Xavier Castells

Summary

Country: Spain

Publications

  1. ncbi request reprint Efficacy of central nervous system stimulant treatment for cocaine dependence: a systematic review and meta-analysis of randomized controlled clinical trials
    Xavier Castells
    Psychiatry Service, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Catalonia, Spain
    Addiction 102:1871-87. 2007
  2. doi request reprint Efficacy of opiate maintenance therapy and adjunctive interventions for opioid dependence with comorbid cocaine use disorders: A systematic review and meta-analysis of controlled clinical trials
    Xavier Castells
    Psychiatry Department, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
    Am J Drug Alcohol Abuse 35:339-49. 2009
  3. doi request reprint Discrete-event simulation applied to analysis of waiting lists. Evaluation of a prioritization system for cataract surgery
    Mercè Comas
    Evaluation and Clinical Epidemiology Department, Hospital del Mar IMAS, Barcelona, Spain
    Value Health 11:1203-13. 2008
  4. doi request reprint Efficacy of methylphenidate for adults with attention-deficit hyperactivity disorder: a meta-regression analysis
    Xavier Castells
    Psychiatry Department, Hospital Universitari Vall dHebron, Barcelona, Spain
    CNS Drugs 25:157-69. 2011
  5. doi request reprint Development of a predictor for human brain tumors based on gene expression values obtained from two types of microarray technologies
    Xavier Castells
    Grup d Aplicacions Biomèdiques de la RMN GABRMN, Facultat de Biociencies, Universitat Autonoma de Barcelona, Cerdanyola del Valles, Barcelona, Spain
    OMICS 14:157-64. 2010
  6. doi request reprint The psychological impact of a false-positive screening mammogram in Barcelona
    Rebecca Espasa
    Servei d Epidemiologia i Avaluació, Hospital del Mar Parc de Salut Mar, Passeig Maritim, 25 29, 08003, Barcelona, Spain
    J Cancer Educ 27:780-5. 2012
  7. pmc Cost-effectiveness of early detection of breast cancer in Catalonia (Spain)
    Misericordia Carles
    Basic Medical Sciences Department, Biomedical Research Institut of Lleida IRBLLEIDA University of Lleida, Catalonia, Spain
    BMC Cancer 11:192. 2011
  8. pmc Cost-effectiveness and harm-benefit analyses of risk-based screening strategies for breast cancer
    Ester Vilaprinyo
    Basic Medical Sciences Department, Biomedical Research Institut of Lleida IRBLLEIDA, Lleida, Catalonia, Spain Basic Medical Sciences Department, University of Lleida, Lleida, Catalonia, Spain
    PLoS ONE 9:e86858. 2014
  9. doi request reprint Factors affecting 5- and 10-year survival of women with breast cancer: an analysis based on a public general hospital in Barcelona
    Francesc Maciá
    Department of Epidemiology and Evaluation, Hospital del Mar, Barcelona, Spain
    Cancer Epidemiol 36:554-9. 2012
  10. pmc Hospital costs of nosocomial multi-drug resistant Pseudomonas aeruginosa acquisition
    Eva Morales
    Health Services Evaluation and Clinical Epidemiology Department, Hospital del Mar IMIM, Barcelona, Spain
    BMC Health Serv Res 12:122. 2012

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Efficacy of central nervous system stimulant treatment for cocaine dependence: a systematic review and meta-analysis of randomized controlled clinical trials
    Xavier Castells
    Psychiatry Service, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Barcelona, Catalonia, Spain
    Addiction 102:1871-87. 2007
    ..To evaluate the efficacy of central nervous system (CNS) stimulants compared with placebo for the treatment of cocaine dependence...
  2. doi request reprint Efficacy of opiate maintenance therapy and adjunctive interventions for opioid dependence with comorbid cocaine use disorders: A systematic review and meta-analysis of controlled clinical trials
    Xavier Castells
    Psychiatry Department, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
    Am J Drug Alcohol Abuse 35:339-49. 2009
    ..To determine the efficacy of Opiate Maintenance Therapy (OMT) and adjunctive interventions for dual heroin and cocaine dependence by means of a meta-analysis...
