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Species | Enric CarrerasSummaryCountry: Spain Publications
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Publications
CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patientsEnric Carreras
BMT Unit, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
Haematologica 88:306-14. 2003..We report the results of a phase II trial to evaluate feasibility and toxicity of CD34+ selected ASCT (CD34+/ASCT) and treatment results at one year of follow-up...
The incidence of veno-occlusive disease following allogeneic hematopoietic stem cell transplantation has diminished and the outcome improved over the last decadeEnric Carreras
Hematology Department, Hospital Clinic, Institut d Investigacions Biomèdiques Agustí Pi i Sunyer, University of Barcelona, Villaroel 170, Barcelona, Spain
Biol Blood Marrow Transplant 17:1713-20. 2011..In summary, although VOD remains a dreaded early complication of HSCT, technical and therapeutic progress in recent decades have notably reduced its incidence and improved the outcome...
Risk assessment in haematopoietic stem cell transplantation: the liver as a risk factorEnric Carreras
BMT Unit Hospital Clinic Barcelona, Spain
Best Pract Res Clin Haematol 20:231-46. 2007..Finally, as some liver dysfunctions in the stem-cell donor can have a negative impact for the donor during the harvest and/or for the recipient during HSCT, the methodology to evaluate the donors will also be analysed...
Update on fungemia in oncology and hematologyEnric Carreras
Servicio de Hematologia, Hospital Clinic, Barcelona, Spain
Enferm Infecc Microbiol Clin 29:42-7. 2011..Moreover, early identification of patients at risk of fungal infections, as well as identification of patients at risk for fluconazole-resistant strains are topics of increasing interest...
Unrelated donor bone marrow transplantation as treatment for chronic myeloid leukemia: the Spanish experience. The Chronic Myeloid Leukemia Subcommittee of the GETH. Grupo Español de Trasplante HemopoyéticoE Carreras
BMT Section, Hematology Department, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
Haematologica 85:530-8. 2000..To analyze the results of unrelated bone marrow transplantation (UDBMT) as treatment for chronic myeloid leukemia (CML) in Spain...
Veno-occlusive disease of the liver after high-dose cytoreductive therapy with busulfan and melphalan for autologous blood stem cell transplantation in multiple myeloma patientsEnric Carreras
Haematology Department of Hospital Clínic, Barcelona, Spain
Biol Blood Marrow Transplant 13:1448-54. 2007..026). This high incidence of severe VOD probably had a multifactorial origin (busulfan followed by melphalan and previous use of BCNU). This observation should be kept in mind when designing future trials for the treatment of MM...
Engraftment syndrome after auto-SCT: analysis of diagnostic criteria and risk factors in a large series from a single centerE Carreras
Department of Hematology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
Bone Marrow Transplant 45:1417-22. 2010..In doubtful cases, the diagnosis could be confirmed by evaluating CRP. Auto-SCT in patients not receiving previous chemotherapy could explain the increasing incidence of ES in the past years...
Donor age and degree of HLA matching have a major impact on the outcome of unrelated donor haematopoietic cell transplantation for chronic myeloid leukaemiaE Carreras
Spanish Bone Marrow Donor Registry REDMO, IDIBAPS, Barcelona, Spain
Bone Marrow Transplant 37:33-40. 2006..Our analysis shows that in patients with a young and fully allele-matched donor, UD-HCT should be considered in the initial therapeutic algorithm due to its excellent outcome (92% survival at 2 years)...
Clinical factors influencing T-cell receptor excision circle (TRECs) counts following allogeneic stem cell transplantation in adultsMonica Jimenez
Department of Hematology, Institute of Hematology and Oncology, Institut d Investigacions Biomediques August Pi i Sunyer, IDIBAPS, Hospital Clinic, University of Barcelona, Spain
Transpl Immunol 16:52-9. 2006..032). Our data support the concept that adult thymus contributes with a slow but continuous production of thymic T cells to immune reconstitution after SCT. Chronic GVHD is the main factor associated to a delay in TRECs counts recovery...
Severe infections after unrelated donor allogeneic hematopoietic stem cell transplantation in adults: comparison of cord blood transplantation with peripheral blood and bone marrow transplantationRocio Parody
Division of Clinical Hematology, Hospital Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
Biol Blood Marrow Transplant 12:734-48. 2006....
