Juan Casado-Vela

Summary

Affiliation: Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM)
Location: Madrid, Spain
URL: www.csic.es

Publications

  1. ncbi Proteomic approach to blossom-end rot in tomato fruits (Lycopersicon esculentum M.): antioxidant enzymes and the pentose phosphate pathway
    Juan Casado-Vela
    Departamento de Agroquimica y Bioquimica, Facultad de Ciencias, Universidad de Alicante, Alicante, Spain
    Proteomics 5:2488-96. 2005
  2. doi Expression of serine proteases in egg-parasitic nematophagous fungi during barley root colonization
    Luis V Lopez-Llorca
    Multidisciplinary Institute for Environmental Studies MIES Ramon Margalef, Department of Marine Sciences and Applied Biology, University of Alicante, Aptdo 99, 03080 Alicante, Spain
    Fungal Genet Biol 47:342-51. 2010
  3. pmc Novel snail1 target proteins in human colon cancer identified by proteomic analysis
    Maria Jesus Larriba
    Instituto de Investigaciones Biomedicas Alberto Sols, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Madrid, Spain
    PLoS ONE 5:e10221. 2010
  4. doi Analysis of root plasma membrane aquaporins from Brassica oleracea: post-translational modifications, de novo sequencing and detection of isoforms by high resolution mass spectrometry
    J Casado-Vela
    Plataforma de Proteómica, CIC bioGUNE, CIBERehd, ProteoRed, Parque Tecnologico de Bizkaia, 48160, Bizkaia, Spain
    J Proteome Res 9:3479-94. 2010
  5. doi A p120-catenin-CK1epsilon complex regulates Wnt signaling
    David Casagolda
    Departament de Bioquimica i Biologia Molecular, CEB, Facultat de Medicina, Universitat Autonoma de Barcelona, E 08193 Bellaterra, Spain
    J Cell Sci 123:2621-31. 2010
  6. doi iTRAQ-based profiling of grape berry exocarp proteins during ripening using a parallel mass spectrometric method
    Maria José Martínez-Esteso
    Grupo de Proteomica y Genomica Funcional de Plantas, Dept Agroquímica y Bioquímica, Facultad de Ciencias, Universidad de Alicante, Alicante, Spain
    Mol Biosyst 7:749-65. 2011
  7. pmc Cohesin organizes chromatin loops at DNA replication factories
    Emmanuelle Guillou
    DNA replication Group, Spanish National Cancer Research Centre CNIO, E 28029 Madrid, Spain
    Genes Dev 24:2812-22. 2010
  8. doi Lights and shadows of proteomic technologies for the study of protein species including isoforms, splicing variants and protein post-translational modifications
    Juan Casado-Vela
    Instituto de Investigaciones Biomedicas Alberto Sols, Spanish National Research Council CSIC, Madrid, Spain
    Proteomics 11:590-603. 2011
  9. doi Changes to the proteome and targeted metabolites of xylem sap in Brassica oleracea in response to salt stress
    N Fernandez-Garcia
    Department of Abiotic Stress and Plant Pathology CEBAS CSIC P O Box 164 Murcia, Spain
    Plant Cell Environ 34:821-36. 2011
  10. doi iTRAQ-based quantitative analysis of protein mixtures with large fold change and dynamic range
    Juan Casado-Vela
    Proteomics Platform, CIC bioGUNE, CIBERehd, ProteoRed, Technology Park of Bizkaia, Derio, Spain
    Proteomics 10:343-7. 2010