  3. doi request reprint Discrete-event simulation applied to analysis of waiting lists. Evaluation of a prioritization system for cataract surgery
    Mercè Comas
    Evaluation and Clinical Epidemiology Department, Hospital del Mar IMAS, Barcelona, Spain
    Value Health 11:1203-13. 2008
    ....
  4. doi request reprint Efficacy of methylphenidate for adults with attention-deficit hyperactivity disorder: a meta-regression analysis
    Xavier Castells
    Psychiatry Department, Hospital Universitari Vall dHebron, Barcelona, Spain
    CNS Drugs 25:157-69. 2011
    ..The reasons for this variability have not been comprehensively investigated...
  5. doi request reprint Development of a predictor for human brain tumors based on gene expression values obtained from two types of microarray technologies
    Xavier Castells
    Grup d Aplicacions Biomèdiques de la RMN GABRMN, Facultat de Biociencies, Universitat Autonoma de Barcelona, Cerdanyola del Valles, Barcelona, Spain
    OMICS 14:157-64. 2010
    ..At any rate, this study paves the way for further application of gene signatures to more stringent biopsy discrimination challenges...
  6. doi request reprint The psychological impact of a false-positive screening mammogram in Barcelona
    Rebecca Espasa
    Servei d Epidemiologia i Avaluació, Hospital del Mar Parc de Salut Mar, Passeig Maritim, 25 29, 08003, Barcelona, Spain
    J Cancer Educ 27:780-5. 2012
    ..In conclusion, although the women showed no psychological morbidity, there is a substantial psychological response in those with an abnormal screening mammogram...
  7. pmc Cost-effectiveness of early detection of breast cancer in Catalonia (Spain)
    Misericordia Carles
    Basic Medical Sciences Department, Biomedical Research Institut of Lleida IRBLLEIDA University of Lleida, Catalonia, Spain
    BMC Cancer 11:192. 2011
    ..We performed an economic evaluation of 20 screening strategies taking into account the cost over time of screening and subsequent medical costs, including diagnostic confirmation, initial treatment, follow-up and advanced care...
  8. pmc Cost-effectiveness and harm-benefit analyses of risk-based screening strategies for breast cancer
    Ester Vilaprinyo
    Basic Medical Sciences Department, Biomedical Research Institut of Lleida IRBLLEIDA, Lleida, Catalonia, Spain Basic Medical Sciences Department, University of Lleida, Lleida, Catalonia, Spain
    PLoS ONE 9:e86858. 2014
    ..Risk-based strategies can reduce harm and costs. It is necessary to develop accurate measures of individual risk and to work on how to implement risk-based screening strategies. ..
  9. doi request reprint Factors affecting 5- and 10-year survival of women with breast cancer: an analysis based on a public general hospital in Barcelona
    Francesc Maciá
    Department of Epidemiology and Evaluation, Hospital del Mar, Barcelona, Spain
    Cancer Epidemiol 36:554-9. 2012
    ..Data from a long-established hospital-based cancer registry were used to analyse the relationship between clinical and organisational factors and disease-specific survival among women with primary breast cancer...
  10. pmc Hospital costs of nosocomial multi-drug resistant Pseudomonas aeruginosa acquisition
    Eva Morales
    Health Services Evaluation and Clinical Epidemiology Department, Hospital del Mar IMIM, Barcelona, Spain
    BMC Health Serv Res 12:122. 2012
    ..We aimed to assess the hospital economic costs of nosocomial multi-drug resistant Pseudomonas aeruginosa acquisition...
  11. doi request reprint Patient classification systems and hospital costs of care for knee replacement in 10 European countries
    Francesc Cots
    Epidemiology and Evaluation Department, IMIM Hospital del Mar Research Institute, Barcelona, Spain
    Health Econ 21:116-28. 2012
    ..Findings suggest that DRG systems could be enhanced either by the inclusion of patient-level variables, by the use of measures of clinical outcome or by improving cost and administrative information...
