Oncologia, Barcelona, Spain
Cancer 100:1859-67. 2004....
