Research Topics
Species | Ana Bustamante-AragonesSummaryCountry: Spain Publications
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Detail Information
Publications
Foetal sex determination in maternal blood from the seventh week of gestation and its role in diagnosing haemophilia in the foetuses of female carriersA Bustamante-Aragones
Department of Genetics, Fundacion Jimenez Diaz Capio, CIBERER, Madrid, Spain
Haemophilia 14:593-8. 2008..Reliable foetal gender determination from maternal blood of pregnant women carriers of haemophilia in the first trimester of gestation can avoid more conventional, invasive methods of prenatal diagnosis...
Early noninvasive prenatal detection of a fetal CRB1 mutation causing Leber congenital amaurosisAna Bustamante-Aragones
Department of Genetics, Fundacion Jimenez Diaz Capio, CIBERER, Madrid, Spain
Mol Vis 14:1388-94. 2008..The aim of the present work was to study a fetal mutation associated to LCA in maternal plasma by a new methodology in the noninvasive prenatal diagnosis field: the denaturing High Performance Liquid Chromatography (dHPLC)...
New strategy for the prenatal detection/exclusion of paternal cystic fibrosis mutations in maternal plasmaAna Bustamante-Aragones
Department of Genetics Fundacion Jimenez Diaz Capio, CIBERER 28040 Madrid, Spain
J Cyst Fibros 7:505-10. 2008..Here, we present a new strategy for the detection of fetal mutations causing CF in maternal plasma...
Prenatal diagnosis in maternal plasma of a fetal mutation causing propionic acidemiaAna Bustamante-Aragones
Department of Genetics, Fundacion Jimenez Diaz Capio, CIBERER, Madrid, Spain
Mol Genet Metab 95:101-3. 2008..In this work, we have correctly diagnosed in maternal plasma the status of a fetus at risk of PA for the paternal mutation...
Prenatal diagnosis of Huntington disease in maternal plasma: direct and indirect studyA Bustamante-Aragones
Department of Genetics, Fundacion Jimenez Diaz, Madrid, Spain
Eur J Neurol 15:1338-44. 2008..The presence of cell-free fetal DNA in maternal plasma could allow performing a non-invasive prenatal diagnosis of Huntington disease (HD). The great advantage of this diagnosis is the absence of risk of fetal loss that it entails...
Noninvasive prenatal diagnosis using ccffDNA in maternal blood: state of the artAna Bustamante-Aragones
Department of Genetics, Fundacion Jimenez Diaz Capio, Avda Reyes Catolicos, 2 28040, Madrid, Spain
Expert Rev Mol Diagn 10:197-205. 2010..However, new discoveries and technology are making NIPD a real option for patients and providing for an array of clinical applications, such as molecular studies in high-risk families, general screening and pregnancy management...
Detection of a paternally inherited fetal mutation in maternal plasma by the use of automated sequencingAna Bustamante-Aragones
Department of Genetics, Fundacion Jimenez Diaz, Avda Catolicos 2, 2840 Madrid, Spain
Ann N Y Acad Sci 1075:108-17. 2006..The automated sequencing enables the possibility of analyzing fetal sequences, at a nucleotide level, in order to detect mutations or polymorphisms which are distinguishable from maternal sequences...
Noninvasive prenatal diagnosis of monogenic disordersMarta Rodriguez de Alba
Genetics Department, Fundacion Jimenez Diaz, Avda Reyes Católicos n 2, Madrid 28040, Spain
Expert Opin Biol Ther 12:S171-9. 2012..As for other Mendelian disorders, until recently, their study was limited to those cases paternally inherited. Nevertheless, the new emerging technologies are also opening the scope to maternally inherited disorders...
Non-invasive prenatal diagnosis of single-gene disorders from maternal bloodAna Bustamante-Aragones
Genetics Service, Fundación Jiménez Diaz IIS, Avda Reyes Catolicos, 2 28040, Madrid, Spain
Gene 504:144-9. 2012..New technologies are opening NIPD to the analysis of maternally inherited fetal tracts. NIPD of trisomy 21 is the latest study derived from the use of next-generation sequencing (NGS)...
Double trisomy in spontaneous miscarriages: cytogenetic and molecular approachDan Diego-Alvarez
Human Genetics, Fundacion Jimenez Diaz, Avda Reyes Catolicos 2, 28040, Madrid, Spain
Hum Reprod 21:958-66. 2006....