  12. doi request reprint Effect of false-positive results on reattendance at breast cancer screening programmes in Spain
    Dolores Alamo-Junquera
    Servei d Epidemiologia i Avaluació Hospital del Mar Parc de Salut Mar, Barcelona, Spain
    Eur J Public Health 22:404-8. 2012
    ..The aim of this study was to examine the effect of a false-positive screening mammogram and women's characteristics on reattendance in eight regional population-based breast cancer screening programmes in Spain...
  13. pmc Hospital emergency department utilisation rates among the immigrant population in Barcelona, Spain
    Andrea Buron
    Health Services Evaluation and Clinical Epidemiology Department, IMIM Hospital del Mar, Barcelona, Spain
    BMC Health Serv Res 8:51. 2008
    ..However, utilisation rates in our environment have not yet been studied. We aimed to compare emergency department utilisation rates between Spanish-born and foreign-born residents in a public hospital of Barcelona...
  14. pmc Descriptive analysis of childbirth healthcare costs in an area with high levels of immigration in Spain
    Mercè Comas
    Epidemiology and Evaluation Department, IMIM Hospital del Mar, Barcelona, Spain
    BMC Health Serv Res 11:77. 2011
    ..Costs were assessed by taking into account maternal origin and delivery type...
  15. ncbi request reprint The cumulative risk of false-positive results in the Norwegian Breast Cancer Screening Program: updated results
    Marta Roman
    Department of Epidemiology and Evaluation, Hospital del Mar Medical Research Institute, Barcelona, Spain Network for Research into Healthcare in Chronic Diseases, Madrid, Spain
    Cancer 119:3952-8. 2013
    ....
  16. pmc Budget impact analysis of switching to digital mammography in a population-based breast cancer screening program: a discrete event simulation model
    Mercè Comas
    Epidemiology and Evaluation Department, Hospital del Mar, Barcelona IMIM Hospital del Mar Medical Research Institute, Barcelona, Spain Red de investigación en servicios de salud en enfermedades crónicas REDISSEC, Valencia, Spain
    PLoS ONE 9:e97459. 2014
    ..To assess the budgetary impact of switching from screen-film mammography to full-field digital mammography in a population-based breast cancer screening program...
  17. doi request reprint Aggressiveness features and outcomes of true interval cancers: comparison between screen-detected and symptom-detected cancers
    Laia Domingo
    Epidemiology and Evaluation Department, Hospital del Mar IMIM, Barcelona, Spain
    Eur J Cancer Prev 22:21-8. 2013
    ..Clinically detected tumors, especially true interval cancers, more frequently showed biological features related to worse prognosis and were associated with poorer survival even after adjustment for clinical-pathological characteristics...
  18. ncbi request reprint Effect of switching drug formulations from immediate-release to extended-release OROS methylphenidate : a chart review of Spanish adults with attention-deficit hyperactivity disorder
    Josep Antoni Ramos-Quiroga
    Adult ADHD Program, Department of Psychiatry, Hospital Universitari Vall d Hebron, Barcelona, Spain
    CNS Drugs 22:603-11. 2008
    ....
  19. ncbi request reprint Efficacy of psychostimulant drugs for cocaine dependence
    Xavier Castells
    Department of Psychiatry, Hospital Universitari Vall d Hebron and Department of Pharmacology, Therapeutics and Toxicology, , Barcelona, Catalonia, Spain
    Cochrane Database Syst Rev 2:CD007380. 2010
    ..Nevertheless promising results exist for methadone maintained dual heroin-cocaine addicts and for some specific drugs such as dexamphetamine and bupropion...
  20. doi request reprint OROS methylphenidate for the treatment of adults with attention-deficit/hyperactivity disorder
    J Antoni Ramos-Quiroga
    Adult ADHD Program, Department of Psychiatry, Hospital Universitari Vall d Hebron, 08035 Barcelona, Spain
    Expert Rev Neurother 9:1121-31. 2009
    ..Data on dosing, treatment adherence and other clinical parameters relevant for the use of OROS-MPH in adults with ADHD are also reported and discussed...