Collaborators

Detail Information

Publications21

  1. ncbi Proteomic approach to blossom-end rot in tomato fruits (Lycopersicon esculentum M.): antioxidant enzymes and the pentose phosphate pathway
    Juan Casado-Vela
    Departamento de Agroquimica y Bioquimica, Facultad de Ciencias, Universidad de Alicante, Alicante, Spain
    Proteomics 5:2488-96. 2005
    ..We suggest that these two biochemical pathways, acting as reactive oxygen species scavengers in BER-affected fruits, restrain the spread of the blackening to the whole fruit...
  2. doi Expression of serine proteases in egg-parasitic nematophagous fungi during barley root colonization
    Luis V Lopez-Llorca
    Multidisciplinary Institute for Environmental Studies MIES Ramon Margalef, Department of Marine Sciences and Applied Biology, University of Alicante, Aptdo 99, 03080 Alicante, Spain
    Fungal Genet Biol 47:342-51. 2010
    ..SCP1 shared limited sequence homology with VCP1 and P32. Expression in roots of proteases from nematophagous fungi could be greatly relevant for nematode biocontrol...
  3. pmc Novel snail1 target proteins in human colon cancer identified by proteomic analysis
    Maria Jesus Larriba
    Instituto de Investigaciones Biomedicas Alberto Sols, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Madrid, Spain
    PLoS ONE 5:e10221. 2010
    ..However, only a few studies have used proteomics as a tool for the characterization of proteins mediating EMT...
  4. doi Analysis of root plasma membrane aquaporins from Brassica oleracea: post-translational modifications, de novo sequencing and detection of isoforms by high resolution mass spectrometry
    J Casado-Vela
    Plataforma de Proteómica, CIC bioGUNE, CIBERehd, ProteoRed, Parque Tecnologico de Bizkaia, 48160, Bizkaia, Spain
    J Proteome Res 9:3479-94. 2010
    ..thaliana. To our knowledge, these results represent the deepest characterization of the PIPs isolated from the roots of broccoli, a crop with increasing agronomical interest...
  5. doi A p120-catenin-CK1epsilon complex regulates Wnt signaling
    David Casagolda
    Departament de Bioquimica i Biologia Molecular, CEB, Facultat de Medicina, Universitat Autonoma de Barcelona, E 08193 Bellaterra, Spain
    J Cell Sci 123:2621-31. 2010
    ..Therefore, these results demonstrate a novel and crucial function of p120-catenin in Wnt signaling and unveil additional points of regulation by this factor of β-catenin transcriptional activity different of β-catenin stability...
  6. doi iTRAQ-based profiling of grape berry exocarp proteins during ripening using a parallel mass spectrometric method
    Maria José Martínez-Esteso
    Grupo de Proteomica y Genomica Funcional de Plantas, Dept Agroquímica y Bioquímica, Facultad de Ciencias, Universidad de Alicante, Alicante, Spain
    Mol Biosyst 7:749-65. 2011
    ....
  7. pmc Cohesin organizes chromatin loops at DNA replication factories
    Emmanuelle Guillou
    DNA replication Group, Spanish National Cancer Research Centre CNIO, E 28029 Madrid, Spain
    Genes Dev 24:2812-22. 2010
    ..These results give a new dimension to the role of cohesin in the architectural organization of interphase chromatin, by showing its participation in DNA replication...
  8. doi Lights and shadows of proteomic technologies for the study of protein species including isoforms, splicing variants and protein post-translational modifications
    Juan Casado-Vela
    Instituto de Investigaciones Biomedicas Alberto Sols, Spanish National Research Council CSIC, Madrid, Spain
    Proteomics 11:590-603. 2011
    ..As an example, we discuss the theoretical characterization of the two human choline kinase species, α-1 and α-2, sharing the same catalytic activity but generated by alternative splicing on CHKA gene...
  9. doi Changes to the proteome and targeted metabolites of xylem sap in Brassica oleracea in response to salt stress
    N Fernandez-Garcia
    Department of Abiotic Stress and Plant Pathology CEBAS CSIC P O Box 164 Murcia, Spain
    Plant Cell Environ 34:821-36. 2011
    ..The combination of different methods to analyse the xylem sap composition provides new insights into mechanisms in plant development and signalling under salt stress...
  10. doi iTRAQ-based quantitative analysis of protein mixtures with large fold change and dynamic range
    Juan Casado-Vela
    Proteomics Platform, CIC bioGUNE, CIBERehd, ProteoRed, Technology Park of Bizkaia, Derio, Spain
    Proteomics 10:343-7. 2010
    ..1.1 (Thermo Fisher Scientific). We believe that the presented protein mixtures will be useful to assess the performance of the iTRAQ-based quantitation proteomic strategy in any laboratory...
  11. doi Comprehensive proteomic analysis of human endometrial fluid aspirate
    Juan Casado-Vela
    Proteomics Platform, CIC bioGUNE, CIBERehd, ProteoRed, Technology Park of Bizkaia, Derio, Spain