Anemia associated with impaired erythropoietin secretion after allogeneic stem cell transplantation: incidence, risk factors, and response to treatmentAnna Gaya
Department of Hematology, Institute of Hematoncology, Hospital Clinic of Barcelona, Barcelona, Spain
Biol Blood Marrow Transplant 14:880-7. 2008..This complication easily reverts with ESP, which seems to contribute to reduce iron overload...
Reduced-intensity conditioning regimen preserves thymic function in the early period after hematopoietic stem cell transplantationMonica Jimenez
Department of Hematology, Institute of Hematology and Oncology, Institut d Investigacions Biomediques August Pi i Sunyer, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
Exp Hematol 33:1240-8. 2005..To compare T-cell reconstitution in two groups of patients submitted to allogeneic stem cell transplantation (SCT): those receiving reduced-intensity conditioning (RIC, n = 24) and those receiving myeloablative conditioning (MA, n = 27)...
Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneic stem cell transplantationMiquel Granell
Departments of Hematology, , Barcelona, Spain
Exp Hematol 34:1435-41. 2006..8, p = 0.02) retained independent prognostic value. CONCLUSION: These results show for the first time that polymorphisms responsible for not only MBL but also MASP-2 deficiency are independent predictive factors for IFI after allo-SCT...
Case-control comparison of at-home to total hospital care for autologous stem-cell transplantation for hematologic malignanciesFrancesc Fernandez-Aviles
Department of Hematology, Institute of Hematology and Oncology, IDIBAPS, Postgraduate School of Hematology Farreras Valenti, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain
J Clin Oncol 24:4855-61. 2006..We developed an at-home ASCT program in which prophylactic ceftriaxone and treatment of febrile neutropenia with piperacillin and tazobactam was introduced to minimize the readmission rate...
Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantationMiquel Granell
Hematology Department, Hospital Clinic of Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
Blood 112:4337-42. 2008..If validated in larger studies, including unrelated allo-SCT, NLRPs genotype would become an important factor in donor selection...
Autologous stem cell transplantation for patients with active Hodgkin's lymphoma: long-term outcome of 61 patients from a single institutionCarmen Martinez
Department of Hematology, Institute of Hematology and Oncology, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
Leuk Lymphoma 48:1968-75. 2007..Although long-term outcome of patients with active HL at the time of ASCT is poor due to a high TRM and a low CR after transplantation, a subgroup of patients with no adverse prognostic factors at ASCT gain benefit from this treatment...
Low-dose total-body irradiation and fludarabine followed by hematopoietic cell transplantation from HLA-identical sibling donors do not induce complete T-cell donor engraftment in most patients with progressive hematologic diseasesFrancesc Fernandez-Aviles
Institute of Hematology and Oncology, IDIBAPS, Postgraduate School of Hematology Farreras Valenti, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain
Exp Hematol 31:934-40. 2003....
Effect of NOD2/CARD15 variants in T-cell depleted allogeneic stem cell transplantationMiquel Granell
Department of Hematology, Hospital Clinic of Barcelona, Institut d Investigacions Biomediques August Pi i Sunyer, Faculty of Medicine, University of Barcelona, Spain
Haematologica 91:1372-6. 2006..We hypothesized that the clinical effect of SNP in NOD2/CARD15 might be different in patients submitted to T-cell-depleted allogeneic SCT, in which donor T cells, the main effectors of GVHD, are eliminated...
CD34+-enriched-CD19+-depleted autologous peripheral blood stem cell transplantation for chronic lymphoproliferative disorders: high purging efficiency but increased risk of severe infectionsAlbert Altes
Clinical Hematology Division, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
Exp Hematol 30:824-30. 2002..The main objective of this work was to decrease the incidence of relapse after autologous stem cell transplantation with a "double purging" procedure...
Prospective evaluation of procalcitonin in adults with febrile neutropenia after haematopoietic stem cell transplantationMar Ortega
Infectious Diseases Unit, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona Spain
Br J Haematol 126:372-6. 2004..However, when fever persisted for more than 5 d, PCT values > or = 3 ng/ml had a high sensitivity and specificity for the diagnosis of invasive aspergillosis...
Endothelial dysfunction after hematopoietic stem cell transplantation: role of the conditioning regimen and the type of transplantationMarta Palomo
Hemotherapy Hemostasis Department, Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain
Biol Blood Marrow Transplant 16:985-93. 2010..However, the comparative analysis between patients with and without complications suggests that none of these markers has diagnostic or prognostic value...