  21. pmc Determining the lifetime density function using a continuous approach
    Ruben Roman
    Evaluation and Clinical Epidemiology Department, Institut Municipal d Assistència Sanitària IMAS, Passeig Maritim 25 29, 08003, Barcelona, Spain
    J Epidemiol Community Health 61:923-5. 2007
    ..To apply a continuous hazard function approach to calculate the lifetime density function (LDF) at any age, and to compare the life expectancies derived from the LDF with those obtained with standard life table (SLT) methods...
  22. doi request reprint Trends in hormone therapy use before and after publication of the Women's Health Initiative trial: 10 years of follow-up
    Gabriela Barbaglia
    Evaluation and Clinical Epidemiology Department, Hospital Universitari del Mar, Barcelona, Spain
    Menopause 16:1061-4. 2009
    ....
  23. doi request reprint Efficacy of psychostimulant drugs for amphetamine abuse or dependence
    Clara Pérez-Mañá
    Human Pharmacology and Clinical Neurosciences Research Group, Hospital del Mar Research Institute IMIM, Parc de Salut Mar, and Department of Pharmacology, Therapeutics and Toxicology, Universitat Autonoma de Barcelona, Doctor Aiguader 88, Barcelona, Catalonia, Spain, 08003
    Cochrane Database Syst Rev 9:CD009695. 2013
    ..To date, no pharmacological treatment has been approved for this disorder, and psychotherapy remains the mainstay of treatment. In recent years, psychostimulants have been investigated as a possible replacement therapy...
  24. pmc Trends in detection of invasive cancer and ductal carcinoma in situ at biennial screening mammography in Spain: a retrospective cohort study
    Marta Roman
    Department of Epidemiology and Evaluation, IMIM Hospital del Mar Medical Research Institute, Barcelona, Spain Network for Research into Healthcare in Chronic Diseases REDISECC, Madrid, Spain
    PLoS ONE 8:e83121. 2013
    ..The aim of the study was to evaluate the temporal trends in the rates of screen detected invasive cancers and DCIS, and to compare the observed trends with respect to hormone replacement therapy (HRT) use along the same study period...
  25. doi request reprint Feasibility of double-blind clinical trials with oral diacetylmorphine: a randomized controlled phase II study in an inpatient setting
    Joan Colom Farran
    Programme on Substance Abuse, Public Health Agency of Catalonia, Government of Catalonia, Barcelona, Spain
    Eur Addict Res 18:279-87. 2012
    ..i.d. immediate-release oral DAM allowing further phase III clinical trials in the process of introducing oral DAM as a medication for heroin-dependent patients not responding to standard maintenance treatments...
  26. doi request reprint [Results of a study on populational colorectal cancer screening]
    Ricardo Courtier
    Servicio de Cirugia General y del Aparato Digestivo, Hospital Universitario del Mar, Barcelona, Spain
    Cir Esp 85:152-7. 2009
    ..The aim of the study was to analyse the results from a pilot CRC screening programme in a general population sample in Barcelona. A follow-up of false positive cases was made after five years...
  27. ncbi request reprint Amphetamines for Attention Deficit Hyperactivity Disorder (ADHD) in adults
    Xavier Castells
    Unit of Clinical Pharmacology, Department of Medical Sciences, Faculty of Medicine, Universitat de Girona, Girona, Catalonia, Spain
    Cochrane Database Syst Rev 6:CD007813. 2011
    ..Attention Deficit Hyperactivity Disorder (ADHD) is a childhood onset disorder that can persist into adulthood. Amphetamines are used to treat adult ADHD, but uncertainties persist about their efficacy and safety...
  28. pmc Geographical variations in the benefit of applying a prioritization system for cataract surgery in different regions of Spain
    Ruben Roman
    Evaluation and Clinical Epidemiology Department, Institut Municipal d Assistència Sanitària IMAS, Passeig Maritim, 25 29, 08003, Barcelona, Spain
    BMC Health Serv Res 8:32. 2008
    ..Our objective was to assess geographical variations in the impact of applying a prioritization system in patients on the waiting list for cataract surgery in different regions of Spain by using a discrete-event simulation model...