    J Proteome Res 8:4622-32. 2009
    ..We believe that the thorough catalogue of proteins presented here can serve as a valuable reference for the study of embryo implantation and for future biomarker discovery involved in pathologic alterations of endometrial function...
  12. doi Differential phosphorylation patterns between the Cyclin-A2/CDK2 complex and their monomers
    Juan Casado-Vela
    Protein Technology Unit, Biotechnology Programme, Spanish National Cancer Centre, Madrid, Spain
    Protein Expr Purif 66:15-21. 2009
    ....
  13. ncbi Evaluation of composted sewage sludge as nutritional source for horticultural soils
    J Casado-Vela
    Dpto Agroquímica y Bioquímica, Fac Ciencias, Universidad de Alicante, P O Box 99, E 03080, San Vicente del Raspeig, Alicante, Spain
    Waste Manag 26:946-52. 2006
    ....
  14. ncbi Modified cyclodextrins are chemically defined glucan inducers of defense responses in grapevine cell cultures
    Roque Bru
    Departamento de Agroquimica y Bioquimica, Facultad de Ciencias, Universidad de Alicante, Apartado 99, E 03080 Alicante, Spain
    J Agric Food Chem 54:65-71. 2006
    ..The spent medium of elicited cultures was shown to disturb Botrytis cinerea growth in a plate assay...
  15. ncbi Isolation of a latent polyphenol oxidase from loquat fruit (Eriobotrya japonica Lindl.): kinetic characterization and comparison with the active form
    Susana Sellés-Marchart
    Grupo de Proteomica y Genomica Funcional de Plantas, Departamento de Agroquimica y Bioquimica, Facultad de Ciencias, Universidad de Alicante, Campus de San Vicente del Raspeig, Apdo 99, E 03080 Alicante, Spain
    Arch Biochem Biophys 446:175-85. 2006
    ..The results suggest that the major PPO form for the oxidation of CA, leading to enzymatic browning under physiological conditions, is the latent one...
  16. ncbi Proteomic analysis of tobacco mosaic virus-infected tomato (Lycopersicon esculentum M.) fruits and detection of viral coat protein
    Juan Casado-Vela
    Grupo de Proteomica y Genomica Funcional de Plantas, Departamento de Agroquimica y Bioquimica, Facultad de Ciencias, Universidad de Alicante, Alicante, Spain
    Proteomics 6:S196-206. 2006
    ..PMF and MS/MS data of the 2-D gel-isolated TMV coat protein is proposed as a powerful analysis method for the simultaneous tobamovirus detection, species determination and strain differentiation in virus-infected fruit commodities...
  17. ncbi Effect of composted sewage sludge application to soil on sweet pepper crop (Capsicum annuum var. annuum) grown under two exploitation regimes
    J Casado-Vela
    Dpto Agroquímica y Bioquímica, Fac Ciencias, Universidad de Alicante, P O Box 99, E 03080 San Vicente del Raspeig, Alicante, Spain
    Waste Manag 27:1509-18. 2007
    ....
  18. ncbi Effect of detergents, trypsin and unsaturated fatty acids on latent loquat fruit polyphenol oxidase: basis for the enzyme's activity regulation
    Susana Sellés-Marchart
    Grupo de Proteomica y Genomica Funcional de Plantas, Departamento de Agroquimica y Bioquimica, Facultad de Ciencias, Universidad de Alicante, Campus de San Vicente del Raspeig, Apdo, 99, E 03080 Alicante, Spain
    Arch Biochem Biophys 464:295-305. 2007
    ..Down-regulation of PPO activity by anionic amphiphiles is discussed based on both, the pH profile shift induced upon anionic amphiphile binding and the PPO interaction with negatively charged membranes...
  19. ncbi A combination of neutral loss and targeted product ion scanning with two enzymatic digestions facilitates the comprehensive mapping of phosphorylation sites
    Juan Casado-Vela
    Protein Technology Unit, Biotechnology Programme, Spanish National Cancer Centre, CNIO, Madrid, Spain
    Proteomics 7:2522-9. 2007
    ....
  20. doi Proteomics of multigenic families from species underrepresented in databases: the case of loquat (Eriobotrya japonica Lindl.) polyphenol oxidases
    Susana Sellés-Marchart
    Grupo de Proteomica y Genomica Funcional de Plantas, Departamento de Agroquimica y Bioquimica, Facultad de Ciencias, Universidad de Alicante, Spain
    J Proteome Res 7:4095-106. 2008
    ..Alignment of peptides on their most similar homologous protein revealed divergent amino acid positions that lead to hypothesize the minimal number of genes encoding for the proteins analyzed...
  21. doi Human urine proteomics: building a list of human urine cancer biomarkers
    Juan Casado-Vela
    Translational Oncology Unit, Instituto de Investigaciones Biomedicas Alberto Sols, Spanish National Research Council CSIC, 28029 Madrid, Spain
    Expert Rev Proteomics 8:347-60. 2011
    ..3.80) and primary Swiss-Prot accession numbers, official gene symbols and recommended full names. The main variables that influence urine proteomic experiments are also discussed...