Role of depression as a predictor of mortality among cancer patients after stem-cell transplantationJesús M Prieto
Department of Psychiatry, Clinical Institute of Psychiatry and Psychology, University of Barcelona, Spain
J Clin Oncol 23:6063-71. 2005..To determine the association between depression and survival among cancer patients at 1, 3, and 5 years after stem-cell transplantation (SCT)...
Bacterial and fungal bloodstream isolates from 796 hematopoietic stem cell transplant recipients between 1991 and 2000Mar Ortega
Infectious Diseases Unit, Hospital Clinic, C Villarroel 170, 08036 Barcelona, Spain
Ann Hematol 84:40-6. 2005..CoNS were the leading pathogen during the 10 years of study and during the three phases of immune recovery after HSCT. Crude mortality of HSCT patients with BSI was low except for infections caused by Candida spp...
Detection of Aspergillus galactomannan by enzyme immunoabsorbent assay in recipients of allogeneic hematopoietic stem cell transplantation: a prospective studyMontserrat Rovira
Bone Marrow Transplant Unit, Department of Hematology, Postgraduate School of Hematology Farreras Valenti, Hospital Clinic, University of Barcelona, Spain
Transplantation 77:1260-4. 2004..This study validates the usefulness of this diagnostic tool in the allo-HSCT setting...
Psychometric study of quality of life instruments used during hospitalization for stem cell transplantationJesús M Prieto
Department of Psychiatry, Clinical Institute of Psychiatry and Psychology, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
J Psychosom Res 57:201-11. 2004....
Cost-effectiveness of posaconazole versus fluconazole or itraconazole in the prevention of invasive fungal infections among high-risk neutropenic patients in SpainSantiago Grau
Hospital del Mar, Barcelona, Spain
BMC Infect Dis 12:83. 2012..The perspective was that of the Spanish National Health Service (NHS)...
The release of soluble factors contributing to endothelial activation and damage after hematopoietic stem cell transplantation is not limited to the allogeneic setting and involves several pathogenic mechanismsMarta Palomo
Hemotherapy Hemostasis Department, Centre de Diagnostic Biomedic, University of Barcelona, Barcelona, Spain
Biol Blood Marrow Transplant 15:537-46. 2009..Further studies are needed to explore the association between this endothelial damage and the vascular complications associated with HSCT...
High dose chemotherapy and autologous stem cell transplantation in patients with peripheral T-cell lymphoma not achieving complete response after induction chemotherapy. The GEL-TAMO experienceJose Rodriguez
Servicio de Hematologia, Hospital Universitario Son Dureta, Av Andrea Doria 55, Palma de Mallorca 07014, Spain
Haematologica 88:1372-7. 2003..The aim of this study was to analyze the efficacy of this therapy in the corresponding patients with peripheral T-cell lymphoma (PTCL)...
Pretransplantation liver function impacts on the outcome of allogeneic hematopoietic stem cell transplantation: a study of 455 patientsPere Barba
Hematology Departments of Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona and Universitat Autònoma de Barcelona, Mas Casanovas 90, Barcelona, Spain
Biol Blood Marrow Transplant 17:1653-61. 2011..In conclusion, hepatic dysfunction before allo-SCT is frequent and has an impact on transplantation outcomes. The best indicator of liver dysfunction still has to be determined...
Autologous haematopoietic-stem-cell transplantation for multiple sclerosisYolanda Blanco
Service of Neurology, , , University of Barcelona, Spain
Lancet Neurol 4:54-63. 2005..The course of MS seems to be stabilised after autologous HSCT, especially in ambulatory patients with evidence of active disease. Autologous HSCT deserves further study in randomised controlled trials...
Non-myeloablative hematopoietic stem cell transplantation in the treatment of severe idiopathic CD4+ lymphocytopeniaCarlos Cervera
Services of Infectious Diseases, Hospital Clinic of Barcelona, University of Barcelona, IDIBAPS, Barcelona, Spain
Eur J Haematol 87:87-91. 2011..Non-myeloablative allogeneic hematopoietic stem cell transplantation should be considered a treatment option for patients with severe forms of idiopathic CD4+ lymphocytopenia...
Defibrotide prevents the activation of macrovascular and microvascular endothelia caused by soluble factors released to blood by autologous hematopoietic stem cell transplantationMarta Palomo
Hemotherapy Hemostasis Department, Centre de Diagnostic Biomedic, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain
Biol Blood Marrow Transplant 17:497-506. 2011....