  29. doi request reprint Results of a cervical cancer screening programme from an area of Barcelona (Spain) with a large immigrant population
    Montserrat Casamitjana
    Health Services Evaluation and Clinical Epidemiology Service, Hospital del Mar IMIM, Passeig Marítim 25 029, Barcelona, Spain
    Eur J Public Health 19:499-503. 2009
    ..To assess the participation rate and results of cytological assessment in the context of cervical cancer screening activities in an area of Barcelona (Spain) with a large immigrant population...
  30. pmc Central nervous system gene expression changes in a transgenic mouse model for bovine spongiform encephalopathy
    Raul Tortosa
    Departament de Medicina i Cirurgia Animals, Universitat Autonoma de Barcelona, 08193, Cerdanyola del Valles, Barcelona, Spain
    Vet Res 42:109. 2011
    ..Genes non-previously related to prion diseases should be taken into consideration for further investigations...
  31. ncbi request reprint Gene Expression Profiling in True Interval Breast Cancer Reveals Overactivation of the mTOR Signaling Pathway
    Federico Rojo
    Authors Affiliations Departments of Pathology and Immunology, IIS Fundación Jiménez Díaz, Madrid Cancer Research Program Microarray Core Facility SAM, IMIM Hospital del Mar Medical Research Institute Department of Epidemiology and Evaluation, Hospital del Mar Research Network on Health Services in Chronic Diseases REDISSEC Departments of Pathology, Medical Oncology, and Radiology Department, Hospital del Mar and Universitat Pompeu Fabra, Barcelona, Spain
    Cancer Epidemiol Biomarkers Prev 23:288-99. 2014
    ..We described the differential patterns of gene expression through microarray analysis in true interval and screen-detected cancers...
  32. doi request reprint [Evaluation of the impact of the introduction of a functional knee arthroplasty unit]
    Marta Riu
    Servei d Avaluació i Epidemiologia Clínica, Institut Municipal d Assistència Sanitària IMAS, Barcelona, Spain
    Gac Sanit 23:444-7. 2009
    ..To evaluate the impact of a functional knee arthroplasty unit in Hospital de l'Esperança (Barcelona) on resource consumption, quality indicators and the direct costs of the healthcare process...
  33. doi request reprint Efficacy of indirect dopamine agonists for psychostimulant dependence: a systematic review and meta-analysis of randomized controlled trials
    Clara Pérez-Mañá
    Unit of Human Pharmacology and Neurosciences, Institut de Recerca de l Hospital del Mar, IMIM Parc de Salut Mar, Barcelona, Spain
    J Subst Abuse Treat 40:109-22. 2011
    ..IDAs appear to be efficacious for reducing psychostimulant use but did not improve retention. Efforts should be undertaken to reduce the risk of bias of clinical trials with psychostimulant-dependent individuals...
  34. ncbi request reprint Atomoxetine for attention deficit hyperactivity disorder in the adulthood: a meta-analysis and meta-regression
    Ruth Cunill
    Unitat d hospitalització psiquiàtrica penitenciària, Parc Sanitari Sant Joan de Deu, Barcelona, Spain
    Pharmacoepidemiol Drug Saf 22:961-9. 2013
    ..This study aimed to compare all-cause discontinuation rate between atomoxetine and placebo in adults with ADHD. Secondarily, efficacy and safety were investigated...
  35. ncbi request reprint [Assessing the economic impact of adverse events in Spanish hospitals by using administrative data]
    Natalia Allué
    Servicio de Control de Gestión, Hospital del Mar Parc de Salut Mar, Barcelona, España Servicio de Epidemiología y Evaluación, IMIM Institut Hospital del Mar d Investigacions Mèdiques, Barcelona, España Unidad Docente de Medicina Preventiva y Salud Pública Hospital del Mar Universitat Pompeu Fabra, Agència de Salut Pública de Barcelona, Barcelona, España Programa de doctorado en Salud Pública, Departament de Pediatria, d Obstetrícia i Ginecologia i de Medicina Preventiva, Universitat Autonoma de Barcelona, Barcelona, Espana
    Gac Sanit 28:48-54. 2014
    ..To evaluate the incidence and costs of adverse events registered in an administrative dataset in Spanish hospitals from 2008 to 2010...