Imatinib as a potential treatment for sclerodermatous chronic graft-vs-host diseaseJuan A Moreno-Romero
Department of Dermatology, , University of Barcelona, Barcelona, Spain
Arch Dermatol 144:1106-9. 2008
Hematopoietic stem cell transplantation for multiple myeloma beyond 2010Joan Blade
Department of Hematology and Bone Marrow Transplant Unit, Institut of Hematology and Oncology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
Blood 115:3655-63. 2010..The development of novel reduced-intensity preparative regimens and peri- and posttransplantation strategies aimed at minimizing graft-versus-host disease, and enhancing the graft-versus-myeloma effect are key issues...
Prevalence of neurological damage in monochorionic twins with selective intrauterine growth restriction and intermittent absent or reversed end-diastolic umbilical artery flowE Gratacos
Fetal Medicine Unit and Department of Obstetrics and Gynecology, University Hospital Vall d Hebron, Barcelona, Spain
Ultrasound Obstet Gynecol 24:159-63. 2004....
Allogenic stem cell transplantation as salvage therapy for patients relapsing after autologous transplantation: experience from a single institutionC Martinez
Transplantation Unit, Department of Hematology, Postgraduate School of Hematology Farreras Valenti, Institute of Hematology and Oncology, IDIBAPS Hospital Clinic, University of Barcelona, Villarroel 170, 08036, Barcelona, Spain
Leuk Res 25:379-84. 2001..However, the procedure is associated with a high transplant-related mortality. Better results might be obtained by carefully selecting patients and by reducing the intensity of the preparative regimen...
Favourable effect of the combination of acute and chronic graft-versus-host disease on the outcome of allogeneic peripheral blood stem cell transplantation for advanced haematological malignanciesS Brunet
Division of Clinical Haematology, Hospital de la Sant Creu i Sant Pau, Barcelona, Spain
Br J Haematol 114:544-50. 2001..03). Our results indicate a reduced incidence of relapse for patients with AHM receiving an unmodified allo-PBT and developing acute and chronic GVHD, which results in an improved DFS...
[Febrile neutropenia: past, present and future]Enric Carreras
, , IDIBAPS, Barcelona,
Enferm Infecc Microbiol Clin 23:2-6. 2005....
Anti-D alloimmunization after D-mismatched allogeneic hematopoietic stem cell transplantation in patients with hematologic diseasesJoan Cid
Department of Hemotherapy, August Pi i Sunyer Biomedical Research Institute (IDIBAPS, Hospital Clinic Provincial, University of Barcelona, Barcelona, Spain
Transfusion 46:169-73. 2006..CONCLUSION: Anti-D alloimmunization after performing a D-mismatched AHSCT is infrequent in patients with hematologic diseases although patients receive D-mismatched PLT transfusions without RhIG administration...
Collection of Philadelphia-negative stem cells using recombinant human granulocyte colony-stimulating factor in chronic myeloid leukemia patients treated with alpha-interferonJuan Carlos Hernández-Boluda
BMT Unit, Institute of Hematology and Oncology, Department of Hematology, Hospital del Mar, Villaroel 170, 08036 Barcelona, Spain
Haematologica 87:17-22. 2002..The results of using recombinant human granulocyte colony-stimulating factor (rHuG-CSF) for harvesting hematopoietic progenitors in CML patients treated with interferon-a (IFN) are reported...
Changes of matrix metalloproteinase-9 and its tissue inhibitor (TIMP-1) after autologous hematopoietic stem cell transplantation in multiple sclerosisYolanda Blanco
Services of Neurology, , , University of Barcelona, Villarroel 170, Barcelona 08036, Spain
J Neuroimmunol 153:190-4. 2004..MMP-9 mRNA levels correlated with the CD4+ T cell count (p<0.0001). The significant and persistent change in MMP-9 activity after AHSCT may be caused in part by the effect of AHSCT in the CD4+ T cell count...
[Clinical outcome 6 years after autologous hematopoietic stem cell transplantation in multiple sclerosis]A Saiz
Servicio de Neurologia, Hematología Hospital Clínic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Barcelona
Neurologia 23:405-7. 2008..We describe the clinical outcome of 14 patients included in a protocol of AHSCT after a median follow-up period of 6 years...
[Guidelines for the treatment on infections caused by methicillin-resistant Staphylococcus aureus]J Mensa
Sociedad Española de Quimioterapia SEQ, Servicio de Enfermedades Infecciosas, Hospital Clinic, Barcelona, Espana
Rev Esp Quimioter 21:234-58. 2008..Under this situation guidelines for the treatment of common infections caused by MRSA appear to be necessary to improve the efficacy and reduce the mortality...
The use of a variable cut-off value of cervical length in women admitted for preterm labor before and after 32 weeksM Palacio
Prematurity Unit, Department of Maternal Fetal Medicine, Institut Clinic de Ginecologia, Obstetricia i Neonatologia, Hospital Clinic de Barcelona, Barcelona, Spain
Ultrasound Obstet Gynecol 29:421-6. 2007..To determine whether the optimal cut-off value to predict low risk of preterm delivery in women admitted for preterm labor should be adjusted for gestational age...
Twin chorionicity and the risk of adverse perinatal outcomeR Acosta-Rojas
Unitat de Medicina Fetal, Servei d Obstetricia, Hospital Materno Infantil Vall d Hebron, Barcelona, Spain
Int J Gynaecol Obstet 96:98-102. 2007..To evaluate the impact of chorionicity on the perinatal outcomes of twin pregnancies complicated by twin-twin transfusion syndrome (TTS) or selective intrauterine growth restriction (sIUGR)...
A classification system for selective intrauterine growth restriction in monochorionic pregnancies according to umbilical artery Doppler flow in the smaller twinE Gratacos
Fetal Medicine Unit and Department of Obstetrics, Hospital Clinic IDIBAPS, University of Barcelona, Barcelona, Spain
Ultrasound Obstet Gynecol 30:28-34. 2007....
CsA-based post-graft immunosuppression: the main factor for improving outcome of allografted patients with acquired aplastic anemia. A retrospective survey by the Spanish Group of Hematopoietic TransplantationR Arranz
Hematology Department, Hospital Universitario de la Princesa, Madrid, Spain
Bone Marrow Transplant 29:205-11. 2002..Regardless of CsA use, further improvement in survival was apparent with time, probably due to better skills in patient care...
Dramatic improvement of POEMS syndrome following autologous haematopoietic cell transplantationM Rovira
Department of Haematology, BMT Unit, Postgraduate School of Haematology Farreras Valenti, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Barcelona, Spain
Br J Haematol 115:373-5. 2001..We believe that this is the first reported case of POEMS syndrome treated with AHCT, a procedure that could be considered in similarly affected patients...
Allogeneic transplantation of CD34(+) selected cells from peripheral blood from human leukocyte antigen-identical siblings: detrimental effect of a high number of donor CD34(+) cells?A Urbano-Ispizua
Institute of Hematology and Oncology, Bone Marrow Transplant Unit, Postgraduate School of Hematology Farreras Valenti, University of Barcelona, Spain
Blood 98:2352-7. 2001....
Clinical and MRI outcome after autologous hematopoietic stem cell transplantation in MSA Saiz
Services of Neurology, , , University of Barcelona, Spain
Neurology 62:282-4. 2004..The mean change in T2 lesion volume from baseline to the third year was -20.2% and that of the corpus callosum area was -12.7%; 50% of this reduction was seen during the first year...
Psychiatric morbidity and impact on hospital length of stay among hematologic cancer patients receiving stem-cell transplantationJesús M Prieto
Department of Psychiatry, Clinical Institute of Psychiatry and Psychology and Stem Cell Transplantation Unit, University of Barcelona, Barcelona, Spain
J Clin Oncol 20:1907-17. 2002..To determine the prevalence of psychiatric disorders during hospitalization for hematopoietic stem-cell transplantation (SCT) and to estimate their impact on hospital length of stay (LOS)...
[Autologous haematopoietic stem cell transplantation in POEMS syndrome: results in 4 cases]Pau Abrisqueta
Instituto de Hematología y Oncología, Servicio de Hematologia, Unidad de TPH, Hospital Clinic, IDIBAPS, Universidad de Barcelona, Barcelona, Espana
Med Clin (Barc) 129:578-81. 2007..The monoclonal component and bone lesions decreased or disappeared. In conclusion, autologous haematopoietic stem cell transplantation is an effective therapy in patients with POEMS syndrome...
Hla-DPB1 mismatch in HLA-A-B-DRB1 identical sibling donor stem cell transplantation and acute graft-versus-host diseaseDavid Gallardo
Alloreactivity Unit of the Institut Català d Oncologia, Barcelona, Spain
Transplantation 77:1107-10. 2004..A higher incidence of acute graft-versus-host disease (aGVHD) has been described after unrelated donor bone marrow transplant when both HLA-DPB1 alleles were mismatched...