  36. pmc Time-trend and variations in the proportion of second-eye cataract surgery
    Lorena Hoffmeister
    Evaluation and Clinical Epidemiology Department, Institut Municipal d Assistència Sanitària, Barcelona, Spain
    BMC Health Serv Res 7:53. 2007
    ..The objective of our study was to estimate the proportion of second-eye cataract surgery, evaluate its time-trend, and explore differences in utilisation by patients' gender, age, and region of residence...
  37. ncbi request reprint Evaluation of hand hygiene adherence in a tertiary hospital
    Ana M Novoa
    Clinical Epidemiology Evaluation Department, Hospital del Mar, IMAS, Barcelona, Spain
    Am J Infect Control 35:676-83. 2007
    ..Evaluation of compliance with hand hygiene was carried out in a Spanish teaching hospital...
  38. doi request reprint Automated brain tumor biopsy prediction using single-labeling cDNA microarrays-based gene expression profiling
    Xavier Castells
    Grup d aplicacions Biomèdiques de la RMN, Departament de Bioquimica i Biologia Molecular, Facultat de Biociencies, Universitat Autonoma de Barcelona, Spain
    Diagn Mol Pathol 18:206-18. 2009
    ..Herewith, we demonstrate that primary brain tumor types can be discriminated using microarray data in an automated and objective way...
  39. ncbi request reprint The effect of obsessive-compulsive symptomatology on executive functions in schizophrenia: a systematic review and meta-analysis
    Ruth Cunill
    Unitat d Hospitalització Psiquiàtrica Penitenciària de Catalunya, Parc Sanitari Sant Joan de Deu, Carretera Martorell Capellades km 23, 08735, Sant Esteve Sesrovires, Barcelona, Catalonia, Spain Electronic address
    Psychiatry Res 210:21-8. 2013
    ..Our findings highlight the complexity of the relationship between OCS/OCD and schizophrenia and warrant further investigation of the cognitive function of schizo-obsessive patients. ..
  40. pmc Impact of immigration on the cost of emergency visits in Barcelona (Spain)
    Francesc Cots
    Health Services Evaluation and Clinical Epidemiology, Department, Institut Municipal d Assistència Sanitària, Barcelona, Spain
    BMC Health Serv Res 7:9. 2007
    ..We aimed to quantify the relative over-utilisation of emergency services in the immigrant population...
  41. ncbi request reprint Trends in lithium prescription in Spain from 1985 to 2003
    Xavier Castells
    Fundacio Institut Catala de Farmacologia, Clinical Pharmacology Service, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
    J Affect Disord 91:273-6. 2006
    ..Lithium prescription increased uninterruptedly from 0.21 to 0.79 DID. The psychiatric reform in Spain and a broader definition of BD during the last decades are possible explanations for this rise...
  42. doi request reprint Interval from diagnosis to treatment onset for six major cancers in Catalonia, Spain
    Gloria Perez
    Agència de Salut Pública de Barcelona, Barcelona, Spain Universitat Pompeu Fabra, Catalonia, Spain
    Cancer Detect Prev 32:267-75. 2008
    ..The objective of the study was to analyse the interval from diagnosis to treatment onset, and related factors, in the six most incident cancers in Catalonia (Spain), a developed European region with universal free access to health care...
  43. doi request reprint [Performance assessment of health services in Catalonia (Spain): evaluation of initial results of the Catalan healthcare service project]
    Anna García-Altés
    Agència de Salut Pública de Barcelona, Barcelona, Spain
    Gac Sanit 23:465-72. 2009
    ....
  44. pmc Cumulative false positive recall rate and association with participant related factors in a population based breast cancer screening programme
    Xavier Castells
    Evaluation and Clinical Epidemiology Department, Institut Municipal d Investigacio Medica IMIM IMAS, Passeig Maritim 25 29, 08003, Barcelona, Spain
    J Epidemiol Community Health 60:316-21. 2006
    ..To investigate the cumulative false positive recall rate throughout the period of participation in a population based breast cancer screening programme and to examine its association with women related factors...