Autologous stem-cell transplantation for Hodgkin's disease: results and prognostic factors in 494 patients from the Grupo Español de Linfomas/Transplante Autólogo de Médula Osea Spanish Cooperative GroupA Sureda
Clinical Hematolgy Division, Hospital de la Santa Creu i Sant Pau, St Antoni Maria Claret, Barcelona, Spain
J Clin Oncol 19:1395-404. 2001..To analyze clinical outcome and significant prognostic factors for overall (OS) and time to treatment failure (TTF) in a group of 494 patients with Hodgkin's disease (HD) undergoing autologous stem-cell transplantation (ASCT)...
Incidence and characteristics of umbilical artery intermittent absent and/or reversed end-diastolic flow in complicated and uncomplicated monochorionic twin pregnanciesE Gratacos
Fetal Medicine Unit and Department of Obstetrics and Gynecology, University Hospital Vall d Hebron, Barcelona, Spain
Ultrasound Obstet Gynecol 23:456-60. 2004..To evaluate the incidence and clinical relevance of intermittent absent and/or reversed diastolic flow on umbilical artery Doppler in different groups of monochorionic twin pregnancies...
High-dose therapy/autologous stem cell transplantation in patients with chemosensitive multiple myeloma: predictors of complete remissionE Nadal
Hematology Department, BMT Section, Institute of Hemato-Oncology, , IDIBAPS, Barcelona, Spain
Bone Marrow Transplant 33:61-4. 2004..Finally, the pretransplant features significantly associated to CR were a low M-protein size (serum </=10 g/l and urine <0.5 g/24 h) (P=0.0003) and a proportion of bone marrow plasma cells of </=5% (P=0.02)...
Disparity for the minor histocompatibility antigen HA-1 is associated with an increased risk of acute graft-versus-host disease (GvHD) but it does not affect chronic GvHD incidence, disease-free survival or overall survival after allogeneic human leucocytD Gallardo
Alloreactivity Unit of the Institut Català d Oncologia, Hospital Duran i Reynals, Avda Gran Via s n, Km 2 7, 08907 L Hospitalet, Barcelona, Spain
Br J Haematol 114:931-6. 2001..These results confirmed the association between HA-1 mismatch and risk of mild acute GvHD, but HA-1 mismatch was not associated with an increased incidence of chronic GvHD and did not affect relapse or overall survival...
MTX or mycophenolate mofetil with CsA as GVHD prophylaxis after reduced-intensity conditioning PBSCT from HLA-identical siblingsJ L Piñana
Division of Clinical Hematology, Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
Bone Marrow Transplant 45:1449-56. 2010..3 and 52 vs 51%, P=0.7, respectively). Our results support further prospective studies comparing the use of the CsA/MMF combination with CsA/MTX as GVHD prophylaxis in HLA-identical sibling donor allo-RIC recipients...
Incidence and outcome of hepatic veno-occlusive disease after blood or marrow transplantation: a prospective cohort study of the European Group for Blood and Marrow Transplantation. European Group for Blood and Marrow Transplantation Chronic Leukemia WorkE Carreras
Hospital Clinic, IDIBAPS, Barcelona, Spain University of Freiburg, Freiburg, Germany Universita degli Studi La Sapienza, Rome, Italy
Blood 92:3599-604. 1998....
Stem cell transplantation for chronic lymphocytic leukemia: different outcome after autologous and allogeneic transplantation and correlation with minimal residual disease statusJ Esteve
Institute of Hematology and Oncology, Department of Hematology, University of Barcelona, Spain
Leukemia 15:445-51. 2001..These results show that in CLL the probability of achieving sustained MRD(-) CR is higher with allogeneic than with autologous transplants, and confirm the value of MRD assessment in the follow-up of patients transplanted for CLL...
Patient-rated emotional and physical functioning among hematologic cancer patients during hospitalization for stem-cell transplantationJ M Prieto
Department of Psychiatry, Clinical Institute of Psychiatry and Psychology, IDIBAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
Bone Marrow Transplant 35:307-14. 2005..These findings have implications for treatment decision making, coping with the transplantation process, and improving prevention and treatment strategies...
[The autologous transplantation of hematopoietic precursors on an outpatient basis: an analysis of its feasibility at the Hospital Clínic de Barcelona]S Rives
Sección de Trasplante Hemopoyético, Hospital Clinic, Barcelona
Med Clin (Barc) 113:201-4. 1999..Preliminary results show a significant financial saving without modifying the therapeutic results. The aim of this study has been to evaluate the feasibility of this procedure in our the Hospital Clínic of Barcelona, Spain...
Incidence and characterization of secondary myelodysplastic syndromes following autologous transplantationM f Del Cañizo
Servicio de Hematologia, Hospital Universitario de Salamanca, P masculine de San Vicente, 58 182, 37007 Salamanca, Spain
Haematologica 85:403-9. 2000..The aim of the present study was to analyze Spanish experience regarding the incidence and characteristics of sMDS and sAML following autologous transplantation...
Measurement of C-reactive protein in adults with febrile neutropenia after hematopoietic cell transplantationM Ortega
Institut Clinic d Infeccions i Immunologia, Hospital Clinic, IDIBAPS, University of Barcelona, Spain
Bone Marrow Transplant 33:741-4. 2004..We conclude that persistent elevation of the CRP is an independent factor predicting a fatal outcome in patients who remain febrile on the fifth day of antibiotherapy during neutropenic febrile episodes post-HCT...
Salvage chemotherapy with alternating MINE-ESHAP regimen in relapsed or refractory Hodgkin's lymphoma followed by autologous stem-cell transplantationC Fernández de Larrea
Department of Hematology, University of Barcelona, Barcelona, Spain
Ann Oncol 21:1211-6. 2010..However, the optimal salvage regimen has not yet been established...
[Meta-analysis on safety and efficacy of liposomal amphotericin B in the empirical treatment of febrile neutropenia]Xavier Badia
Grupo Health Outcomes Research Europe, Barcelona, Spain
Med Clin (Barc) 122:610-6. 2004..We compared the safety and efficacy of liposomal amphotericin B with other formulations of amphotericin B and voriconazol as an empirical treatment of febrile neutropenia...
Immune reconstitution following allogeneic peripheral blood progenitor cell transplantationC Martinez
Hematology Department, IDIBAPS, Hospital Clinic, University of Barcelona Spain
Leuk Lymphoma 37:535-42. 2000..A review of some quantitative and functional aspects of immune recovery after allo-PBPCT is presented in this article...
MRI and CSF oligoclonal bands after autologous hematopoietic stem cell transplantation in MSA Saiz
Services of Neurology, , , University of Barcelona, Spain
Neurology 56:1084-9. 2001....
Hematopoietic stem cell transplantation in chronic lymphocytic leukemia: a report of 12 patients from a single institutionJ Esteve
Department of Hematology, University of Barcelona, Spain
Ann Oncol 9:167-72. 1998..Stem-cell transplantation is a reasonable therapeutic approach for younger patients with high-risk CLL...
Description of a novel HLA-DRB1 allele found in a candidate for bone marrow transplantationV Mas
Servei d Immunologia, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Hospital Clinic, Barcelona, Spain
Tissue Antigens 64:304-7. 2004..We discuss the criteria of selecting a non-related bone marrow donor with a minor mismatch on the DRB1* allele or the related father having a minor mismatch at B locus and a C-locus mismatch...
Evolution of brain-derived neurotrophic factor levels after autologous hematopietic stem cell transplantation in multiple sclerosisY Blanco
Services of Neurology, , Villarroel 170, Barcelona 08036, Spain
Neurosci Lett 380:122-6. 2005..Our study suggests that AHSCT can reduce BDNF levels to values associated with lower activity. This decrease does not seem to correlate with the brain atrophy measures observed in the MRI...
Prospective evaluation of procalcitonin in adults with non-neutropenic fever after allogeneic hematopoietic stem cell transplantationM Ortega
Infectious Diseases Unit, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain
Bone Marrow Transplant 37:499-502. 2006..5 (+/- 3.4) in possible IFI and 1.5 (+/- 0.9) in infections other than IFI. Therefore, we could conclude that during the non-neutropenic phases of allogeneic HSCT, a high PCT value is associated significantly with IA...
Autologous stem cell transplantation for primary refractory Hodgkin's disease: results and clinical variables affecting outcomeM Constans
Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Ann Oncol 14:745-51. 2003..Despite this, other therapeutic strategies should be investigated in this group of patients to improve the outcome...
Successful treatment of severe hemorrhagic cystitis after hemopoietic cell transplantation by selective embolization of the vesical arteriesE Gine
BMT Unit, Hematology Department, Institute of Hematology and Oncology, Postgraduate School of Hematology, Spain
Bone Marrow Transplant 31:923-5. 2003..We report two HCT patients with severe HC successfully treated with selective embolization of the vesical arteries...
[Prevention of fungal infections of endogenic origin]M Rovira
, , , , IDIBAPS, Universitat de Barcelona, Barcelona, Spain
Rev Esp Quimioter 17:101-4. 2004
Effectiveness of virosomal subunit influenza vaccine in preventing influenza-related illnesses and its social and economic consequences in children aged 3-14 years: a prospective cohort studyL Salleras
Preventive Medicine Unit, Department of Public Health, School of Medicine, University of Barcelona, Casanova 143, Barcelona, Spain
Vaccine 24:6638-42. 2006..Vaccination of children aged 3-14 years in pediatric practices with one dose of virosomal subunit inactivated influenza vaccine has the potential to considerably reduce the health and social burdens caused by influenza-related illnesses...
Allogeneic and syngeneic hematopoietic cell transplantation in patients with amyloid light-chain amyloidosis: a report from the European Group for Blood and Marrow TransplantationStefan O Schonland
University of Heidelberg, Dept of Hematology Oncology and Rheumatology, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
Blood 107:2578-84. 2006..These data suggest that allo-SCT might be a promising and potentially curative treatment modality for selected patients with AL amyloidosis...
Influence of the intensity of the conditioning regimen on the characteristics of acute and chronic graft-versus-host disease after allogeneic transplantationJose A Perez-Simon
Servicio de Hematlogía, Hospital Clinico Universitario, Salamanca, Spain
Br J Haematol 130:394-403. 2005....
Feasibility and results of autologous stem cell transplantation in de novo acute myeloid leukemia in patients over 60 years old. Results of the CETLAM AML-99 protocolAlbert Oriol
CETLAM Group, Catalonia, Spain
Haematologica 89:791-800. 2004..We assessed the proportion of patients over 60 years with de novo AML who qualified for intensive therapy and determined the feasibility and results of autologous stem cell transplantation (ASCT) in first complete remission (CR)...
Late response to donor lymphocyte infusions in patients with chronic myeloid leukemia relapsing after allogeneic stem cell transplantationMarta Gomez
Haematologica 87:1003-5. 2002..The median time (range) in months to achieve a hematologic, cytogenetic and molecular remission was 2 (1-2), 5 (1-42) and 5 the median response duration is 16 months (range 1-36), and no patient shows evidence of relapse...
Clinical factors associated with fatigue in haematologic cancer patients receiving stem-cell transplantationJesús M Prieto
Department of Psychiatry, Institut d Assistencia Sanitaria, Girona, Spain
Eur J Cancer 42:1749-55. 2006..Our findings may help to shed light on the mechanisms underlying fatigue and may also guide future interventions...
Allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia in Europe 2006: transplant activity, long-term data and current results. An analysis by the Chronic Leukemia Working Party of the European Group for Blood and Marrow TransplanAlois Gratwohl
Hematology, University Hospital Basel, Switzerland
Haematologica 91:513-21. 2006..HSCT remains an important treatment option for patients with CML. The data describe the current status of this option and the outcome a patient can expect today. They provide an objective basis for decision making...
Stem cell transplantation: risk factors for psychiatric morbidityJesús M Prieto
Department of Psychiatry, Institut d Assistencia Sanitaria, Girona, Spain
Eur J Cancer 42:514-20. 2006..Our study findings may help to improve identification of the patients most at risk for psychiatric disturbances during hospitalization for stem cell transplantation...
Nonmalignant late effects after allogeneic stem cell transplantationGerard Socie
Hematology Stem Cell Transplantation, Hopital Saint Louis, Paris, France
Blood 101:3373-85. 2003
Retrospective comparison of bone marrow and granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells for allogeneic stem cell transplantation using HLA identical sibling donors in myelodysplastic syndromesPhilippe Guardiola
Service de Greffe de Moelle, Hopital Saint Louis, Paris, France
Blood 99:4370-8. 2002....
Bone marrow transplantation from HLA-identical siblings as treatment for myelodysplasiaJorge Sierra
International Bone Marrow Transplant Registry (IBMTR, Health Policy Institute, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Blood 100:1997-2004. 2002..Best candidates are younger patients with a low percentage of blasts and preserved platelet counts...
